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Journal of Advanced Lung Health最新文献

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Air regurgitation through the nasolacrimal duct in a patient on bi-level positive airway pressure therapy 双水平气道正压治疗患者鼻泪管空气反流
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_40_22
A. Paul, S. Mathew, B. Thomas
{"title":"Air regurgitation through the nasolacrimal duct in a patient on bi-level positive airway pressure therapy","authors":"A. Paul, S. Mathew, B. Thomas","doi":"10.4103/jalh.jalh_40_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_40_22","url":null,"abstract":"Positive airway pressure therapy is usually a well tolerated mode of treatment used for managing patients with various diseases where either oxygenation or ventilation is compromised. Air regurgitation through the naso lacrimal duct (NLD) is a rare complication of positive airway pressure therapy. There are multiple valves in the nasolacrimal duct to prevent the retrograde airflow from the nasal cavity to the lacrimal sac, under normal physiological conditions. Failure of this multi level valve system will lead to the retrograde air flow from the nasal cavity to reach the lacrimal puncta via the nasolacrimal duct. Valve insufficiency by birth or due to a prior procedure done at this region could be the underlying cause for this complication. In this case report, we discuss about the appearance of air regurgitation in a patient with chronic obstructive pulmonary disease on bi-level positive airway pressure (BiPAP) therapy and we also discuss on the causes for this complication and the various treatment modalities to manage this condition.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122438464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profile of pulmonary hypertension in patients presenting with respiratory symptoms at a tertiary care hospital in Mumbai 孟买一家三级保健医院出现呼吸道症状的患者肺动脉高压概况
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_27_22
U. Desai, K. Utpat, MK Kanmani, Vinod Pal, J. Joshi
{"title":"Profile of pulmonary hypertension in patients presenting with respiratory symptoms at a tertiary care hospital in Mumbai","authors":"U. Desai, K. Utpat, MK Kanmani, Vinod Pal, J. Joshi","doi":"10.4103/jalh.jalh_27_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_27_22","url":null,"abstract":"Background: Pulmonary hypertension (PH) is a disorder of the pulmonary vasculature caused due to vasoconstriction, vaso-destruction, or vaso-obliteration as a complication of a varied spectrum of diseases referred to a pulmonologist. We conducted this study to contemplate the profile of PH in a tertiary care hospital in Mumbai. Methodology: This was an observational study undertaken in the department of pulmonary medicine at a tertiary care center after internal ethical committee approval. Patients with respiratory symptoms referred to us with PH as estimated pulmonary artery systolic pressure (PASP) of ≥40 mmHg by transthoracic two-dimensional echocardiography (corresponding to mean pulmonary artery pressure of ≥25 mmHg) were included in the study. The profile of these patients was studied on basis of parameters such as demography, etiology, symptomatology, radiological features, 6-min walk distance (6-MWD), and spirometry. Data were analyzed using Microsoft Excel software. Results: Among 347 patients, 54% were men. Majority of the patients (53.5%) were aged between 45 and 65 years. The most common symptom was dyspnea (86%). The most common examination finding was loud pulmonary component of second heart sound (62%). The common etiologies of PH were postinfectious obliterative bronchiolitis (OB) 30%, interstitial lung diseases 26%, chronic obstructive pulmonary disease 24%, and obstructive sleep apnea 14%. There was a negative correlation between 6-MWD, forced vital capacity % predicted, forced expiratory volume in 1st s % predicted, and PASP. Conclusion: Airway disease is the most common etiology of PH in patients presenting to a pulmonologist in India, out of which postinfectious OB forms the major bulk.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128785927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The sunshine vitamin 阳光维生素
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_6_23
K. Narayan
{"title":"The sunshine vitamin","authors":"K. Narayan","doi":"10.4103/jalh.jalh_6_23","DOIUrl":"https://doi.org/10.4103/jalh.jalh_6_23","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131081996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydropneumothorax – Rare presentation of pulmonary embolism with methylenetetrahydrofolate reductase mutation with hyperhomocysteinemia 气胸-罕见的肺栓塞与亚甲基四氢叶酸还原酶突变与高同型半胱氨酸血症
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_35_22
Saby Kunjumon, N. Neenu, K. Utpat, U. Desai, K. Raj, Sharad N. Sable
