The Journal of The Korean Society for Transplantation最新文献

Angiotensin II type 1 receptor antibodies in kidney transplantation 肾移植中的血管紧张素II型1受体抗体

The Journal of The Korean Society for Transplantation Pub Date : 2019-03-31 DOI: 10.4285/JKSTN.2019.33.1.6

Hyeyoung Lee, E. Oh

引用次数: 0

Pediatric liver transplantation in Korea: long-term outcomes and allocations 韩国儿童肝移植:长期结果和分配

The Journal of The Korean Society for Transplantation Pub Date : 2019-03-01 DOI: 10.4285/JKSTN.2019.33.1.1

Sanghoon Lee, S. Lee

引用次数: 3

A case of Castleman disease that improved after kidney transplantation 肾移植后Castleman病好转1例

The Journal of The Korean Society for Transplantation Pub Date : 2019-03-01 DOI: 10.4285/JKSTN.2019.33.1.13

Heeryong Lee, J. An, D. R. Lee, Hyung Wook Choi, J. Oh, Joong-Kyung Kim

引用次数: 1

Donor Specific Antibody Negative Antibody-Mediated Rejection after ABO Incompatible Liver Transplantation ABO血型不相容肝移植后供体特异性抗体阴性抗体介导的排斥反应

The Journal of The Korean Society for Transplantation Pub Date : 2018-12-31 DOI: 10.4285/JKSTN.2018.32.4.108

Boram Lee, Soomin Ahn, Haeryoung Kim, Ho-Seong Han, Yoo-Seok Yoon, J. Cho, Y. Choi

引用次数: 0

Successful Treatment of Invasive Gastric Mucormycosis in a Kidney Transplant Recipient 肾移植受者侵袭性胃粘膜真菌病的成功治疗

The Journal of The Korean Society for Transplantation Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.104

H. Kim, S. Han, H. Park, Hyun-woo Kim, R. Hong, N. Choi, M. Shin, N. Yoon, Hyun Lee Kim, J. Chung, B. Shin

{"title":"Successful Treatment of Invasive Gastric Mucormycosis in a Kidney Transplant Recipient","authors":"H. Kim, S. Han, H. Park, Hyun-woo Kim, R. Hong, N. Choi, M. Shin, N. Yoon, Hyun Lee Kim, J. Chung, B. Shin","doi":"10.4285/JKSTN.2018.32.4.104","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.104","url":null,"abstract":"Type : Poster Presentation No. : PTL 031 Successful treatment of invasive gastric mucormycosis in kidney transplant recipient Hyun Woo Kim, Ha Yeol Park, Hyun Lee Kim, Jong Hoon Chung, Byung Chul Shin Department of Internal Medicine-Nephrology, Chosun University Hospital, Korea, Republic of Case Study: Mucormycosis is an extremely rare, but potentially life-threatening fungal infection. Gastrointestinal (GI) mucormycosis is rare and occurs primarily in the extremely malnourished patients especially infants or children. A 55-year-old man with end-stage renal disease due to diabetic nephropathy underwent deceased donor kidney transplantation on 2years ago. He complained of abdominal pain and distension on 3days ago at admission. A computed tomography (CT) scan revealed diffuse gastric wall thickening. A gastrointestinal (GI) endoscopy showed huge grey colored elevated necrotic debris surrounded by erythematous erosive mucosa at antrum to upper body. Microscopic examination obtained from a GI endoscopic specimen demonstrated peptic detritus with numerous nonseptate mucor hyphae was noted in the mucosa and submucosa. Mucormycosis was diagnosed according to the clinical findings and morphological features. A total gastrectomy was performed and antifungal agent was supplied. Microscopic examination obtained from a surgical specimen demonstrated invasive mucormycosis with numerous fungal hyphae with invasion into mucosa to subserosa. The patient and graft successfully treated to the infection with total gastrectomy and antifungal therapy. GI endocscopy showed gastric mucormycosis","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123497942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

ABO Incompatible Living Donor Liver Transplantation: A Single Center Experience ABO血型不相容活体供肝移植:单一中心经验

The Journal of The Korean Society for Transplantation Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.84

Seung Hoon Lee, H. Choi, Y. You, D. G. Kim, G. Na

{"title":"ABO Incompatible Living Donor Liver Transplantation: A Single Center Experience","authors":"Seung Hoon Lee, H. Choi, Y. You, D. G. Kim, G. Na","doi":"10.4285/JKSTN.2018.32.4.84","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.84","url":null,"abstract":"Background: This study examined the outcomes of ABO incompatible living donor liver transplantation (LDLT). The changes in the immunologic factors that might help predict the long term outcomes were also studied. Methods: Twenty-three patients, who underwent ABO incompatible LDLT from 2010 to 2015, were reviewed retrospectively. The protocol was the same as for ABO compatible LDLT except for the administration of rituximab and plasma exchange. The clinical outcomes and immunologic factors, such as isoagglutinin titer and cluster of differentiation 20+ (CD20+) lymphocyte levels were reviewed. Results: The center showed a 3-year survival of 64% with no case of antibody-mediated rejection. When transplantation-unrelated mortalities (for example, traffic accidents and myocardial infarction) were removed from statistical analysis, the 3-year survival was 77.8%. Although isoagglutinin titers continued to remain at low levels, the CD20+ lymphocyte levels recovered to the pre-Rituximab levels at postoperative one year. Conclusions: As donor shortages continue, ABO incompatible liver transplantation is a feasible method to expand the donor pool. On the other hand, caution is still needed until more long-term outcomes are reported. Because CD20+ lymphocytes are recovered with time, more immunologic studies will be needed in the future.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124512694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation 基于危险因素的肾移植术后早期和晚期肺囊虫肺炎选择性预防策略的提出

