{"title":"Prevalence of glaucoma in first-degree relatives of patients with primary open-angle glaucoma and normal-tension glaucoma","authors":"Preeti Gupta, H. Pai","doi":"10.35119/asjoo.v16i2.374","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.374","url":null,"abstract":"Objective: To determine the prevalence of glaucoma in first-degree relatives of patients with primary open-angle glaucoma (POAG) and normal tension glaucoma (NTG). \u0000Methods: Observational study of first-degree relatives of patients with POAG and NTG who were screened for glaucoma. \u0000Results: A total of 66 first-degree relatives of patients with glaucoma (POAG/NTG) were included in the study. We found a prevalence rate of 16.6%: 13.6% were diagnosed to have the disease and 3% were newly detected to have glaucoma during the study. We found that although 66.7% of the subjects were aware of the family history of glaucoma, only 36.4% were aware that they were at increased risk of developing glaucoma. \u0000Conclusion: In our study, we found high prevalence of glaucoma in first-degree relatives of patients with glaucoma. This highlights the importance of selective screening of high-risk groups such as first-degree relatives of patients with POAG/NTG.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41313378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of anterior chamber depth on postoperative refractive outcome in Chinese eyes","authors":"Rachel Shet Hui Wong, K. Ong","doi":"10.35119/asjoo.v16i2.366","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.366","url":null,"abstract":"Aim or Purpose: This study aims to evaluate the refractive surprise (RS) after cataract surgery with various intraocular lens (IOL) formulas in eyes with very shallow or deep anterior chamber depth (ACD). \u0000Design: This is a prospective cohort study of patients from a private ophthalmology practice in Sydney. \u0000Methods: Thirty-one patients who had their cataract surgery in 2014 were included. The cohort consists of 20 eyes with ACD < 2.8 mm and 25 eyes with ACD > 3.2 mm. Patients’ demographic variables and their predicted refractive outcomes using the SRK-T, Haigis, Holladay 1, and Holladay 2 IOL formulas were collected. Actual refractive outcomes were obtained from consultations at least one-month postoperatively. RS was calculated from the difference between predicted refraction outcome of IOL formulas and the actual postoperative refraction achieved. \u0000Results: The linear correlations between ACD and RS were not significant (p > 0.05). In the group with ACD < 2.8 mm, the mean refractive surprise using SRK-T, Haigis, Holladay 1, and Holladay 2 formulas were -0.191 ± 0.541, -0.189 ± 0.444, -0.201 ± 0.449, and -0.154 ± 0.489 D, respectively. In the group with ACD > 3.2 mm, the mean refractive surprise using the IOL formulas were -1.364 ± 0.541, -1.420 ± 0.541, 0.027 ± 0.394, and -0.045 ± 0.343 D, respectively. \u0000Conclusion: The positive linear correlation between ACD and RS was weak. In eyes with ACD < 2.8 mm, the least RS was found with the Holladay 2 formula, while in eyes with ACD > 3.2 mm, this was found with Holladay 1.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43471262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bloody tears: a case of bilateral ulcerative blepharitis","authors":"Praveena K. Gupta, Laura Di Meglio, A. Behrens","doi":"10.35119/asjoo.v16i2.376","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.376","url":null,"abstract":"Chronic blepharitis leading to bilateral ulceration is rare to encounter. A 49-year-old African American female presents with bloody tears, severe pain, and photophobia in both eyes. Clinical presentation called for ulceration on the upper lid margins with excavated wound which bled on gentle rubbing. A systemic health review in combination of the symptoms and clinical picture led to the diagnosis of severe ulcerative blepharitis. Immediate oral antibiotics were started along with topical antibiotic cream. Ulcerative blepharitis can be easily misdiagnosed with sebaceous cell carcinoma. The pathophysiology of ulcerative blepharitis points to synergy between infectious entity and inflammatory aetiology, with either bacterial or fungal microorganisms as the trigger agents. Almost all cases of ulcerative blepharitis should include a dermatological evaluation given there is a strong association between ulcerative blepharitis and atopic dermatitis.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69888172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Tomy, R. Maheshwari, A. Muhammed, V. Kalikivayi, Sajeev Cherian Jacob