{"title":"Hydropneumothorax – Rare presentation of pulmonary embolism with methylenetetrahydrofolate reductase mutation with hyperhomocysteinemia","authors":"Saby Kunjumon, N. Neenu, K. Utpat, U. Desai, K. Raj, Sharad N. Sable","doi":"10.4103/jalh.jalh_35_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_35_22","url":null,"abstract":"Pulmonary embolism (PE) is a relatively common cardiovascular event with high early mortality rates. Many risk factors play a role in the causation of PE including acquired as well as inherited. Methylenetetrahydrofolate reductase (MTHFR) gene mutation is one of the inherited etiologies for PE which cause hyperhomocysteinemia which can lead to PE. This in turn can result in secondary complications such as pneumothorax or hydropneumothorax, which are rare presentations of PE. Hereby, we present this unique case of a 17-year-old boy who presented with a hydropneumothorax which on further evaluation was found to be a complication of bilateral PE which was due to hyperhomocysteinemia with MTHFR A1298C mutation. Hence, we present this unique case with rare presentation as well as rare etiology for PE. This shows the significance for considering PE as one of the differentials in situations such as cavitations, pneumo or hydropneumothoraces, and hyperhomocysteinemias.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"30 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120918593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare disease with interesting radiologic findings 罕见病，影像学表现有趣
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_17_22
Gayathri Karedath, B. Pallivalappil
{"title":"A rare disease with interesting radiologic findings","authors":"Gayathri Karedath, B. Pallivalappil","doi":"10.4103/jalh.jalh_17_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_17_22","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116856691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Once a remedy, later a disease 一日良药，日后成病
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_33_22
K. Shikha, Sudin Koshy, P. Arjun
{"title":"Once a remedy, later a disease","authors":"K. Shikha, Sudin Koshy, P. Arjun","doi":"10.4103/jalh.jalh_33_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_33_22","url":null,"abstract":"Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation therapy (RT). It manifests acutely as radiation pneumonitis (RP) and chronically as radiation pulmonary fibrosis. It is usually seen in patients who have undergone thoracic irradiation for the treatment of lung, breast, or hematologic malignancies. The volume of lung irradiated and the mean lung dose are important risk factors. The diagnosis is usually based on a combination of typical symptoms (e.g., cough, dyspnea, and occasionally fever), timing, dose, and location of radiation therapy, compatible imaging findings, and exclusion of other causes. We report a case of a patient with breast cancer, who had received locoregional radiotherapy (RT) and then palliative RT for metastasis in the rib, following which she developed symptoms and radiological manifestations consistent with RILI. The patient recovered clinically and radiologically with conservative management. It was important to accurately diagnose the entity early since RP with moderate-to-severe symptoms and impaired respiratory function needs to be treated early to prevent irreversible lung damage.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121506975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanotransduction in fibrosis 纤维化中的机械转导
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_1_23
R. Chetambath, N. Ravindran
{"title":"Mechanotransduction in fibrosis","authors":"R. Chetambath, N. Ravindran","doi":"10.4103/jalh.jalh_1_23","DOIUrl":"https://doi.org/10.4103/jalh.jalh_1_23","url":null,"abstract":"Mechanotransduction is the phenomenon of conversion of mechanical forces to biochemical signals in fibrosis. Knowledge on how mechanotransduction influences the behavior of cells and tissues will help to identify novel therapeutic targets for mechanomodulatory approaches. Innovative therapies based on these advances will potentially transform fibrotic healing into tissue regeneration.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116731591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air–Fluid level in the chest X-Ray after pneumonectomy 全肺切除术后胸片的气液水平
Journal of Advanced Lung Health Pub Date : 2023-05-01 DOI: 10.4103/jalh.jalh_34_22
V. Moleyar, Joan Jacob
{"title":"Air–Fluid level in the chest X-Ray after pneumonectomy","authors":"V. Moleyar, Joan Jacob","doi":"10.4103/jalh.jalh_34_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_34_22","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131261547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung involvement in chronic occult aspiration 慢性隐匿性误吸累及肺部
Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_31_22
Gayathri Karedath, K. Kumar, V. Chinmay Nandini, M. Krishnaprasad, E. Shabana
{"title":"Lung involvement in chronic occult aspiration","authors":"Gayathri Karedath, K. Kumar, V. Chinmay Nandini, M. Krishnaprasad, E. Shabana","doi":"10.4103/jalh.jalh_31_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_31_22","url":null,"abstract":"Chronic occult aspiration is the chronic aspiration of small volumes of oral and gastric contents into the lung. This is also termed as chronic microaspiration. It can lead to symptoms of gastroesophageal reflux disease and later lung involvement. This process is less familiar than the acute aspiration syndromes. Here, we present the case of an elderly male patient having diffuse esophageal spasm manifesting as recurrent chest pain and interstitial lung disease.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122683122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signs may sometimes mislead you 星座有时会误导你
Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_29_22
K. Kumar, V. Chinmay Nandini, R. Chetambath
{"title":"Signs may sometimes mislead you","authors":"K. Kumar, V. Chinmay Nandini, R. Chetambath","doi":"10.4103/jalh.jalh_29_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_29_22","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124081233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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