Zahmeeth Sakkaff, Jennie L. Catlett, Mikaela Cashman, M. Pierobon, Nicole R. Buan, Myra B. Cohen, C. Kelley
{"title":"End-to-end molecular communication channels in cell metabolism: an information theoretic study","authors":"Zahmeeth Sakkaff, Jennie L. Catlett, Mikaela Cashman, M. Pierobon, Nicole R. Buan, Myra B. Cohen, C. Kelley","doi":"10.1145/3109453.3109474","DOIUrl":"https://doi.org/10.1145/3109453.3109474","url":null,"abstract":"The opportunity to control and fine-tune the behavior of biological cells is a fascinating possibility for many diverse disciplines, ranging from medicine and ecology, to chemical industry and space exploration. While synthetic biology is providing novel tools to reprogram cell behavior from their genetic code, many challenges need to be solved before it can become a true engineering discipline, such as reliability, safety assurance, reproducibility and stability. This paper aims to understand the limits in the controllability of the behavior of a natural (non-engineered) biological cell. In particular, the focus is on cell metabolism, and its natural regulation mechanisms, and their ability to react and change according to the chemical characteristics of the external environment. To understand the aforementioned limits of this ability, molecular communication is used to abstract biological cells into a series of channels that propagate information on the chemical composition of the extracellular environment to the cell's behavior in terms of uptake and consumption of chemical compounds, and growth rate. This provides an information-theoretic framework to analyze the upper bound limit to the capacity of these channels to propagate information, which is based on a well-known and computationally efficient metabolic simulation technique. A numerical study is performed on two human gut microbes, where the upper bound is estimated for different environmental compounds, showing there is a potential for future practical applications.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130156643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prospects for the application of two-dimensional materials to terahertz-band communications","authors":"J. Bird, J. Jornet, E. Einarsson, G. Aizin","doi":"10.1145/3109453.3122845","DOIUrl":"https://doi.org/10.1145/3109453.3122845","url":null,"abstract":"In this paper, we review some of the key properties of emergent two-dimensional (2D) materials that make them potentially attractive for application in the hardware components needed to enable future communications in the terahertz (THz) band. Graphene is a material that has attracted enormous interest in recent years, due to its high electrical and thermal conductivities, and its capacity to exhibit pronounced and controlled plasmonic effects. Here we describe several schemes that seek to exploit these characteristics for the sourcing, manipulating, and detection of THz signals. Another class of 2D materials that are also promising for use in this area are the transition metal dichalcogenides (TMDs). These include materials such as MoS2 and WS2, which, like graphene, exhibit a multi-valley conduction band structure. In contrast to graphene, however, the valleys of TMDs are highly asymmetric, a characteristic that may allow the realization of novel high-frequency sources capable of THz operation.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115170337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance bounds of estimators in molecular communications under structural constraints","authors":"A. Sadeghi, S. Ghavami, G. Giannakis","doi":"10.1145/3109453.3109463","DOIUrl":"https://doi.org/10.1145/3109453.3109463","url":null,"abstract":"Parameter estimation is a key task in many aspects of communication systems including molecular communications (MC). The performance of parameter estimators involved in MC has been so far assessed using the Cramer-Rao lower bound (CRLB). However, for the discrete-amplitude parameters associated with the released \"information molecules\" in MC, pertinent regularity conditions do not hold, and consequently the CRLB does not exist. In this context, the present paper advocates the more general Hammersley-Chapman-Robinson lower bound (HCRLB), for MC parameter estimation. As a special case of practical importance, estimation of the number of released molecules, N, is investigated. A simple yet tight approximation of the HCRLB is developed by solving a non-convex optimization problem. A more accurate lower bound is also derived after accounting for the structural constraints inherent to the model under consideration. The resultant approach does not require the aforementioned regularity conditions to be satisfied.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121298071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","authors":"A. Davy, J. Federici","doi":"10.1145/3109453","DOIUrl":"https://doi.org/10.1145/3109453","url":null,"abstract":"NanoCom 2017 continues to be the premier venue for the latest advances in nanoscale computing and communication. The goals of the conference are to increase the visibility of this growing research area and to bring together researchers from diverse disciplines that can foster and develop new paradigms for nanoscale computing and communication. The inter-disciplinary conference attracts researchers from the fields of electrical and electronics engineering, computer science, biology, chemistry, physics, mathematics, bioengineering, biotechnology, materials science, and nanotechnology.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"548 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116232273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. I. Ansari, C. Chrysostomou, Taqwa Saeed, M. Lestas, A. Pitsillides
{"title":"Received signal strength for randomly distributed molecular nanonodes","authors":"R. I. Ansari, C. Chrysostomou, Taqwa Saeed, M. Lestas, A. Pitsillides","doi":"10.1145/3109453.3109466","DOIUrl":"https://doi.org/10.1145/3109453.3109466","url":null,"abstract":"We consider nanonodes randomly distributed in a circular area and characterize the received signal strength when a pair of these nodes employ molecular communication. Two communication methods are investigated, namely free diffusion and diffusion with drift. Since the nodes are randomly distributed, the distance between them can be represented as a random variable, which results in a stochastic process representation of the received signal strength. We derive the probability density function of this process for both molecular communication methods. Specifically for the case of free diffusion we also derive the cumulative distribution function, which can be used to derive transmission success probabilities. The presented work constitutes a first step towards the characterization of the signal to noise ratio in the considered setting for a number of molecular communication methods.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128053807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haoyang Zhai, T. Nakano, A. Vasilakos, Kun Yang, Qiang Liu