{"title":"Safety and efficacy of posterior iris claw intraocular lens fixation in aphakic patients","authors":"R. Tomy, R. Maheshwari, A. Muhammed, V. Kalikivayi, Sajeev Cherian Jacob","doi":"10.35119/asjoo.v16i2.368","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.368","url":null,"abstract":"Purpose: To assess the indications and visual outcome of eyes undergoing posterior iris fixated intraocular lens (IFIOL) implantation for aphakia, to identify reasons for poor visual outcome, and report occurrence of complications. \u0000Methods: In this retrospective case series study, all cases of posterior IFIOL fixation performed over a 30-month period were identified retrospectively. Preoperative and postoperative evaluations comprised objective and subjective refraction, best corrected visual acuity (BCVA), slit lamp biomicroscopy, applanation tonometry, and dilated fundus examination. \u0000Results: Fifty-six eyes of 56 patients were analyzed. Mean age was 60.55 ± 17.2 years. The most common indication for IFIOL implantation was surgical aphakia following complicated cataract surgery (n = 33; 58.9%) followed by trauma (n = 10; 17.9%), dropped nucleus/IOL during primary surgery (n = 6; 10.7%), and subluxated/dislocated lens-induced glaucomas (n = 5; 8.9%). BCVA better than or equal to their preoperative BCVA was achieved in 96.43% patients. The surgical aphakia and paediatric/adolescent groups had the best visual results while the dropped nucleus/IOL group and subluxated lens-induced glaucoma groups fared poorly. On the long-term follow-up visit, the most common complication noted was pigment dusting on the corneal endothelium (65.7%). \u0000Conclusion: The long-term results suggest that posterior IFIOL implantation is a safe and effective method for correction of aphakia and can be used for a wide range of indications in eyes without adequate capsule support. It may be considered an easier and faster alternative with minimal manipulation to anterior segment structures in paediatric and post-traumatic aphakic eyes.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45675409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Glaucoma and frequent flying","authors":"K. Ong, L. Ong, L. Armellin","doi":"10.35119/asjoo.v16i2.562","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.562","url":null,"abstract":"To evaluate the possible impact of frequent flying on glaucoma progression.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46086774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of variation in predicted refraction between different intraocular lens formulae","authors":"K. Ong, Liaoyun Feng","doi":"10.35119/asjoo.v16i2.389","DOIUrl":"https://doi.org/10.35119/asjoo.v16i2.389","url":null,"abstract":"Variations of 0.5 D in predicted refraction between the different intraocular lens (IOL) calculation formulae may occur in 19.4% cases. This has implications when reporting refractive surprise. It also shows that it is beneficial to consider more than one IOL formula when choosing IOL power for cataract surgery. \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41457959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in corneal properties and its effect on intraocular pressure measurement following phacoemulsification with intraocular lens implantation with or without trabeculectomy","authors":"Ashim Dey, R. David, R. Asokan, R. George","doi":"10.35119/asjoo.v16i1.344","DOIUrl":"https://doi.org/10.35119/asjoo.v16i1.344","url":null,"abstract":"Purpose: To evaluate the changes incorneal biomechanical properties and their effect on pre and postoperative differences in IOP measurement by each tonometer \u0000Design: Observational study. \u0000Methods: The study was done in subjects who underwent phacoemulsification with intraocular lens (IOL) implantation (phaco-IOL) and combined phacoemulsification with IOL implantation and trabeculectomy (phaco-trab). IOP was measured by a single trained examiner using rebound tonometer (RBT), Ocular Response Analyzer (ORA), Goldmann applanation tonometer (GAT), dynamic contour tonometer (DCT), and Tono-Pen. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured using ORA, central corneal thickness (CCT) using ultrasonic pachymeter, and corneal curvature (CR) with manual keratometry. All measurements were done one week prior to surgery and after four weeks and six weeks of the two surgeries, respectively. Only the operated eye was included for analysis. \u0000Results: Twenty-nine eyes of 29 normal subjects who underwent phaco-IOL and 23 eyes of 23 glaucoma subjects who underwent phaco-trab were studied. Increase in CCT [10.2 ± 14.86 microns, p = 0.001], decrease in CH [0.82 ± 1.38 mmHg, p = 0.003] and CRF [0.97 ± 1.0 mmHg, p < 0.001] were found post-phaco-IOL, whereas post-phaco-trab decrease in CCT [16.61 ± 15.22 microns, p < 0.001], CRF [2.28 ± 1.93 mmHg, p < 0.001] with increase in CH [0.95 ± 1.89 mmHg, p = 0.03] were noted. Multiple linear regression analysis showed significant associations for change in CH and CRF with change in IOP and not with CCT and CR postoperatively. \u0000Conclusion: Alterations in CH and CRF were