International Journal of Biological and Pharmaceutical Sciences Archive最新文献_第8页

The effect of atorvastatin therapy on skeletal muscle function in hyperlipidemia patients in khartoum 阿托伐他汀治疗对喀土穆高脂血症患者骨骼肌功能的影响

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0081

Abdalla Eltoum Ali, Sitana Alkhwad Hassan Mohamed, Salma Abdallah Ali, Salih A Elmahdi

{"title":"The effect of atorvastatin therapy on skeletal muscle function in hyperlipidemia patients in khartoum","authors":"Abdalla Eltoum Ali, Sitana Alkhwad Hassan Mohamed, Salma Abdallah Ali, Salih A Elmahdi","doi":"10.53771/ijbpsa.2022.4.2.0081","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0081","url":null,"abstract":"Background: Atorvastatin is a lipid-lowering medication that causes skeletal muscle side effects by altering serum levels of skeletal muscle biomarkers. The aim of this study is to assess the effect of atorvastatin on muscle function and biomarker serum levels of CK, LDH, AST, Myoglobin, and Troponin I in Sudanese patients. Method: The total study group of hindered participants, including 60 case group (under Atorvastatin treatment) and 40 healthy as a control group, was matched with age and sex for the case group. The serum CK, LDH, myoglobin, and lipid profiles in the study groups were estimated by automated chemistry analyzers in this study. Result: Muscle pain was reported in case studies (55 = 91%). There was a significant increase in CK, LDH, and myoglobin among case studies when compared to the control group. The dose of drug showed no significant difference among the studied parameters. No correlation was found between CK and LDH with the duration of drug administration. Conclusion: Atorvastatin medication causes skeletal muscle pain among case study and increase muscle biomarkers such as CK, LDH, and myoglobin levels.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126724506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of antipsychotic drugs on fertility hormones in male patients – Khartoum state 抗精神病药物对男性患者生育激素的影响——喀土穆州

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0086

Abdalla Eltoum Ali, Lana Mohamed Babikir Aladani, Salih A Elmahd

{"title":"The influence of antipsychotic drugs on fertility hormones in male patients – Khartoum state","authors":"Abdalla Eltoum Ali, Lana Mohamed Babikir Aladani, Salih A Elmahd","doi":"10.53771/ijbpsa.2022.4.2.0086","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0086","url":null,"abstract":"Background: Psychiatric disorders are severe, depilating conditions with unknown a etiology and are commonly misdiagnosed when based solely on clinical interview. Antipsychotic drugs provide effective treatment of psychotic symptoms but might lead to neuroendocrine abnormalities. The study aim to assess fertility hormones Luteinizing and Testosterone among psychotic male patients at Khartoum State. Materials and Methods: A cross-sectional study was conducted during the period from July to August 2021, with fifty known diagnostic psychiatric patients as cases and fifty healthy people as case controls. The levels of serum testosterone and luteinizing hormones were measured by enzyme linked immune sorbent assay (ELISA). Results: The mean level of serum luteinizing hormone in psychiatric patients showed a significant decrease (3.8 0.54; P.value = 0.000) and the level of serum testosterone showed a significant increase (8.3 ± 0.92; P.value = 0.000) in psychiatric patients when compared to healthy individuals. There was a significant decrease in LH hormone in patients taking Olanzapine drugs compared to those taking Risperidone drugs (p value = 0.03). Conclusion: There were significant sexual dysfunctions in psychiatric patients due to antipsychotic drugs, which led to a decrease in luteinizing hormone and an increase in testosterone hormone.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131158618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical presentation and management of penetrating chest trauma 穿透性胸外伤的临床表现与治疗

