Recent Results in Cancer Research最新文献

筛选
英文 中文
Palliative Care in Cholangiocarcinoma. 胆管癌的姑息治疗。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_9
Attakorn Raksasataya, Anucha Ahooja, Vivian Krangbunkrong, Apiwat Jareanrat, Attapol Titapun, Narong Khuntikeo
{"title":"Palliative Care in Cholangiocarcinoma.","authors":"Attakorn Raksasataya,&nbsp;Anucha Ahooja,&nbsp;Vivian Krangbunkrong,&nbsp;Apiwat Jareanrat,&nbsp;Attapol Titapun,&nbsp;Narong Khuntikeo","doi":"10.1007/978-3-031-35166-2_9","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_9","url":null,"abstract":"<p><p>This chapter details all aspects of the general principles of palliative care for advanced stage cholangiocarcinoma patients. These include symptoms management, communication guide, advance care planning, and management for bereavement. Surgical and intervention techniques of palliative biliary drainage are described in detail for patients with obstructive jaundice with advanced stage CCA. Additionally, details are provided regarding the establishment of a multidisciplinary palliative care team which is critical to provide the most appropriate multimodal treatment for good quality of life and survival of patients.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"245-267"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
RAW ATTITUDES: Socio-Cultures, Altered Landscapes, and Changing Perceptions of an Underestimated Disease. 原始的态度:社会文化、改变的景观和对一种被低估的疾病不断变化的看法。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_11
Carl Grundy-Warr, Ross H Andrews, Narong Khuntikeo, Trevor N Petney
{"title":"RAW ATTITUDES: Socio-Cultures, Altered Landscapes, and Changing Perceptions of an Underestimated Disease.","authors":"Carl Grundy-Warr,&nbsp;Ross H Andrews,&nbsp;Narong Khuntikeo,&nbsp;Trevor N Petney","doi":"10.1007/978-3-031-35166-2_11","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_11","url":null,"abstract":"<p><p>Raw attitudes relate to the food cultures, eating habits, and behaviours of people in relation to the consumption of raw, partially cooked, and fermented freshwater fish dishes, which puts people at risk of Ophistochis viverrini and other parasitic infections. The chapter reviews raw attitudes within the countries and across the borders of the greater Mekong region, particularly northeast Thailand, Lao PDR, Vietnam, and Cambodia. Rather than treat each nation-state as an isolated epidemiological box, the chapter explores transborder complexity in relation to multiple anthropogenic transformations to the landscapes of the region and developmental impacts upon ecosystems and life cycles. Economic projects such as multiple hydropower dams, irrigation schemes, water-diversions, roads, and aquaculture ponds have significant impacts on FTZ life-cycle dynamics. In addition, many ecological changes are transboundary ones, and there are added complications relating human mobility, altered agrarian landscapes, and significant numbers of migrant workers. The chapter also examines public health programmes and educational interventions which are altering perceptions of O. viverrini and cholangiocarcinoma over time. A key argument is the need for transdisciplinary scientific and social science strategies alongside multi-pronged health interventions, such as 'the CASCAP model'. There exist many unknowns and gaps relating to widespread anthropogenic modifications upon life cycles, upon lifestyles, livelihoods, and human behaviours, which require research projects that span socio-economic, ecological, geographical, and public health dynamics of disease.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"281-347"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10142319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Imaging Techniques. 新成像技术。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_6
Nittaya Chamadol, Richard Syms, Vallop Laopaiboon, Julaluck Promsorn, Kulyada Eurboonyanun
{"title":"New Imaging Techniques.","authors":"Nittaya Chamadol,&nbsp;Richard Syms,&nbsp;Vallop Laopaiboon,&nbsp;Julaluck Promsorn,&nbsp;Kulyada Eurboonyanun","doi":"10.1007/978-3-031-35166-2_6","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_6","url":null,"abstract":"<p><p>The chapter discusses the advancement of new imaging techniques, the role of imaging in CCA diagnosis, anatomical and morphological classification, ultrasound screening of CCA, ultrasound findings of MF-CCA, PI-CCA, ID-CCA, the use of CT in CCA diagnosis, staging and treatment planning, CT volumetry and estimation of future liver remnant, post-treatment follow-up and surveillance, MRI imaging, Positron Emission Tomography (PET)/CT, limitations to contrast studies and resolution, internal receivers for CCA imaging, and in vitro imaging of CCA.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"109-145"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opisthorchis viverrini Life Cycle, Distribution, Systematics, and Population Genetics. viverrini阿片类动物的生命周期、分布、系统学和群体遗传学。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_2
Weerachai Saijuntha, Ross H Andrews, Paiboon Sithithaworn, Trevor N Petney
