Uroonkoloji Bulteni-Bulletin of Urooncology最新文献_第2页

Metastasis Targeted Therapies in Renal Cell Cancer 肾细胞癌转移靶向治疗

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/uob.962

K. Narter, B. Özveren

引用次数: 0

A Rare Side Effect of Intravesical Bacillus Calmette-Guérin Therapy: Reactive Arthritis 膀胱内卡介苗-谷氨酰胺治疗的罕见副作用:反应性关节炎

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/UOB.915

Bahattin Kizilgok, V. Izol, E. Erken, M. Tansug

引用次数: 1

Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer 前列腺癌包膜下切除术与全睾丸切除术的比较

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/uob.925

T. N. Yıkılmaz, E. Öztürk, N. Hamidi, H. Başar

{"title":"Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer","authors":"T. N. Yıkılmaz, E. Öztürk, N. Hamidi, H. Başar","doi":"10.4274/uob.925","DOIUrl":"https://doi.org/10.4274/uob.925","url":null,"abstract":"Ad dress for Cor res pon den ce: Taha Numan Yıkılmaz MD, University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Clinic of Urology, Ankara, Turkey Phone: +90 312 336 09 09 E-mail: numanyikilmaz@gmail.com ORCID-ID: orcid.org/0000-0001-8410-2474 Re cei ved: 02.10.2017 Ac cep ted: 13.12.2017 Objective: We aimed to compare the oncologic and functional outcomes of patients who underwent subcapsular or total orchiectomy for surgical castration in prostate cancer. Materials and Methods: We studied 65 patients who underwent total or subcapsular orchiectomy with a diagnosis of prostate cancer between April 2014 and May 2017. At postoperative 3-month follow-up, prostate specific antigen (PSA) and total testosterone levels were measured and patients were asked about their psychological status due to organ loss. Results were compared between the groups. Results: Sixty-five patients were evaluable: 23 had subcapsular and 42 had total orchiectomy. The mean age of the cases was 71.4 (60-83) years, the mean PSA level was 45.4 ng/dL (4-3800 ng/dL), and 41 cases had metastatic foci. There was no significant difference between the complication rates of the groups, but duration of the operation was significantly shorter in the subcapsular orchiectomy group. The two groups had similar mean PSA and testosterone levels at postoperative 3 months, but significantly more patients with total orchiectomy reported psychological problems due to organ loss. Conclusion: Subcapsular orchiectomy should be preferred for surgical castration because of the short duration of operation and the advantage of organ presence within the scrotal sac after surgery. In terms of oncologic outcomes, subcapsular orchiectomy shows no difference from total orchiectomy and is a safe alternative.","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70979235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Prostate and Bladder Metastases of Malignant Melanoma: Case Report 恶性黑色素瘤前列腺和膀胱转移1例报告

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/UOB.911

A. Guragac, S. Yılmaz, Z. Demirer, H. C. Irkılata, Y. Kibar

引用次数: 0

Gleason Score Correlation Between Prostate Biopsy and Radical Prostatectomy Specimens 前列腺活检与根治性前列腺切除术标本的Gleason评分相关性分析

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/UOB.921

E. Öztürk, T. N. Yıkılmaz

{"title":"Gleason Score Correlation Between Prostate Biopsy and Radical Prostatectomy Specimens","authors":"E. Öztürk, T. N. Yıkılmaz","doi":"10.4274/UOB.921","DOIUrl":"https://doi.org/10.4274/UOB.921","url":null,"abstract":"Objective: Prostate cancer is the most common malignancy in men and the second cause of cancer-related mortality. Prostate biopsy and the Gleason score guide treatment decisions in prostate cancer. Several studies have investigated the correlation between biopsy scores and radical prostatectomy specimen scores. We also evaluated the correlation of Gleason scores of these specimens in our patient series. Materials and Methods: We retrospectively reviewed the data of 468 men who were diagnosed with prostate cancer and underwent radical prostatectomy between 2008 and 2017. Patients’ age, prostate-specific antigen levels at diagnosis, and prostate biopsy and radical prostatectomy specimen Gleason scores were recorded. Upgrading and downgrading were defined as increase or decrease of Gleason score of radical prostate specimen compared to Gleason score of prostate biopsy. Results: A total of 442 men diagnosed with prostate cancer were included in the study. The mean age of the patients was 62.62±6.26 years (44-84 years) and mean prostate specific antigen level was 9.01±6.84 ng/mL (1.09-49 ng/mL). Prostate biopsy Gleason score was <7 in 335 (75.8%) men, 7 in 80 (18.1%) men, and >7 in 27 (6.1%) men. Radical prostatectomy specimen Gleason score was <7 in 267 (60.4%) men, 7 in 113 (25.5%) men and >7 in 62 (14%) men. Gleason correlation was highest in the 240 patients (71.6%) with score <7 and was lowest in the 31 (38.75%) patients with score =7. Conclusion: This study demonstrated that the discordance rate between Gleason scores of prostate biopsy and radical prostatectomy specimens was 35.7%.","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70979140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Predictive Value of Hormonal Evaluation Before Prostate Needle Biopsy on Prostate Cancer T Stage and Prognosis 前列腺穿刺活检前激素评估对前列腺癌T期及预后的预测价值

