Cardiometry最新文献

{"title":"Effectiveness of Manchester triage flow model regarding patients’ waiting time in Bahria international hospital Lahore, Pakistan","authors":"M. Shaheen, M. Afzal, M. Mukhtar","doi":"10.18137/cardiometry.2023.29.9598","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.9598","url":null,"abstract":"The triage system is meant to be implemented in all (Accidental & Emergency Departments) so as to help and determine the relative priority of individual patient needs. Emergency patients are to be given immediate treatment, while those with non-acute symptoms may have to wait longer (Lucke et al., 2021). Assessment process during the triage need to be balanced with the extent of patient flow, as expanding the assessment process during triage may slow down the patient flow and may lead to delay in emergency service provision (Lucke et al., 2021).Through the use of computer-generated reports, archival data records for two months from the ED of the Bahria International Hospital in Lahore, Pakistan to assess the effectiveness of patients triage flow model. The results of this quantitative study showed that the patient flow model had a considerable temporal effect. Including 16 females, 25 were male and 25% average waiting was more than 240 mints. The ability to decrease patient wait times while enhancing patients quality of care and health outcomes is one of the social change implications. A quantitative study would produce data that would assist medical staff by shortening the wait times for patients.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"179 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Some Different Blood Anticoagulants on Rabbits Plasma Biochemical Parameters under Different Temperatures","authors":"E.N.J. Al-Obaidy, M.M. Ismail, M.Z. Muhi","doi":"10.18137/cardiometry.2023.29.111115","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.111115","url":null,"abstract":"The aim of present study was to compare the effect of Ca chelating anticoagulants (EDTA, citrate and oxalate) and antithrombin anticoagulant (heparin) on some rabbits plasma biochemical parameters at room temperature 25℃ and extreme temperatures -18℃and 50℃ for 1hr. Five male rabbits weighting between 800-1000gm, kept in the animal house /College of Veterinary Medicine/University of Diyala, under 12:12 dark light cycle with ad libtum food and water in individual cages (60cm,40cm) during November and December /2022. Four ml of blood samples were collected by cardiac puncture (23G needle) into four tubes contain anticoagulants: (EDTA, citrate, oxalate and heparin)one ml of blood for each tube; then the blood samples were kept at :room temperature 25℃, waterbath50℃ and refrigerator -18 ℃, for 1hr then put in centrifuge at 3000rpm for 15min. From total examined blood samples =24 for each Ca chelating anticoagulants (EDTA, citrate and oxalate) and antithrombin anticoagulant (heparin) after 1hr under in 25c℃ , -18℃ and 50℃. The both groups of anticoagulants (Ca chelating and antithrombin) showed no significant differences P>0.05 between them in level of biochemical parameters (glucose, total protein, cholesterol and urea) after 1 hr at 25C; on the other hand significant increase in plasma glucose, total protein and cholesterol beside significant decrease in plasma urea of Ca chelating anticoagulants after 1hr at -18C and 50C as compare with antithrombin anticoagulant. In conclusion; heparin was more effective than Ca chelating anticoagulant in preserve plasma biochemical parameters within normal values under extreme cool and hot condition.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139302152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of bioinspired methods and means in medicine","authors":"A.V. Yarovoy, M.P. Deberdeev, A.O. Chepiga, I. M. Borodyansky","doi":"10.18137/cardiometry.2023.29.6266","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.6266","url":null,"abstract":"This review examines the role of bioinspired methods in medicine and their potential for improving human health, as well as in the treatment of various diseases. The authors highlight the genetic algorithm and recommendation systems as one of the main tools used in bioinspired methods. This methodology is considered in various aspects of medical practice, such as diagnosis, therapy, prognosis, sports medicine and selection of the correct treatment. Various areas of application of bioinspired methods in medicine are considered. The authors provide an overview of research and development based on the principles of evolutionary modeling. In addition, ethical, economic, and legal aspects of the use of bioinspired methods in medicine are discussed. An integrated approach and a unique view on the role of bioinspired methods and means in medical practice is presented, which reflects modern views on the prospects for research and development of this area.