{"title":"Opisthorchis viverrini Life Cycle, Distribution, Systematics, and Population Genetics.","authors":"Weerachai Saijuntha, Ross H Andrews, Paiboon Sithithaworn, Trevor N Petney","doi":"10.1007/978-3-031-35166-2_2","DOIUrl":"10.1007/978-3-031-35166-2_2","url":null,"abstract":"<p><p>Opisthorchis viverrini plays a key role as the carcinogenic liver fluke causing bile duct cancer in Southeast Asia. A comprehensive understanding of its life cycle, distribution, systematics, and population genetics is critically important as they underpin the effective development and establishment of future prevention and control programs that center on opisthorchiasis and cholangiocarcinoma. This chapter provides detailed information concerning the basic biology and updated information of O. viverrini related to its host life cycle, transmission route via raw, partially cooked or fermented freshwater cyprinid fish, endemic areas, and the discovery of new foci. Previous sequential studies over the last two decades on the phylogenetic and systematic relationships, genetic variation, and population genetics of O. viverrini as well as its snail intermediate host Bithynia spp. are presented and discussed, which have led to the currently known complex species level systematics and population genetics framework of this host-parasite system. Additionally, further directions for comprehensive research are suggested to provide a more complete understanding of liver fluke, O. viverrini-related cholangiocarcinoma.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"7-25"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery. 手术。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_7
Narong Khuntikeo, Ake Pugkhem, Tharatip Srisuk, Vor Luvira, Attapol Titapun, Theerawee Tipwaratorn, Vasin Thanasukarn, Vivian Klungboonkrong, Jitraporn Wongwiwatchai
{"title":"Surgery.","authors":"Narong Khuntikeo,&nbsp;Ake Pugkhem,&nbsp;Tharatip Srisuk,&nbsp;Vor Luvira,&nbsp;Attapol Titapun,&nbsp;Theerawee Tipwaratorn,&nbsp;Vasin Thanasukarn,&nbsp;Vivian Klungboonkrong,&nbsp;Jitraporn Wongwiwatchai","doi":"10.1007/978-3-031-35166-2_7","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_7","url":null,"abstract":"<p><p>This chapter provides a comprehensive background from basic to applied knowledge of surgical anatomy which is necessary for the surgical treatment of cholangiocarcinoma (CCA) patients. Significant advances that have been made in the surgical treatment of CCA were examined. For instance, in-depth details are provided for appropriate preoperative assessment and treatment to optimize patient status and to improve the outcome of surgical treatment(s). Comprehensive details are provided for the surgical techniques and outcomes of treatments for each type of CCA with clear illustrations and images. This chapter also describes the role of minimally invasive surgery and liver transplantation in CCA treatment.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"147-222"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10142318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community Awareness and Education: In the West and Southeast Asia. 社区意识和教育:在西方和东南亚。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_12
Helen Morement, Narong Khuntikeo
{"title":"Community Awareness and Education: In the West and Southeast Asia.","authors":"Helen Morement,&nbsp;Narong Khuntikeo","doi":"10.1007/978-3-031-35166-2_12","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_12","url":null,"abstract":"<p><p>Although cholangiocarcinoma (CCA) or bile duct cancer is considered rare, worldwide it is the second most common primary liver cancer. The incidence is increasing globally, and mortality is high owing to its aggressiveness, late diagnosis, and refractory nature. In this chapter, the awareness of cholangiocarcinoma in the West and in Southeast Asia, particularly Thailand, is explored. The background to this cancer in each region is described, and the challenges faced by both by healthcare professionals and patients are uncovered. Although there is a growing number of organisations working at every level in each region to improve the situation for those with cholangiocarcinoma, there remains little awareness of the public health importance of this cancer. However, it is with health agencies and those at government level that hopes for an improved future for all those with cholangiocarcinoma must lie.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"349-359"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Hallmarks of Liver Fluke Related Cholangiocarcinoma: Insight into Drug Target Possibility. 肝吸虫相关胆管癌的特征:对药物靶点可能性的洞察。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_4
Watcharin Loilome, Nisana Namwat, Apinya Jusakul, Anchalee Techasen, Poramate Klanrit, Jutarop Phetcharaburanin, Arporn Wangwiwatsin
{"title":"The Hallmarks of Liver Fluke Related Cholangiocarcinoma: Insight into Drug Target Possibility.","authors":"Watcharin Loilome,&nbsp;Nisana Namwat,&nbsp;Apinya Jusakul,&nbsp;Anchalee Techasen,&nbsp;Poramate Klanrit,&nbsp;Jutarop Phetcharaburanin,&nbsp;Arporn Wangwiwatsin","doi":"10.1007/978-3-031-35166-2_4","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_4","url":null,"abstract":"<p><p>Cholangiocarcinoma (CCA) is a malignant tumor of the biliary tree that is classified into three groups based on its anatomic location: intrahepatic (iCCA), perihilar (pCCA), and distal (dCCA). Perihilar CCA is the most common type and accounts for 50-60% of CCA cases. It is followed by distal CCA and then intrahepatic CCA that account for 20-30% and 10-20% of cases, respectively. This chapter discusses the hallmarks of liver fluke related CCA and explores insights into drug target possibilities.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"53-90"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10154157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introduction. 介绍。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_1
