{"title":"Status of Organ Donation and Solution of Organ Shortage in Korea","authors":"W. Cho","doi":"10.4285/JKSTN.2018.32.3.38","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.38","url":null,"abstract":"","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121149457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. J. Lee, B. Park, Sihyung Park, K. Park, Jin Han Park, I. Park, Y. Kim
{"title":"Basiliximab-Induced Non-Cardiogenic Pulmonary Edema in a Kidney Transplant Patient","authors":"Y. J. Lee, B. Park, Sihyung Park, K. Park, Jin Han Park, I. Park, Y. Kim","doi":"10.4285/JKSTN.2018.32.3.63","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.63","url":null,"abstract":"Induction therapy with basiliximab is widely administered after kidney transplantation to prevent acute rejection. Herein, we report a case of non-cardiogenic pulmonary edema induced by basiliximab. To the best of our knowledge, such case has not been reported to date in Korea. A 54-year-old man with polycystic kidney disease received kidney transplantation. As induction therapy, he was prescribed basiliximab. On day 4, the second dose of basiliximab was administered. The patient complained of acute hypoxia 23 hours later, which led to circulatory collapse. He was discharged 3 weeks later with stable renal function. Pulmonary edema was presumed to have been caused by increased pulmonary capillary permeability. A possible hypothesis for this event occurring after the second basiliximab injection is steroid-related effects. Non-cardiogenic pulmonary edema is a complication that might occur after basiliximab induction therapy. Physicians should be aware of this potentially life-threatening complication.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131343906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyo-In Choi, Jung Ae Hong, Min-Seok Kim, Sang Eun Lee, Sung-Ho Jung, H. Won, Jae-Joong Kim
{"title":"A Successful Pregnancy and Delivery after Heart Transplantation: The First Case Report from Korea","authors":"Hyo-In Choi, Jung Ae Hong, Min-Seok Kim, Sang Eun Lee, Sung-Ho Jung, H. Won, Jae-Joong Kim","doi":"10.4285/JKSTN.2018.32.3.69","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.69","url":null,"abstract":"Pregnancy following heart transplantation is a high-risk condition, requiring adequate maintenance of immunosuppressive drugs that enable proper graft function for optimal maternal and fetal outcomes. Here, we present the first case of successful child delivery in a patient who underwent heart transplantation in Korea. The 35-year-old female patient had become pregnant at 4 years after heart transplantation. The pregnancy progressed uneventfully, and the infant was healthy.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133055526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kang, Sooin Choi, Younhee Park, G. Park, H. R. Jang
{"title":"Results of Questionnaire Survey of Current Immune Monitoring Practice of Transplant Clinicians and Clinical Pathologists in Korea: Basis for Establishment of Harmonized Immune Monitoring Guidelines","authors":"E. Kang, Sooin Choi, Younhee Park, G. Park, H. R. Jang","doi":"10.4285/JKSTN.2018.32.2.13","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.2.13","url":null,"abstract":"Detection of significant alloimmune response, which affects graft function and survival by effective immune monitoring, is critical for treatment decision making. However, there is no consensus regarding immune monitoring (IM) for kidney transplantation (flow KT) in Korea. The IM protocol may be affected by the level of immunological risk, the methods of desensitization and the availabilities of resources such as laboratory support and cost of tests. Questionnaire surveys designed to identify the current practices regarding immune monitoring of KT among transplant clinicians and clinical pathologists in Korea and eventually provide a basis for the establishment of harmonized immune monitoring guidelines in KT were administered as part of a Korean Society for Transplantation Sponsored Research Project. The survey results revealed significant variations in IM protocols and interpretation of tests affecting treatment decisions between institutes. Moreover, the results revealed a need to expand the histocompatibility tests into high resolution HLA typing in multiple loci and non-HLA antibody tests that facilitate the epitope analysis and eventually virtual crossmatching. The results of the questionnaire survey from clinical pathologists are addressing the urgent need for the standardization of interpretation and harmonization of results reporting in single antigen bead based HLA antibody identification. Finally, communication between clinicians and clinical pathologists to meet the clinical expectations regarding various immune monitoring tests is needed.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129604785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ji, Ji-Yeun Chang, Chul-woo Yang, Seok-Goo Cho, B. Chung
{"title":"Bilateral Conjunctival Mucosa-Associated Lymphoid Tissue Type Lymphoma in a Kidney Transplant Recipient","authors":"E. Ji, Ji-Yeun Chang, Chul-woo Yang, Seok-Goo Cho, B. Chung","doi":"10.4285/JKSTN.2018.32.2.26","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.2.26","url":null,"abstract":"Lymphoproliferative disorder in a posttransplant setting has emerged as a difficult problem in kidney transplantation (KT). Lymphoma involving adnexa of the eye has rarely been reported due to scarcity of lymphoreticular tissue in the ocular area. This report presents a case of a 37-year-old KT recipient who was diagnosed with conjunctival mucosa-associated lymphoid tissue lymphoma with a chief complaint of seeing black spots. Unlike other post-transplant lymphoproliferative diseases associated with the Epstein-Barr virus (EBV) reactivation via immunosuppression, the lesion was not related to the virus. The patient received radiotherapy with concomitant conversion from the tacrolimus to the sirolimus. Overall, the results presented herein indicate lymphoma may be an important differential diagnosis when KT recipients complain of ocular discomfort.