Nursing Reports最新文献

{"title":"The Relationship Between Changes in Physical Activity and Physical and Mental Health in Female Breast Cancer Survivors Undergoing Long-Term Activity Restrictions in Japan.","authors":"Naomi Tamai, Yasutaka Kimura, Ryuta Yoshizawa, Midori Kamizato","doi":"10.3390/nursrep15080279","DOIUrl":"10.3390/nursrep15080279","url":null,"abstract":"<p><p><b>Purpose</b>: Exercise is recommended for survivors of breast cancer to alleviate adverse reactions and reduce the psychological burden. In recent years, however, environmental factors (e.g., pandemics and climate change) have made it difficult to exercise outdoors. Therefore, this study focused on the COVID-19 pandemic in Japan and evaluated the relationship between changes in physical activity (PA) and mental and physical health in breast cancer survivors. <b>Methods</b>: A questionnaire survey was conducted among 345 outpatient female breast cancer survivors aged between 29 and 69 years. The questionnaire was based on the International Physical Activity Questionnaire, the Patient Health Questionnaire-9, the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire, and the Fear of COVID-19 Scale and included patient characteristics, changes in PA during pandemic restrictions, and needs for exercise support. The analysis categorized PA changes into two groups according to activity levels. The relationship between changes in PA and physical and mental health was evaluated using logistic regression analysis. <b>Results</b>: Patients with decreased PA accounted for 65.5% of the study population. Regardless of their activity level, these patients were aware of an increased susceptibility to COVID-19, showed a fear of the disease and a tendency for depression, and reported low life satisfaction and declined physical function. Of the patients who stopped exercising, 82.9% reported a decline in PA. Compared with those who had never exercised, those who stopped exercising saw their risk of depression increase by 15.6%. There was a high demand for personalized exercise support from healthcare professionals. <b>Conclusions</b>: Regardless of their activity level, decreasing PA during the pandemic decreased mental health and physical function in breast cancer survivors. There was a higher risk of depression among patients who stopped exercising. Because it is possible that similar situations may occur in the future, interventions by healthcare professionals must be considered in order to continue exercise.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informed Consent in Perinatal Care: Challenges and Best Practices in Obstetric and Midwifery-Led Models.","authors":"Eriketi Kokkosi, Sofoklis Stavros, Efthalia Moustakli, Saraswathi Vedam, Anastasios Potiris, Despoina Mavrogianni, Nikolaos Antonakopoulos, Periklis Panagopoulos, Peter Drakakis, Kleanthi Gourounti, Maria Iliadou, Angeliki Sarella","doi":"10.3390/nursrep15080273","DOIUrl":"10.3390/nursrep15080273","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Respectful maternity care involves privacy, dignity, and informed choice within the process of delivery as stipulated by the World Health Organization (WHO). Informed consent is a cornerstone of patient-centered care, representing not just a formal document, but an ongoing ethical and clinical process through which women are offered objective, understandable information to support autonomous, informed decision-making. <b>Methods:</b> This narrative review critically examines the literature on informed consent in maternity care, with particular attention to both obstetric-led and midwifery-led models of care. In addition to identifying institutional, cultural, and systemic obstacles to its successful implementation, the review examines the definition and application of informed consent in perinatal settings and evaluates its effects on women's autonomy and satisfaction with care. <b>Results:</b> Important conclusions emphasize that improving women's experiences and minimizing needless interventions require active decision-making participation, a positive provider-patient relationship, and ongoing support from medical professionals. However, significant gaps persist between legal mandates and actual practice due to provider attitudes, systemic constraints, and sociocultural influences. Women's experiences of consent can be more effectively understood through the use of instruments such as the Mothers' Respect (MOR) Index and the Mothers' Autonomy in Decision Making (MADM) Scale. <b>Conclusions:</b> To promote genuinely informed and considerate maternity care, this review emphasizes the necessity of legislative reform and improved provider education in order to close the gap between policy and practice.