American Journal of Clinical and Experimental Medicine最新文献

{"title":"Clinical Pathological Features of Peripheral T Cell Lymphoma with Concurrent Bone Marrow Involvement","authors":"Mohamed Masoud, C. Xie, Jessica Q Zhou, Xia Chen, M. Xie","doi":"10.11648/j.ajcem.20180601.14","DOIUrl":"https://doi.org/10.11648/j.ajcem.20180601.14","url":null,"abstract":"Peripheral T cell lymphomas (PTCLs) are uncommon and less well studied. Most PTCLs present as systemic disease and often involve bone marrow. Bone marrow involvement by PTCLs may damage the normal hematopoiesis and bring more challenge to clinical management of these patients. This study focuses on the clinical pathological features and clinical outcomes in 13 patients with nodal peripheral T cell lymphoma and subsequent bone marrow biopsy positive for the same lymphoma. Eight patients were diagnosed of peripheral T cell lymphoma - not otherwise specified (PTCL-NOS), 3 angioimmunoblastic T cell lymphoma (AITL), 1 anaplastic large cell lymphoma (ALCL), and 1 T cell lymphoma of gamma-delta origin (TCL-gamma/delta). All patients had peripheral blood abnormalities: 11 anemia, 7 thrombocytopenia, 5 neutropenia, and 2 lymphocytosis. Of interest, the CD4/CD8 phenotype of PTCL was shown correlating with abnormal peripheral blood findings: CD4+/CD8- phenotype was more often associated with anemia and thrombocytopenia, and CD4-/CD8+ phenotype was associated with lymphocytosis. Chemotherapy remains the choice of first line treatment for these patients with or without stem cell transplantation. 12 patients had treatment and follow up data available for review, 5 were in remission or free of disease during the follow up period; 5 patients were alive or in hospice with persistent disease and 2 died of disease due to multiple complications. The outcome of PTCL treated with the standard chemotherapy has been less favorable compared with B cell lymphomas. Majority of the patients with nodal PTCL have bone marrow involvement at the time of initial diagnosis, which has significant impact on normal hematopoiesis and may be a significant factor in the overall unfavorable prognosis for these patients. Further investigation with better knowledge about this disease will be helpful in the development of more efficient therapy and improve the disease free survival and life quality for these patients.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"46 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121001944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Health Care Condition in Yemen (Aden)","authors":"A. Hasan, M. Sayyad","doi":"10.11648/J.AJCEM.20180601.13","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20180601.13","url":null,"abstract":"Patient safety is a serious global public health issue. In recent years the importance of improving patient safety has been a major concern all over the world. The government of Yemen, like governments of other developing countries has been providing a wide range of free healthcare services to its people over a long period of time. The increase in health related problems in Yemen is due to lifestyle changes and lack of adequate care by the hospitals. Accordingly, the Ministry of Public Health and Population (MoPHP) in Yemen realized that the public sector alone is no longer capable of providing necessary health care for the people of Yemen and therefore privatized the sector to a large extent. This paper is aimed at focusing on the current health care situations available in Yemen. The secondary data of the health care related aspects are presented and discussed retrospectively. We present a review of current health care status in Yemen through a retrospective data with reference to Aden city and also discuss the possible measures need to be implemented in order to improve the situation. The paper discusses the evaluation of the health care standards in Yemen and also explores the reasons for medical tourism of Yemeni nationals to other countries like India.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126883827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Capabilities of Ultrasound Diagnosis in Assessment of Gastric Carcinoma of Different Localization and Stage","authors":"R. Abdullaiev, I. Kryzhanovskaya, Y. Vinnik, P. Gorleku","doi":"10.11648/j.ajcem.20180601.12","DOIUrl":"https://doi.org/10.11648/j.ajcem.20180601.12","url":null,"abstract":"Objective: To evaluate the diagnostic possibilities of transabdominal ultrasonography for various localizations of gastric carcinoma (GC). Materials and Methods: The study included 101 patient with GC, the stage T1 in 5, the stage of T2 – in 12, the stage of T3 – in 39 and the stage of T4 – in 45 cases respectively. The stomach tumor in 37 (36.6%) cases was localized mainly in the antrum, 35 (34.6%) – in the body, 12 (11.9%) in the cardia and fundus, in 13 (12.9%) cases it had a total, in 4 (4.0%) - subtotal character. Ulcerating infiltrating forms (UIF) of GC was diagnosed in 71 cases, diffuse infiltrating forms (DIF) in 23 cases. All patients underwent preoperative X-ray, virtual gastroscopy techniques, multidetector computed tomography and transabdominal ultrasonography (USG). Results: The intestinal histological form of GC was detected in 7 cases – with USG in 6 cases. The UIF of GC with the help of USG was diagnosed in 69 (97,2%) cases, DIF – in 23 (100%) cases of T2-T4 stages. The results of USG and CT was coincided in all cases of T3 and in 92,7% of T4 stages of GC. Conclusions: The combined use of ultrasonography and gastroscopy will increase the detection of early intestinal type of GC. USG is the best, cheap, independent method for diagnosing a diffusely infiltrative form of GC, especially of the antrum. At stage T3, he is not inferior to CT in assessing the localization and prevalence of GC, and at stage T4, the difference between them is negligible.