Online Türk Sağlık Bilimleri Dergisi最新文献_第2页

Broadening the Discourse on Death Anxiety: Unexplored Dimensions and Holistic Perspectives 拓宽关于死亡焦虑的讨论：未探索的层面和整体视角

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1401412

Serdar Özdemir

引用次数: 0

Sporcuların Sağlıklı Yaşam Biçimi Davranışlarının İncelenmesi 运动员健康生活方式调查

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1389348

İbrahim Can Cengi̇zoğlu, Burçak Keskin, Sema Arslan Kabasakal

引用次数: 1

Construction of Mesenchymal Stem Cell-Derived Artificial Human Urinary Bladder: A Preliminary Study 构建间充质干细胞衍生的人造人膀胱：初步研究

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1402217

Seçil Erden Tayhan, A. Şendemir, Erol Mi̇r, İsmet DELİLOĞLU GÜRHAN

{"title":"Construction of Mesenchymal Stem Cell-Derived Artificial Human Urinary Bladder: A Preliminary Study","authors":"Seçil Erden Tayhan, A. Şendemir, Erol Mi̇r, İsmet DELİLOĞLU GÜRHAN","doi":"10.26453/otjhs.1402217","DOIUrl":"https://doi.org/10.26453/otjhs.1402217","url":null,"abstract":"Objective: The present study aimed to obtain the required cells and select a suitable scaffold material for constructing an artificial bladder using the tissue engineering approach. \u0000Materials and methods: The convenience of obtaining human adipose tissue-derived stem cells (hADMSCs) was used in this study. It was attempted to differentiate these cells into smooth muscle cells (SMC), which are present along the wall of the bladder. Urothelial cells were enzymatically isolated from tissue biopsies. Synthetic (poly-lactide co-glycolic acid, PLGA) and natural (chitosan) polymers were used in scaffold fabrication using a tissue engineering approach. \u0000Results: In the cellular experiments, urothelial cells couldn’t be cultured in polystyrene culture vessels in vitro and required a support material to maintain viability. Better results were obtained with the feeder layer. The hADMSCs exhibited the expected morphological changes in the serum-rich medium content in the SMC differentiation experiments. Chitosan, biocompatible and biodegradable, was mixed with PLGA as an alternative scaffold combination. \u0000Conclusion: This study indicated that hADMSCs-derived smooth muscle cells and biopsy-isolated urothelial cells cultured on hybrid chitosan–PLGA scaffolds with appropriate physical properties could serve as a suitable model for tissue-engineered artificial bladder construction.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140253489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reason for Discontinuing the Drug in Patients Using Statins 使用他汀类药物的患者停药的原因

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1398594

Sefa Tatar, İrem Oktay, Yunus Emre Yavuz, Yakup Alsancak, Ahmet Lütfü Sertdemir, Mustafa Çeli̇k

引用次数: 0

Yenidoğanlarda Uzamış Sarılıkta İdrar Yolu Enfeksiyonunun Sıklığı ve Rolü 尿路感染在新生儿长期黄疸中的发生率和作用

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1352277

Eray Tunce, Salih Demirhan, Rabia Gönül Sezer Yamanel

{"title":"Yenidoğanlarda Uzamış Sarılıkta İdrar Yolu Enfeksiyonunun Sıklığı ve Rolü","authors":"Eray Tunce, Salih Demirhan, Rabia Gönül Sezer Yamanel","doi":"10.26453/otjhs.1352277","DOIUrl":"https://doi.org/10.26453/otjhs.1352277","url":null,"abstract":"Objective: The study aims to investigate the frequency and role of urinary tract infection (UTI) in prolonged jaundice in preterm and term neonates. \u0000Materials and Methods: This retrospective study occurred at Zeynep Kamil Maternity and Children's Hospital in Istanbul between January 2014 and April 2018. The study involved 391 neonates who presented to our outpatient clinics with prolonged jaundice. UTI was defined as urine culture growth of at least 10.000 colony-forming units per millilitre (CFU/ml) in samples obtained via urethral catheterization. Birth weight, sex, gestational age, chronological age, laboratory results, hospital courses of patients, ultrasound findings and phototherapy history were recorded. \u0000Results: UTI frequency was found to be 2.8% in 391 neonates with prolonged jaundice. Nine of them were male (81.8%), and 2 were female (18.2%). Eight patients with UTI (72.7%) were term and 3 (29.3%) were preterm. History of phototherapy, presence of leukocyturia or nitrituria, white blood cell count, and thrombocyte counts were significantly higher in the UTI group. \u0000Conclusion: Prolonged jaundice may be the first sign of UTI in neonates. Routine urine culture in neonates with prolonged jaundice may be useful, especially in those with a history of phototherapy and high white blood cell and thrombocyte counts.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"135 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140251366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laurus nobilis Esansiyel Yağının Sıçanlarda İndometasin Kaynaklı Mide Ülserinin Azaltılmasında Potansiyel Rolü 月桂精油在减少吲哚美辛诱发大鼠胃溃疡中的潜在作用

