EMJ Diabetes最新文献_第9页

A Practical Review of Insulin Pen Devices 胰岛素笔装置的实用综述

EMJ Diabetes Pub Date : 2014-10-01 DOI: 10.33590/emjdiabet/10312668

Teresa Pearson

{"title":"A Practical Review of Insulin Pen Devices","authors":"Teresa Pearson","doi":"10.33590/emjdiabet/10312668","DOIUrl":"https://doi.org/10.33590/emjdiabet/10312668","url":null,"abstract":"Since the advent of insulin pens in 1985, there have been ongoing improvements providing several advantages over the traditional vial and syringe method of insulin delivery. In recent years, pens have become increasingly user-friendly, and some models are highly intuitive to use, requiring little or no instruction. Despite this progress, there remains to be disparity in access to insulin pens to people with diabetes in various countries. There is a need for improved awareness of the benefits of insulin pens among healthcare professionals. Continual advances have been made to address patient needs such as improved technology to make them easier to use; less painful; more discreet and convenient; and more accuracy for small doses of insulin, as well as the incorporation of a memory function, all contribute to an insulin delivery device that allows the patient to better manage their diabetes anytime and anyplace, without the bulk and challenge of carrying a vial and syringe. These advances have resulted in increased patient satisfaction with insulin pens and most importantly, all of these benefits improve adherence and result in improved clinical outcomes. This review highlights these benefits of insulin pen use and presents the issues to be considered when helping patients decide on the insulin pen that will best suit their needs.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132850114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Membrane Flexibility and Cellular Energy Management in Type 2 Diabetes, Gestational Diabetes, and Obesity 2型糖尿病、妊娠糖尿病和肥胖的膜柔韧性和细胞能量管理

EMJ Diabetes Pub Date : 2014-10-01 DOI: 10.33590/emjdiabet/10313367

R. Weijers

引用次数: 6

Detection and Early Lifestyle Intervention in Those at Risk of Type 2 Diabetes 2型糖尿病危险人群的检测和早期生活方式干预

EMJ Diabetes Pub Date : 2014-10-01 DOI: 10.33590/emjdiabet/10313999

C. Edwardson, L. Gray, T. Yates, S. Barber, K. Khunti, M. Davies

{"title":"Detection and Early Lifestyle Intervention in Those at Risk of Type 2 Diabetes","authors":"C. Edwardson, L. Gray, T. Yates, S. Barber, K. Khunti, M. Davies","doi":"10.33590/emjdiabet/10313999","DOIUrl":"https://doi.org/10.33590/emjdiabet/10313999","url":null,"abstract":"The prevalence of Type 2 diabetes mellitus (T2DM) has reached epidemic proportions in recent years. It is now widely recognised that T2DM is a highly preventable disease. This article highlights the evidence to date for the prevention of T2DM. In order to prevent or delay the onset of T2DM, people at high risk of developing the condition need to be identified and treated using evidenced-based and cost-effective approaches. Risk scores offer a quick, simple way of identifying those at high risk for invitation to screening programmes without the need for initial invasive tests. Best practice guidance, including those from National Institute for Health and Clinical Excellence (NICE) in the UK and the European wide IMAGE project, recommend that a two-stepped approach whereby the identification of a high-risk status through risk score technology is confirmed by a blood test. Once identified, those at high risk can be offered a lifestyle intervention programme. Landmark diabetes prevention studies show that lifestyle intervention, focusing on increases in physical activity, improvements in diet, and reductions in weight, reduces the risk of progression to T2DM by 30-60% and can have lasting benefits after the active intervention ceases. Recent pragmatic prevention programmes also demonstrate encouraging results. However, research targeted to the prevention of T2DM must continue to be expanded to find the most effective methods of T2DM prevention in various societies and cultural settings. There is also a need for research focusing on young people at high risk and novel approaches, such as targeting a reduction in sitting and use of technology, to support behaviour change.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128385735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Diabetes Mellitus and Periodontitis: Signs of a Bidirectional Relationship 糖尿病和牙周炎:双向关系的迹象

EMJ Diabetes Pub Date : 2013-11-28 DOI: 10.33590/emjdiabet/10310009

P. Gümüş, N. Buduneli

引用次数: 15

Mortality in Patients with Pad with Respect to Glycaemic Status: A Review 糖尿病患者的死亡率与血糖状况:综述

