International Journal of Biological and Pharmaceutical Sciences Archive最新文献

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Perceived quality of antenatal care for pregnant women at a tertiary level hospital 对三级医院孕妇产前护理质量的感知
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-02-28 DOI: 10.53771/ijbpsa.2023.5.1.0105
Ranuara Khatun
{"title":"Perceived quality of antenatal care for pregnant women at a tertiary level hospital","authors":"Ranuara Khatun","doi":"10.53771/ijbpsa.2023.5.1.0105","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.1.0105","url":null,"abstract":"Introduction: Antenatal care (ANC) helps in the effective management of pre-natal morbidities, and facilitates institutional delivery and postpartum care, that can improve maternal and newborn health. Patient perceived quality is defined as the subjective and dynamic perception of the extent to which expected health care is received by a person and it provides excellent feedback to healthcare providers. Aim of the study: This study aimed to describe the perceived Quality of antenatal care for pregnant women at tertiary level hospitals in Bangladesh. Methods: A descriptive study was conducted among 98 pregnant women who were attending the antenatal care unit at OPD in Dhaka medical college hospital, Dhaka. A convenience sampling technique was used to select study participants. Data was collected through face-to-face interviews through a structured questionnaire. Data were analyzed by using frequencies, percentages, the mean and standard deviation to describe the demographic characteristic. Inferential statistics two-sample t-tests and ANOVA were used. Result: The mean age of pregnant mothers was 24.87(4.67) years, (ranging from 18 to 38). The total mean score quality of antenatal care was 3.77 ±.939. Only physical examination regarding fundal assessment rate was very poor (35.7%). There was a significant difference between education and perceived quality of antenatal care (F= 4.571, p = 013). Conclusion: The results revealed that those who had more education; had a more perceived quality of antenatal care and those who got more than four visits, had a good quality of antenatal care. The results provide baseline information for providing antenatal care to pregnant women about increasing the rate of physical assessment. The authentic assessment helps to reduce maternal and infant mortality and morbidity which can help in achieving the SDGs3.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128838531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cadres' activeness in following integrated healthcare center activities 干部对综合卫生保健中心活动的积极性
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-01-30 DOI: 10.53771/ijbpsa.2023.5.1.0014
Santalia Banne Tondok, Riska Sabrina, Asridawati Asridawati, Djusmadi Rasyid, Dian Meiliani Yulis, Masdarwati, Rahmat Pannyiwi, Rezqiqah Aulia Rahmat
{"title":"Cadres' activeness in following integrated healthcare center activities","authors":"Santalia Banne Tondok, Riska Sabrina, Asridawati Asridawati, Djusmadi Rasyid, Dian Meiliani Yulis, Masdarwati, Rahmat Pannyiwi, Rezqiqah Aulia Rahmat","doi":"10.53771/ijbpsa.2023.5.1.0014","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.1.0014","url":null,"abstract":"Integrated Healthcare Center is a community-based health vehicle that provides services for 5 main activities, namely Maternal and Child Health, Family Planning, Nutrition, Immunization and P2 Deare which are carried out from, by, for and with the community. The role of cadres is very important because cadres are responsible for implementing the Integrated Healthcare Center program. (Ministry of Health, RI 2018). This research method is a descriptive analytic with a cross-sectional study design, namely a research design designed to perform data analysis that frequently occurs or is ongoing in the study population, with a causal relationship model. The results of this study based on the level of knowledge of the respondents showed that out of 20 respondents, 15 people (75%) had good knowledge and 5 people (25%) had less knowledge. The discussion shows that based on the analysis it shows that the respondents who have good knowledge and good Integrated Healthcare Center cadres are active as many as 7 people (35%). While respondents who had good knowledge and less incidence of dermatitis were 4 people (20%). And the respondents who had less knowledge and active Integrated Healthcare Center cadres were as many as 4 people (20%). The results of statistical tests using the chi-Square test were p = 0.004 with a significance level of α = 0.05 which means p <0.05 then ha is accepted and ho is rejected, thus there is a relationship between knowledge and the activity of Integrated Healthcare Center cadres.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121387057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilization of mangrove peel (Xylocarpus granatum) extract as an active ingredient in the making of hand body lotion 利用红树果皮(Xylocarpus granatum)提取物作为有效成分制作护手身体乳
