Journal of Advanced Lung Health最新文献_第5页

Prechronic obstructive pulmonary disease 慢性阻塞性肺疾病

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_36_22

R. Chetambath

引用次数: 0

Signet-ring cell adenocarcinoma of the lungs: An unusual and rare case 肺印戒细胞腺癌:罕见病例

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_30_22

R. Chetambath, Nadini Sylesh, KPraveen Kumar, Gayathri Karedath, A. Chacko

引用次数: 0

Transbronchial lung biopsy in interstitial lung diseases at a tertiary care center in Western India 经支气管肺活检在间质性肺疾病在印度西部三级保健中心

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_14_22

K. Utpat, Rakesh Rajpurohit, M. Dharani, U. Desai, A. Moses Ezhil Raj, Saby Kunjumon, S. Sharad, S. Bhalerao

{"title":"Transbronchial lung biopsy in interstitial lung diseases at a tertiary care center in Western India","authors":"K. Utpat, Rakesh Rajpurohit, M. Dharani, U. Desai, A. Moses Ezhil Raj, Saby Kunjumon, S. Sharad, S. Bhalerao","doi":"10.4103/jalh.jalh_14_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_14_22","url":null,"abstract":"Background: Interstitial lung diseases (ILDs) are a heterogeneous group of disorders with a wide spectrum. Diagnosis of ILD is by a multidisciplinary approach with clinical, radiological, and histopathological correlation. With the increasing knowledge on the clinical and radiological spectrum, there is a renewed interest to clarify and research the pathological aspect too. Materials and Methods: A retrospective study was conducted at a tertiary care hospital based on the available medical records of 65 patients with IEC permission. The role of transbronchial lung biopsy (TBLB) in diagnosing ILD was studied by comparing with high-resolution computed tomography findings. Data were analyzed in percentages. Results and Interpretation: Out of 65 cases, there were 30 cases (46%) of chronic hypersensitivity pneumonitis (HP), 12 cases (18%) of sarcoidosis, 12 cases (18%) of usual interstitial pneumonia (UIP), 9 cases (14%) of nonspecific interstitial pneumonia (NSIP), 1 case (2%) of lymphocytic interstitial pneumonia (LIP), and 1 (2%) case of cryptogenic organizing pneumonia (COP). TBLB yielded pathological diagnosis suggesting ILDs in 65% of patients. In addition, ill-formed granulomas were observed in 14 of 30 (47%) of chronic HP, noncaseating granulomas in 7 of 12 (58%) of sarcoidosis, and diffuse lymphocytic infiltrates and organizing pneumonia pattern in 100% of LIP and COP patients, respectively, whereas yield in cases of UIP and NSIP is 17% and 33%, respectively. Conclusion: Thus, TBLB is a promising minimally invasive technique for diagnosing ILD with a total yield of 65%. More specifically, the yield is more in cases of sarcoidosis, chronic HP, and rare ILDs such as LIP and COP, as compared to UIP and NSIP.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"666 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121993421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interstitial lung diseases and lung biopsies… more, less, or nothing… 肺间质性疾病和肺活检…多，少，还是没有…

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_39_22

AR Paramez

引用次数: 0

Ultrasonography in Emergency – Seeing Beyond the Apparent 急诊超声检查-超越表象

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_8_22

Nitesh Gupta, A.J. Mahendran, Ankit Sharma, P. Ish, Rohit Kumar, M. Madan

引用次数: 0

Newer therapeutic options in chronic obstructive pulmonary disease 慢性阻塞性肺疾病的新治疗选择

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_23_22

Jesin Chakkamadathil

引用次数: 0

The Role of initial and follow-up C-reactive protein titer in COVID-19 pneumonia: A single-center study of 1000 cases in a tertiary care setting in India 初始和随访c反应蛋白滴度在COVID-19肺炎中的作用:印度三级医疗机构1000例病例的单中心研究

Journal of Advanced Lung Health Pub Date : 2023-01-01 DOI: 10.4103/jalh.jalh_20_22