Narong Khuntikeo, Ross H Andrews, Trevor N Petney, Shahid A Khan
{"title":"Introduction.","authors":"Narong Khuntikeo,&nbsp;Ross H Andrews,&nbsp;Trevor N Petney,&nbsp;Shahid A Khan","doi":"10.1007/978-3-031-35166-2_1","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_1","url":null,"abstract":"<p><p>Cholangiocarcinoma (CCA) is a lethal cancer arising in the bile ducts within and just outside the liver. It occurs worldwide and falls into two etiologically defined groups, one related to chronic liver fluke infection and the other not. Liver fluke-related CCA is found in continental Southeast Asia (caused by Opisthorchis viverrini with infection leading to opisthorchiasis), East Asia (Clonorchis sinensis), and Eastern Europe and Russia (Opisthorchis felineus). Both O. viverrini and C. sinensis are classified as group one carcinogens, while recent data from O. felineus suggest the same. In Southeast Asia, an estimated 67.3 million people are at risk of O. viverrini infection and subsequently developing CCA. When the three liver fluke species are considered, an estimated 700 million people are at risk of infection and developing CCA globally. The northeast of Thailand (Isan) is the world's hot spot of liver fluke infection and CCA. Early detection, diagnosis, and surgical intervention/curative treatment of CCA are critical to increase life expectancy and quality of life of people in the region and globally. Despite concentrated recent efforts focusing on a multidisciplinary approach to understand the ecology, epidemiology, biology, public health, and social significance of infection by cancer causing liver flukes, it remains an underestimated and under-resourced public health problem. In addition, it is still believed to be a regional problem without global significance-this is not the case. This book focuses on O. viverrini as the main causative agent of CCA in Southeast Asia, but many aspects detailed in the following chapters also relate to the two other liver fluke species. Our aim is to produce a holistic framework including the basic biology of O. viverrini and its relation to the epidemiology of the disease through diagnosis to treatment, including palliative methods, pathology, and control.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathology of Cholangiocarcinoma. 胆管癌的病理。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_5
Supinda Koonmee, Prakasit Sa-Ngiamwibool, Chaiwat Aphivatanasiri, Waritta Kunprom, Piyapharom Intarawichian, Walailak Bamrungkit, Sakkarn Sangkhamanon, Malinee Thanee
{"title":"Pathology of Cholangiocarcinoma.","authors":"Supinda Koonmee,&nbsp;Prakasit Sa-Ngiamwibool,&nbsp;Chaiwat Aphivatanasiri,&nbsp;Waritta Kunprom,&nbsp;Piyapharom Intarawichian,&nbsp;Walailak Bamrungkit,&nbsp;Sakkarn Sangkhamanon,&nbsp;Malinee Thanee","doi":"10.1007/978-3-031-35166-2_5","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_5","url":null,"abstract":"<p><p>The liver excretes bile through the biliary system, which has a complicated anatomical structure. Cholangiocarcinoma, a malignant bile duct epithelial tumor, is separated into intrahepatic and extrahepatic portions depending on the structure of the bile duct and exhibits both similarities and varieties in patient presentations and staging. The three main macroscopic characteristics of cholangiocarcinoma-mass formating, intraductal growth, and periductal infiltrating types-allow pathologists and surgeons to see and analyze the cancerous tissue. The majority of cholangiocarcinoma patients are in advanced stages and poor prognosis. Although surgery is the main treatment option, target therapy based on molecular pathology background offers hope for improving patient's prognosis.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"91-107"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Innovations (Isan Cohort). 数字创新(Isan Cohort)。
Recent Results in Cancer Research Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-35166-2_10
Bandit Thinkhamrop, Kavin Thinkhamrop, Chaiwat Tawarungrueng, Panuwat Prathumkham
{"title":"Digital Innovations (Isan Cohort).","authors":"Bandit Thinkhamrop,&nbsp;Kavin Thinkhamrop,&nbsp;Chaiwat Tawarungrueng,&nbsp;Panuwat Prathumkham","doi":"10.1007/978-3-031-35166-2_10","DOIUrl":"https://doi.org/10.1007/978-3-031-35166-2_10","url":null,"abstract":"<p><p>Innovations in digital procedures are discussed and highlighted in this chapter providing a comprehensive background and an overview of the Cholangiocarcinoma Screening and Care Program (CASCAP), and the innovative data base known as the Isan cohort, including the O. viverrini - CCA module, tele-radiology, databases for pathology, surgery, palliative care, and a randomized controlled trial database.</p>","PeriodicalId":39880,"journal":{"name":"Recent Results in Cancer Research","volume":"219 ","pages":"269-280"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书