{"title":"[An effective tool, a shared commitment: INFO-SPD].","authors":"V J Baixauli Fernández","doi":"10.33620/FC.2173-9218.(2025).25","DOIUrl":"10.33620/FC.2173-9218.(2025).25","url":null,"abstract":"<p><p>In a context of aging, chronicity, and polymedication, Personalized Dosage Systems (PDS) are an effective tool for improving therapeutic adherence and patient safety. However, they remain little known and underutilized. To reverse this situation, SEFAC has launched the INFO-SPD project, which reinforces the role of community pharmacists as key agents in improving health outcomes. The initiative offers materials adapted for professionals and patients and promotes a collaborative and normalized approach.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"1-2"},"PeriodicalIF":0.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-07-08eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).24
D Reyes Estévez, A González Rodríguez, A Morcuende Campos, M E Córcoles Ferrándiz, E Merencio Naudin
{"title":"[Exploring the Connection Between Pain, Age, Sex, Quality of Life, Functional Capacity, And Sleep: An Analysis in Community Pharmacy].","authors":"D Reyes Estévez, A González Rodríguez, A Morcuende Campos, M E Córcoles Ferrándiz, E Merencio Naudin","doi":"10.33620/FC.2173-9218.(2025).24","DOIUrl":"10.33620/FC.2173-9218.(2025).24","url":null,"abstract":"<p><strong>Introduction: </strong>Pain has a significant impact on quality of life. Personalized care emerges as a key strategy in pain management. Objectives: To identify the characteristics of patients with acute or chronic pain who visit the community pharmacy (CP) and to analyze the relationships between these characteristics in order to support future research.</p><p><strong>Material and methods: </strong>A descriptive, observational, cross-sectional, multicenter study was conducted in patients experiencing pain who attended community pharmacies (CPs). The study took place from October 14 to 27, 2019, in 47 CPs across Spain. The variables analyzed included: pain intensity (VAS), type of pain based on duration and diagnosis, type of medication, quality of life (EuroQoL-5D questionnaire), functional capacity (Karnofsky Performance Status), sleep quality (Insomnia Severity Index - ISI), and satisfaction with treatment.</p><p><strong>Results: </strong>A total of 403 participants were included: 28% were men and 72% women; 39% were over 70 years old, 45% between 40-69 years, and 16% between 18-39 years. Acute pain was reported by 25% of subjects, and chronic pain by 75%; 90% had non-oncological pain. The mean values observed were: VAS 6.1; EuroQoL 8.3; Karnofsky 78.1; and ISI 9.7. The correlational analysis between VAS, EuroQoL-5D, Karnofsky, and ISI, performed using Spearman's correlation coefficient (SC), showed statistically significant correlations: VAS and EuroQoL (SC=0.47; p<0.001), VAS and EuroQoL pain dimension (SC=0.52; p<0.001), VAS and ISI (SC=0.33; p<0.001), and a negative correlation between VAS and Karnofsky (SC=-0.33; p<0.001).</p><p><strong>Conclusions: </strong>Correlations were identified between age and quality of life, as well as between sex and age with functional capacity. Finally, an association was observed between pain intensity (measured using the VAS scale) and indicators of quality of life, sleep quality, and functional capacity.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"89-119"},"PeriodicalIF":0.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-07-01eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).23
J García Soláns
{"title":"[Phenotypic Classification of Diabetes: A Personalized Approach for Pharmaceutical Practice].","authors":"J García Soláns","doi":"10.33620/FC.2173-9218.(2025).23","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).23","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes mellitus (DM) is a heterogeneous metabolic disease with multiple pathophysiological mechanisms. The traditional classification into type 1 diabetes (T1D) and type 2 diabetes (T2D) does not fully capture the diversity of clinical and metabolic profiles among patients. Recently, Ahlqvist et al. proposed a model based on five phenotypic subtypes, enabling a more precise stratification of the disease and a personalized therapeutic approach.</p><p><strong>Methods: </strong>Through cluster analysis in cohorts of diabetic patients, five subgroups were identified: Severe Autoimmune Diabetes (SAID), Severe Insulin Deficient Diabetes (SIDD), Severe Insulin Resistant Diabetes (SIRD), Mild Obesity-related Diabetes (MOD), and Mild Age-related Diabetes (MARD). These phenotypes differ in pathophysiology, disease progression, and treatment response.