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2024-03-11 DOI: 10.26453/otjhs.1417755

Hilal Üstündağ, Necip Gökhan Taş, Nezahat Kurt, Gizem Issi̇n, Ferdane DANIŞMAN KALINDEMİRTAŞ, Selcan Karakuş

{"title":"Laurus nobilis Esansiyel Yağının Sıçanlarda İndometasin Kaynaklı Mide Ülserinin Azaltılmasında Potansiyel Rolü","authors":"Hilal Üstündağ, Necip Gökhan Taş, Nezahat Kurt, Gizem Issi̇n, Ferdane DANIŞMAN KALINDEMİRTAŞ, Selcan Karakuş","doi":"10.26453/otjhs.1417755","DOIUrl":"https://doi.org/10.26453/otjhs.1417755","url":null,"abstract":"Objective: This study aimed to investigate the gastroprotective effects of Laurus nobilis leaves essential oil (LANO) against indomethacin (INDO)-induced gastric ulcers in rats. \u0000Materials and Methods: In this study, an indomethacin-induced gastric ulcer model was employed. 30 Sprague-Dawley rats were divided into five groups (n=6): Control, LANO, INDO, INDO with famotidine (FAM), and INDO with LANO. Indomethacin (25 mg/kg) induced ulcers, while LANO and FAM were administered by oral gavage at 200 mg/kg and 40 mg/kg, respectively. Gastric tissues underwent histopathological examination for ulceration, and biochemical assays measured total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and nitric oxide (NO) levels. \u0000Results: Compared to the INDO group, treatment with LANO significantly decreased the number of gastric ulcer foci. Biochemically, LANO moderated TOS and OSI levels and preserved TAS, indicating reduced oxidative stress. Additionally, LANO appeared to stabilize NO levels. These biochemical findings were corroborated by histopathological examination. \u0000Conclusions: The study's results indicate that LANO may be beneficial in protecting against NSAID-induced gastric damage. LANO's observed modulation of oxidative stress markers and NO levels suggests its potential role in managing gastric ulcers.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"104 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140251637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Jinekolojik Kanser veya Meme Kanserli Kadınların COVID-19 Pandemisi Sırasında Sağlık Bakımı Arama Davranışı, Psikososyal Belirtileri ve Sıkıntı Düzeylerinin Belirlenmesi 确定 COVID-19 大流行期间患有妇科癌症或乳腺癌的妇女的就医行为、社会心理症状和痛苦程度

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2023-12-13 DOI: 10.26453/otjhs.1233311

Sultan ÖZKAN ŞAT, Sevil ÇİÇEK ÖZDEMİR, Şengül YAMAN SÖZBİR, Ayten ŞENTÜRK ERENEL

{"title":"Jinekolojik Kanser veya Meme Kanserli Kadınların COVID-19 Pandemisi Sırasında Sağlık Bakımı Arama Davranışı, Psikososyal Belirtileri ve Sıkıntı Düzeylerinin Belirlenmesi","authors":"Sultan ÖZKAN ŞAT, Sevil ÇİÇEK ÖZDEMİR, Şengül YAMAN SÖZBİR, Ayten ŞENTÜRK ERENEL","doi":"10.26453/otjhs.1233311","DOIUrl":"https://doi.org/10.26453/otjhs.1233311","url":null,"abstract":"Objective: The study was conducted to determine the health-seeking behaviors, psychosocial symptoms and distress levels and related factors of women diagnosed with gynecological or breast cancer during the pandemic period.\u0000Materials and Methods: This descriptive, cross-sectional study was completed with a total of 109 women who had ovary, endometrium, cervix, vagina, vulva, or breast cancer. The study was conducted between October and December 2020, and data were collected online using an information form, Distress Thermometer and The Brief Symptom Inventory.\u0000Results: There was a decrease in the frequency of going to the hospital for diagnosis (54.8%), treatment (32.3%), and rehabilitation (58%) services during the COVID-19 pandemic process. Our study results indicated that 89% of women experienced distress, according to Distress Thermometer. The mean Brief Symptom Inventory scores were found to be statistically significantly higher in women who stated that they experienced distress, whose chemotherapy treatment was postponed, and who obtained more information from the Internet during this period.\u0000Conclusions: This study highlighted the pandemic’s impact on healthcare-seeking behaviors and distress experiences of women with gynecological or breast cancer. Our results indicate a restriction on receiving health services during this period in women. Also, our results showed that most women experienced distress.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"47 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138976918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examination of Perception of Nursing Care and Quality of Recovery in Surgical Patients According to Some Variables 根据一些变量研究外科患者对护理服务的感知和康复质量

