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Therapeutic Targeting of the Tumor Microenvironment最新文献

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Abstract PR02: The co-expression of VISTA and TIGIT on cytotoxic T cells defines subpopulation with altered immunometabolism 摘要/ Abstract摘要:VISTA和TIGIT在细胞毒性T细胞上的共同表达定义了免疫代谢改变的亚群
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-pr02
C. Gilmour, S. Yoo, T. Chan, Lily Wang
{"title":"Abstract PR02: The co-expression of VISTA and TIGIT on cytotoxic T cells defines subpopulation with altered immunometabolism","authors":"C. Gilmour, S. Yoo, T. Chan, Lily Wang","doi":"10.1158/2326-6074.tumimm21-pr02","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-pr02","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134171632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P051: Function of shp-1 and shp-2 phosphatases in T cell-mediated anti-tumor response P051: shp-1和shp-2磷酸酶在T细胞介导的抗肿瘤反应中的作用
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p051
P. Ventura, Milica Gakovic, Berenice Fischer, Sarah Thomson, H. J. Khameneh, A. Zenobi, G. Rota, É. Vivier, W. Birchmeier, D. Cantrell, G. Guarda
{"title":"Abstract P051: Function of shp-1 and shp-2 phosphatases in T cell-mediated anti-tumor response","authors":"P. Ventura, Milica Gakovic, Berenice Fischer, Sarah Thomson, H. J. Khameneh, A. Zenobi, G. Rota, É. Vivier, W. Birchmeier, D. Cantrell, G. Guarda","doi":"10.1158/2326-6074.tumimm21-p051","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p051","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122347337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P028: Effects of histone deacetylase inhibition on major histocompatibility compatibility complex (MHC) class I expression, growth, and migration of cancer cells P028:组蛋白去乙酰化酶抑制对肿瘤细胞主要组织相容性相容性复合体(MHC) I类表达、生长和迁移的影响
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p028
S. Knoche, Gabrielle L. Brumfield, Benjamin T. Goetz, Bailee H Sliker, Cecilia Barbosa, S. Romanova, T. Bronich, D. Coulter, J. Solheim
{"title":"Abstract P028: Effects of histone deacetylase inhibition on major histocompatibility compatibility complex (MHC) class I expression, growth, and migration of cancer cells","authors":"S. Knoche, Gabrielle L. Brumfield, Benjamin T. Goetz, Bailee H Sliker, Cecilia Barbosa, S. Romanova, T. Bronich, D. Coulter, J. Solheim","doi":"10.1158/2326-6074.tumimm21-p028","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p028","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125388554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P034: Tumor-targeted interleukin-12 and Entinostat combination therapy improves cancer survival by reprogramming the tumor immune cell landscape 肿瘤靶向白介素-12和恩替诺他联合治疗通过重新编程肿瘤免疫细胞景观来提高癌症生存率
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p034
Kristin C Hicks, Paul L. Chariou, Y. Ozawa, Christine M Minnar, Karin M. Knudson, T. Meyer, Jing Bian, M. Cam, J. Schlom, Sofia R. Gameiro
{"title":"Abstract P034: Tumor-targeted interleukin-12 and Entinostat combination therapy improves cancer survival by reprogramming the tumor immune cell landscape","authors":"Kristin C Hicks, Paul L. Chariou, Y. Ozawa, Christine M Minnar, Karin M. Knudson, T. Meyer, Jing Bian, M. Cam, J. Schlom, Sofia R. Gameiro","doi":"10.1158/2326-6074.tumimm21-p034","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p034","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115529699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P048: Steatosis promote liver cancer development by inducing chemokine production from Kupffer cells 摘要P048:脂肪变性通过诱导Kupffer细胞产生趋化因子促进肝癌的发展
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p048
B. Stiles, Taojian Tu, Lina He, Mario M. Alba
