American Journal of Clinical and Experimental Medicine最新文献

{"title":"A Novel Approach to Treatment of Pinguecula Using Atmospheric Low-temperature Plasma: A Clinical Case Series","authors":"F. Nejat, K. Jadidi, M. Nejat, Nazanin-sadat Nabavi, Seyede-Yasamin Adnani, Shima Eghtedari","doi":"10.11648/J.AJCEM.20210905.13","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210905.13","url":null,"abstract":"Background: In recent years plasma medicine, played an important role in treating several ocular surface disorders. This study will introduce atmospheric low-temperature plasma (ALTP) for removing the pinguecula. Methods: In the clinical case series, five eyes of five patients (2 patients OD, 3 patients OS) with pinguecula were included. The pinguecula removed and completely healed, using the white handpiece of the plasma generator device (Plexr, GMV s.r.l Grottaferrata, Italy). Refraction parameters, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (BDVA), intraocular pressure (IOP), corneal fluorescein staining (CFS), contrast sensitivity (CS) and dry eye tests including, tear meniscus height (TMH) and tear breakup time (TBUT) were measured before, one month and six months after treatment for all patients. Results: The median size of the pinguecula was 3.5 mm (ranged from 2.5 to 4.5 mm). In all patients, the pinguecula was completely sublimated and after six months of follow-up, no evidence of recurrence was observed. In addition, the patient follow-up did not reveal any considerable complications during or 6 months after the surgery. Conclusion: Overall, the current study showed that, plasma assisted noninvasive surgery (PANIS method) is a simple, office-based, minimally invasive, effective approach to treat pinguecula with no considerable complications but it is noteworthy that, study with higher sample size like clinical trial is needed.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126774400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spirituality Wellbeing and Associated Factors Among Cancer Patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia","authors":"Meketa Gezahegn, Debela Gela, Ketema Bizuwork, T. Gebru","doi":"10.11648/J.AJCEM.20210905.12","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210905.12","url":null,"abstract":"Background: even though worldwide studies explored the spiritual and religious practice can help the effect patients fine-tune the effect of cancer, little is known about spirituality wellbeing in Ethiopia, and therefore this study is important to assess the spirituality and associated factor among cancer patients in Addis Ababa, Ethiopia. Objective: To assesses spirituality wellbeing and associated factors among cancer patients in Tikur Anebessa specialized hospital Addis Ababa, Ethiopia, 2021. Methodology: Institution-based cross-sectional study was conducted among cancer patients (N=385). Attending Tikur Anebessa specialized hospital Addis Ababa. Data were entered into Epi-data version 4.6. And exported to SPSS version 25 for further statistical analysis and were analyzed and use Descriptive statistics. The association between the independent variable has been analyzed and the multivariate analysis has been performed. Result: 422 cancer patients were included in the study. Which gave response rate was (91.3%), seventy-six (19.74%) participants had good spirituality wellbeing, (53.8%) participant were female factor sex of respondents (AOR=1.12 (95%CI=108.3.07), religion education (AOR=2.01 (95%CI=1.12, 2.92), education status (AOR=4.03 (95%CI=1.73, 9.35), and comorbidity (AOR=1.32 (95%CI=1.08, 2.65) significantly associated with spirituality well-being. Conclusion: In this study factor that was the sex of respondents, the educational status of respondents, those respondents having comorbidity, and respondents having religious education were significant associated with spiritual wellbeing to maintain spiritual wellbeing focuses on religious education and focus on the prevention of chronic disease to tackle the comorbidity disease.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126360940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Data on Acute Kidney Injury Caused by Acute Organophosphorus Pesticide Poisoning","authors":"H. Feng, Wujian Peng, Chen Jie, D. Han, Zhang He, Jianrong Huang, Xiaona Shi, Hanhan Kong, Guixia Li","doi":"10.11648/J.AJCEM.20210905.11","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210905.11","url":null,"abstract":"Background: Organophosphorus pesticides (OPs) are widely used in China and some developed countries because they are powerful pesticides with minimal damage to crops. However, OPs are highly toxic, especially to the human lungs, heart, brain, kidneys. Research on the pathogenesis and risk factors of acute kidney injury (AKI) caused by OP poisoning is limited, Researches which tend to have small sample sizes and are commonly case reports. Objective: This study aims to investigate the pathogenesis and risk factors of AKI caused by acute organophosphorus poisoning syndrome (AOPP), in order to enable the adoption of early and reasonable treatment methods, to improve the prognosis of patients. Methods: Retrospective analysis was performed on the laboratory findings of 275 patients with acute OP poisoningl from January 2009 to June 2016. (1) The 275 patients with acute OP poisoning were