A. González-Suárez, E. Berjano, J. Guerra, L. Gerardo-Giorda
{"title":"A computational model of open-irrigated electrode for endocardial RF catheter ablation","authors":"A. González-Suárez, E. Berjano, J. Guerra, L. Gerardo-Giorda","doi":"10.1109/CIC.2015.7408589","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408589","url":null,"abstract":"Radiofrequency catheter ablation (RFCA) is an important curative treatment for cardiac arrhythmias. However, during RFCA thrombus formation can occur when the electrode-tissue interface temperature exceeds 80°C. Open-irrigated electrodes reduce the risk of such side-effect. No computational model of an open-irrigated electrode in endocardial RFCA accounting for both the saline irrigation flow and the blood motion in the cardiac chamber has been proposed yet. Our aim was to introduce the first computer model including both effects. The model has been validated against existing experimental results. Computational results showed that the surface lesion width and blood temperature are affected by the irrigation flow rate. Smaller surface lesion widths and blood temperatures are obtained with higher irrigation flow rate, while the lesion depth is not affected by changing the irrigation flow rate. Larger lesions are obtained when electrode is placed horizontally. Overall, the computational findings are in close agreement with previous experimental results.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130373396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Currie, R. Bond, P. Mccullagh, P. Black, D. Finlay
{"title":"VitalSimML - A well-formed data structure to Capture Patient Monitoring Scenarios to facilitate the training of nurses via computer-based simulation","authors":"Jonathan Currie, R. Bond, P. Mccullagh, P. Black, D. Finlay","doi":"10.1109/CIC.2015.7408676","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408676","url":null,"abstract":"Introduction: Patient monitoring is both a prevalent and critical nursing duty. Given that it requires the interpretation of vital signs and intricate decision-making, nurses could benefit from simulation-based training. Currently there is a lack of an open data structure for capturing training scenarios that can be used to augment simulation software and virtual reality applications. Methods: Twenty patient monitoring scenarios were analysed to identify the key common elements that are used to provide simulation. These elements aided the development of a data structure for storing training scenarios. Results: A well-formed eXtensible Markup Language (XML) data structure, currently titled VitalSimML, has been developed for capturing patient monitoring scenarios, which can be used for simulation-based training using dynamic intelligent software solutions. Conclusion: VitalSimML is the first attempt at a digital format for capturing patient monitoring scenarios.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115796749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Konstantinos N. Tzortzis, C. Roney, N. Qureshi, F. Ng, P. Lim, S. Sherwin, N. Peters, C. Cantwell
{"title":"Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation","authors":"Konstantinos N. Tzortzis, C. Roney, N. Qureshi, F. Ng, P. Lim, S. Sherwin, N. Peters, C. Cantwell","doi":"10.1109/CIC.2015.7408691","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408691","url":null,"abstract":"Left atrial anatomy and myocardial architecture are known to influence rotor initiation and maintenance. However, identifying their relative contribution clinically is challenging. The present study aims to investigate in silico the effect of left atrial geometry in isolation on rotor generation and evolution through the spatiotemporal tracking of phase singularities. After meandering for a short period of time, rotors are attracted to specific areas of the chamber where there is high curvature, primarily near the base of the left atrial appendage and the junctions of the pulmonary veins. This suggests that the left atrial anatomy could play a key role in the perpetuation of fibrillatory activity.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121045475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andjela Davidovic, Y. Coudière, T. Desplantez, C. Poignard