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0082

Nripen Kumar Kundu, Sathi Dastider

{"title":"Clinical presentation and management of penetrating chest trauma","authors":"Nripen Kumar Kundu, Sathi Dastider","doi":"10.53771/ijbpsa.2022.4.2.0082","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0082","url":null,"abstract":"Thoracic injuries account for 20-25% of deaths due to trauma and contribute to 25-50% of the remaining deaths. Approximately 16,000 deaths per year in the United States alone are attributable to chest trauma. The present study was done in Dhaka Medical College Hospital from January 2004 to September 2005. This is one of the specialized Institutes of this country dealing with chest injury. In this series, 50 cases of penetrating chest injury were studied and 12 (Twelve) of them had also associated with blunt chest injury. The highest incidence occurred between the ages of 31 and 50 yrs. Male was predominantly affected by penetrating chest injury i.e. 84%. Homicidal injury was common in rural areas but accidental injury was common in urban area. Injuries by sharp weapon caused all of the homicidal injuries. In 28 cases (56%) showed penetrating chest injury with severe respiratory distress and rest 10 (20%) cases showed penetrating chest injury with hemorrhage from external wounds. Here, 70% cases are managed conservatively with or without I.C Tube drainage. Mean duration of Hospital stay for patient treated conservatively with or without 1C tube thoracostomy was 8 days but in patient with major surgery it was 15.5 days. Range of Hospital stay for conservatively treated patient was (3--8 days) and for patient with major surgery it was (10—16 days). Referred to other centers had due to extra--pulmonary Involvement, after initial resuscitation & I.C. tube thoracostomy. Mortality:-2% for penetrating chest injury.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133370710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of phytoconstituents and screening of antibacterial and antioxidant activity of different extracts from Moringa oleifera 辣木不同提取物的植物成分评价及抗菌抗氧化活性筛选

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0085

S. M. Al-Reza, Sinthia Khan, Kamrun Nahar, Jerin Alauddin, Shadiqul Islam

{"title":"Estimation of phytoconstituents and screening of antibacterial and antioxidant activity of different extracts from Moringa oleifera","authors":"S. M. Al-Reza, Sinthia Khan, Kamrun Nahar, Jerin Alauddin, Shadiqul Islam","doi":"10.53771/ijbpsa.2022.4.2.0085","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0085","url":null,"abstract":"The present study deals with the preliminary phytochemical screening and determination of antibacterial and antioxidant activity of various extracts from leaves and flowers of Moringa oleifera. The results revealed the presence of phenolic compounds, flavonoids, terpenoids, alkaloids, saponins, tannins and steroids in the extracts. All the extracts exhibited antibacterial effect against the tested bacteria with the diameter of inhibition zone ranging from 7 to 22 mm. However, highest antibacterial activity was observed by methanol and ethyl acetate extracts. The scavenging effect of the n-hexane extracts of leaf and flower on DPPH radicals increased with increasing concentration and highest activity was 70.94% and 73.50%, respectively while ascorbic acid was the highest DPPH radical scavenging activity (82.91%) at a concentration of 180 μg/ml. These results indicated that n-hexane extracts of flower and leaf of Moringa oleifera have a noticeable effect on scavenging free radical, however, it can be categorized as a good and potential antioxidant agent and could be one of the areas which attached a great deal of attention is the possible therapeutic potential of antioxidants in controlling degenerative diseases associated with marked oxidative damage. The preliminary studies on Moringa oleifera extracts exhibited their antibacterial and antioxidant potential which could be exploited further as future antimicrobials for pharmaceutical treatment, natural therapies, food preservation and cosmetic applications.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"220-223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127729724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delay in care seeking for menstrual regulation among the women attending a selected clinic 在选定诊所就诊的妇女中，因月经调节而寻求护理的时间延迟

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0083

Sathi Dastider

{"title":"Delay in care seeking for menstrual regulation among the women attending a selected clinic","authors":"Sathi Dastider","doi":"10.53771/ijbpsa.2022.4.2.0083","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0083","url":null,"abstract":"Each year women around the world experience 75 million unwanted pregnancies. Millions of women around the world risk their lives and health to end unwanted pregnancies. This descriptive type of cross-sectional study was conducted among 103 respondents from Mohammadpur Fertility Centre, Dhaka, Bangladesh to find out the factors influencing delay in care seeking for menstruation regulation among the women attending selected MR clinic from March to June 2015. Respondents were enrolled in the study using Purposive sampling technique. Data was collected by face to face interview with a semi-structured questionnaire. Here, 85% gave right answer about Knowing of MR. Respondent's main personal cause for delaying MR was that 37% home abortion by taking gynaecosid or other tablet. About familial causes of delaying MR shows that majority (47%) had in security of the house, 38% resistance by husband/others. The main social causes of delaying MR shows that majority (61%) was due to spiritual bindings and service or service center related causes for delaying MR due to treatment cost, male doctor, complexity of services and rest due to the substandard services. Women had good knowledge about MR and its timing even they make delay due to unawareness of their legal rights, personal, social and service related causes.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117352645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scoping review on impact of mosquito - borne diseases of man and animals and use of potential bacterial larvicidal agents to control mosquito vectors 蚊媒疾病对人类和动物的影响及潜在细菌杀幼虫剂的应用范围综述

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0088

Hemaladkshmi Padmanaban, Sahadiya Mandodan, Bhagyashree Bora, Manikandan Sivaprakasam, Abhisubesh Vijayakumar, Jibi Lukose, Aneha K, Kakhuangailiu Gangmei, Mathivanan Ashokkumar, Vijayalakshmi Krishnamoorthy, Subbiah Poopathi