The Journal of The Korean Society for Transplantation Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.92

Ho Lee, A. Han, Chanjoong Choi, Sanghyun Ahn, S. Min, S. Min, Hajeong Lee, Y. S. Kim, J. Yang, J. Ha

{"title":"Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation","authors":"Ho Lee, A. Han, Chanjoong Choi, Sanghyun Ahn, S. Min, S. Min, Hajeong Lee, Y. S. Kim, J. Yang, J. Ha","doi":"10.4285/JKSTN.2018.32.4.92","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.92","url":null,"abstract":"Background: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol and proposes an individualized risk-based prophylaxis protocol. Methods: The PJP incidence and risk factors during the first 6 months (early PJP) and afterwards (late PJP) was assessed in renal transplant recipients with (prophylaxis group) and without (no-prophylaxis group) 6-month PJP prophylaxis. Results: In 578 patients, there were 39 cases of PJP during a median follow-up of 51 months. Renal adverse events were encountered frequently during trimethoprim-sulfamethoxazole prophylaxis, leading to premature discontinuation. Patients without the prophylaxis had a significantly higher incidence of early PJP (n=27, 6.6%) compared to patients with the prophylaxis (n=0). The incidence of late PJP was 2.2%, without between-group differences. The factors associated with early PJP were preoperative desensitization and acute rejection within 1 month, whereas late PJP was associated with age, deceased donor transplant, and acute rejection requiring antithymocyte globulin treatment. Conclusions: Based on the simulation results of several risk-based scenarios, the authors recommend universal prophylaxis up to 6 months post-transplant and extended selective prophylaxis in patients aged ≥ 57 years and those with a transplant from deceased donors.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126345605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year 环孢素下监测肾移植患者霉酚酸谷浓度有助于减少1年内急性排斥反应

The Journal of The Korean Society for Transplantation Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.75

J. Rhu, Kyo-Won Lee, J. Park, Sung Joo Kim

{"title":"Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year","authors":"J. Rhu, Kyo-Won Lee, J. Park, Sung Joo Kim","doi":"10.4285/JKSTN.2018.32.4.75","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.75","url":null,"abstract":"Background: This study was designed to analyze the clinical usefulness of mycophenolic acid trough concentration monitoring in kidney transplantation patients who were maintained with cyclosporine. Methods: The data of patients who underwent mycophenolic acid trough concentration monitoring after their first kidney transplant between November 2006 and August 2013 and were prescribed with cyclosporine, mycophenolate, and methylprednisolone were reviewed retrospectively. Cox analysis was used to analyze the risk factors for acute rejection within 1 year post-transplantation. Results: Among 90 patients, 41 (45.6%) achieved both the target levels of cyclosporine and mycophenolic acid, while three patients (3.3%) failed to achieve the target level of either cyclosporine or mycophenolic acid. Nine patients (10.0%) only achieved the mycophenolic acid target level and 37 patients (41.1%) only achieved the cyclosporine target level. While patients who achieved only the mycophenolic acid target concentration had no statistically increased risk compared to patients who achieved both target levels (hazard ratio [HR], 1.569; 95% confidence interval [CI], 0.316 to 7.778; P=0.581), patients who only achieved the cyclosporine target concentration showed an increased risk of rejection compared to the both achievement group (HR, 4.112; 95% CI, 1.583 to 10.683; P=0.004). Patients who had no achievement in the target levels showed significantly increased rejection risk compared to the patients who achieved both target levels (HR, 17.811; 95% CI, 3.072 to 103.28; P=0.001). Conclusions: Mycophenolic acid trough concentration monitoring combined with cyclosporine trough concentration monitoring is useful for avoiding acute cellular rejection if the first 1 year post-transplantation.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130055799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Bortezomib on the Management of Immediate Postoperative Refractory Antibody-Mediated Rejection after Kidney Transplantation 硼替佐米对肾移植术后即刻难治性抗体介导排斥反应的影响

The Journal of The Korean Society for Transplantation Pub Date : 2018-09-01 DOI: 10.4285/JKSTN.2018.32.3.49

So-Jeong Kim, K. Jun, J. Hwang, B. Chung, Chul-woo Yang, I. Moon, Ji-Il Kim, Mi-hyeong Kim

引用次数: 0

Bortezomib Treatment for Refractory Antibody-Mediated Rejection Superimposed with BK Virus-Associated Nephropathy during the Progression of Recurrent C3 Glomerulonephritis 硼替佐米治疗复发性C3肾小球肾炎进展期间合并BK病毒肾病的难治性抗体介导排斥反应

The Journal of The Korean Society for Transplantation Pub Date : 2018-09-01 DOI: 10.4285/JKSTN.2018.32.3.57

W. Do, Jonghyo Lee, Kyung Joo Kim, Man-Hoon Han, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim, Jang-Hee Cho, Youngae Yang, Min-Ji Kim, I. Hwang, Kyu Yeun Kim, T. Yim, Yong Jin Kim

引用次数: 0