{"title":"Microscopic modelling of the non-linear gap junction channels","authors":"Andjela Davidovic, Y. Coudière, T. Desplantez, C. Poignard","doi":"10.1109/CIC.2015.7408677","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408677","url":null,"abstract":"The usual way to model the propagation of the action potential through the cardiac tissue is to assume passive diffusive intracellular and extracellular domains, and ion channel dynamics on the cells' membrane. Gap junctions (GJ) are localised clusters of gap junction channels (GJCs) that connects electrically adjacent cells. The importance of GJCs and their modifications in the signal propagation has been demonstrated in the experimental studies (e.g. Beauchamp et al 2012). But, in the current mathematical models the behaviour of the GJCs is either neglected or assumed to be passive, i.e the conductance of GJCs is taken as a steady constant. On the other hand, the experimental results, obtained by the dual-voltage clamp technique, show that GJCs are time and voltage dependent. Here we focus on describing ventricular GJCs made of connexin Cx43 and Cx45. We use the Hodgkin-Huxley formalism to describe GJC conductance via one gating variable. We incorporate the non-linear GJC voltage dependence into the microscopic model of the tissue as a new boundary condition on specific parts of the cells' membranes.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122849830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. E. Chávez, F. Atienza, N. Zemzemi, Y. Coudière, D. Álvarez
{"title":"Inverse localization of ischemia in a 3D realistic geometry: A level set approach","authors":"C. E. Chávez, F. Atienza, N. Zemzemi, Y. Coudière, D. Álvarez","doi":"10.1109/CIC.2015.7408628","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408628","url":null,"abstract":"The reconstruction of cardiac ischemic regions from body surface potential measurements (BSPMs) is usually performed at a single time instant which corresponds to the plateau or resting phase of the cardiac action potential. Using a different approach, we previously proposed a level set formulation that incorporates the knowledge of the cardiac excitation process in the inverse procedure, thus exploiting the spatio-temporal correlations contained in the BSPMs. In this study, we extend our inverse level-set formulation for the reconstruction of ischemic regions to 3D realistic geometries, and analyze its performance in different noisy scenarios. Our method is benchmarked against zero-order Tikhonov regularization. The inverse reconstruction of the ischemic region is evaluated using the correlation coefficient (CC), the sensitive error ratio (SN), and the specificity error ratio (SP). Our algorithm outperforms zero-order Tikhonov regularization, specially in highly noisy scenarios.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132558953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Bear, M. Potse, J. Duchâteau, N. Zemzemi, Y. Coudière, R. Dubois
{"title":"Accuracy of lead removal vs linear interpolation in non-invasive electrocardiographic imaging (ECGI)","authors":"L. Bear, M. Potse, J. Duchâteau, N. Zemzemi, Y. Coudière, R. Dubois","doi":"10.1109/CIC.2015.7411067","DOIUrl":"https://doi.org/10.1109/CIC.2015.7411067","url":null,"abstract":"This study examines the effect of missing body surface potentials on inverse solutions, and determines if linear interpolation can regain information lost. Using simulated and experimental data, electrograms (EGMs) were reconstructed after 1) removing and 2) interpolating `broken' signals. Results showed that torso potentials missing over the chest can reduce inverse reconstruction accuracy. Linear interpolation did not improve, and could further deteriorate reconstruction accuracy.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"135 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124207509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binbin Xu, S. Jacquir, S. Binczak, H. Yahia, R. Dubois
{"title":"Classification of cardiac arrhythmia in vitro based on multivariate complexity analysis","authors":"Binbin Xu, S. Jacquir, S. Binczak, H. Yahia, R. Dubois","doi":"10.1109/CIC.2015.7410995","DOIUrl":"https://doi.org/10.1109/CIC.2015.7410995","url":null,"abstract":"Background: The animal models (in vitro or in vivo) provide an excellent tool to study heart diseases, among them the arrhythmia remains one of the most active research subjects. Problems: However, the arrhythmia inducing or treating effects in cardiac culture often happened long after the initial applications or in some relatively short time windows. Human-assisted monitoring is time-consuming and less efficient to capture rapidly the events. Methods: Electrocardiological signals are features by repetitive or similar patterns reflecting their intrinsic dynamics. Analyzing these patterns is of considerable interest to monitor/evaluate these dynamics' changes. Aims: Find appropriate (complexity) index which allows monitoring and classifying the arrhythmic events during the real-time signal acquisition in vitro or in clinical applications.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124634086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Corentin Dallet, L. Bear, J. Duchâteau, M. Potse, N. Zemzemi, V. Meillet, Y. Coudière, R. Dubois