{"title":"Scoping review on impact of mosquito - borne diseases of man and animals and use of potential bacterial larvicidal agents to control mosquito vectors","authors":"Hemaladkshmi Padmanaban, Sahadiya Mandodan, Bhagyashree Bora, Manikandan Sivaprakasam, Abhisubesh Vijayakumar, Jibi Lukose, Aneha K, Kakhuangailiu Gangmei, Mathivanan Ashokkumar, Vijayalakshmi Krishnamoorthy, Subbiah Poopathi","doi":"10.53771/ijbpsa.2022.4.2.0088","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0088","url":null,"abstract":"Mosquito vector-borne disease which accounts for the transmission of many deadly diseases like dengue, zika, chikungunya, Rift Valley fever, malaria, West Nile fever, heartworm, lumpy skin disease is one of the major causes of mortality, morbidity, and economic loss to human and animal communities. Though there have been several interventions like insecticide-treated nets, spatial repellents, indoor pesticide sprays to control adult mosquitoes, it only remains effective for short time, possibly leading to faster replacement of the adults by immature only achieving lesser mosquito population reduction. Extensive use of synthetic insecticides leads to resistance, affects non-target organisms and cause ecological imbalance. While recognizing the limitations of the synthetic and adulticide-based mosquito control methods, alternatively, microbial larvicidal agents are more feasible, target-specific, environment-friendly, low application rates, and moderate costs when compared with other vector control measures. This review highlights the microbial larvicidal agents as a most promising tool in vector control management to prevent disease transmission and discusses the major mosquito-borne diseases affecting humans and other animals.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127594265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post Covid-19 pulmonary fibrosis: A review article 新冠肺炎后肺纤维化:综述文章

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-09-30 DOI: 10.53771/ijbpsa.2022.4.1.0048

Dhwani Patel, Prutha Patel, Neel Raval, Jagdish Kakadiya

{"title":"Post Covid-19 pulmonary fibrosis: A review article","authors":"Dhwani Patel, Prutha Patel, Neel Raval, Jagdish Kakadiya","doi":"10.53771/ijbpsa.2022.4.1.0048","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.1.0048","url":null,"abstract":"COVID-19 also known as Coronavirus disease 2019 is an infectious disease caused by the highly contagious pathogen SARS-CoV-2.Various studies have found that 70–80% of patients who recovered from COVID-19 continue to have at least one or more symptoms even after being pronounced COVID-free. Pulmonary fibrosis is a severe respiratory illness consequence. It is defined by the lungs' failure to repair the injured alveolar epithelium, the persistence of fibroblasts, and the excessive deposition of collagen and other extracellular matrix components. An initial phase of lung injury is followed by acute inflammation and an effort at healing. Oxygen toxicity and ventilator-induced lung injury are two iatrogenic variables that may contribute to the fibrosis seen in survivors of severe COVID19 pneumonia. Based on scientific evidence and demographic findings, Pirfenidone and Nintedanib, used alone or in combination with anti-inflammatory agents and this combination is effective in preventing serious complications during COVID-19 infection. Pirfenidone inhibits TGF-β stimulated collagen synthesis and the synthesis of tumor necrosis factor, interferon-gamma, interleukin- 1beta, and interleukin-6 resulting in anti-inflammatory action. Depending on the concentration, pirfenidone has been demonstrated to have antioxidant capabilities. Nintedanib saw inhibitory action on pro-fibrotic mediators like platelet-derived growth factor and fibroblast growth factor, transforming growth factor-beta, and vascular endothelial growth factor. Who were already taking antifibrotic therapy saw a reduction in the number of acute exacerbations of IPF. Thus, Nintedanib and Pirfenidone both drugs slowed down the progression of Lung Fibrosis in patients over 18yr of age. However, more studies are required for usage of antifibrotics in Non- IPF patients.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"633 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115113770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of intermittent preventive treatment for malaria among pregnant women in a tertiary hospital in Northern part of Nigeria 对尼日利亚北部一家三级医院孕妇疟疾间歇预防治疗的评估

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-08-30 DOI: 10.53771/ijbpsa.2022.4.1.0079

Modupe Iretiola Builders, DANLAMI WETCOS DAYOM, STEPHEN AJEN ANZAKU, AKANDE TUNJI, Peter Uduak Ise