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12388696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Communication and Non-Technical Skills in Intermediate Care Nurses Through Ultra-Realistic Clinical Simulation: A Cross-Sectional Study.","authors":"Mireia Adell-Lleixà, Francesc Riba-Porquet, Laia Grau-Castell, Lidia Sarrió-Colás, Marta Ginovart-Prieto, Elisa Mulet-Aloras, Silvia Reverté-Villarroya","doi":"10.3390/nursrep15080272","DOIUrl":"10.3390/nursrep15080272","url":null,"abstract":"<p><p><b>Background</b>: Intermediate care units face growing complexity due to aging populations and chronic illnesses. Non-technical skills such as empathy and communication are crucial for quality care. We aimed to examine the relationship between communication skills, self-efficacy, and sense of coherence among intermediate care nurses. <b>Methods</b>: We conducted an observational, cross-sectional study with 60 intermediate care nurses from three units in a Catalan hospital, Spain. Participants engaged in high-fidelity simulation using geriatric end-of-life scenarios with an ultra-realistic manikin representing a geriatric patient at the end of life. NTSs were measured using validated tools: the Health Professionals Communication Skills Scale (HP-CSS), the General Self-Efficacy Scale, and the Sense of Coherence Questionnaire (OLQ-13). Sessions followed INACSL standards, including prebriefing, simulation, and debriefing phases. <b>Results</b>: Post-simulation outcomes revealed significant gains in interpersonal competencies, with men reporting higher assertiveness (<i>p</i> = 0.015) and greater satisfaction with both the simulation experience (<i>p</i> = 0.003) and the instructor (<i>p</i> = 0.008), underscoring gender-related perceptions in immersive training. <b>Conclusions</b>: Ultra-realistic clinical simulation is effective in enhancing NTS among intermediate care nurses, contributing to improved care quality and clearer professional profiles in geriatric nursing.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parents as First Responders: Experiences of Emergency Care in Children with Nemaline Myopathy: A Qualitative Study.","authors":"Raúl Merchán Arjona, Juan Francisco Velarde-García, Enrique Pacheco Del Cerro, Alfonso Meneses Monroy","doi":"10.3390/nursrep15080271","DOIUrl":"10.3390/nursrep15080271","url":null,"abstract":"<p><p><b>Background</b>: Nemaline myopathy is a rare congenital neuromuscular disease associated with progressive weakness and frequent respiratory complications. In emergency situations, families often serve as the first and only responders. The aim of this study is to explore how parents in Spain care for children with nemaline myopathy during emergency situations, focusing on the clinical responses performed at home and the organizational challenges encountered when interacting with healthcare systems. <b>Methods:</b> A qualitative phenomenological study was conducted with 17 parents from 10 families belonging to the Asociación Yo Nemalínica. Semi-structured interviews were performed via video calls, transcribed verbatim, and analyzed using Giorgi's descriptive method and ATLAS.ti software (version 24). Methodological rigor was ensured through triangulation, reflexivity, and member validation. <b>Results:</b> Four themes were identified. First, families were described as acting under extreme pressure and in isolation during acute home emergencies, often providing cardiopulmonary resuscitation and respiratory support without professional backup. Second, families managed ambiguous signs of deterioration using clinical judgment and home monitoring tools, often preventing fatal outcomes. Third, parents frequently assumed guiding roles in emergency departments due to a lack of clinician familiarity with the disease, leading to delays or errors. Finally, the transition to the Pediatric Intensive Care Unit was marked by emotional distress and rapid decision-making, with families often participating in critical choices about invasive procedures. These findings underscore the complex, multidisciplinary nature of caregiving. <b>Conclusions:</b> Parents play an active clinical role during emergencies and episodes of deterioration. Their lived experience should be formally integrated into emergency protocols and the continuity of care strategies to improve safety and outcomes.