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2023-12-13 DOI: 10.26453/otjhs.1288053

Pınar Ongün, Ayşe Karadaş

{"title":"Examination of Perception of Nursing Care and Quality of Recovery in Surgical Patients According to Some Variables","authors":"Pınar Ongün, Ayşe Karadaş","doi":"10.26453/otjhs.1288053","DOIUrl":"https://doi.org/10.26453/otjhs.1288053","url":null,"abstract":"Objective: The study aims to determine the relationship between the quality of care perception and healing quality levels of surgical patients and to determine the differences according to their characteristics.\u0000Materials and Methods: The descriptive cross-sectional study was carried out on 237 patients treated in the surgical clinics of a university hospital from December 2021 to May 2022. Data were collected using a descriptive information form, the Patient's Perception of Nursing Care Scale, and the Quality of Recovery-40 Scale.\u0000Results: The mean total score of the Patient's Perception of Nursing Care Scale was 71.45±9.81, and the mean total score of the Quality of Recovery-40 Scale was 106±15.95. The mean score of the physical independence sub-dimension of the Quality of Recovery-40 Scale was the highest (21.14±5.73), and the mean score of the pain sub-dimension was the lowest (9.32±3.57). There was statistically significant relationship between gender, having a companion, and Patient's Perception of Nursing Care Scale and between having a chronic disease and the Quality of Recovery-40 Scale. \u0000Conclusion: It was found that the level of patient's perception of nursing care was high, the level of recovery quality was below average, and there was no relationship between the level of perception of nursing care.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"12 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurochemical Effects of the Adipokinetic Hormone/Red Pigment Concentrating Hormone Family of Peptides in MK-801-Induced Schizophrenia Rat Model 在 MK-801 诱导的精神分裂症大鼠模型中脂肪动情激素/红色素浓缩激素家族肽的神经化学效应

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2023-12-13 DOI: 10.26453/otjhs.1374368

Şeyma Nur BAŞARIR BOZKURT, O. Mutlu, Daniel BERMEJO RODRİGUEZ, David Kacer, P. Tanyeri, Pınar Cobantürk, Karel Vales

{"title":"Neurochemical Effects of the Adipokinetic Hormone/Red Pigment Concentrating Hormone Family of Peptides in MK-801-Induced Schizophrenia Rat Model","authors":"Şeyma Nur BAŞARIR BOZKURT, O. Mutlu, Daniel BERMEJO RODRİGUEZ, David Kacer, P. Tanyeri, Pınar Cobantürk, Karel Vales","doi":"10.26453/otjhs.1374368","DOIUrl":"https://doi.org/10.26453/otjhs.1374368","url":null,"abstract":"Objective: Adipokinetic hormone (AKH) plays a role in sugar and lipid metabolism in insects. Previous studies of AKH showed memory improvements in a schizophrenia rat model that displayed memory impairment and reduced depression in a rat olfactory bulbectomy model. In this study, we investigated the effects of the adipokinetic hormone/red pigment-concentrating hormone (AKH/RPCH) family of peptides on brain neurotransmitter levels and brain neurochemistry in a schizophrenia rat model. \u0000Materials and Methods: We administered AKH/RPCH peptides for 4 days sub-chronically, both in naive rats and also in the MK-801-induced schizophrenia rat model. Liquid chromatography-mass spectrometry apparatus was used for targeted and untargeted analysis of rat neurochemistry.\u0000Results: Increased brain glutamate levels characteristic of MK-801 peptide-treated rats were significantly reduced by AKH. Furthermore, AKH also increased brain dopamine levels in both naive and MK-801 rats. Metabolomic studies have shown that AKH affects lipid and glutamate metabolism, while hypertrehalosaemic hormone plays a role in sugar metabolism and inflammation.\u0000Conclusion: According to our results, AKH might affect dopaminergic and glutamatergic systems and reverse the effects of MK-801, possibly affecting NMDA receptors.","PeriodicalId":404662,"journal":{"name":"Online Türk Sağlık Bilimleri Dergisi","volume":"63 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138976452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radyolojik Görüntülemelerdeki Artışın Analizi: Altta Yatan Faktörler ve Sonuçları 放射成像增长分析：根本因素和后果

Online Türk Sağlık Bilimleri Dergisi Pub Date : 2023-12-13 DOI: 10.26453/otjhs.1369683

Erbil Arik, M. Öztürk, Onur Taydaş

引用次数: 0