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127915732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Biofield Energy Healing Treated Vitamin D3 on Human Osteoblast Cell Line (MG-63) for Bone Health","authors":"William Dean Plikerd, M. Trivedi, A. Branton, Dahryn Trivedi, G. Nayak, M. Gangwar, S. Jana","doi":"10.11648/J.AJCEM.20180601.11","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20180601.11","url":null,"abstract":"Bone disorders are largely associated with increased morbidity, mortality, and substantial economic and health costs. Vitamin D play an important role for calcium absorption and bone mineralization, which can improve the patients' quality of life. The current study aimed to evaluate the potential of The Trivedi Effect ® - Biofield Energy Healing on vitamin D 3 and DMEM as test item (TI) on bone cell differentiation using human osteoblast cell line (MG-63, Osteosarcoma). Bone health biomarkers such as alkaline phosphatase enzyme (ALP) activity, collagen levels and bone mineralization were evaluated. The test items were treated with The Trivedi Effect ® by William Dean Plikerd and divided as Biofield Energy Treated (BT) and untreated (UT) test items. Cell viability using MTT data showed that the test items were found to be safe. ALP level was significantly increased by 346.4% (at 50 µg/mL), 375.3% (at 100 µg/mL), and 343.2% (at 100 µg/mL) in the UT-DMEM+BT-TI, BT-DMEM+UT-TI, and BT-DMEM+BT-TI groups, respectively as compared to the untreated group. Collagen content was significantly increased by 336.2% and 237.2% in the UT-DMEM+BT-TI at 10 and 50 µg/mL, respectively while 399.3% and 110.2% increased collagen at 10 µg/mL in BT-DMEM+UT-TI and BT-DMEM+BT-TI groups, respectively. Moreover, the percent of bone mineralization was significantly increased in BT-DMEM+BT-TI group by 71.3% and 97.2% at 50 and 100 µg/mL, respectively as compared with the untreated test item and DMEM group. Thus, Biofield Energy Treated vitamin D 3 and DMEM would play an important role to control the osteoblast function, improves bone mineralization, and calcium absorption in many bone disorders. Moreover, the bone health parameters such as collagen, calcium and ALP were significantly improved and can be used as supplement to improve bone health. Based on the outstanding results, it is assumed that the Biofield Energy Treated vitamin D3 could be a powerful alternative dietary sources and supplements to fight against various bone related diseases including low bone density and osteoporosis, osteogenesis imperfecta, Paget’s disease of bone, rickets, osteomalacia, bone and/or joint pain, increased frequency of fractures, deformed bones, osteoma, chondrodystrophia fetalis, hormonal imbalance, stress, aging, bone loss and fractures.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114661586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semaphorin 3B Gene Suppresses Tumor Growth Through the p53 Signaling Pathway and Neuropilin Receptors","authors":"Yan Ma, Mingming Fang, Xifa Zhou","doi":"10.11648/j.ajcem.20170506.18","DOIUrl":"https://doi.org/10.11648/j.ajcem.20170506.18","url":null,"abstract":"The semaphorin family has been demonstrated to possess tumor suppressor activity; semaphorin 3B (SEMA3B) is differentially expressed in several types of tumors, and has been identified as a tumor suppressor gene. SEMA3B is shown to be a target gene of p53, and it suppresses tumor growth through the p53 signaling pathway. The mechanisms underlying tumor suppression by SEMA3B include neuropilin receptors (NRP1 and NRP2), which reduce the action of vascular endothelial growth factor (VEGF), thus, inhibiting tumor angiogenesis. Deficiency or down-regulation of SEMA3B expression can be found in a variety of malignant tumors including lung cancer, ovarian cancer, nervous system tumors, and hepatobiliary tumors, and this suppression involves methylation, loss of heterozygosity (LOH) and enzyme cleavage. This review summarizes recent research approaches on the tumor suppression effects and mechanisms of SEMA3B.