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139291305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of diagnostic accuracy between MRI and CT scans in detecting skull base ENT pathologies","authors":"A. Iqbal, S. Khursheed, M. Ibrahim, R. Ali, S.B. Munir, T.H. Khan, K. Lodhi","doi":"10.18137/cardiometry.2023.29.103110","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.103110","url":null,"abstract":"Skull base ENT (Ear, Nose, and Throat) pathologies present a diagnostic challenge due to their intricate location. Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scans are commonly used diagnostic tools for detecting these pathologies. This study aims to associate the diagnostic exactness of MRI and CT scans in detecting skull base ENT pathologies. Aim: The primary objective of our current research is to assess and associate the diagnostic accuracy of MRI and CT scans in detecting skull base ENT pathologies, including tumors, infections, and congenital anomalies. Methods: Researchers led the retrospective study of medical records from the cohort of patients with suspected skull base ENT pathologies who underwent both MRI and CT scans. Imaging reports were reviewed by experienced radiologists blinded to the clinical outcomes. Diagnostic accuracy metrics, including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), were calculated for each modality. McNemar's test was utilized to assess statistical significance of differences in diagnostic accuracy between MRI and CT. Results: An overall of 150 individuals were involved in our research. MRI demonstrated a sensitivity of 87%, specificity of 92%, PPV of 85%, and NPV of 93% in detecting skull base ENT pathologies. CT scans showed a sensitivity of 72%, specificity of 78%, PPV of 70%, and NPV of 80%. The diagnostic accuracy of MRI was significantly higher than that of CT for detecting these pathologies (p < 0.05). Subgroup analyses were performed for different types of pathologies, providing valuable insights into the strengths and limitations of each imaging modality. Conclusion: This comparative analysis highlights the superior diagnostic accuracy of MRI over CT scans in detecting skull base ENT pathologies. MRI offers higher sensitivity and specificity, making it a valuable tool for clinicians in the evaluation and management of individuals with these conditions. However, CT may still have a role in specific cases where MRI is contraindicated or for initial screening. Clinicians should consider these findings when selecting the most appropriate imaging modality for patients with suspected skull base ENT pathologies.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"141 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139297824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE ASSESSMENT OF CYTOTOXICITY AND ACCUMULATION OF LITHIUM AND BORON IN SKIN MELANOMA CELLS IN VITRO","authors":"A. Kasatova, Y. Taskaeva, I. Razumov, S. Taskaev, N.P. Bgatova","doi":"10.18137/cardiometry.2023.29.conf.10","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.conf.10","url":null,"abstract":"Boron neutron capture therapy (BNCT) is a binary radiation therapy modality based on the high capability of the non-radioactive isotope 10B to absorb thermal neutrons. The use of alternative isotope 6Li for lithium neutron capture therapy (LiNCT) may be a promising area in the treatment of oncological diseases, but at present the data on the possibilities of lithium accumulation in tumor cells are limited to some sporadic studies.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHANGES IN THE ENERGY ACTIVITY OF BLOOD LYMPHOCYTES AND MORPHOMETRIC PARAMETERS OF THE BRAIN IN A MODEL OF BRAIN DAMAGE IN RATS","authors":"N. V. Khunderyakova, V.P. Medvedeva, T.V. Polyakova, V.V. Mironov, I.V. Bulgin, G.R. Mikhailova, N.V. Penkov, G.D. Mironova","doi":"10.18137/cardiometry.2023.29.conf.13","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.conf.13","url":null,"abstract":"It is known that Parkinson’s disease (PD) being a neurodegenerative disease is accompanied by increased levels of reactive oxygen species, oxidative stress and impaired mitochondrial activity. It has been shown that the development of malignant tumors can be accompanied by disorders that mimic PD. In this regard, shifts in cellular metabolism associated with the development of true PD are of interest.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"171 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139296747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and epidemiological features of the detection and course of the infectious disease tuberculosis depending on the presence of concomitant pathology","authors":"N.V. Davletbaeva, R.A. Sharipov, E.A. Daminov, R.N. Davletbaev, T.E. Tyulkova","doi":"10.18137/cardiometry.2023.29.7479","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.7479","url":null,"abstract":"The article is devoted to the most pressing issues of studying the clinical and epidemiological features concerning the detection and course of tuberculosis infection in patients with concomitant pathologies. Such pathologies include