{"title":"Assessment of intermittent preventive treatment for malaria among pregnant women in a tertiary hospital in Northern part of Nigeria","authors":"Modupe Iretiola Builders, DANLAMI WETCOS DAYOM, STEPHEN AJEN ANZAKU, AKANDE TUNJI, Peter Uduak Ise","doi":"10.53771/ijbpsa.2022.4.1.0079","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.1.0079","url":null,"abstract":"The objective of this study is to assess the IPTp use among the pregnant women attending the antenatal clinic in Bingham University Teaching Hospital and improve the knowledge and attitudes of the patients toward the treatment. Method: A cross-sectional study was carried out between August and December 2017 among 107 pregnant women selected by systematic random sampling from antenatal care attendees at Bingham University Teaching Hospital in Jos North local Government of Plateau State of Nigeria. Information on the knowledge, attitudes and practices with respect to intermittent preventive treatment (IPTp) with sulphadoxine –pyrimethamine (SP) were obtained with the aid of a pre-tested interviewer-administered questionnaire. Descriptive statistics and Bivariate analysis were used to analyze the data. Results: Most of the interviewees were aged 26-30 years 40(37.4%) of the respondent, there was a high significant association between the age, educational level and occupation of the patients. Many of the respondents 57 (61%) were graduates, the association between the knowledge of malaria and level of education was highly significant. About 32 (29.9%) of the respondents had poor knowledge of treatment of malaria, there was a high significant association between the knowledge of treatment of malaria and level of education. 26 (24.3%) of the patients rarely used insecticide treated nets (ITNs) as method of malaria prevention, the association between the knowledge of malaria prevention and educational level was significant. Conclusion: Effort is needed to increase the sensitization of pregnant women about the benefits of IPTp in order to improve IPTp compliance.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"95 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132900902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation quality chicken meat during frozen storage 鸡肉冷冻贮藏质量评价

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-07-30 DOI: 10.53771/ijbpsa.2022.4.1.0074

Mussa M. Alkhatib, Mayada Fadil Mohmmad

引用次数: 0

Assessment of heavy metals in some edible fish species of the Komadugu-Yobe River, Gashua, Yobe State, North-East Nigeria: Threat to public health 尼日利亚东北部约贝州加舒亚komaduguu -Yobe河一些食用鱼类重金属评估:对公众健康的威胁

International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-07-30 DOI: 10.53771/ijbpsa.2022.4.1.0068

Lami Jafiya, S. Akogwu, Jibrin Sabo Suleimana, AA Osunlaja

{"title":"Assessment of heavy metals in some edible fish species of the Komadugu-Yobe River, Gashua, Yobe State, North-East Nigeria: Threat to public health","authors":"Lami Jafiya, S. Akogwu, Jibrin Sabo Suleimana, AA Osunlaja","doi":"10.53771/ijbpsa.2022.4.1.0068","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.1.0068","url":null,"abstract":"Contamination of Heavy metals in the aquatic environment has been a major challenge across the globe, due to the persistence of these metals and the tendency to accumulate in living organisms especially, fish species, which are important source of protein for most humans ‘consumption. In this study, the bio-accummulation of six metals (As, Cd, Cu, Ni, Pb and Zn) were analysed in three edible fish species (Oreochromis niloticus, Clariasgariepinus and Synodontisschall) sampled from the Komadugu-Yobe Riverusing Atomic Adsorption Spectrophotometry. The potential health threats for consumers were also assessed using standard indicators. Results showed that the mean concentration of heavy metals in the three fish species was in the following rank order: 22.23> 11.23 > 0.45> 2.56 >0.48> 2.33 > 0.05 for Zn >Ni >Cu >Pb >As >Cd, respectively. Zn recorded the highest concentration in both the gills and muscles of all the fishes at 11.28 mg/kg and 15.23 mg/kg, while 4 metals (Zn, Cd, Ni and Cu) out of 6 measured their highest concentrations in O. niloticus species. The remaining 2 metals (As and Pb) measured their highest levels in C. gareipinus. Furthermore, the highest concentrations of studied metals in the whole fish samples were lower than the maximum acceptable limits compared in this study. The potential human health indices associated with ingesting heavy metal indicated that HI (Hazard intake) and THQ (Target hazard quotient) values were below 1 implying that they pose no health threat, whereas EDI (Estimated Daily Intake) values of each metal were higher than the TDI (Tolerable daily intake) values indicating harmful effect on human health in daily consumption. Thus, constant monitoring and sustainable management of the Komadugu-Yobe River at Gashua is required to reduce the amount of contaminant entering the river which may pose a health threat to the inhabitants that feed on the contaminated fishes.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129045349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0