Microbiologia Medica最新文献

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Malaria and HIV sero-positivity: study on selected individuals at a tertiary healthcare centre in Port Harcourt, Nigeria 疟疾和艾滋病毒血清阳性:对尼日利亚哈科特港三级保健中心选定个人的研究

Microbiologia Medica Pub Date : 1900-01-01 DOI: 10.4081/mm.2019.8160

I. Okonko, Anwuli U. Osadebe, E. M. Okoli, Ego D. Eke

{"title":"Malaria and HIV sero-positivity: study on selected individuals at a tertiary healthcare centre in Port Harcourt, Nigeria","authors":"I. Okonko, Anwuli U. Osadebe, E. M. Okoli, Ego D. Eke","doi":"10.4081/mm.2019.8160","DOIUrl":"https://doi.org/10.4081/mm.2019.8160","url":null,"abstract":"Over 50% of the global population is vulnerable to malaria infection. An estimated 300 million malaria cases occur annually in the tropics with 90% of these in the sub-Sahara, a region that already suffers the greatest burden of HIV-1 infection. This study assessed the prevalence of HIV and malaria infections in a cohort of 200 undergraduates, consisting of 100 females and 100 males, attending the Health Centre at the University of Port Harcourt, Nigeria. Blood samples were screened for the presence of malaria and HIV, using SD Boline malaria Antigen P.F. test kit and Determine® HIV one step rapid Kit. The overall prevalence for HIV in this study was 2.5% while the overall prevalence of malaria was 1.5%. The prevalence of HIV based on gender was 2.0% and 3 % for females and males, respectively. For malaria, these values were 2.0% and 1.0% for females and males, respectively. No incident of co-infection was recorded in this study. The findings did not indicate any relationship between HIV seropositivity and malaria infection but underscored the low incidence of both malaria and HIV within the 17-26 age range and amongst relatively well-educated individuals. In spite of the low prevalence observed, there is still the need for awareness of HIV and Malaria prevention amongst university students. Further studies could be undertaken to investigate other relevant epidemiology parameters with regards to HIV and malaria in the tropics.","PeriodicalId":422034,"journal":{"name":"Microbiologia Medica","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126326447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

SCCmec typing and Panton-valentine leukocidin occurrence in methicillin resistant Staphylococcus aureus (MRSA) isolates from clinical samples of Ahvaz,southwest of Iran 伊朗西南部阿瓦士临床样本中耐甲氧西林金黄色葡萄球菌(MRSA)分离株的scmec分型和潘通-瓦伦丁白介素发生率

Microbiologia Medica Pub Date : 1900-01-01 DOI: 10.4081/mm.2019.8050

Nikou Bahrami, H. Motamedi, Seyyedeh Elham Reza Tofighi, M. Akhoond

{"title":"SCCmec typing and Panton-valentine leukocidin occurrence in methicillin resistant Staphylococcus aureus (MRSA) isolates from clinical samples of Ahvaz,southwest of Iran","authors":"Nikou Bahrami, H. Motamedi, Seyyedeh Elham Reza Tofighi, M. Akhoond","doi":"10.4081/mm.2019.8050","DOIUrl":"https://doi.org/10.4081/mm.2019.8050","url":null,"abstract":"Resistance to methicillin in methicillin resistant Staphylococcus aureus (MRSA) is dependent on mecA gene located on staphylococcal cassette chromosome (SCC). Both SCCmec type and Panton-Valentine leukocidin (PVL) affect S. aureus pathogenicity. Aim of this study was to investigate the prevalence of SCCmecA types and pvl genes among MRSA isolates from inpatients. During this cross-sectional study on 100 clinical isolates, following antibiotic susceptibility test, screening of mecA and pvl genes, as well as SCCmec typing, was done in a multiplex PCR technique. From the studied samples, 58 isolates were recognized as MRSA. The frequency of mecA and pvl was 58% and 4%, respectively. All of the MRSA were resistant to cefoxitin and had the highest sensitivity to chloramphenicol. The majority (77.5%) of MRSA was originated from wound samples. The SCCmec III was the most frequent type (22.4%) in these samples. The pvl positive isolates were from SCCmec IVb and V, thus meaning they are from CA-MRSA. These results show a high prevalence of MRSA in the studied region and a widespread prevalence of SCCmec I-V types. Furthermore, high prevalence of SCCmec III indicates the prevalence of multidrug resistant MRSA. This finding is a serious alarm for medical health care practitioners for the correct use of antibiotics in order to limit the spread of multidrug resistant strains. In addition, with regard to life threatening infections caused by pvl harbouring strains, early diagnosis and treatment of infections caused by these isolates should be mandatory.","PeriodicalId":422034,"journal":{"name":"Microbiologia Medica","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127052077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

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