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-01-30 DOI: 10.53771/ijbpsa.2023.5.1.0012
Abdulrasyid Tolangara, Abdu Mas’ud, Sundari, Ningsi Saibi
{"title":"Utilization of mangrove peel (Xylocarpus granatum) extract as an active ingredient in the making of hand body lotion","authors":"Abdulrasyid Tolangara, Abdu Mas’ud, Sundari, Ningsi Saibi","doi":"10.53771/ijbpsa.2023.5.1.0012","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.1.0012","url":null,"abstract":"The fruit of Xylocarpus granatum has been used empirically by the community as a traditional medicine, the fruit peel is used as skin medicine. The results of the phytochemical analysis of Xylocarpus granatum rind simplex contain flavonoids, tannins, saponins, hydroquinones and steroids. This study aims to develop a hand body lotion product based on Xylocarpus granatum fruit peel extract. In this study, Xylocarus granatum fruit peel extract was formulated into a lotion preparation. Xylocarpus granatum fruit peel extract was prepared by maceration method using 70% ethanol solvent. The extract is formulated with a composition of 0.5 ml (FI). The lotion was then tested for its physical properties including pH, viscosity, homogeneity, spreadability and stability of color, odor and texture. The results showed that the lotion containing Xylocarpus granatum fruit peel extract was stored for 14 days for physical stability test. The results of the stability test showed that the lotion had a pH of 10.55, a viscosity of 1120000 mPas, the lotion did not change shape, smell, color, and did not cause skin irritation.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129220008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methods and problems in the transition of premature infants to oral feeding: A review of the literature 早产儿向口腔喂养过渡的方法及问题:文献综述
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2023-01-30 DOI: 10.53771/ijbpsa.2023.5.1.0106
Zaharoula Rigopoulou, Alexandros Mihopoulos, Pantelis Perdikaris
{"title":"Methods and problems in the transition of premature infants to oral feeding: A review of the literature","authors":"Zaharoula Rigopoulou, Alexandros Mihopoulos, Pantelis Perdikaris","doi":"10.53771/ijbpsa.2023.5.1.0106","DOIUrl":"https://doi.org/10.53771/ijbpsa.2023.5.1.0106","url":null,"abstract":"Introduction: Preterm infants are necessary to acquire safe and effective feeding skills as they are born without developed suck-swallow-respiration coordination skills. Various methods are used in premature infants in order to improve sucking skills and transit from gavage feeding to full oral feeding or breastfeeding safer and faster. Aim: To research and evaluate all methods by which a premature infant will transit to oral feeding, as well as to report problems that is going to happen during the transition. Methodology: A review of the literature was conducted in PubMed database from January 2022 to March 2022. The criteria for entering the review were the following: primary research studies, the language should be either English or Greek, the article should be published between 01/01/2012 to 31/12/2021 and studies that refer to preterm infants. The sort was done using the PRISMA 2009 method. Results: A search in electronic database PubMed, applying specific eligibility criteria, resulted in 159 articles. Through identification, screening and eligibility procedures, resulted in 20 articles. The methods that identified were nonnutritive sucking with either a pacifier, the mother’s breast, or a pacifier connected to a music player that heard the mother’s voice, oro-motor stimulation, a combination of nonnutritive sucking oro-motor stimulation, responsive feeding to neonatal signs, cup and probiotics. Conclusions: All these methods lead to earlier full oral feeding, reduce the length of hospital stay, and cause fewer side effects.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115090799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring trends, challenges and issues of blood donation in Yaounde-Cameroon 探讨雅温得-喀麦隆献血的趋势、挑战和问题
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-12-30 DOI: 10.53771/ijbpsa.2022.4.2.0095
Nguendo Yongsi H. Blaise