grouped according to the presence or absence of AKI, and testing was performed for statistical differences in the relevant clinical indicators between the two groups. (2) Univariate analysis was performed to compare the differences in these indicators between the two groups, and indicators with statistically significant differences included in logistic regression and other methods to analyze the risk factors affecting AKI. Results: Among the 275 patients with acute OP poisoning, 92 (33.5%) had AKI. The cure rate of the AKI group was 69.6% and case fatality rate was 1.1% (1/92); the cure rate of the non-AKI group was 73.8% (135/183) and the case fatality rate was 0.5% (1/135); the difference in mortality rate between the two groups was not statistically significant (Z=0.94, P=0.34). Comparison of general information and clinical characteristics revealed that only the mean C-reactive protein (CRP) and SCr levels differed significantly between the two groups (Z=6.55, P<0.001; t'=-3.14, P=0.002). Multivariate logistic regression analysis showed that the time of poisoning, time to blood purification therapy and CRP level were factors influencing the onset of AKI. The relationship between CRP level and logitP(AKI=1) was non-linear, and so no interpretation was made on the OR size. Conclusion: 1. The rate of AKI about acute OP poisoning is 54.4%, Both glomeruli and tubules were involved. 2. The prognosis of patients with AKI is relatively poor. 3. The risk factors influencing AKI caused acute OP poisoning may be related to prolonged time of poisoning, prolonged time to blood purification therapy and high CRP level.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131137281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gabapentin — The Popular but Controversial Anticonvulsant Drug May Be Zeroing in on the Pathophysiology of Disease","authors":"M. Binder","doi":"10.11648/J.AJCEM.20210904.15","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210904.15","url":null,"abstract":"Originally marketed under the brand name Neurontin, the anticonvulsant drug gabapentin has become one of the most widely prescribed—and one of the most controversial—drugs in America. On the market for nearly three decades, the drug has been prescribed for everything from chronic cough to chronic pain and hot flashes to bipolar disorder; but is it the real deal, or is it just the brain-child of aggressive marketing, false advertising, and wishful thinking? This critical review will dissect gabapentin down to its molecular roots and trace its wide-ranging effects to better understand the drug and the persons who use it. It will also discuss how gabapentin (and other anticonvulsant drugs) may be doing something more profound than just treating acute symptoms. An emerging hypothesis contends that psychiatric and related function symptoms are driven by pathological hyperactivity in symptom-related circuits in the brain and that the same abnormality may, over time, be driving the development of a plethora of general medical conditions, including diabetes, high blood pressure, cardiovascular disease, autoimmune diseases, dementia, and cancer. Emerging evidence suggests that the underlying physiological abnormality—an inherent hyperexcitability of the neurological system—is very common, and clinical correlation suggests that it is inherited in a classic autosomal dominant distribution. There is also evidence that the abnormality may be reflected in one’s resting vital signs, an observation that could help carriers identify the trait themselves. Gabapentin, together with other pharmacological (and non-pharmacological) interventions that reduce neuronal excitability, may, in addition to their immediate effects, have the potential to prevent the long-term erosive effects of neuronal hyperexcitability by simply turning down the stress response. Recognition of this could usher in history’s greatest campaign in the fight against sickness and disease.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121655668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Attitude Towards COVID-19 and Its Associated Factors Among Health Care Providers in Ethiopia: A Systematic and Meta-Analysis","authors":"Maru Meseret Tadele","doi":"10.11648/J.AJCEM.20210904.14","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210904.14","url":null,"abstract":"Objective: The main aim of this study is to determine the pooled estimate of good knowledge and positive attitude towards COVID-19 among health care providers in Ethiopia. Methods: This review was registered on PROSPERO with registration number CRD42020213000. PubMed, Advanced Google search, and Google Scholar databases were searched up to June 20, 2020, to identify relevant articles. Result: This research searched a total of, 126 articles, from this articles 19 from PubMed, 6 from advanced Google search, 45 from Google scholar databases, and 56 were pre-print unpublished sources. A total of 3752 study participants within 10 articles were used to pool the prevalence of Knowledge and attitude towards COVID-19 among health care providers in Ethiopia and the pooled prevalence of knowledge and attitude towards COVID-19 was 73.01% with 95% CI (65.8% - 80.21%) and 70.72% (59.68%-81.77%) respectively. Place of residence [AOR= 0.24, 95% CI (0.14–0.43)], and social media use [AOR= 2.51, 95% CI (1.53–4.12)] for knowledge while educational status [AOR= 2.41, 95% CI (1.33–4.39)], and status of knowledge were also identified as factors affecting attitude towards COVID 19 among healthcare providers in Ethiopia. Conclusion: The level of knowledge and attitude towards COVID 19 among healthcare providers working in Ethiopia was very low and variables such as residence and social media use were factors affecting knowledge while educational status and knowledge were factors affecting attitude towards COVID 19 among healthcare providers.