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Advance Care Planning into End-of-Life Education: Nursing Students' Reflections on Advance Health Care Directive and Five Wishes Assignments.","authors":"Therese Doan, Sumiyo Brennan","doi":"10.3390/nursrep15080270","DOIUrl":"10.3390/nursrep15080270","url":null,"abstract":"<p><p><b>Background/Objectives</b>: End-of-life care is a vital part of nursing education that has been overlooked until recent years. Advance care planning should be incorporated into the prelicensure nursing curriculum to build student nurses' confidence in aiding patients and families with their preferred future care plans. Advance care planning tools, such as the Advance Health Care Directive (AHCD) and Five Wishes, provide experiential learning opportunities that bridge theoretical knowledge with real-world patient advocacy. In this study, students were asked to complete either the AHCD or Five Wishes document as though planning for their own end-of-life care, encouraging personal reflection and professional insight. Embedding these assignments into nursing education strengthens students' confidence in facilitating end-of-life discussions. This study applied Kolb's experiential learning theory, including concrete experience, reflective observation, abstract conceptualization, and active experimentation, to explore student nurses' perspectives on the Advance Health Care Directive and Five Wishes assignments, as well as their understanding of end-of-life care. <b>Methods</b>: This study used an exploratory-descriptive qualitative design featuring one open-ended question to collect students' views on the assignments. <b>Results</b>: The final sample comprised 67 prelicensure student nurses from Bachelor of Science and Entry-Level Master's programs. The Advance Health Care Directive and/or Five Wishes assignment enhanced students' understanding of end-of-life decision-making. <b>Conclusions</b>: It is essential to complete the assignment and immerse oneself in an end-of-life situation to grasp patients' perspectives and concerns regarding when to engage in difficult conversations with their patients.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences, Beliefs, and Values of Patients with Chronic Pain Who Attended a Nurse-Led Program: A Descriptive Phenomenological Qualitative Study.","authors":"Jose Manuel Jimenez Martin, Angelines Morales Fernandez, Manuel Vergara Romero, Jose Miguel Morales Asencio","doi":"10.3390/nursrep15080269","DOIUrl":"10.3390/nursrep15080269","url":null,"abstract":"<p><p><b>Aim:</b> To explore the experiences, beliefs, and values of patients who participated in a two-arm randomized clinical trial assessing a nurse-led intervention program for chronic pain self-management, which demonstrated positive effects on pain reduction, depression, and anxiety, and on health-related quality of life 24 months after completion of the program. <b>Design:</b> Descriptive phenomenological qualitative study. <b>Methods:</b> Patients were recruited via telephone, informed about the study, and invited to participate in an individual interview at a place of their choice (hospital or home). All interviews were audiotaped, and an inductive thematic analysis was performed. <b>Results:</b> Seven interviews were carried out between both groups. Six emerging categories were found: effective relationship with the healthcare system, learning to live with pain, family and social support, behaviors regarding pain, resources for self-management, and concomitant determinants. <b>Conclusions:</b> Patients report key aspects that help us to understand the impact of this type of nurse-led group intervention: the intrinsic therapeutic effect of participating in the program itself, the ability to learn to live with pain, the importance of family and social support, the modification of pain-related behaviors, and the identification of resources for self-care. The findings highlight the need for gender-sensitive, individualized care approaches to chronic pain, addressing stigma and social context. Expanding community-based programs and supporting caregivers is essential, as is further research into gender roles, family dynamics, and work-related factors.