{"title":"Exploring trends, challenges and issues of blood donation in Yaounde-Cameroon","authors":"Nguendo Yongsi H. Blaise","doi":"10.53771/ijbpsa.2022.4.2.0095","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0095","url":null,"abstract":"Background: Access to a safe and adequate blood supply has proven to be challenging in sub-Saharan Africa, where systemic deficiencies have greatly been recorded. Blood availability is a public health issue of concern in Sub-Saharan Africa where both the demand and discard rates of blood are high and this includes Cameroon. Objective: This research study was carried out in order to capture the trends of blood donation, and to address the epidemiological aspects of blood donation in Yaounde. Study design and methods: The research was quantitative and relied on a cross-sectional study. With record base supplied by the National Blood Transfusion Center, as well as data from a random-sample survey of 300 blood donors at the Yaounde Central Hospitals’ blood bank. Statistical methods were applied to estimate national blood activities from January 2018 to September 2019, and the data subsequently analyzed using the Statistical Package for the Social Sciences (SPSS). Results: The results revealed a low frequency of blood donation, and portrayed that 81.3% of donors were first time donors. The majority of donors in our study were family/replacement (98.5%) while the minority voluntary (1.6%). More so, among the different aspects studied, five factors were found to be effectively associated to blood donation frequency namely: presence of tattoos/scarifications/piercings, the motivation underlying the blood donation, the blood group, the rhesus group and the occurrence of an accident during previous blood donations. Conclusion: Results could be useful to provide updates for the government and international organizations’ programs involved in the improvement of blood donor recruitment strategies in Cameroon. The outcome is to permit the elaboration of more effective strategies for recruiting and retaining voluntary regular blood donors and help move away from the use of replacement donors as the main source of blood, hence providing the population with safe blood and consequently reduce mortality rates linked to the availability and quality of blood.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124838238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of the effects of various locally-prepared agro-based carbons on the In vitro adsorption of cyanide using different activating agents 比较了不同活化剂对不同农基炭对氰化物体外吸附的影响
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-12-30 DOI: 10.53771/ijbpsa.2022.4.2.0100
Ofor Casimir Chijioke, Erejuwa Omotayo O, Akuodor Godwin Christian, Ramalan Mansur Aliyu, Aja Daniel Ogbonna, Ohanme Eugene Ohams, Shuneba Irene, Shu Elvis Neba
{"title":"A comparative study of the effects of various locally-prepared agro-based carbons on the In vitro adsorption of cyanide using different activating agents","authors":"Ofor Casimir Chijioke, Erejuwa Omotayo O, Akuodor Godwin Christian, Ramalan Mansur Aliyu, Aja Daniel Ogbonna, Ohanme Eugene Ohams, Shuneba Irene, Shu Elvis Neba","doi":"10.53771/ijbpsa.2022.4.2.0100","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0100","url":null,"abstract":"Aim: The study investigated the effect of using different activating agents- Nitric acid, Zinc chloride and Phosphoric acid on the adsorption of potassium cyanide by activated charcoal. We also investigated the In vitro effect of various doses of activated charcoal from different agro-based sources (Coconut shell, Rice husk, Castor oil seed shell, Edible clay and Plantain peels) on the adsorption of cyanide. Materials and methods: 50ml of 1M potassium cyanide was pipetted into two beakers for each sample of the prepared activated charcoal ranging from 0.5 g to 2.0 g. The resultant mixtures were agitated for 1 hour and allowed to stand for 24 hours at room temperature. The mixtures were filtered using whatman filter paper. The filtrates were analyzed for cyanide concentration using ninhydrin method and the absorbance read with ultraviolet-spectrophotometry. The absorbance was then converted to cyanide concentrations in mg/dl using standard cyanide concentrations graphs. Results: The results showed some statistically significant differences in the potassium cyanide adsorption by the different samples of prepared carbon materials activated with different activating agents except for coconut shell activated with zinc chloride. The cyanide adsorption was found to be in the same range for the activated charcoal samples prepared from different sources irrespective of the doses used in the experiment. Conclusion: The adsorptive capacities of different samples of activated charcoal varied significantly with the type of chemical activating agents used in the activation of the carbon. Coconut shell activated with HNO3 and H3P04 showed the best adsorption capacity. The cyanide adsorption by the locally-prepared activated charcoal was found to be better than that of the standard commercial activated charcoal.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131212518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of particle size of selected plant materials as protectants of stored Clarias gariepinus against Dermestes maculatus infestation 所选植物材料粒径对储存库中异色瓢虫防斑革螨侵害的效果研究