{"title":"Increase detection algorithm for concentration-encoded diffusion-based molecular communication","authors":"Haoyang Zhai, T. Nakano, A. Vasilakos, Kun Yang, Qiang Liu","doi":"10.1145/3109453.3109465","DOIUrl":"https://doi.org/10.1145/3109453.3109465","url":null,"abstract":"In this paper, we propose a demodulation technique, the increase detection algorithm (IDA), to improve the reliability of concentration-encoded diffusion-based molecular communication. The proposed demodulation technique detects an increase (i.e., a relative concentration value) in molecule concentration to demodulate information as opposed to detecting an absolute concentration value. We evaluate the proposed demodulation technique in terms of bit error rate (BER) and demonstrate that the proposed demodulation technique successfully isolates ISI from concentration-encoded diffusion-based molecular communication to achieve a lower BER than a commonly used demodulation technique.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115520056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Rodríguez-Vázquez, J. Grzyb, N. Sarmah, U. Pfeiffer, B. Heinemann
{"title":"Towards THz high data-rate communication: a 50 Gbps all-electronic wireless link at 240 GHz","authors":"Pedro Rodríguez-Vázquez, J. Grzyb, N. Sarmah, U. Pfeiffer, B. Heinemann","doi":"10.1145/3109453.3122842","DOIUrl":"https://doi.org/10.1145/3109453.3122842","url":null,"abstract":"This paper presents a fully-integrated direct-conversion quadrature transmitter and receiver implemented in a SiGe HBT technology with fT/fmax=350/550 GHz working at a carrier frequency of 240 GHz. The transmitter has a 3-dB RF/LO bandwidth of 35 GHz with a peak output power of 8.5 dBm, while the receiver presents 22 GHz of RF/LO 3-dB bandwidth with peak conversion gain of 21 dB and a single side band (SSB) noise figure of 9.5 dB. Each of the modules is implemented in a single silicon chip, including a broadband silicon lens-integrated on-chip antenna, and assembled on a low-cost high-speed PCB with a recess to accommodate the chip and wire-bonding compensation structures. This results in an IF bandwidth of 13 GHz at the board-connector level. The preliminary wireless-link test for a distance of 1 m has demonstrated data-rates of 30 Gbps with an EVM of 26% and 50 Gbps with an EVM of 29% for BPSK and QPSK modulation respectively, without applying any channel equalization or error correction techniques.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129471264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Felicetti, M. Femminella, Todor Ivanov, P. Lio’, G. Reali
{"title":"A big-data layered architecture for analyzing molecular communications systems in blood vessels","authors":"L. Felicetti, M. Femminella, Todor Ivanov, P. Lio’, G. Reali","doi":"10.1145/3109453.3109468","DOIUrl":"https://doi.org/10.1145/3109453.3109468","url":null,"abstract":"We present a novel architecture for analyzing molecular communications systems in blood vessels for drug delivery and monitoring. This architecture leverages a big data platform for simultaneously using data produced by the existing simulation platforms, health records, and medical data acquisition systems. An included machine learning engine may provide useful insight for medical purposes.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117144518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afsaneh Gharouni-Chamansabz, Anamaria Moldovan, W. Gerstacker
{"title":"Performance comparison of equalization techniques for indoor THz communications","authors":"Afsaneh Gharouni-Chamansabz, Anamaria Moldovan, W. Gerstacker","doi":"10.1145/3109453.3109464","DOIUrl":"https://doi.org/10.1145/3109453.3109464","url":null,"abstract":"THz communications is one of the candidates for future ultra-fast wireless transmission. However, the peculiarities of propagation in the THz band result in a highly frequency-selective channel and a much longer channel impulse response (CIR) compared to that of a wireless microwave channel. In this paper, an indoor single-carrier THz transmission is studied. To this end, the following equalization approaches are considered: Tomlinson-Harashima precoding (THP), a waveform design with interference management for time-reversal signaling, and an iterative algorithm with adaptive soft feedback. The iterative algorithm was originally designed for binary transmission and is extended to QAM modulation. A common framework is developed to compare the performance of the different equalization methods. Simulation results support the feasibility of the investigated equalization schemes for coping with the frequency selectivity of the THz band in an indoor environment.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"499 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116287100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Power-efficient terahertz communication circuits","authors":"Hamidreza Aghasi, E. Afshari","doi":"10.1145/3109453.3122844","DOIUrl":"https://doi.org/10.1145/3109453.3122844","url":null,"abstract":"Recent advances in CMOS/BiCMOS technologies have an enormous impact on the demonstration of mm-wave and terahertz integrated circuits. The higher frequency of operation at these ranges compared to RF frequencies, is specifically important for design of high speed communication systems. In this paper, we review the design challenges and recent demonstrations of communication circuits at the terahertz band. In order to achieve an efficient power generation in terahertz oscillators, a return-path gap coupler structure is introduced. Based on this structure, a 220 GHz spatial-orthogonal ASK transmitter is designed in 130 nm SiGe BiCMOS technology. This transmitter achieves an EIRP of 21 dBm and DC-to-THz-radiation efficiency of 0.7%. Compared with the state-of-the-art terahertz communication circuits, this circuit achieves a higher output power and higher DC-to-RF efficiency1.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124818047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}