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130452074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation-Induced Changes in Structural Network in Patients with Nasopharyngeal Carcinoma","authors":"Yin Tian, Yi Zhao","doi":"10.11648/j.ajcem.20170506.17","DOIUrl":"https://doi.org/10.11648/j.ajcem.20170506.17","url":null,"abstract":"Radiation therapy (RT) is the standard radical treatment for nasopharyngeal carcinoma (NPC), and has produced excellent effects in terms of survival rate [1, 2]. However, one of the serious complications gave rise by the RT is brain injury. Previous studies have found that RT could cause brain structural abnormalities on gray matter and white matter. Nevertheless, the RT effects on the network level should be further investigated. Herein, we explored changes on the structural network for patients with NPC induced by RT. The structural magnetic resonance data (sMRI) were used to investigate the structural network in 20 NPC patients after and before radiotherapy. After constructing the structural network, we examined the radiation-induced changes in topology properties of small world network using graph theoretical analysis. Our results found that both the before and after radiotherapy groups showed small world properties. Compared with the before radiotherapy (pre-RT) group, the after radiotherapy (post-RT) group had lower global and local efficiency, longer shortest path length, and less clustering coefficient. In addition, the hub regions in the post-RT group were significantly different from the pre-RT group. Our findings exhibited the architecture of network topology and information transfer efficiency became poor in post-RT group. We speculated radiation therapy might induce the differences. The results can provide a new perspective to explore and diagnose radiation-induced brain injury and evaluate the effect of radiotherapy.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132104960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraceptive Use Among Women Living with HIV and AIDS Receiving Care at Secondary and Tertiary Health Care Facilities in Ibadan, Nigeria","authors":"Adenuga Faidat Adesola, B. Solomon, Titiloye, Musibau Ayoade, Oladepo Oladimeji, Ngene Samuel Osobuchi","doi":"10.11648/j.ajcem.20170506.16","DOIUrl":"https://doi.org/10.11648/j.ajcem.20170506.16","url":null,"abstract":"Contraceptive use is a form of family planning and it is one practice among the most important health decisions that many people make and this does not exclude women living with HIV/AIDS. Lack of adequate information on available contraceptive methods and restriction of choices are the major constraints for contraceptive users to obtain a method that suits their need. Consequently, this study was designed to assess contraceptive use among women living with HIV and AIDS receiving care at secondary and tertiary health care facilities in Ibadan, Nigeria. A cross-sectional study using systematic sampling technique was conducted to select 350 consenting women among HIV positive women receiving care in two health facilities in Ibadan, Nigeria. A pre-tested interviewer administered questionnaire was used to obtain information on respondent’s socio-demographic characteristics, contraceptive usage and level of satisfaction of modern contraceptive method. Data were analyzed using SPSS version 22. Chi-square statistic was used to test associations between categorical variables at a level of statistical significance of 5%. The mean age of respondents was 37.0±8.5 years and about 87.0% were currently married. The current prevalence of contraceptive was 67.7%. Condom was the most currently preferred contraceptive method (54.0%), followed by injectable (12.2%) and oral pills (11.0%). About 83.1% was satisfied with their current method of contraception. The most cited reason by those who were not satisfied with their current contraceptive method irregular menses (30.0%). The factors that were significantly associated with contraceptive use were maternal age, marital status, type of marriage, level of education and parity decision (P < 0.05). High level of contraceptive uptake and satisfaction was observed in this study. However, irregular menses was a common complaint of those who were not satisfied with their current method. Family planning programme should be incorporated as a component part of care for women living with HIV and AIDS.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129521212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Immune Biomarkers After Oral Administration of the Novel Herbomineral Formulation Treated with The Trivedi Effect® - Biofield Energy Healing in Male Sprague Dawley Rats","authors":"M. Trivedi, A. Branton, Dahryn Trivedi, G. Nayak, M. Ellis, J. Peoples, James Joseph Meuer, J. Dodon, J. Griffin, J. Suzuki, Joseph Michael Foty, J. Weber, Julia Grace McCammon, K. B. Allen, Kathryn Regina Sweas, Lezley Jo-Anne Wright, Lisa A. Knoll, Madeline E. Michaels, M. Wahl, Mark E. Stutheit, M. Barnard, Muriel Mae Ranger, Paromvong Sinbandhit, V. J. K. Elig, Sambhu Mondal, S. Jana","doi":"10.11648/j.ajcem.20170506.15","DOIUrl":"https://doi.org/10.11648/j.ajcem.20170506.15","url":null,"abstract":"Herbomineral formulations have been used worldwide against various chronic and degenerative diseases due to its fewer side effects. A new proprietary herbomineral formulation was formulated consisted of an ashwagandha root extract and minerals (zinc, magnesium, and selenium). The present study was aimed to evaluate the impact of the Biofield Energy Treated herbomineral formulation in male Sprague Dawley (SD) rats for immune biomarkers modulation. The test formulation was divided into two parts. One part was denoted as the control without any Biofield Energy Treatment, while the other part was defined as the