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Therapeutic Targeting of the Tumor Microenvironment最新文献

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Abstract P044: Real-time visualization of tumor cell phenotype and microenvironmental heterogeneity enabled by a hyperspectral fluorescence microendoscope P044:利用高光谱荧光显微内窥镜实现肿瘤细胞表型和微环境异质性的实时可视化
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p044
M. A. Saad, Bryan Q. Spring, A. Palanisami, Eric M. Kercher, Ryan T. Lang, J. Sutin, Zhiming Mai, T. Hasan
{"title":"Abstract P044: Real-time visualization of tumor cell phenotype and microenvironmental heterogeneity enabled by a hyperspectral fluorescence microendoscope","authors":"M. A. Saad, Bryan Q. Spring, A. Palanisami, Eric M. Kercher, Ryan T. Lang, J. Sutin, Zhiming Mai, T. Hasan","doi":"10.1158/2326-6074.tumimm21-p044","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p044","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125103527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P040: Harness the immune-modulatory activities of Toxoplasma gondii to improve lymphocyte infiltration into brain tumors 摘要:利用弓形虫免疫调节活性促进淋巴细胞浸润脑肿瘤
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p040
Y. Nguyen, Xiaoyu Zhao, Sarah E. Ewald, T. Harris, H. Zong
{"title":"Abstract P040: Harness the immune-modulatory activities of Toxoplasma gondii to improve lymphocyte infiltration into brain tumors","authors":"Y. Nguyen, Xiaoyu Zhao, Sarah E. Ewald, T. Harris, H. Zong","doi":"10.1158/2326-6074.tumimm21-p040","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p040","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"232 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121297638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P039: The immune profile of colorectal and pancreas adenocarcinomas: Differences between central and peripheric tumor regions 摘要P039:结直肠癌和胰腺腺癌的免疫谱:中心和外周肿瘤区域的差异
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p039
A. Maia, Joana R Lérias, L. Borrego, M. Castillo-Martin, M. Maeurer
{"title":"Abstract P039: The immune profile of colorectal and pancreas adenocarcinomas: Differences between central and peripheric tumor regions","authors":"A. Maia, Joana R Lérias, L. Borrego, M. Castillo-Martin, M. Maeurer","doi":"10.1158/2326-6074.tumimm21-p039","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p039","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128367277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract IA16: Immune suppression in cancer and strategies for its reversal [摘要]癌症中的免疫抑制及其逆转策略
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-ia16
R. N. Kaplan
{"title":"Abstract IA16: Immune suppression in cancer and strategies for its reversal","authors":"R. N. Kaplan","doi":"10.1158/2326-6074.tumimm21-ia16","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-ia16","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121586675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P031: Enrichment of photodynamically-primed anti-tumor immune infiltrates in pancreatic cancer: Enabling enhanced immunotherapy P031:胰腺癌中光动力引发的抗肿瘤免疫浸润的富集:增强免疫治疗
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p031
P. De Silva, M. A. Saad, Zhiming Mai, S. Bano, A. P. Camargo, T. Hasan
{"title":"Abstract P031: Enrichment of photodynamically-primed anti-tumor immune infiltrates in pancreatic cancer: Enabling enhanced immunotherapy","authors":"P. De Silva, M. A. Saad, Zhiming Mai, S. Bano, A. P. Camargo, T. Hasan","doi":"10.1158/2326-6074.tumimm21-p031","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p031","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115117358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P033: Bone microenvironment-suppressed T cells increase osteoclast formation and the development of osteolytic bone metastases in mice 摘要P033:骨微环境抑制T细胞增加小鼠破骨细胞形成和溶骨转移的发展
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p033
Danna L. Arellano, Patricia Juárez, Paloma S. Almeida-Luna, Felipe Olvera, S. Jiménez, Pierrick G J Fournier
{"title":"Abstract P033: Bone microenvironment-suppressed T cells increase osteoclast formation and the development of osteolytic bone metastases in mice","authors":"Danna L. Arellano, Patricia Juárez, Paloma S. Almeida-Luna, Felipe Olvera, S. Jiménez, Pierrick G J Fournier","doi":"10.1158/2326-6074.tumimm21-p033","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p033","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124362801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P050: Oncogenic kinase therapy restricts CD8 T cell differentiation and clonal expansion P050:致瘤激酶治疗限制CD8 T细胞分化和克隆扩增
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p050
Andrew D Tieniber, A. Hanna, Benjamin D Medina, Kevin J Do, Lillian Levin, Ferdiando Rossi, R. DeMatteo
{"title":"Abstract P050: Oncogenic kinase therapy restricts CD8 T cell differentiation and clonal expansion","authors":"Andrew D Tieniber, A. Hanna, Benjamin D Medina, Kevin J Do, Lillian Levin, Ferdiando Rossi, R. DeMatteo","doi":"10.1158/2326-6074.tumimm21-p050","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p050","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129035887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract P052: Functional ADORA2A antibodies demonstrates the antagonistic and tumor suppression activities 摘要P052:功能性ADORA2A抗体显示出拮抗和肿瘤抑制活性
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p052
Linya Wang, Ana Lujan, Eric Kwan, Crystal Safavi, Mouna Villalta, Tom Z. Yuan, Melina Mathur, Joyce Lai, H. Giang, Qiang Liu, F. Axelrod, A. Sato
{"title":"Abstract P052: Functional ADORA2A antibodies demonstrates the antagonistic and tumor suppression activities","authors":"Linya Wang, Ana Lujan, Eric Kwan, Crystal Safavi, Mouna Villalta, Tom Z. Yuan, Melina Mathur, Joyce Lai, H. Giang, Qiang Liu, F. Axelrod, A. Sato","doi":"10.1158/2326-6074.tumimm21-p052","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p052","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"71 1-3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123472514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P045: Preclinical transcriptome-based evaluation of the translatable potential of new treatments in Triple-Negative Breast Cancer P045:基于临床前转录组的三阴性乳腺癌新疗法可翻译潜力评估
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p045
Ammar Salkini
{"title":"Abstract P045: Preclinical transcriptome-based evaluation of the translatable potential of new treatments in Triple-Negative Breast Cancer","authors":"Ammar Salkini","doi":"10.1158/2326-6074.tumimm21-p045","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p045","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122213459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P025: Uncovering molecular actors of IDO-mediated T cell dysfunction with genome-wide CRISPR/Cas9 knockout screens P025:利用全基因组CRISPR/Cas9敲除筛选揭示ido介导的T细胞功能障碍的分子因素
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p025
Raphaële Bombart, Jingjing Zhu, B. J. Van den Eynde
{"title":"Abstract P025: Uncovering molecular actors of IDO-mediated T cell dysfunction with genome-wide CRISPR/Cas9 knockout screens","authors":"Raphaële Bombart, Jingjing Zhu, B. J. Van den Eynde","doi":"10.1158/2326-6074.tumimm21-p025","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p025","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134335131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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