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Preoperative Anxiety via Virtual Reality Technology: A Systematic Review.","authors":"Elina Christiana Alimonaki, Anastasia Bothou, Athina Diamanti, Anna Deltsidou, Styliani Paliatsiou, Grigorios Karampas, Giannoula Kyrkou","doi":"10.3390/nursrep15080268","DOIUrl":"10.3390/nursrep15080268","url":null,"abstract":"<p><p><b>Background:</b> Perioperative care is an integral part of the procedure of a surgical operation, with strictly defined rules. The need to upgrade and improve some individual long-term processes aims at optimal patient care and the provision of high-level health services. Therefore, preoperative care is drawn up with new data resulting from the evolution of technology to upgrade the procedures that need improvement. According to the international literature, a factor considered to be of major importance is high preoperative anxiety and its effects on the patient's postoperative course. High preoperative anxiety is postoperatively responsible for prolonged hospital stays, increased postoperative pain, decreased effect of anesthetic agents, increased amounts of analgesics, delayed healing of surgical wounds, and increased risk of infections. The use of Virtual Reality technology appears as a new method of managing preoperative anxiety. <b>Objective:</b> This study investigates the effect and effectiveness of Virtual Reality (VR) technology in managing preoperative anxiety in adult patients. <b>Methods:</b> A literature review was performed on 193 articles, published between 2017 and 2024, sourced from the scientific databases PubMed and Cochrane, as well as the trial registry ClinicalTrials, with a screening and exclusion process to meet the criterion of investigating VR technology's effectiveness in managing preoperative anxiety in adult patients. This systematic review was conducted under the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines. <b>Results:</b> Out of the 193 articles, 29 were selected. All articles examined the efficacy of VR in adult patients (≥18) undergoing various types of surgery. The studies represent a total of 2.354 participants from 15 countries. There are two types of VR applications: distraction therapy and patient education. From the studies, 14 (48%) used the distraction VR intervention, 14 (48%) used the training VR intervention, and 1 (4%) used both VR interventions, using a range of validated anxiety scales such as the STAI, VAS-A, APAIS, and HADS. Among the 29 studies reviewed, 25 (86%) demonstrated statistically significant reductions in preoperative anxiety levels following the implementation of VR interventions. VR technology appears to manage preoperative anxiety effectively. It is a non-invasive and non-pharmacological intervention with minimal side effects. <b>Conclusions:</b> Based on the review, the management of preoperative anxiety with VR technology shows good levels of effectiveness. Further investigation of the efficacy by more studies and randomized controlled trials, with a larger patient population, is recommended to establish and universally apply VR technology in the preoperative care process as an effective method of managing preoperative anxiety.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Flipped Classroom and Project-Based Learning Integration in Older Adult Health Education: A Mixed-Methods Study.","authors":"Fu-Chi Yang, Hsiao-Mei Chen","doi":"10.3390/nursrep15080267","DOIUrl":"10.3390/nursrep15080267","url":null,"abstract":"<p><p><b>Background:</b> As population aging accelerates, the demand for professionals in older adult care continues to rise. Traditional teaching methods often fail to improve students' willingness to serve older adults or foster teamwork. This study evaluated the effects of integrating a flipped classroom with project-based learning (PBL) and a hands-on clinical practicum into a health internship course. <b>Methods:</b> A mixed-methods design was adopted. Participants included 88 interdisciplinary university students enrolled in an 18-week, two-credit geriatric health internship course offered at a university in central Taiwan from August 2023 to July 2024. The course combined flipped classroom and PBL approaches, as well as clinical practicum activities. Data on willingness to serve older adults, teamwork skills, and learning outcomes were collected using structured questionnaires and analyzed with paired t-tests. <b>Results:</b> Significant improvements were found in willingness (from 68.93 to 73.15), teamwork (67.33 to 71.45), and learning outcomes (89.84 to 102.14) (<i>p</i> = 0.001). Qualitative findings further revealed increased empathy, improved teamwork, and enhanced ability to apply knowledge in real-world contexts. <b>Conclusions:</b> A teaching approach that integrates a flipped classroom, PBL, and a clinical practicum can effectively enhance students' competencies in older adult care. Future research should explore long-term and cross-cultural impacts.