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Related Quality of Life and Associated Factors Among HIV Patient on Highly Active Antiretroviral Therapy at Assosa Hospital, Northwest Ethiopia, 2019","authors":"Paulos Jaleta Wondasho, Mulugeta Adimasu","doi":"10.11648/J.AJCEM.20210904.13","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210904.13","url":null,"abstract":"Health-related quality of life is a broad concept reflecting a patient’s general subjective perception of the impact an illness and treatment given for them. It measures an integral part of patient follow up by providing valuable feedback about the disease as well as associated interventions. The aim of this study was to assess health related quality of life and associated factors among HIV patient on highly active antiretroviral therapy at Assossa general hospital. Institution based cross-sectional study design was conducted among HIV positive patient from February, 8 to March, 21st 2018 at Assossa general hospital. Data was collected using medical outcome study HIV questionnaire, systematic sampling technique was used, entered in to Epi-info software version 7 analyzed using the statistical product and service solution version 20. Bivariate at p-value < 0.2 and Multivariate Logistic regression p-value at <0.05 was used to identify factors associated with health related quality of life. Three hundred participants with 96.5% response rate were involved in the study. About fifty six point seven percent of the study participants mean (±SD) score of overall health related quality of life was 54.85±11.3. Participant that had viral load copies of forty and below were AOR=3.19 (95%CI 1.73, 5.91) associated with good health related quality of life and participant who have no recent opportunistic infection were AOR=2.87 (95%CI 1.49, 5.51) associated with good health related quality of life. Therefore, the health related quality of life was good. Occupational status, living condition viral load copies/ml and opportunistic infection showed association with good health related quality of life and Further research was suggested.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"47 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120818243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Family Planning Services in Kersa Woreda, Jimma Zone, Southwest Ethiopia: A Facility Based Cross-Sectional Study","authors":"Tarekegn Jabara, E. Ali, Z. Kaba","doi":"10.11648/J.AJCEM.20210904.12","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210904.12","url":null,"abstract":"Improving quality of care has been a necessary goal for family planning programme worldwide. The unmet need for family planning services in Ethiopia is believed to be high (26%) while the already available services do not appear to be optimally used by potential clients. It was assessed the quality of family planning services provision. Facility based quantitative and qualitative cross-sectional study based on James Bruce analytical framework was employed from May 1-30, 2016. Three hundred one (301) family planning service users for exit interview and 40 female clients observed while taking service and 4 service providers from four health centers participated for in-depth interview. Facility audit was made on four health centers. Linear regression was used for data analysis. Based on the overall satisfaction score; 68.8% of clients were satisfied in family planning services. Having more children, currently breast feeding, discussion of family planning with husband or partner, and family size were the significant predictors of client satisfaction to family planning services. It revealed that, for a single individual increase in family size the satisfaction score decreases on average by 0.8 at p=0.007, CI (0.005-0.034). For a unit increase in need to have more child, client satisfaction decreases by 0.947 at p=0.002, CI (0.019, 0.088). Utilization of information, education and communication material during consultations was low (65%). Providers didn’t assessed critical information’s in more than two third of observed sessions of history taking and physical examinations. Hence, service providers should be sensitized and motivated to give complete information on a method to the client. The way family planning providers comply with guideline recommendations and utilize information, education and communication materials consistently during client consultations need to be designed by respective health centers.