EMJ Diabetes最新文献_第4页

Screening for Heart Failure in Diabetes: A Way to Reduce Its Prevalence? A Proof of Concept of a Risk Assessment Tool 糖尿病心衰筛查:降低其患病率的一种方法?风险评估工具的概念证明

EMJ Diabetes Pub Date : 2021-11-09 DOI: 10.33590/emjdiabet/21-00138

Pablo Millares Martin, Rosa Bobet Reyes

引用次数: 0

Metformin: Arguments for Maintaining its Position as First-Line Pharmacological Treatment in Type 2 Diabetes Mellitus 二甲双胍:维持其作为2型糖尿病一线药物治疗地位的争论

EMJ Diabetes Pub Date : 2021-11-09 DOI: 10.33590/emjdiabet/21-00191

C. Stehouwer

引用次数: 0

Disparities in Diabetes Care 糖尿病护理的差异

EMJ Diabetes Pub Date : 2021-11-09 DOI: 10.33590/emjdiabet/21-00194

Adrian Li, M. Whyte

引用次数: 2

Fast Progression of Diabetic Retinopathy with SARS-CoV-2 Infection 糖尿病视网膜病变伴SARS-CoV-2感染的快速进展

EMJ Diabetes Pub Date : 2021-05-17 DOI: 10.33590/EMJDIABET/20-00254

Yigit Akduman, W. Anderson, S. Saxena

引用次数: 4

Reproductive Dysfunctions in Males with Type 2 Diabetes Mellitus: An Updated Review 男性2型糖尿病患者的生殖功能障碍:最新综述

EMJ Diabetes Pub Date : 2020-11-10 DOI: 10.33590/emjdiabet/20-00171

S. Ray, Subhodip Pramanik

{"title":"Reproductive Dysfunctions in Males with Type 2 Diabetes Mellitus: An Updated Review","authors":"S. Ray, Subhodip Pramanik","doi":"10.33590/emjdiabet/20-00171","DOIUrl":"https://doi.org/10.33590/emjdiabet/20-00171","url":null,"abstract":"Deterioration in reproductive functions is one of the most serious complications of Type 2 diabetes mellitus (T2DM). Neuropathy, angiopathy, oxidative stress, and psychological deviation are the important causative factors in developing reproductive dysfunctions in diabetes. In males, the principal complications are erectile dysfunction (ED), ejaculatory disorders, and functional hypogonadism. Low serum testosterone is frequently observed in males with T2DM but the neuroendocrine pathophysiology is yet to be defined; this reduction in testosterone levels decreases libido. Evaluation of testosterone levels of male diabetic patients with hypogonadism symptoms is recommended. Hypogonadal males with diabetes might benefit from testosterone replacement therapy. However, there is a need for adequately powered long-term studies in this context. Impairment in sexual function is a common complication in males with diabetes. The pathophysiology of sexual dysfunction in diabetes is multifactorial. Males with diabetes have a >3-fold increase in the risk of ED compared to their nondiabetic counterparts. Phosphodiesterase type 5 inhibitors should be considered as first-line therapy in males with T2DM and ED. Nearly 50% of male diabetic patients presented some degree of subfertility or infertility. Alterations in sperm parameters and hormone levels can contribute to diabetes-related male infertility. Endocrinologists, diabetologists, and physicians should address sexual complaints of their patients since these problems can significantly impair their quality of life.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"PP 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126528476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Metformin: From Immediate Release to Extended Release Formula, Effectiveness, And Safety in Patients With Chronic Kidney Disease 二甲双胍:从立即释放到缓释配方，在慢性肾病患者中的有效性和安全性

EMJ Diabetes Pub Date : 2020-11-10 DOI: 10.33590/emjdiabet/19-00177

G. Derosa, R. Rivera, A. D'Angelo, P. Maffioli

引用次数: 0

Gestational Diabetes: Comparison of Random and Fasting Plasma Glucose as Modalities of Screening 妊娠期糖尿病:随机和空腹血糖作为筛查方式的比较

EMJ Diabetes Pub Date : 2020-11-10 DOI: 10.33590/emjdiabet/20-00119

C. Chukwunyere, D. Awonuga, O. Adesina, I. Udenze

{"title":"Gestational Diabetes: Comparison of Random and Fasting Plasma Glucose as Modalities of Screening","authors":"C. Chukwunyere, D. Awonuga, O. Adesina, I. Udenze","doi":"10.33590/emjdiabet/20-00119","DOIUrl":"https://doi.org/10.33590/emjdiabet/20-00119","url":null,"abstract":"Objective: Gestational diabetes is glucose intolerance of varying severity with onset in the index pregnancy. This study aimed to compare fasting plasma glucose (FPG) with random plasma glucose (RPG) among pregnant females as methods of screening for gestational diabetes.\u0000\u0000Methods: A cross-sectional study of 100 pregnant females selected to have screening for gestational diabetes between gestational ages of 24 and 28 weeks using RPG and FPG. All the subjects had 75 g oral glucose tolerance test as the gold standard. Venous plasma glucose assay was performed using glucose oxidase method.\u0000\u0000Results: The prevalence of gestational diabetes was 29% using FPG cut-off ≥5.1 mmol/L and 6% using RPG cut-off ≥7.8 mmol/L. The RPG cut-off ≥11.1 mmol/L gave the lowest prevalence rate of 2%, while 75 g oral glucose tolerance test (gold standard test) gave the highest prevalence rate of 30%. RPG cut-off ≥7.8 mmol/L revealed a positive-predictive value of 66.7%, negative-predictive value of 72.3%, and area under the curve of 0.845 compared with FPG level at threshold of 5.1 mmol/L, which gave positive-predictive value of 93.1%, negative-predictive value of 95.8%, and area under the curve 0.920.\u0000\u0000Conclusion: This study revealed that FPG threshold of 5.1 mmol/L alone performed excellently as a screening test.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121500583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Psychological Aspects of Diabetes 糖尿病的心理方面