</p><p><strong>Results and discussion: </strong>Phenotypic stratification allows better prediction of microvascular and macrovascular complications, optimizes pharmacotherapy, and enhances personalized interventions. In community pharmacy, this classification could improve subtype identification, facilitate more precise therapeutic recommendations, and promote treatment adherence. However, its implementation faces challenges, such as limited access to key biomarkers.</p><p><strong>Conclusions: </strong>The phenotypic classification of DM represents a step toward personalized medicine. As key healthcare professionals in chronic disease management, community pharmacists can play a crucial role in its application, improving patient education and therapeutic monitoring to enhance clinical outcomes.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"76-89"},"PeriodicalIF":0.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-06-19eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).21
N Acuña Elvira
{"title":"[Multidisciplinary approach for a patient with morbid obesity and psychological issues led from the pharmacy office].","authors":"N Acuña Elvira","doi":"10.33620/FC.2173-9218.(2025).21","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).21","url":null,"abstract":"<p><strong>Abstract: </strong>A 58-year-old woman diagnosed with diabetes and hypercholesterolemia and undergoing treatment for breast cancer. Take metformin, rosuvastatin, and anastrozole. She goes to the community pharmacy to pick up a treatment for flatulence that has been prescribed to her in primary care. The prescribed medications are dispensed: Clebopride/Simeticone and paracetamol in addition to asking the pharmacy for a shower gel without detergent for back irritations. After 5 days of treatment, the patient returns requesting a more powerful analgesic since the pain has worsened.The patient was referred to the emergency department upon detection of an MRI of Necessity related to an untreated health problem. In the emergency department, he undergoes an ultrasound and intravenous analgesics that relieve the pain, diagnoses nephritic colic and prescribes metamizole and tramadol/paracetamol. The next day the patient goes to her primary care doctor and he tells her to continue with the prescribed treatment in the emergency room.The patient goes to the community pharmacy again requesting something for the rashes on her back since the gel does not calm her. The pharmacist makes a second referral to the doctor, with a written communication of suspicion of Herpes Zoster, the doctor accepts the intervention and changes the treatment by putting Valacyclovir, paracetamol/codeine and capsaicin cream. The patient returns to the pharmacy reporting that the doctor was surprised that it was a pharmacist who gave the correct diagnosis.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"66-68"},"PeriodicalIF":0.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-06-18eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).19
S Borja Ripoll, F Mocholí Belenguer, V Traver Salcedo
{"title":"[Pharmaceutical interventions in the new medicine service].","authors":"S Borja Ripoll, F Mocholí Belenguer, V Traver Salcedo","doi":"10.33620/FC.2173-9218.(2025).19","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).19","url":null,"abstract":"<p><strong>Abstract: </strong>It is possible that traffic accidents caused by medication use are among the most underestimated compared with other types of accidents.This issue stems from human factors that affect driving even before it begins, increasing the likelihood of accidents. Therefore, it is a predictable and avoidable factor.In this context, it is essential to gain a deeper understanding of the medications that pose the greatest risks and how they influence driving.To do this, we will study the groups of drugs marketed in the European Union that can affect driving, analyzing the DRUID classification of medicines to determine which group of drugs can have the most influence on driving.To this end, the DRUID classification has been reviewed, the technical data sheets of medications marketed in Spain have been analyzed, focusing on the sections regarding \"Effects on driving\" and \"Adverse effects,\" and the frequency of these effects has been evaluated to identify the medications with the greatest impact.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"17-25"},"PeriodicalIF":0.6,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-06-16eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).18
S Nadal Domingo, D Domingo Tortajada