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-11-30 DOI: 10.53771/ijbpsa.2022.4.2.0089
Felix Olusegun Akinwumi, Kehinde Esther Olatunji, Amos Ayowumi Ademoroti
{"title":"Effectiveness of particle size of selected plant materials as protectants of stored Clarias gariepinus against Dermestes maculatus infestation","authors":"Felix Olusegun Akinwumi, Kehinde Esther Olatunji, Amos Ayowumi Ademoroti","doi":"10.53771/ijbpsa.2022.4.2.0089","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0089","url":null,"abstract":"The focus of this study was to determine the efficacy of the different particle sizes of the powder of three plant materials, African Nut-meg (Monodora myristica), Black pepper (Piper guineense) and dry bud of Cloves (Eugenia aromatica) in the control of Dermestes maculatus infestation on stored dried African mud catfish, Clarias gariepinus. Each plant material was pulverized, sieved into 0.5 mm and 0.4 mm particle-sizes, rubbed at 5 g of powder onto the body of 55 g dried fish and placed in Kilner jar in triplicates. The weight loss, adult / larvae emergence and adult mortality of treated fish were determined. The results showed that 0.4 mm particle size of the powder of P. guineense and E. aromatica prevented the infestation of D. maculatus as demonstrated by low fish weight loss, low level of adult / larvae emergence and high mean value of adult insect mortality. Higher number of larvae emergence and weight losses were recorded in the fish exposed to 0.5 mm of each plant powder and 0.4 mm of M. myristica. The study revealed that stored catfish could be treated with smooth particle sizes of Piper guineense and Eugenia aromatica, and can significantly serve as protectants of smoked C. gariepinus against Dermestes maculatus infestation.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126239856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internet addiction and psychological impact on adolescents: A scoping review 网络成瘾与青少年心理影响:范围综述
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-11-30 DOI: 10.53771/ijbpsa.2022.4.2.0096
Helen Dermani, Pantelis Perdikaris
{"title":"Internet addiction and psychological impact on adolescents: A scoping review","authors":"Helen Dermani, Pantelis Perdikaris","doi":"10.53771/ijbpsa.2022.4.2.0096","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0096","url":null,"abstract":"Background: Extensive engagement of young people with the internet can lead to the development of addictive behaviors. The purpose of this scoping review is to study the psychological effects of internet addiction on adolescents. Methods: The data were collected in three databases. The search retrieved 25 empirical studies that were divided into four categories: depression and anxiety, suicide, emotional and behavioral effects, school bullying and cyberbullying. The bibliography was searched based on a series of selection and exclusion criteria: a) articles of the last 5 years (2017-2022), b) articles that include primary empirical studies (quantitative and qualitative methodology), c) articles in which adolescents participate and d) articles published in Greek or the English language. The exclusion criteria were: a) articles that were meta-analyses, b) articles that did not present primary empirical findings (bibliographic reviews), c) articles that did not involve adolescents, d) case studies consisting of a small sample and e) articles that were published in a language other than English and Greek. Results: Searching for articles in the four databases led to the retrieving of 920 articles. The outcomes measured in this scoping review include 25 primary empirical studies. Conclusions: The review showed the aggravating role that internet addiction has in the manifestation of other forms of psychopathology in adolescents, the negative effects that cyber addiction has on the emotional state of adolescents, the effects that this form of addiction has on adolescent behavior and the psychological effects experienced by young people need to be taken seriously by professionals working with teens who are addicted to the internet","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125306757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthy lifestyle behaviors among field public health workers in a selected district of Sri Lanka 斯里兰卡选定地区现场公共卫生工作者的健康生活方式行为
