{"title":"Solving the ECGI Problem with Known Locations of Scar Regions","authors":"M. M. Diallo, M. Potse, R. Dubois, Y. Coudière","doi":"10.22489/CinC.2020.237","DOIUrl":"https://doi.org/10.22489/CinC.2020.237","url":null,"abstract":"We propose a methodology to take into account the location of scars in ECGI problem. The method is to consider the whole body, including blood, heart and remaining volume as a conductor with an electric current source field localized in the heart. We identify the source best matching a given body surface potential map, by solving the classical quadratic optimization problem with a Tikhonov regularization term. The method behaves better than the MFS method in presence of a scar. The correlation coefficients of the activation times around the scar are improved up to 10% on the epicardium, and 7% on the endocardium, by adapting the Tikhonov regularization parameter and conductivity coefficient in the scar.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124515665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elements Read GUI: a Versatile Tool to Display and Analyse Electrophysiological Experimental Data","authors":"Eugenio Ricci, F. Cona, S. Severi","doi":"10.22489/CinC.2020.422","DOIUrl":"https://doi.org/10.22489/CinC.2020.422","url":null,"abstract":"In this work we developed a tool to load, display, analyse and export data coming from cellular electrophysiology experiments. This tool was realized for and thanks to Elements srl, which will distribute it as an open-source software. This will allow researchers to use this GUI to perform simple analyses on their data, but also to modify it (or to add code to it) in order to implement the functionalities they desire. The possibility of customization to the needs of every laboratory was one of the main goals of our work. This is the reason why the tool was developed in MATLAB (version 2019b) using only the Home license, without the requirement of additional toolboxes. The analyses that can be performed include: I/V and G/V graphs, histograms and power spectral densities (Welch's method). Furthermore, fittings (linear, exponential, Gaussian, Boltzmann's curve) can be performed on both raw data and data coming from the analyses. Finally, it is possible to export the original data, the data of the analyses and the fitting parameters in a .mat file, thus allowing further and more complex analyses in MATLAB.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124554827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanshuang Xie, Huaiyu Zhu, Ji Zhao, Yisheng Zhao, Yun Pan
{"title":"Unreadable Segment Recognition of Single-lead Dynamic Electrocardiogram Signals Based on Morphological Algorithm and Random Forest Classifier","authors":"Hanshuang Xie, Huaiyu Zhu, Ji Zhao, Yisheng Zhao, Yun Pan","doi":"10.22489/CinC.2020.029","DOIUrl":"https://doi.org/10.22489/CinC.2020.029","url":null,"abstract":"Recognizing unreadable electrocardiogram (ECG) signals could reduce the error rate of automatic software analysis and improve the interpretation efficiency of doctors, especially for single-lead dynamic ECGs. In this paper, we propose an unreadable ECG segment recognition method based on morphological algorithm and random forest classifier (RFC). The single-lead ECG signals are first filtered and normalized for morphological opening and closing operation, to generate detection sequences with more obvious QRS waves, since the large amplitudes introduced by motion interference could be suppressed during this procedure. Then features such as Shannon entropy and kurtosis are extracted and the RFC is used for unreadable segment classification. A total of 3354 readable segments and 2199 unreadable segments with a length of 4 seconds are obtained from 37 patients for method evaluation. The accuracy of our method (92.94 ± 0.93%) is significantly higher than that of the method without morphological algorithm (85.68 ± 1.30%). Moreover, we also used the “N” and “~” categories of the database from PhysioNet/CinC Challenge 2017 for further verification, and the accuracy of the proposed method (93.75 ± 0.69%) is significantly higher than that of the model without morphological processing (82.25 ± 1.06%) as well.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114610378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Armañac, D. Hernando, J. Lázaro, C. D. Haro, R. Magrans, L. Sarlabous, J. López-Aguilar, P. Laguna, E. Gil, L. Blanch, R. Bailón