cancer, diseases of the endocrine system, of the respiratory system (chronic bronchitis, pneumoconiosis), gastric ulcer, pathology of the urinary system, exhaustion due to insufficient nutrition, smoking. Using genetically engineered biological drugs (GEBPs) in practice reduces the activity of inflammatory phenomena due to suppression of the immune response, but increases the risk of developing infectious diseases, primarily tuberculosis. Immunosuppressive therapy in organ transplant patients is also associated with the risk of developing tuberculosis. A special nature of immune disorders develops during HIV infection, a comorbid disease in patients with tuberculosis. The diseases listed above create a medical risk group in patients with immunocompromise, which is the basis for the development of tuberculosis. In addition to the risk of developing infection, patients with concomitant diseases have unfavorable results from treatment of tuberculosis, which does not allow achieving abacillation in a short time, thereby maintaining a reservoir of infection in society. In this regard, the purpose of our research was to study the clinical and epidemiological features of the detection and course of tuberculosis infection in patients with concomitant pathology A study was conducted using a continuous sampling method for the period from December 2020 to August 2021. 67 medical records of an inpatient at the state budgetary healthcare institution “Republican Clinical Anti-TB Dispensary” (Ufa) were analyzed. The groups were formed based on the detection of concomitant pathology (main, n=33) and its absence (control, n=34). To achieve the goal of the study, a comparative analysis of methods for detecting tuberculosis and clinical manifestations of tuberculosis was performed; prevalence of the process, detection of the fact of bacterial excretion and drug sensitivity from December 2020 to August 2021. 67 case histories of Mycobacterium tuberculosis (MBT) in patients of the studied groups were analyzed. Statistical data processing was performed using licensed software Statistica 6.0 when calculating two types of data: discrete and interval. To assess the chances of detecting the studied factor in both groups, the indicator (OR) was used to calculate the 95% confidence interval (CI). Interval indicators were studied by t-test for independent samples, with Livigne's correction.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECT PRODUCED BY IL-2 AND IL-15 ON THE PROLIFERATION OF T CELLS IN VITRO IN PATIENTS DIAGNOSED WITH BREAST CANCER","authors":"S. V. Timofeeva, S.Yu. Filippova, A. Sitkovskaya, I. A. Novikova, O.I. Kit, S.S. Mezentsev, L.N. Vashchenko, E. Kechedzhieva, I. Dashkova, T. V. Ausheva","doi":"10.18137/cardiometry.2023.29.conf.24","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.conf.24","url":null,"abstract":"Over the past decade, the use of adoptive immunotherapy has emerged as a promising approach to treatment of various malignancies, including breast cancer. Cytokines are involved in the development, differentiation and homeostasis of the T cells. Despite the similarities in signaling pathways, the γc cytokines shape the T cell responses differently: IL-2 plays a major role in the development and maintenance of the regulatory T cells, while IL15 stimulates the proliferation and cytotoxic functions of the CD8+ T cells and NK- cells that leads to an enhanced antitumor response. It is of interest to study the combined effect of these cytokines in an experiment.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139305066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SONODYNAMIC THERAPY (SDT) AND GENE THERAPY","authors":"T. Inui","doi":"10.18137/cardiometry.2023.29.conf.8","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.conf.8","url":null,"abstract":"One in Four Deaths in Japan Caused by Cancer. Cancer is the most common cause of death for Japanese people who are 40 and over, while suicide is the leading cause among young people.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139305603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HISTORY OF DEVELOPMENT OF ACTIVATION MAGNETIC THERAPY OF TUMORS AND MODERN WAVE TECHNOLOGIES. DEDICATED TO THE MEMORY OF E. B. KVAKINA AND THE 90TH ANNIVERSARY OF HER BIRTH","authors":"A. Shikhlyarova","doi":"10.18137/cardiometry.2023.29.conf.23","DOIUrl":"https://doi.org/10.18137/cardiometry.2023.29.conf.23","url":null,"abstract":"The 20th century was skeptical about magnetobiology. But the early experiments conducted by the American couple Barnothy, M. F., & Barnothy, J. M, who presented their data on the possibility of inhibiting the growth of tumors using strong magnetic fields, excited the world, and in the 60s last century, 3 international symposiums were held in Chicago, Rome, and Moscow to discuss that topical issue.","PeriodicalId":41726,"journal":{"name":"Cardiometry","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139293940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}