尿路感染在新生儿长期黄疸中的发生率和作用

Eray Tunce, Salih Demirhan, Rabia Gönül Sezer Yamanel
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摘要

研究目的本研究旨在探讨尿路感染(UTI)在早产儿和足月新生儿黄疸持续时间中的频率和作用。材料与方法:这项回顾性研究于 2014 年 1 月至 2018 年 4 月期间在伊斯坦布尔 Zeynep Kamil 妇幼医院进行。研究涉及 391 名因长期黄疸而到我院门诊就诊的新生儿。尿毒症的定义是,通过尿道导管获取的样本中,尿培养生长至少每毫升 10,000 个菌落形成单位(CFU/ml)。出生体重、性别、胎龄、实际年龄、化验结果、患者住院过程、超声波检查结果和光疗史均有记录。结果显示在 391 名黄疸持续时间较长的新生儿中,尿毒症发生率为 2.8%。其中男性 9 例(81.8%),女性 2 例(18.2%)。8 名尿毒症患者(72.7%)为足月儿,3 名(29.3%)为早产儿。尿毒症组患者的光疗史、白细胞尿或亚硝酸盐尿、白细胞计数和血小板计数明显高于对照组。结论长时间黄疸可能是新生儿尿毒症的首发症状。对长期黄疸的新生儿进行常规尿液培养可能会有帮助,尤其是那些有光疗史、白细胞和血小板计数较高的新生儿。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Yenidoğanlarda Uzamış Sarılıkta İdrar Yolu Enfeksiyonunun Sıklığı ve Rolü
Objective: The study aims to investigate the frequency and role of urinary tract infection (UTI) in prolonged jaundice in preterm and term neonates. Materials and Methods: This retrospective study occurred at Zeynep Kamil Maternity and Children's Hospital in Istanbul between January 2014 and April 2018. The study involved 391 neonates who presented to our outpatient clinics with prolonged jaundice. UTI was defined as urine culture growth of at least 10.000 colony-forming units per millilitre (CFU/ml) in samples obtained via urethral catheterization. Birth weight, sex, gestational age, chronological age, laboratory results, hospital courses of patients, ultrasound findings and phototherapy history were recorded. Results: UTI frequency was found to be 2.8% in 391 neonates with prolonged jaundice. Nine of them were male (81.8%), and 2 were female (18.2%). Eight patients with UTI (72.7%) were term and 3 (29.3%) were preterm. History of phototherapy, presence of leukocyturia or nitrituria, white blood cell count, and thrombocyte counts were significantly higher in the UTI group. Conclusion: Prolonged jaundice may be the first sign of UTI in neonates. Routine urine culture in neonates with prolonged jaundice may be useful, especially in those with a history of phototherapy and high white blood cell and thrombocyte counts.
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