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0092
Ubeysekara Nishani, Mallikarachchi Jayantha
{"title":"Healthy lifestyle behaviors among field public health workers in a selected district of Sri Lanka","authors":"Ubeysekara Nishani, Mallikarachchi Jayantha","doi":"10.53771/ijbpsa.2022.4.2.0092","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0092","url":null,"abstract":"Background: Healthy lifestyle behaviors: diet, physical activity and non-consumption of tobacco and alcohol of health workers are important as they engage in educating the community and people follow them as role models. Objective of this study was to describe the healthy lifestyle practices among field public health workers in one of the districts in Sri Lanka. Methods: Descriptive cross-sectional study was carried out in the Galle district. 303 Public Health Midwives (PHMs) were taken to the sample and Lifestyle practices were assessed using a pre-tested self-administered questionnaire. Results: Overweight and obesity prevalence were 24% and 3.7% respectively. None of them used tobacco or alcohol. Regular balance diet consumption was 57%. 18.2% have consumed 2 or >2 servings of fruit per day. The majority (49.2%) consumed vegetables 3 times per day and 21.8% consumed four or >4 servings per day. 43.6% consumed Sugar and sugar containing food daily. Only 12.2% preferred low-salt food. 21.8% of PHMs consumed oily foods few times a day. The majority (56.8%) of PHMs have engaged in recommended moderate physical activity but only 6.9% engaged in vigorous physical activity. The mean duration of walking time was 463 minutes per week. Conclusions and recommendations: Most lifestyle practices (Dietary and physical activity) are not very healthy among PHMs except for their alcohol and smoking behaviors. Public health workers should be motivated to spend healthy lifestyles by increasing awareness and incorporating healthy lifestyle promotion programs into their routine field work.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128819812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the hepatotoxic potential of methanol seed kernel extract of Mangifera indica (Mango) using rat mode 用大鼠模型评价芒果甲醇籽仁提取物的肝毒性
International Journal of Biological and Pharmaceutical Sciences Archive Pub Date : 2022-10-30 DOI: 10.53771/ijbpsa.2022.4.2.0084
Melford Uche Elendu, Chris Akunne Wariso, Amah Akuma Kalu, Ogwo Elisha Uko
{"title":"Evaluation of the hepatotoxic potential of methanol seed kernel extract of Mangifera indica (Mango) using rat mode","authors":"Melford Uche Elendu, Chris Akunne Wariso, Amah Akuma Kalu, Ogwo Elisha Uko","doi":"10.53771/ijbpsa.2022.4.2.0084","DOIUrl":"https://doi.org/10.53771/ijbpsa.2022.4.2.0084","url":null,"abstract":"The aim of this study was to evaluate the hepato-toxic potential of methanol seed kernel extract of Mangifera indica (mango). Dry mango seeds were broken to release the kernels which were subsequently dried at room temperature prior to grinding to fine powder. 500 g of powdered plant sample was developed into extract with the aid of a standard analytical procedure. Twenty (20) adult male albino rats divided into four (4) groups of five rats each. Group I (normal control) which was fed normal rat chow and water ad-libitum. Group II, III and IV were administered 100, 200 and 300 mg/kg of extract respectively for 21 days after which rats were sacrificed and blood sample collected and analysed for the activity of serum hepatomarkers ; Aspartate aminotransferase (AST), Alkaline phosphatase (ALP) and Alanine aminotransferase (ALT) was evaluated using standard procedures. Result obtained from the study showed that administration of 100 and 200 mg/kg bw did not increase the activity of the serum hepatomarkers. However, a contrary observation was made on the activity of serum hepatomarkers in rats administered with 400 mg/kg of MSKE inferring that methanol seed kernel extract of Mangifera indica (mango) could contain a hepatotoxic agent which can only elicit damage in large doses.","PeriodicalId":400966,"journal":{"name":"International Journal of Biological and Pharmaceutical Sciences Archive","volume":"423 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132864451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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