{"title":"Local conduction velocity mapping for electrocardiographic imaging","authors":"Corentin Dallet, L. Bear, J. Duchâteau, M. Potse, N. Zemzemi, V. Meillet, Y. Coudière, R. Dubois","doi":"10.1109/CIC.2015.7408627","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408627","url":null,"abstract":"Slow conduction is a well-known pro-arrhythmic feature for tachycardia and fibrillation. Cardiac conduction velocity (CV) mapping can be extremely helpful for investigating unusual activation patterns. Although methods have been developed to estimate velocity vector field, from ex-vivo preparations (e.g. from optical mapping recordings), the estimation from in-vivo electrograms (EGMs) remains challenging. This paper presents a new method specifically designed for EGMs reconstructed non-invasively from body surface potentials using electrocardiographic imaging (ECGi). The algorithm is based on cardiac activation maps and assumes either a linear or quadratic wavefront shape. The proposed methodology was performed on computed and experimental data for epicardial pacing on healthy tissue. The results were compared with reference velocity vector fields and evaluated by analyzing the errors of direction and speed. The outcomes indicate that a linear wavefront is the most suited for cardiac propagation in healthy tissue.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133492150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Zemzemi, C. Dobrzynski, L. Bear, M. Potse, Corentin Dallet, Y. Coudière, R. Dubois, J. Duchâteau
{"title":"Effect of the torso conductivity heterogeneities on the ECGI inverse problem solution","authors":"N. Zemzemi, C. Dobrzynski, L. Bear, M. Potse, Corentin Dallet, Y. Coudière, R. Dubois, J. Duchâteau","doi":"10.1109/CIC.2015.7408629","DOIUrl":"https://doi.org/10.1109/CIC.2015.7408629","url":null,"abstract":"The effect of torso conductivity heterogeneities on the electrocardiographic imaging (ECGI) inverse problem solution is still subject of debate. In this study we present a method to assess the effect of these heterogeneities. We use an anatomical model containing the heart the lungs the bones and the torso surfaces. We use the bidomain model and we solve it using finite element methods in order to generate in silico data taking into account the torso heterogeneities. We add different noise levels on the body surface potentials and we solve the inverse problem for both homogenous and heterogeneous torso conductivities. We analyse the reconstructed solution using the relative error and the correlation coefficient.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124526925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kania, R. Maniewski, R. Zaczek, M. Kobylecka, G. Opolski, L. Królicki
{"title":"Exercise induced depolarization changes in BSPMs for assessment of ischemic heart disease","authors":"M. Kania, R. Maniewski, R. Zaczek, M. Kobylecka, G. Opolski, L. Królicki","doi":"10.1109/CIC.2015.7411068","DOIUrl":"https://doi.org/10.1109/CIC.2015.7411068","url":null,"abstract":"We studied the effect of exercise-induced ischemia on high-resolution body surface potential maps in the depolarization interval. In particular our aim was to evaluate the effectiveness of selected nine ECG parameters in diagnostics of ischemic heart disease (IHD). The study group consisted of 123 subjects. The distributions of ECG signals averaged in time at rest and at peak exercise were compared. It was observed that for patients with IHD, averaged decreases of QRS amplitude at peak exercise were higher than in the control group and in the group of patients without IHD. IHD was associated also with enlargement of the area on the thorax surface where the decrease in the amplitude and increase in shape changes of the QRS complex were observed. The most effective parameters for the separation of patients with IHD were quantifiers of QRS shape changes. The use of an optimized ECG electrode layout improves the diagnostic value of QRS morphology descriptors.","PeriodicalId":414802,"journal":{"name":"2015 Computing in Cardiology Conference (CinC)","volume":"217 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121856761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}