{"title":"[Multidisciplinary approach for a patient with morbid obesity and psychological issues led from the pharmacy office].","authors":"S Nadal Domingo, D Domingo Tortajada","doi":"10.33620/FC.2173-9218.(2025).18","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).18","url":null,"abstract":"<p><strong>Abstract: </strong>A 42-year-old patient with obesity and psychological problems comes to the Community Pharmacy seeking nutritional advice to lose weight, since in the last 4 months there has been an increase of 19 kilograms of body weight.From the CF we offer specific nutritional help and, in addition, we propose to make a comparison of the medication she is using in the current situation and compare it with the one she was using before the weight gain. The patient accepts and, indeed, we observe certain changes that may be causing the weight gain.Therefore, we refer the case to the Primary Care Physician providing information regarding changes in medication, latest medical tests and other indicators that could be contributing to the weight gain. Simultaneously, we establish dietary follow-up with one session per week to monitor her diet and eating habits.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"26-29"},"PeriodicalIF":0.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-05-20eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).16
Amparo Bonilla Guijarro, María Dolores Fernández Otero, Noelia Tejedor García, José Ma Ordóñez Iriarte, Antonio Aguilar Ros
{"title":"[Causes of Patient Referral by Community Pharmacists in Madrid: An Analysis of the Conexión Futuro Study].","authors":"Amparo Bonilla Guijarro, María Dolores Fernández Otero, Noelia Tejedor García, José Ma Ordóñez Iriarte, Antonio Aguilar Ros","doi":"10.33620/FC.2173-9218.(2025).16","DOIUrl":"10.33620/FC.2173-9218.(2025).16","url":null,"abstract":"<p><strong>Introduction: </strong>The high prevalence of problems related to invalid or erroneous prescriptions causes numerous patient referrals from community pharmacy, as well as problems related to patients' adherence to their treatments and underscores the importance of effective review and validation systems in pharmacies.</p><p><strong>Objective: </strong>To identify and quantify the causes of patient referral from community pharmacies to physicians.</p><p><strong>Methods: </strong>Observational, cross-sectional, non-interventional and analytical study. The possible causes of patient referral from community pharmacies were defined and these causes were quantified by means of an online questionnaire.</p><p><strong>Results: </strong>A total of 3530 referrals were recorded from 165 community pharmacists in 114 pharmacies. The most frequent cause of referral was lack of a valid prescription (57.7%). Health problems requiring a prescription (18.4%) and problems with the prescribed medication, such as shortages or incorrect dosage (17.2%) were also identified.The study highlights the importance of implementing Complementary Dispensing (CD) and Independent Dispensing (ID) to reduce referrals and improve adherence to treatment. Thirty-two percent of referrals could have been avoided through these professional pharmaceutical actions, reducing the pressure on primary care, specialized and emergency care centers, allowing pharmacists to adjust or advance prescriptions under consensus with physicians or to dispense certain drugs without prescription. The previously defined referrals were collected by means of a validated questionnaire.</p><p><strong>Conclusion: </strong>Expanding the competencies of community pharmacists would improve the efficiency of the health care system, reducing referrals and improving adherence to treatment.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"3-16"},"PeriodicalIF":0.6,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-05-19eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).20
N Amador-Fernández, E L Graham, ShI Benrimoj, E Pérez-Hoyos, V J Baixauli, V Colomer-Molina, O García-Agudo, V García-Cárdenas, M A Gastelurrutia, J Giner-Martínez, R Palomo-Llinares, R Sánchez-Tormo, F Martínez-Martínez
{"title":"[Pharmaceutical interventions in the new medicine service].","authors":"N Amador-Fernández, E L Graham, ShI Benrimoj, E Pérez-Hoyos, V J Baixauli, V Colomer-Molina, O García-Agudo, V García-Cárdenas, M A Gastelurrutia, J Giner-Martínez, R Palomo-Llinares, R Sánchez-Tormo, F Martínez-Martínez","doi":"10.33620/FC.2173-9218.(2025).20","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).20","url":null,"abstract":"<p><strong>Background: </strong>Community pharmacy has been promoted internationally for the management of minor ailments with positive results for patients and health care systems. This study evaluates the clinical impact and implementation of a minor ailment service in community pharmacies' daily practice.</p><p><strong>Methods: </strong>A pragmatic study with a hybrid effectiveness-implementation design was conducted throughout Spain between 2020-2023. Patients who visited community pharmacies to consult or request a medicine for a minor ailment were included. The intervention consisted of a protocol for the minor ailment service and specific protocols for each ailment agreed with general medical practitioners through the SEFAC eXPERT® IT platform and after community pharmacists' training. Patients were followed up 10 days after the consultation.