{"title":"Baroreflex Sensitivity Evolution Before Weaning From Mechanical Ventilation","authors":"Pablo Armañac, D. Hernando, J. Lázaro, C. D. Haro, R. Magrans, L. Sarlabous, J. López-Aguilar, P. Laguna, E. Gil, L. Blanch, R. Bailón","doi":"10.22489/CinC.2020.235","DOIUrl":"https://doi.org/10.22489/CinC.2020.235","url":null,"abstract":"Weaning is the process of withdrawing mechanical ventilation at the Intensive Care Units. The problem is that around 20% of weaned patients were not actually ready for discontinuation. Studies suggest that vagal dysfunction is lower in patients successfully weaned. Therefore, the Baroreflex Sensitivity (BRS) and Heart Rate Variability (HRV) are estimated to see if they can provide additional information to improve the prediction of weaning outcomes. 9 successfully weaned patients (S-group) and 6 unsuccessfully weaned (F-group) were monitored in the last hour prior to the Spontaneous Breathing Trial. The BRS is estimated through spectral analysis, to obtain the a parameter in the low and high frequency bands, and through the capacity, C, estimated by the Bivariate Phase Rectified Signal Average (BPRSA) method. The current clinic parameters of weaning readiness do not show statistical differences. However, the capacity to changes of the BRS, C, estimated via BPRSA, exhibits significant differences between the two groups. Negative values of C, and with higher absolute values, were obtained for the S-group. Temporal indices of HRV also show differences, but not significant. These results suggest that BRS should be further explored for predicting weaning outcomes.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116293945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiabo Chen, Tianlong Chen, Bin Xiao, Xiuli Bi, Yongchao Wang, Han Duan, Weisheng Li, Junhui Zhang, Xu Ma
{"title":"SE-ECGNet: Multi-scale SE-Net for Multi-lead ECG Data","authors":"Jiabo Chen, Tianlong Chen, Bin Xiao, Xiuli Bi, Yongchao Wang, Han Duan, Weisheng Li, Junhui Zhang, Xu Ma","doi":"10.22489/CinC.2020.085","DOIUrl":"https://doi.org/10.22489/CinC.2020.085","url":null,"abstract":"Cardiovascular disease is a life-threatening condition, and more than 20 million people die from heart disease. Therefore, developing an objective and efficient computer-aided tool for diagnosis of heart disease has become a promising research topic. In this paper, we design a multi-scale shared convolution kernel model. In this model, two paths are designed to extract the features of electrocardiogram(ECG). The two paths have different convolution kernel sizes, which are 3×1 and 5×1, respectively. Such multi-scale design enables the network to obtain different receptive fields and capture information at different scales, which significantly improves the classification effect. And squeeze-and-excitation networks (SE-Net) are added to every path of the model. The attention mechanism of SE-Net learns feature weights according to loss, which makes the effective feature maps have large weights and the ineffective or low-effect feature maps have small weights. Our team name is CQUPT_ECG. Our approach achieved a challenge validation score of 0.640, and full test score of 0.411, placing us 8 out of 41 in the official ranking.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"138 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116432365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffuse and Stringy Fibrosis in a Bilayer Interconnected Cable Model of the Left Atrium","authors":"Ariane Saliani, V. Jacquemet","doi":"10.22489/CinC.2020.450","DOIUrl":"https://doi.org/10.22489/CinC.2020.450","url":null,"abstract":"Interconnected cable models of cardiac tissue are known for their numerical stability and performance at high resolution, their handling of strong anisotropy and their interpretation as network of resistors. Building such as mesh is however not straightforward. We developed an approach for automatic construction of 3D bilayer interconnected cable models from left atrial geometry and epi- and endocardial fiber orientation fields. The model consisted of a series of longitudinal and transverse cables intertwined like fabric threads, with a spatial discretization of 100 µm. Diffuse fibrosis was introduced as random uncoupling of cell-to-cell longitudinal and transverse connections. Stringy fibrosis was intended to represent collagenous septa and was implemented as a random set of longitudinal lines of transverse uncoupling (along cables) with Poisson-distributed length. The range of possible uncoupling percentages was assessed by investigating the percolation limit. This modeling approach was tested by simulating activation maps in normal and fibrotic tissues.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124069570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Haddi, B. Ananou, Youssef Trardi, S. Delliaux, J. Deharo, M. Ouladsine
{"title":"Fusion of Multiple Univariate Data Analysis-based Detectors to Build a Specific Fingerprint of Atrial Fibrillation","authors":"Z. Haddi, B. Ananou, Youssef Trardi, S. Delliaux, J. Deharo, M. Ouladsine","doi":"10.22489/CinC.2020.449","DOIUrl":"https://doi.org/10.22489/CinC.2020.449","url":null,"abstract":"Automatic and fast atrial fibrillation (AF) diagnosis is still a major concern for the healthcare professional. Several algorithms based on univariate and multivariate analysis have been developed to detect AF. Although the published results do show satisfactory detection accuracy, computational complexity of such methods is still questionable. This study proposes an alternative way to diagnosis AF arrhythmia which is based on the combination of seven