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-04-02 DOI: 10.4274/UOB.942

S. Çelik, Ozan Bozkurt, H. Yıldız, O. Demir, B. Tuna, K. Yorukoglu, G. Aslan

引用次数: 0

Determination of Six Transmembrane Protein of Prostate 2 Gene Expression and Intracellular Localization in Prostate Cancer 前列腺癌组织中6种前列腺2跨膜蛋白基因表达及细胞内定位的测定

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2017-12-20 DOI: 10.4274/UOB.890

Bora Irer, O. Demir, A. Kefi, G. Aslan

引用次数: 0

Rare Benign and Uncertain Malignant Potential Tumors of Bladder: Review of the Literature 罕见的膀胱良性和不确定的潜在恶性肿瘤:文献综述

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2017-12-20 DOI: 10.4274/UOB.673

C. Yucel, M. Keskin

{"title":"Rare Benign and Uncertain Malignant Potential Tumors of Bladder: Review of the Literature","authors":"C. Yucel, M. Keskin","doi":"10.4274/UOB.673","DOIUrl":"https://doi.org/10.4274/UOB.673","url":null,"abstract":"Mesane kanserlerin %90’ından transizyonel hücreli (ürotelyal) karsinomlar sorumludur (1). Skuamöz hücreli karsinom ve adenokarsinoma daha az sıklıkla görülmektedir. Bu üç kanserin dışında kalan mesane tümörlerine nadiren rastlanmakla birlikte literatürde daha çok küçük hasta serilerine veya tek olguluk hasta sunumlarına rastlanmaktadır. Bu nadir tümörler az sıklıkla görülmelerine rağmen patolojik açıdan ürotelyal karsinomdan ayrımlarının yapılması gerekmektedir. Klinik seyirlerinin ve tedavi yaklaşımlarının ürotelyal karsinomdan farklılık göstermesi bu az rastlanan tümörleri ürolojik açıdan önemli hale getirmektedir. Bu tümörler klinik semptom olarak sıklıkla hematüri ile ortaya çıkarlar. İritatif ve obstrüktif semptomlarla da kendini gösteren tümörler vardır. Bu mesanede görülen nadir kitlelerden benign olanlar enflamatuvar miyofibroblastik tümör (İMT), postoperatif iğsi hücreli nodül (PSCN), sistitis sistika benzeri fibroepitelyal polip, leyomiyom, hemanjiyoma, nörofibroma, schwannoma, psödokarsinomatöz hiperplazi, soliter fibröz tümör ve inverted papillomadır. Malignite potansiyeli belirsiz olanlar ise paragangliyoma, granüler hücreli tümör ve perivasküler epiteloid hücreli tümördür. Bu derlemede mesanede nadir görülen benign ve malignite potansiyeli belirsiz tümörlerin belirgin klinikopatolojik özellikleri literatür gözden geçirilerek ortaya konulmuştur. Benign Tümörler","PeriodicalId":40816,"journal":{"name":"Uroonkoloji Bulteni-Bulletin of Urooncology","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2017-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70977514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Neutropenic Fever, Skin and Eye Toxicities Develops During Docetaxel Treatment in Metastatic Prostate Cancer: A Case Report 多西他赛治疗转移性前列腺癌期间出现中性粒细胞减少热、皮肤和眼睛毒性:1例报告

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2017-12-20 DOI: 10.4274/UOB.908

E. Şen, İrem Öner, O. Ata

引用次数: 0

Evaluation of the Relationship Between Duration of Smoking and Clinical and Pathologic Characteristics of Bladder Cancer at Diagnosis 评价吸烟时间与膀胱癌诊断时临床病理特征的关系

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Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2017-12-20 DOI: 10.4274/uob.870

Bora Irer, F. Dağ, G. Aslan

引用次数: 0