S. Patil, G. Narwade, U. Dhumal

{"title":"The Role of initial and follow-up C-reactive protein titer in COVID-19 pneumonia: A single-center study of 1000 cases in a tertiary care setting in India","authors":"S. Patil, G. Narwade, U. Dhumal","doi":"10.4103/jalh.jalh_20_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_20_22","url":null,"abstract":"Introduction: Robust data of C-reactive protein (CRP) are available in bacterial infection, and it can be utilized in this coronavirus disease 2019 (COVID-2019) pneumonia pandemic for initial assessment before planning of treatment in indoor setting compared to other inflammatory markers and computerized tomography (CT) severity. Methods: A prospective, observational, 12-week-follow-up study, included 1000 COVID-19 cases confirmed with real-time reverse transcription-polymerase chain reaction; all cases were assessed with lung involvement documented and categorized on high-resolution computerized tomography (HRCT) thorax, oxygen saturation, and inflammatory marker as CRP at entry point and follow-up. Age, gender, comorbidity, use of bilevel positive airway pressure/noninvasive ventilation (BiPAP/NIV), and outcome as with or without lung fibrosis as per CT severity were key observations. Statistical analysis is performed using Chi-square test. Results: The HRCT severity score at entry point has significant correlation with CRP titer [P < 0.00001]. CRP titer has significant association with duration of illness (P < 0.00001). Comorbidities has significant association with CRP titer (P < 0.00001). CRP titer has significant association with oxygen saturation at entry point (P < 0.00001). BiPAP/NIV requirement during hospitalization has significant association with CRP titer (P < 0.00001). Timing of BiPAP/NIV requirement has significant association with CRP titer (P < 0.00001). Follow-up CRP titer during hospitalization compared to entry point normal and abnormal CRP has significant association in post-COVID lung fibrosis (P < 0.00001). Conclusions: CRP has documented a very crucial role in COVID-19 pneumonia in predicting severity of illness, progression of illness, and sequential CRP titers that will help assessing response to treatment during hospitalization and analyzing post-COVID lung fibrosis.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122644814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The pain of pills: The lived experiences of cured tuberculosis patients 药片的痛苦:结核病治愈患者的生活经历

Journal of Advanced Lung Health Pub Date : 2022-09-01 DOI: 10.4103/jalh.jalh_7_22

Janmejaya Samal

{"title":"The pain of pills: The lived experiences of cured tuberculosis patients","authors":"Janmejaya Samal","doi":"10.4103/jalh.jalh_7_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_7_22","url":null,"abstract":"Background: Tuberculosis (TB) continues to be a major public health threat in India. Management of TB requires intake of multiple pills during the entire treatment period with strong repugnance by the patients and the family members as well. Objective: The main objective was to understand the difficulties and challenges faced by TB patients while undergoing TB treatment. Materials and Methods: Cured TB patients from urban slums in one of the cities of Chhattisgarh were interviewed in depth by the help of an open-ended semi-structured questionnaire. The interviews were transcribed verbatim and subsequently underwent an inductive thematic analysis. Results: Of the 12 study participants, 25% constituted female patients; 16.6% constituted relapse cases; 16.6%, 8.3%, and 75% of the cases were diagnosed through chest X-ray, cartridge-based nucleic acid amplification test, and sputum examination, respectively. All the cases belong to an urban slum and are pulmonary TB cases. Two major thematic areas and 2 sub-themes were identified; (a) Pain of Pills (1. Load of pills, 2. Adverse effects of anti-TB drugs) and (b) Social Stigma (1. Concealment of treatment status, 2. Concealment of treatment success). Owing to the long duration of treatment, TB patients develop strong aversion toward pills and wish to complete the treatment before prescribed time-limit. Despite the progress made, TB patients are still being stigmatized in communities and many TB sufferers neither want to share their status as TB patients nor want to share the treatment success in their neighborhood. Sometimes, these patients feel exhausted, isolated and live with solitude with self-discrimination. Conclusion: Health-care workers should be compassionate toward the stigma and aversion for treatment that becomes a part of many TB patient's life.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"364 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123128254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 vaccine-related immunological adverse event presented as reversible autoimmune disease with rheumatological feature and pulmonary infiltrates COVID-19疫苗相关免疫不良事件表现为可逆性自身免疫性疾病，伴有风湿病特征和肺部浸润

Journal of Advanced Lung Health Pub Date : 2022-09-01 DOI: 10.4103/jalh.jalh_5_22

S. Patil, G. Narwade

{"title":"COVID-19 vaccine-related immunological adverse event presented as reversible autoimmune disease with rheumatological feature and pulmonary infiltrates","authors":"S. Patil, G. Narwade","doi":"10.4103/jalh.jalh_5_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_5_22","url":null,"abstract":"Rheumatological manifestation with acute febrile respiratory illness known to occur after coronavirus disease 2019 (COVID-19) pneumonia and presenting as long COVID disease, its occurrence with COVID vaccination is not very well associated or described in the literature. In this case report, a 45-year-old female presented with constitutional symptoms, persistent fever, and lung parenchymal infiltrates, without mycobacterial microscopic or genome documentation, received empirical antituberculosis (TB) treatment with the progression of disease with little clinical or radiological response. Bronchoscopy workup was inconclusive and tropical screen for bacterial, fungal, TB, and malignancy was negative. Vasculitis workup was inconclusive and rheumatological workup documented highly raised antinuclear antibodies titers. We have started her on steroid and hydroxychloroquine and clinical response documented with near-complete resolution of shadows in 12 weeks. Rheumatological syndrome which is a rare vaccine-related adverse event, reversible and easily treatable with routinely available medicines and importantly it is having excellent prognosis. Minimal systemic adverse events are known to occur with all viral vector vaccines, but its occurrence is rare and it should not impact on routine vaccinations as vaccination is a key step in this pandemic to protect humankind.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121026933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of obesity on respiratory health 肥胖对呼吸系统健康的影响

Journal of Advanced Lung Health Pub Date : 2022-09-01 DOI: 10.4103/jalh.jalh_25_22

Safreena Mohamed

引用次数: 0