EMJ Diabetes Pub Date : 2020-11-10 DOI: 10.33590/emjdiabet/20-00174

N. A. Bhat, K. Muliyala, S. Chaturvedi

{"title":"Psychological Aspects of Diabetes","authors":"N. A. Bhat, K. Muliyala, S. Chaturvedi","doi":"10.33590/emjdiabet/20-00174","DOIUrl":"https://doi.org/10.33590/emjdiabet/20-00174","url":null,"abstract":"Diabetes is fundamentally a chronic metabolic disorder, yet it has established psychological connections and consequences. The present article offers an overview of some of the established findings with respect to the psychological aspects of diabetes among adults and adolescents. This narrative review describes the psychological impact of diabetes and the manner in which psychological functioning of the individual affects the development, management, and outcome of diabetes. Diabetes can lead to a great deal of distress, common mental health problems such as anxiety, depression, and sleep disorders, and can increase the risk of suicide. It also affects cognitive functioning across multiple domains such as attention, concentration, memory, executive function, and information processing speed. Diabetes is a burdensome life condition that significantly reduces quality of life. Personality characteristics can have both positive and negative impacts on self-management of diabetes, and some personality profiles, especially the distressed/Type D personality, are indicative of poor prognosis and greater chances of developing medical complications. Psychological interventions such as cognitive behaviour therapy, acceptance and commitment therapy, behavioural activation, and counselling strategies such as educational programmes, problem solving training, and motivational interviewing have proven very effective in coping with diabetes distress, managing comorbid mental health problems, and increasing adherence to self-care and antidiabetic behaviours. Additionally, yogic practices have also shown promising results for self-management of diabetes. Paediatric diabetes especially presents unique psychosocial challenges to patient management and affects academic performance of children and career choices of affected individuals.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126376084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Kidney Disease: Improving Global Outcomes (KDIGO) New Guideline for Diabetes Management in Chronic Kidney Disease: A Meet-the-Expert Session 肾病:改善全球预后(KDIGO)慢性肾病糖尿病管理新指南:专家见面会

EMJ Diabetes Pub Date : 2020-10-14 DOI: 10.33590/emjdiabet/201014

P. Rossing, Tami Sadusky

{"title":"Kidney Disease: Improving Global Outcomes (KDIGO) New Guideline for Diabetes Management in Chronic Kidney Disease: A Meet-the-Expert Session","authors":"P. Rossing, Tami Sadusky","doi":"10.33590/emjdiabet/201014","DOIUrl":"https://doi.org/10.33590/emjdiabet/201014","url":null,"abstract":"Prof de Boer opened this virtual seminar on the new Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on diabetes management in chronic kidney disease (CKD), which is the first set of KDIGO guidance on this topic. Prof de Boer emphasised that the aim of the guideline was to generate a useful resource for clinicians and patients, to address relevant questions with actionable recommendations supplemented by practice points, to take on controversial topics when sufficient evidence was available, and to communicate findings clearly and concisely. The scope of the new guideline includes patients with Type 1 diabetes mellitus, Type 2 diabetes mellitus, and all severities of CKD, including patients treated with dialysis or kidney transplantation. The new guideline also includes recommendations related to lifestyle, pharmacotherapy, and the organisation of healthcare systems, addressed using systematically identified data from randomised controlled trials. Topics such as blood pressure control and lipid management and prevention of and screening for diabetes are not covered by the new KDIGO guideline and have been addressed either in prior KDIGO publications or in other international guidelines.\u0000\u0000After his introduction, Prof de Boer handed over to Prof Rossing, who offered a detailed overview of the new guidelines, and Ms Sadusky, who highlighted the contribution of patients in the development of the guidelines. Prof Rossing and Ms Sadusky concluded the seminar by emphasising the importance of shared decision-making, where the patient is involved in defining individualised treatment goals, and the critical need for a team-based approach in the care of patients with diabetes and CKD.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133074607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

COVID-19: Is it time to revisit the research on calcium channel drug targets? 2019冠状病毒病:是时候重新审视钙通道药物靶点的研究了吗?

EMJ Diabetes Pub Date : 2020-06-08 DOI: 10.33590/emjdiabet/200608

M. Balasubramanyam

引用次数: 4