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130064769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of Perceived Stigma Among Caregivers of Persons with Severe Mental Illness in Jimma City, Ethiopia: A Cross-sectional Study","authors":"M Muhammed, M. Tesfaye, E. Girma, Mengesha Birkie","doi":"10.11648/J.AJCEM.20210904.11","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210904.11","url":null,"abstract":"Background: Stigma associated with mental illness is a psychosocial consequence that causes indescribable suffering for the victim. Therefore this study aimed to assess the magnitude and factors associated with level of perceived stigma among caregivers of persons with severe mental illness in Jimma city, Ethiopia. Methods: A cross-sectional study was conducted with a face-to-face interview from September 20 to October 20/2012 G.C. Family interview schedule was used to assess perceived stigma. A total of 289 participants were recruited using a consecutive sampling technique. Data were analyzed using SPSS version 16 software. Results: The most frequently endorsed item was having felt grief or depression because of having a mentally ill family member or relative (96.5%). The mean stigma score was 17.8±6.9 and the majority of the respondents (54.7%) had a high stigma score. Caregivers/Family members who were spouse to the patient (AOR=4.25, 95%CI: 1.12–16.13) and longer duration of illness (AOR=3.60, 95%CI: 1.42– 9.44) were associated with higher stigma. But a person with mental illness who had verbal/physical violent behavior towards caregivers/family members and other people at the time of the illness (AOR=0.34, 95%CI: 0.17–0.70) and among those family members who attributed the cause of mental illness as the loss of properties and unsuccessful life (AOR=0.27, 95%CI: 0.08-0.89) at p=0.032. Were associated with low stigma respectively. Conclusions: Perceived stigma was found to be a common problem among caregivers of persons with severe mental illness. Becoming spouse of the person, duration of illness, patient with violent behavior and, those caregivers who attributed the cause of mental illness as the loss of properties and unsuccessful life were significantly associated with perceived stigma.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125332171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of COVID-19 in Children and Adults in City of Lahore Pakistan","authors":"R. Khurshid, A. Jaleel, Farrukh Javaid, Waqas Shabbir, A. M. Siddiqui, Kiran Namoos, O. Khalid","doi":"10.11648/J.AJCEM.20210903.14","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210903.14","url":null,"abstract":"Background and objectives: Coronavirus (COVID-19) is pandemic, has affected almost every country around the world. A retrospective multi-centered study was carried out to determine the frequency of COVID-19 in children and adults in Lahore, Pakistan from March 2020 to May 15 2020. The study was included 574 corona positive (PCR–positive) patients of all age groups including 147 children. Record of the patients who visited emergency with symptoms of Corona like fever, sore throat, and respiratory distress and those admitted in hospitals due to corona illness was analyzed. Travelling history was recorded and frequency determined using SPSS ver 21. Data of study showed that 54% middle aged patients were found to suffer with Corona virus followed by children and 23% old age group. The patients belong to middle / low socioeconomic status. 26 patients had international travel history while 49 travelled domestically. Study concluded that the incidence of coronavirus disease was more in middle age men followed by children and old age group. However, it is found that the incidence of virus observed in children with better recovery than other age groups. In most of the cases, the course of disease is mild to moderate with less mortality rate.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133395288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Needle Stick or Sharp Injuries & Associated Factors Among Medical Students at Debre Tabor University","authors":"Eleni Girma Woldearegay, Biniam Ewnte Zelelew","doi":"10.11648/J.AJCEM.20210903.13","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20210903.13","url":null,"abstract":"Background: Medical students throughout the world show a high rate of sharp injuries with a consequent risk of acquiring blood-borne infections while performing their clinical activities. Objective: This study was conducted to assess needle stick or sharp injuries among medical students of Debre Tabor University, and to identify the associated factors leading to Needlestick or sharp injury. Method: An institution-based cross-sectional study was conducted among 4th to 6th-year medical students at Debre Tabor University, by using census sampling through a self-administered semi-structured questionnaire, and the completeness of the questionnaires was assessed daily. Data were processed and analyzed using SPSS software version 21.0 and bivariate analysis was obtained using a logistic regression model. In addition, tables and figures were used as necessary to represent the data. Result and conclusion: According to our study, the prevalence of Needle stick or sharp injuries among medical students in clinical years other than clerkship I students in Debre Tabor University was found to be 28.5%. Medical interns were particularly affected with a prevalence rate of 66.6%. The associated factors with Needlestick or sharp injuries included the academic year of study and the department where the injury occurred.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125318371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}