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Care to Reduce Suicide Risk in Cancer Patients: A Narrative Review of the Literature.","authors":"Álvaro Borrallo-Riego, María García-Mayo, Irene Gil-Ordóñez, Isabel Domínguez-Sánchez, María Dolores Guerra-Martín","doi":"10.3390/nursrep15080265","DOIUrl":"10.3390/nursrep15080265","url":null,"abstract":"<p><p><b>Background</b>: Cancer is one of the leading causes of morbidity and mortality worldwide and in Spain. Individuals with cancer are at a higher risk of suicide compared to the general population due to both general and disease-specific risk factors. <b>Objective</b>: To update knowledge on nursing care measures to address the risk of suicide in cancer patients. <b>Methods</b>: A narrative review was conducted by searching PubMed, WOS, Scopus, and CINAHL during February and March 2025. The inclusion criteria comprised original qualitative, quantitative, and/or mixed-methods studies related to the topic of the review. <b>Results</b>: Of the 289 identified studies, 23 were selected. Twelve studies of cancer patients, ten studies of healthcare professionals, and one study of caregivers and survivors were included. Regarding suicide risk factors, eight studies addressed demographic aspects, fifteen socio-economic factors, twenty-one psycho-emotional factors, and seventeen physical factors. Key risk factors included male sex, advanced age, social isolation, lack of social support, hopelessness, and physical deterioration. Seventeen studies highlighted the need for continuous and comprehensive nursing care using validated tools for systematic assessment of suicide risk. Eight emphasised the importance of ongoing training in suicide prevention, which is essential for developing communication skills and improving therapeutic relationships. Five studies underscored the relevance of a holistic approach that addresses the physical, emotional, social, and spiritual dimensions of patient care. Six extended this approach to include family members and caregivers. <b>Conclusions</b>: Suicide risk in cancer patients is associated with multiple risk factors. Emotional support and a comprehensive, continuous nursing approach-based on systematic assessments, specialised training, and a holistic focus-are key to effective suicide prevention.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12388755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncovering the Professional Landscape of Clinical Research Nursing: A Scoping Review with Data Mining Approach.","authors":"Mattia Bozzetti, Monica Guberti, Alessio Lo Cascio, Daniele Privitera, Catia Genna, Silvia Rodelli, Laura Turchini, Valeria Amatucci, Luciana Nicola Giordano, Vincenzina Mora, Daniele Napolitano, Rosario Caruso","doi":"10.3390/nursrep15080266","DOIUrl":"10.3390/nursrep15080266","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Clinical Research Nurses (CRNs) have emerged as pivotal actors in the conduct, coordination, and oversight of clinical trials globally. Over the past three decades, the role of the CRN has evolved in response to the increasing complexity of research protocols, ethical standards, and regulatory frameworks. Originating as task-oriented support figures, CRNs have progressively assumed broader responsibilities that include patient advocacy, protocol integrity, ethical vigilance, and interprofessional coordination. By mapping the global literature on CRNs, this review will examine how their role has been defined, implemented, and evaluated over the past three decades. <b>Methods</b>: A scoping review was conducted using JBI methodology and PRISMA-ScR guidelines. The search covered the peer-reviewed and gray literature from 1990 to 2024 across major databases. Data analysis combined traditional extraction with topic modeling, Multiple Correspondence Analysis, and k-means clustering to identify key themes. <b>Results</b>: From the 128 included studies, four major themes emerged: clinical trial management, role perception and team integration, professional competencies and development, and systemic barriers. Despite formal competency frameworks, CRNs face inconsistencies in role recognition, unstable contracts, and limited career pathways. Emotional strain and professional isolation are recurrent. Over time, their functions have evolved from task execution to broader responsibilities, including advocacy and ethical oversight. However, no studies reported patient-level outcomes, revealing a critical gap in the evidence base. <b>Conclusions</b>: CRNs play a vital but undervalued role in clinical research. Persistent structural challenges hinder their development and visibility. Enhancing institutional support and generating outcome-based evidence are necessary steps toward fully integrating CRNs into research infrastructures.</p>","PeriodicalId":40753,"journal":{"name":"Nursing Reports","volume":"15 8","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12388699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}