EMJ Diabetes Pub Date : 2013-11-28 DOI: 10.33590/emjdiabet/10313308

I. Hjellestad, T. Jonung

{"title":"Mortality in Patients with Pad with Respect to Glycaemic Status: A Review","authors":"I. Hjellestad, T. Jonung","doi":"10.33590/emjdiabet/10313308","DOIUrl":"https://doi.org/10.33590/emjdiabet/10313308","url":null,"abstract":"Peripheral arterial disease (PAD) is a manifestation of atherosclerosis. Atherosclerosis is a chronic inflammatory process and nonenzymatic glycation is a process of major interest in relation to how risk factors promote atherogenesis. A strong association between diabetes mellitus (DM) and PAD has been established, and the association is related to the duration of DM. Previous studies have revealed a higher prevalence of DM in patients with PAD compared to general populations and populations at risk of developing DM. The typical dyslipidaemia found in patients with PAD is similar to that found in patients with insulin resistance, and an association of HbA1c with atherogenic dyslipidaemia is described. HbA1c has been described as a predictor for DM and of micro and macrovascular disease. 5-year all-cause mortality in PAD is 19–37% and 10-year all-cause mortality is 42-54%. The mortality in PAD increases with age, with the severity of the peripheral vascular disease, and with the coexistence of PAD with coronary artery disease and DM. Patients with DM, defined by glucose criteria, and PAD have an increased mortality compared with patients with PAD alone. Recent studies have shown an association of HbA1c levels with vascular complications and death in patients with DM. No studies could be found that aimed to validate HbA1c against glucose criteria as a predictor for mortality in patients with PAD. Further studies on patients with PAD and DM are needed to identify which is the best diagnostic method to predict mortality in PAD with respect to glycaemic status: the glucose parameters or the HbA1c.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133936317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus 糖尿病患者动态血压监测与血压昼夜节律

EMJ Diabetes Pub Date : 2013-11-28 DOI: 10.33590/emjdiabet/10313118

E. Matteucci, O. Giampietro

{"title":"Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus","authors":"E. Matteucci, O. Giampietro","doi":"10.33590/emjdiabet/10313118","DOIUrl":"https://doi.org/10.33590/emjdiabet/10313118","url":null,"abstract":"Systolic and diastolic blood pressures display a circadian rhythmicity that can be assessed by 24-hour ambulatory blood pressure monitoring and analysed using the cosinor procedure. Altered characteristics to the circadian rhythm of blood pressure, which may result in adverse health outcomes, have been observed in both prediabetes and diabetes. We have investigated the circadian variability of blood pressure in patients with type 1 and type 2 diabetes. Chronobiologically interpreted ambulatory blood pressure monitoring uncovered not only midline estimating statistic of rhythm (MESOR)-hypertension and circadian hyper-amplitude-tension, but also circadian ecphasia (an odd timing of the daily blood pressure swing). Diastolic blood pressure acrophases were found to be phase shifted to earlier along the time axis only in patients with diabetes, but not in those with essential hypertension. Several mechanisms, from changes in nutrient-dependent signalling pathways to diabetic autonomic neuropathy, can contribute to alterations of circadian time structures in diabetic people. The chronology of blood pressure changes in animal models of diabetes and hypertension suggests that a chronobiological approach to the diagnosis of blood pressure disorders could offer advantages, but longitudinal studies in humans are needed to determine its potential relevance in hypertension associated with diabetes.","PeriodicalId":418035,"journal":{"name":"EMJ Diabetes","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124820630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is it Time to Transform our Treatment of Type 2 Diabetes? 是时候改变我们对2型糖尿病的治疗了吗?

EMJ Diabetes Pub Date : 2013-11-28 DOI: 10.33590/emjdiabet/10310247

J. Viney

引用次数: 0

Interview: Naveed Sattar 采访:Naveed Sattar

EMJ Diabetes Pub Date : 1900-01-01 DOI: 10.33590/emjdiabet/10158880

N. Sattar

引用次数: 0

Multidisciplinary Approach to Management and Care of Patients with Type 2 Diabetes Mellitus 2型糖尿病患者的多学科管理与护理

EMJ Diabetes Pub Date : 1900-01-01 DOI: 10.33590/emjdiabet/10314374

S. Bain, M. Cummings, G. Mckay

引用次数: 7