Biofield Energy Treated sample, which received the Biofield Energy Healing Treatment remotely from twenty renowned Biofield Energy Healers. Biomarkers like immunoglobulins (IgG, IgM), cluster differentiation (CD4+), CD8+, superoxide dismutase (SOD), catalase (CAT), lipid peroxidation (LPO) were monitored. The level of IgM was increased by 4.76% in the Biofield Energy Treated test formulation (G4) compared to the disease control group (G2). The levels of CD4+ and CD8+counts were significantly (p≤0.01) increased by 222.22% and 355.36% in the G4 group compared to the G2 group. The level of lymphocyte was increased by 5% and eosinophil count was significantly decreased by 75% in the G4 group compared to the G2 group. The lipid biomarkers such as total cholesterol (TC), low density lipoprotein (LDL), and very low density lipoprotein (VLDL) were significantly lowered by 9.70%, 6.67%, and 23.54%, respectively in the G4 group compared to the G2 group. The expression of SOD was reduced by 9.96% in the G4 group compared to the G2 group. Further, LPO expression was significantly reduced by 33.38% and 16.88% in the G4 and untreated test formulation (G5) groups, respectively compared to the G2 group. Therefore, it can be concluded that the Biofield Energy Treated test formulation showed significantly improved the cellular and humoral immunity, hematological and biochemical profile compared with the untreated test formulation. As a result, it can be established that The Trivedi Effect®-Biofield Energy Healing has the significant capacity for immunomodulatory effect, which may also be useful in organ transplants, anti-aging, and stress management by improving overall health and quality of life.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"166 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116113361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Manifestation of Kaposi's Sarcoma in Patient with AIDS: Case Report","authors":"E. Giovani, B. Caputo, R. Andia-Merlin, Camila Correia dos Santos, Rodolfo Georgevich Neto, K. Marinho, Claudio Costa, Fátima Cristina Carneiro Marques, Alfredo Mikail Melo Mesquista, Gilberto Araújo Noro Filho","doi":"10.11648/J.AJCEM.20170506.14","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20170506.14","url":null,"abstract":"In the early 1980s, acquired immunodeficiency syndrome was recognized and described in men who had sex with previously healthy men and young people, who were affected by atypical pneumopathy caused by an opportunistic microorganism, identified as Pneumocystis carinii , and now known as Pneumocystis jiroveci , evidenced by purplish or brown nodular lesions revealed in the histopathological Kaposi's sarcoma. Kaposi's sarcoma is the most frequent neoplasm in patients with human immunodeficiency virus infection. Its pathophysiology has been associated with the presence of a herpes virus, whose etiologic agent is a member of the herpesvirus or herpes virus type 8 family(HHV-8), which can be transmitted through sexual contact, which would be implicated in the onset of the disease. This case report seeks to present the diagnosis and bring the light of knowledge to the Dentist the need to launch hands of complementary examinations and to effectively seek important therapeutic measures in the treatment of the pathology. In this case, with the start of HAART administration, the tumor regressed, leading the patient to well being, and with evident improvements in their quality of life.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131756551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nocturnal Enuresis as a Specific Compensatory Syndrome","authors":"A. Golbin, A. Tsarenko","doi":"10.11648/J.AJCEM.20170506.13","DOIUrl":"https://doi.org/10.11648/J.AJCEM.20170506.13","url":null,"abstract":"The pathophysiological nature of the monosymptomatic primary nocturnal enuresis (PNE) in children is still the unresolved problem. The most hypotheses of pathogenesis of nocturnal enuresis are limited within anatomical, biochemical and physiological regulation of the urinary control. Based on our own observations as well as the data reported in the literature, we have concluded that in addition to described biological causes of this disorder, we should focus on the common clinical and developmental features observed in the majority of cases of the monosymptomatic primary nocturnal enuresis that could be united as “enuretic syndrome”. In attempt to move “outside of the box” of the urinary control we have put forward a hypothesis that enuresis is a specific compensatory syndrome which is self-developed by the child’s organism to “offset” the deviated sleep–wake mechanisms. This concept is based on the general “control system theory” and offers the explanations of the majority of symptoms. From the compensatory “offset” concept the treatment of PNE should be focused not on the suppression of the act of enuresis but on the stabilization of circadian sleep-wake mechanisms. Further investigations are needed to evaluate the validity of this concept.","PeriodicalId":404444,"journal":{"name":"American Journal of Clinical and Experimental Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132425210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}