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124608647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anesthetic Management in Pediatric Liver Transplantation","authors":"Eun Jung Kim, B. Koo","doi":"10.4285/JKSTN.2018.32.3.31","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.31","url":null,"abstract":"An increasing number of pediatric patients undergo liver transplantation, and it has become an effective and definitive treatment of choice for pediatric end-stage liver disease patients. However, liver transplantation in pediatric patients differs greatly from that in older individuals with respect to not only surgical techniques, immunosuppression, and post-operative managements, but also to intraoperative anesthetic management. The present review provides an overview of the current development and clinical practices in anesthetic management of pediatric liver transplantation.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115047199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison Study of Outcomes of Deceased Donor Liver Transplantation before and after Korean Model for End-Stage Liver Disease (MELD) System: Single Center Experience","authors":"J. A. Lee, G. Choi, J. M. Kim, C. Kwon, J. Joh","doi":"10.4285/JKSTN.2018.32.1.7","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.1.7","url":null,"abstract":"Background: In June of 2016, the Model for End-Stage Liver Disease (MELD)-based allocation system replaced the Child-Turcotte-Pugh (CTP) score-based system for deceased donor liver transplantation (DDLT) in Korea. This study was conducted to reveal the changes before and after the MELD system. Methods: From January 2015 to March 2017, 71 patient datapoints were collected from recipients who underwent DDLT in a single center. Patients were divided into two groups according to the allocation system (41 in the MELD group, 30 in the CTP group). Results: The MELD score of the two groups differed significantly (36.8±4.5 in the MELD group, 26.0±8.1 in the CTP group, P=0.001). There was no difference in etiology for liver transplantation, 6-month survival rate, or in-hospital stay. However, complication rate and re-admission rate within the first 3 months were higher in the MELD group (78%, 56%). No one received a DDLT because of an incentive system for hepatocellular carcinoma. Conclusions: Despite the short-term follow-up period, the new allocation rule reflects the severity of the patients. Almost all patients who underwent DDLT when they had a high MELD score and then suffered from morbidity; however, this problem was associated with organ shortage, not the allocation system.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127186958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of B Cells in Transplantation Rejection","authors":"Tae Jin Kim","doi":"10.4285/JKSTN.2018.32.1.1","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.1.1","url":null,"abstract":"","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127406360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Youngmin Ko, H. Kwon, S. Chun, Y. Kim, J. Choi, S. Shin, J. Jung, Su-Kil Park, D. Han
{"title":"Predictors of Avascular Necrosis after Kidney Transplantation","authors":"Youngmin Ko, H. Kwon, S. Chun, Y. Kim, J. Choi, S. Shin, J. Jung, Su-Kil Park, D. Han","doi":"10.4285/JKSTN.2017.31.4.200","DOIUrl":"https://doi.org/10.4285/JKSTN.2017.31.4.200","url":null,"abstract":"Background: Risk factors for bone avascular necrosis (AVN), a common late complication after kidney transplantation (KT), are not well known. Methods: Patients that underwent living-donor KT at Asan Medical Center between January 2009 and July 2016 were included in this retrospective study to determine the incidence and risk factors for AVN after KT. Results: Among 1,570 patients that underwent living-donor KT, 33 (2.1%) developed AVN during a mean follow-up of 49.8±25.0 months. Additionally, AVN was diagnosed at a mean of 13.9±6.6 months after KT. The mean cumulative corticosteroid dose during the last follow-up in patients without AVN (9,108±3,400 mg) was higher than that that in patients with AVN (4,483±1,114 mg) until AVN development (P<0.01). More patients among those with AVN (n=4, 12.1%) underwent steroid pulse treatment because of biopsy-proven rejections during the first 6 months after KT than patients without AVN (n=68, 4.4%; P=0.04). Female (hazard ratio [HR], 2.29; P=0.04) and steroid pulse treatment during the first 6 months (HR, 2.31; P=0.02) were significant AVN risk factors as revealed by the Cox proportional multivariate analysis. However, no significant differences in rejection-free graft survival rates were observed between the two groups (P=0.67). Conclusions: Steroid pulse treatment within 6 months of KT and being female were independent risk factors for AVN development.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129870229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Ahn, K. Park, Jongha Park, H. Chung, Hojong Park, S. J. Park, H. Cho, J. S. Lee
{"title":"Clinical Outcomes and Contributors in Contemporary Kidney Transplantation: Single Center Experience","authors":"J. Ahn, K. Park, Jongha Park, H. Chung, Hojong Park, S. J. Park, H. Cho, J. S. Lee","doi":"10.4285/JKSTN.2017.31.4.182","DOIUrl":"https://doi.org/10.4285/JKSTN.2017.31.4.182","url":null,"abstract":"Clinical Outcomes and Contributors in Contemporary Kidney Transplantation: Single Center Experience Jae-Sung Ahn, M.D., Kyung Sun Park, M.D., Jongha Park, M.D., Hyun Chul Chung, M.D., Hojong Park, M.D., Sang Jun Park, M.D., Hong Rae Cho, M.D. and Jong Soo Lee, M.D. Division of Nephrology, Department of Internal Medicine, Biomedical Research Center, Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114293599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}