{"title":"Abstract P048: Steatosis promote liver cancer development by inducing chemokine production from Kupffer cells","authors":"B. Stiles, Taojian Tu, Lina He, Mario M. Alba","doi":"10.1158/2326-6074.tumimm21-p048","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p048","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"194 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116468902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P038: Identification and functional evaluation of monoclonal antibodies specifically targeting human Carbonic Anhydrase IX P038:人碳酸酐酶IX特异性单克隆抗体的鉴定及功能评价
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p038
A. Lenferink, J. Baardsnes, T. Sulea, Cunle Wu, Maurizio Acchione, M. Jaramillo, P. McDonald, F. Bénard, S. Dedhar
{"title":"Abstract P038: Identification and functional evaluation of monoclonal antibodies specifically targeting human Carbonic Anhydrase IX","authors":"A. Lenferink, J. Baardsnes, T. Sulea, Cunle Wu, Maurizio Acchione, M. Jaramillo, P. McDonald, F. Bénard, S. Dedhar","doi":"10.1158/2326-6074.tumimm21-p038","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p038","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126438495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P030: Making cold tumors hot: Multi-faceted immune ignition by USP6 P030:使冷肿瘤变热:USP6的多方位免疫点火
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p030
I. Henrich, Kanika Jain, Laura Quick, R. Young, M. Chou
{"title":"Abstract P030: Making cold tumors hot: Multi-faceted immune ignition by USP6","authors":"I. Henrich, Kanika Jain, Laura Quick, R. Young, M. Chou","doi":"10.1158/2326-6074.tumimm21-p030","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p030","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128424489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P024: Using innate immune ligands to activate adaptive immune cells for glioblastoma therapy 摘要:利用先天免疫配体激活适应性免疫细胞治疗胶质母细胞瘤
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p024
Richard Baugh, H. Khalique, Janet Lei-Rossmann, L. Seymour
{"title":"Abstract P024: Using innate immune ligands to activate adaptive immune cells for glioblastoma therapy","authors":"Richard Baugh, H. Khalique, Janet Lei-Rossmann, L. Seymour","doi":"10.1158/2326-6074.tumimm21-p024","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p024","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132706089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P049: ONM-501 ― A synthetic polyvalent STING agonist for cancer immunotherapy ONM-501 -一种用于肿瘤免疫治疗的合成多价STING激动剂
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p049
Suxin Li, Min Luo, Zhaohui Wang, Q. Feng, Jonathan Wilhelm, Xu Wang, Wei Li, Jian Wang, Q. Su, G. Bharadwaj, Jason B. Miller, Katy Torres, Stephen Gutowski, Agnieszka Cholka, Yangjie Fu, T. Zhao, B. Sumer, Hongtao Yu, Jinming Gao
{"title":"Abstract P049: ONM-501 ― A synthetic polyvalent STING agonist for cancer immunotherapy","authors":"Suxin Li, Min Luo, Zhaohui Wang, Q. Feng, Jonathan Wilhelm, Xu Wang, Wei Li, Jian Wang, Q. Su, G. Bharadwaj, Jason B. Miller, Katy Torres, Stephen Gutowski, Agnieszka Cholka, Yangjie Fu, T. Zhao, B. Sumer, Hongtao Yu, Jinming Gao","doi":"10.1158/2326-6074.tumimm21-p049","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p049","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"247 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133095917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Abstract P035: A promising cancer immunotherapy target: Novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27 P035:一个有前景的癌症免疫治疗靶点:针对人t细胞共刺激受体CD27的新型全人激动剂抗体
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p035
Y. Ovechkina, S. Sridhar, D. Jurchen, D. Peckham, E. Tarcha, S. Iadonato, T. Guillaudeux
{"title":"Abstract P035: A promising cancer immunotherapy target: Novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27","authors":"Y. Ovechkina, S. Sridhar, D. Jurchen, D. Peckham, E. Tarcha, S. Iadonato, T. Guillaudeux","doi":"10.1158/2326-6074.tumimm21-p035","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p035","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122299105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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