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Therapeutic Targeting of the Tumor Microenvironment最新文献

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Abstract P037: Interleukin-10 is a dominant and reversible mechanism of immune evasion in human colorectal cancer liver metastasis 摘要白介素-10是人类结直肠癌肝转移中免疫逃避的显性可逆机制
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p037
Teresa S. Kim, K. Sullivan, Xiu-yun Jiang, Cynthia Hsu, K. Labadie, Karan Kohli, H. Kenerson, Sara K Daniel, Arezou Abbasi, R. Yeung, V. Pillarisetty
{"title":"Abstract P037: Interleukin-10 is a dominant and reversible mechanism of immune evasion in human colorectal cancer liver metastasis","authors":"Teresa S. Kim, K. Sullivan, Xiu-yun Jiang, Cynthia Hsu, K. Labadie, Karan Kohli, H. Kenerson, Sara K Daniel, Arezou Abbasi, R. Yeung, V. Pillarisetty","doi":"10.1158/2326-6074.tumimm21-p037","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p037","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128348614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P042: Chemokine dysregulation creates the immunosuppressive tumor microenvironment and promotes human papillomavirus-associated head and neck cancer 趋化因子失调产生免疫抑制肿瘤微环境，促进人乳头瘤病毒相关头颈癌的发生
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p042
D. Vermeer, J. Westrich, P. Colbert, C. Welbon, John H. Lee, D. Raben, W. Spanos, D. Pyeon
{"title":"Abstract P042: Chemokine dysregulation creates the immunosuppressive tumor microenvironment and promotes human papillomavirus-associated head and neck cancer","authors":"D. Vermeer, J. Westrich, P. Colbert, C. Welbon, John H. Lee, D. Raben, W. Spanos, D. Pyeon","doi":"10.1158/2326-6074.tumimm21-p042","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p042","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"360 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134324541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract P027: Extending intratumoral therapeutic durability using a multivalent immunotherapy platform P027:利用多价免疫治疗平台延长肿瘤内治疗的持久性
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p027
L. Brier, M. Mahomed, Amy A. Twite, Adam Barnebey, W. Jackson
{"title":"Abstract P027: Extending intratumoral therapeutic durability using a multivalent immunotherapy platform","authors":"L. Brier, M. Mahomed, Amy A. Twite, Adam Barnebey, W. Jackson","doi":"10.1158/2326-6074.tumimm21-p027","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p027","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114529111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P047: Inactivation of IFN signaling drive immunosuppressive MDSC function and can be therapeutically targeted P047: IFN信号失活驱动免疫抑制MDSC功能，可以靶向治疗
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p047
E. Sanseviero, Kevin Alicea-Torres, Yulia Nefedova, S. Fuchs, D. Gabrilovich
{"title":"Abstract P047: Inactivation of IFN signaling drive immunosuppressive MDSC function and can be therapeutically targeted","authors":"E. Sanseviero, Kevin Alicea-Torres, Yulia Nefedova, S. Fuchs, D. Gabrilovich","doi":"10.1158/2326-6074.tumimm21-p047","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p047","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122228616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P029: Expression of galectin-3 and pro-inflammatory cytokines in gliomas: Implications and therapeutic potential P029:半乳糖凝集素-3和促炎细胞因子在胶质瘤中的表达:意义和治疗潜力
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p029
John L. Caniglia
{"title":"Abstract P029: Expression of galectin-3 and pro-inflammatory cytokines in gliomas: Implications and therapeutic potential","authors":"John L. Caniglia","doi":"10.1158/2326-6074.tumimm21-p029","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p029","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115152931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract IA15: Targeting tumor associated macrophages for anti-cancer therapy IA15:靶向肿瘤相关巨噬细胞进行抗癌治疗
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-ia15
Jennifer L. Guerriero
{"title":"Abstract IA15: Targeting tumor associated macrophages for anti-cancer therapy","authors":"Jennifer L. Guerriero","doi":"10.1158/2326-6074.tumimm21-ia15","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-ia15","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115194494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P041: Simultaneous checkpoint inhibition and immune cell activation that is safely localized to solid tumors P041:同时检查点抑制和免疫细胞激活安全定位于实体肿瘤
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p041
Richard A. Richieri, N. Narula, Cindy Loomis, V. Mezzano, John Billimek, Glenn T. Reynolds, C. Reutelingsperger, A. Zijlstra, M. Parseghian
{"title":"Abstract P041: Simultaneous checkpoint inhibition and immune cell activation that is safely localized to solid tumors","authors":"Richard A. Richieri, N. Narula, Cindy Loomis, V. Mezzano, John Billimek, Glenn T. Reynolds, C. Reutelingsperger, A. Zijlstra, M. Parseghian","doi":"10.1158/2326-6074.tumimm21-p041","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p041","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132658999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P026: Uncovering mechanisms of immune evasion in a novel immunogenic model of KRAS-mutant lung cancer P026:揭示kras突变肺癌免疫原性新模型的免疫逃避机制
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p026
J. Boumelha, S. de Carné, Pablo Romero, Miriam Moliona, J. Downward
{"title":"Abstract P026: Uncovering mechanisms of immune evasion in a novel immunogenic model of KRAS-mutant lung cancer","authors":"J. Boumelha, S. de Carné, Pablo Romero, Miriam Moliona, J. Downward","doi":"10.1158/2326-6074.tumimm21-p026","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p026","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133743259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P036: A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs P036:结肠癌细胞对小分子肿瘤药物反应的高通量定制细胞激酶筛选
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p036
K. Huntington, Anna D Louie, Lanlan Zhou, W. El-Deiry
{"title":"Abstract P036: A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs","authors":"K. Huntington, Anna D Louie, Lanlan Zhou, W. El-Deiry","doi":"10.1158/2326-6074.tumimm21-p036","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p036","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131177224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P053: Ablation of CCR1 relieves immunosuppression in pancreatic cancer P053:消融CCR1可缓解胰腺癌的免疫抑制
Therapeutic Targeting of the Tumor Microenvironment Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p053
Yaqing Zhang, Kristee L Brown, Wei Yan, Z. Nwosu, Eileen Carpenter, Katelyn L. Donahue, Ashley Velez-Delgado, Sion Yang, M. Pasca di Magliano
{"title":"Abstract P053: Ablation of CCR1 relieves immunosuppression in pancreatic cancer","authors":"Yaqing Zhang, Kristee L Brown, Wei Yan, Z. Nwosu, Eileen Carpenter, Katelyn L. Donahue, Ashley Velez-Delgado, Sion Yang, M. Pasca di Magliano","doi":"10.1158/2326-6074.tumimm21-p053","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p053","url":null,"abstract":"","PeriodicalId":399403,"journal":{"name":"Therapeutic Targeting of the Tumor Microenvironment","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133895848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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