univariate data analysis-based detectors followed by a majority voting in order to build a digital fingerprint of AF. Four publicly-accessible sets of clinical data were used for AF assessment. The time series were segmented in 10 s RR interval window. The features of the four databases were merged in order to give rise huge variability and therefore to better characterize AF arrhythmia. Afterwards, a receiver operating characteristic curve analysis has been conducted to fix optimal thresholds for AF detection. Finally, the seven obtained detectors have been concatenated and then a majority rule was applied to yield a final decision on AF diagnosis. The results showed that this strategy performed better than some existing algorithms do, with 98.50% for sensitivity and 95.1 % specificity.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124461054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"False Alarm Reduction in Atrial Fibrillation Screening","authors":"Hesam Halvaei, E. Svennberg, L. Sörnmo, M. Stridh","doi":"10.22489/CinC.2020.255","DOIUrl":"https://doi.org/10.22489/CinC.2020.255","url":null,"abstract":"Early detection of AF is essential and emphasizes the significance of AF screening. However, AF detection in screening ECGs, usually recorded by handheld and portable devices, is limited because of their high susceptibility to noise. In this study, the feasibility of applying a machine learning-based quality control stage, inserted between the QRS detector and AF detector blocks, is investigated with the aim to improve AF detection. A convolutional neural network was trained to classify the detections into either true or false. False detections were excluded and an updated series of QRS complexes was fed to the AF detector. The results show that the convolutional neural network-based quality control reduces the number of false alarms by 24.8% at the cost of 1.9% decrease in sensitivity compared to AF detection without any quality control.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125698379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Natarajan, Yale Chang, S. Mariani, Asif Rahman, G. Boverman, S. Vij, J. Rubin
{"title":"A Wide and Deep Transformer Neural Network for 12-Lead ECG Classification","authors":"A. Natarajan, Yale Chang, S. Mariani, Asif Rahman, G. Boverman, S. Vij, J. Rubin","doi":"10.22489/CinC.2020.107","DOIUrl":"https://doi.org/10.22489/CinC.2020.107","url":null,"abstract":"Cardiac abnormalities are a leading cause of death and their early diagnosis are of importance for providing timely interventions. The goal of 2020 PhysioNetlCinC challenge was to develop algorithms to diagnose multiple cardiac abnormalities using 12-lead ECG data. In this work, we develop a wide and deep transformer neural network to classify each 12-lead ECG sequence into 27 cardiac abnormality classes. Our approach combines handcrafted ECG features, which were determined to be important by a random forest model, and discriminative feature representations that are automatically learned from a transformer neural network. Our entry to the 2020 Phys-ioN etlCinC challenge placed 1st out of 41 official ranking teams (team name = prna). Using the official generalized weighted accuracy metric for evaluation, we achieved a validation score of 0.587 and top score of 0.533 on the full held-out test set.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"130 15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126136388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charilaos A. Zisou, Andreas Sochopoulos, Konstantinos Kitsios
{"title":"Convolutional Recurrent Neural Network and LightGBM Ensemble Model for 12-lead ECG Classification","authors":"Charilaos A. Zisou, Andreas Sochopoulos, Konstantinos Kitsios","doi":"10.22489/CinC.2020.417","DOIUrl":"https://doi.org/10.22489/CinC.2020.417","url":null,"abstract":"Automatic abnormality detection of ECG signals is a challenging topic of great research and commercial interest. It can provide a cost-effective and accessible tool for early and accurate diagnosis, which increases the chances of successful treatment. In this study, an ensemble classifier that identifies 24 types of cardiac abnormalities is proposed, as part of the PhysioNet/Computing in Cardiology Challenge 2020. The ensemble model consists of a convolutional recurrent neural network that is able to automatically learn deep features, and LightGBM, a gradient boosting machine that relies on hand-engineered expert features. The individual models are combined using class-specific weights and thresholds, which are tuned by a genetic algorithm. Results from 5-fold cross validation on the full training set, report the Challenge metric of 0.593 that outperforms both individual models. On the full hidden test set, the proposed architecture by “AUTh Team” achieves a score of 0.281 with an official ranking of 13/41.","PeriodicalId":407282,"journal":{"name":"2020 Computing in Cardiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124604387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}