</p><p><strong>Results: </strong>A total of 430 pharmacies registered 20,987 consultations. 85.2% (n=17,885) were consultations about minor ailments and 14.8% (n=3,102) were requests for specific medications. Minor ailments related to pain (18.7%, n=3,935) were the most frequently consulted. Pharmacists recommended pharmacological treatment to 81.3% (n=17,063) patients and referred 8.0% (n=1,682) patients to a general medical practitioner. 72.4% (n=15,192) of patients responded to follow-up with a symptom resolution of 9.0/10.0, a change in quality of life of +9.0 (0-100 scale) and a satisfaction with the service of 9.6/10.</p><p><strong>Conclusions: </strong>SIF proved to be both operational and effective, yielding beneficial health outcomes. Its implementation enabled the evaluation of a substantial number of consultations and highlighted the need to encourage the routine documentation of services in community pharmacy practice.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"17-25"},"PeriodicalIF":0.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farmaceuticos ComunitariosPub Date : 2025-05-19eCollection Date: 2025-07-15DOI: 10.33620/FC.2173-9218.(2025).17
D Barris Blundell, G Benítez Pacheco, M J Hidalgo Hidalgo, M A Mercado Cano
{"title":"[Pharmaceutical interventions in the new medicine service].","authors":"D Barris Blundell, G Benítez Pacheco, M J Hidalgo Hidalgo, M A Mercado Cano","doi":"10.33620/FC.2173-9218.(2025).17","DOIUrl":"https://doi.org/10.33620/FC.2173-9218.(2025).17","url":null,"abstract":"<p><strong>Objective: </strong>A study is presented whose main objective is to describe pharmaceutical interventions in the assistance service in the dispensing of newly prescribed medications in patients of two community pharmacies.</p><p><strong>Methodology: </strong>Descriptive observational study, carried out in two community pharmacies in the province of Malaga with patients who come for new medical prescriptions over 6 months (March 2022 - August 2022). Pharmaceutical interventions have been recorded, recording the following aspects: age, sex, new prescription, other medications, pharmaceutical intervention (posology-dose, indication), follow-up of the new medication. Regarding the follow-up of the new medication, the detection of a drug-related Problem (DRP) (possible adverse effects, interactions, lack adherence) and/or a Negative Outcome associated with Medication (NOM) has been recorded in the Dáder method intervention sheet.</p><p><strong>Results: </strong>251 records of new medication have been documented, which have totalled 258 new prescription medications. The average age of the patients was 58.6 years. The average number of medications used by the patients was 5.1 with a range between 1 and 15. In relation to the sex of the patients, 41.4% (n=104) were men and 58.6% (n=147) were women.The five therapeutic groups most studied have been: C10 Lipid-modifying agents (n=33), A10 Drugs used in diabetes (n=28), C09 Agents that act on the renin-angiotensin system (n=21), N06 Psychoanaleptics (n=19) and M01 Anti-inflammatory and antirheumatic products (n=13).A NOM was detected in 31.5% (n=79) of the patients, with non-quantitative safety problem being the most frequent (60.0% - n=48). 23 DRP of lack adherence have been documented.</p><p><strong>Conclusions: </strong>The development of this service represents an opportunity for the team's assistant pharmacists to participate in a Clinical Professional Pharmacy Services in a homogeneous and systematized way, with the consequent documentation of their interventions and with a more active involvement in the patients' health processes. The need for greater integration of the two community pharmacies in the health system is evident.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 3","pages":"17-25"},"PeriodicalIF":0.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Community pharmacy and global warming].","authors":"G Estrada Riolobos","doi":"10.33620/FC.2173-9218.(2025).15","DOIUrl":"10.33620/FC.2173-9218.(2025).15","url":null,"abstract":"<p><p>The acceleration of climate change due to human activities demands urgent action at all levels. In the healthcare sector, the use of inhalers with high global warming potential represents a significant source of emissions, further exacerbated by low recycling rates. The transition to lower-impact devices and improved waste management are priority actions. In this context, community pharmacists play a key role-not only in optimizing inhalation therapy and educating patients, but also in reducing the associated carbon footprint-thus promoting a more sustainable healthcare practice.</p>","PeriodicalId":40648,"journal":{"name":"Farmaceuticos Comunitarios","volume":"17 2","pages":"1-2"},"PeriodicalIF":0.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}