associated with changes in IOP measured postoperatively by different tonometers. CH and CRF changes contribute to postoperative changes in measured IOP. \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44407928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cataract surgery under topical anaesthesia - white or yellow light","authors":"K. Ong, Andrew Yue, S. Beka","doi":"10.35119/asjoo.v16i1.345","DOIUrl":"https://doi.org/10.35119/asjoo.v16i1.345","url":null,"abstract":"To evaluate whether there is a difference in comfort level between yellow light and white light for the patient having cataract surgery under topical anaesthesia. \u0000 \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46534120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral simultaneous acute angle closure in an adult Nepalese woman","authors":"Sabin Sahu, L. Puri","doi":"10.35119/ASJOO.V16I1.348","DOIUrl":"https://doi.org/10.35119/ASJOO.V16I1.348","url":null,"abstract":"Purpose: To report a case of bilateral simultaneous angle closure in an adult Nepalese woman without any known secondary cause. \u0000Methods: Observational case report. \u0000Results: A 50-year-old Nepalese woman presented with decreased vision, pain, redness, and watering in both eyes with associated coloured haloes, nausea, and vomiting for 10 days. At presentation, her visual acuity was 20/400 in the right eye and hand motions close to face with accurate projection of rays in the left eye. Intraocular pressure was 38 mmHg in the right eye and 48 mmHg in the left eye without any antiglaucoma medications. A slit-lamp examination revealed bilateral circum-corneal conjunctival congestion, corneal edema, and shallow anterior chambers. Both pupils were mid-dilated and non-reactive to light. Gonioscopy showed closed angles in all four quadrants bilaterally. Posterior segment examination revealed normal optic disc with cup-disc-ratio of 0.3 in the right eye, and blurring of disc margin with cup-disc-ratio of 0.3 in the left eye. The patient was started on systemic acetazolamide 250 mg 4 times a day, topical brimonidine 0.2% and timolol 0.5% 2 times a day, and topical dexamethasone 6 times a day in both eyes, following which IOP reduced to 11 and 12 mmHg, respectively, the corneal edema subsided, but the anterior chamber remained shallow. Laser peripheral iridotomy was performed in the right eye and surgical peripheral iridectomy was performed in the left eye. After two weeks, vision improved to 20/30 in both eyes with normal intraocular pressure off antiglaucoma medications. Anterior chambers deepened significantly with clear corneas bilaterally. Gonioscopy at this stage showed essentially open angles with appositional closure in superior and temporal quadrants in the right eye and open angles in all four quadrants in the left eye. Posterior segment evaluation revealed normal optic disc in both eyes. \u0000Conclusions: Bilateral simultaneous acute angle closure is a rare presentation with very few reported secondary causes. We report a case of bilateral simultaneous angle closure in an adult Nepalese woman without any known secondary cause. The case was successfully managed with laser peripheral iridotomy in the right eye and surgical peripheral iridectomy in the left eye. \u0000 ","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42241332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin Egnasious, Krithica Srinivasan, Ramesh S. Ve, Babu Noushad
{"title":"Knowledge, awareness, perception, and willingness towards eye donation among the literate working population","authors":"Justin Egnasious, Krithica Srinivasan, Ramesh S. Ve, Babu Noushad","doi":"10.35119/asjoo.v16i1.336","DOIUrl":"https://doi.org/10.35119/asjoo.v16i1.336","url":null,"abstract":"Aim: To evaluate awareness, knowledge, and perception towards eye donation among the literate working population. \u0000Methodology: A new questionnaire on eye donation was developed from existing literature and face validation was performed among subject experts. Repeatability of the questionnaire was performed among 30 subjects. A total of 23 questions were there, out of those 6 questions for evaluating awareness, 13 questions for evaluating knowledge, and 4 questions for dertermining the subjects' perception. The questionnaire was distributed among subjects working in both the health science and non-health science fields. From their responses, knowledge, awareness, and perception towards eye donation in working literate population were assessed. A pledge form was also given along with the questionnaire to find the subjects' actual willingness. \u0000Results: Repeatability: The questions in the awareness and knowledge domain showed good repeatability (p > 0.05). More than 50 % of the parameters in the perception domain showed poor repeatability (p < 0.05). Out of 189 subjects assessed, there were 97 health science and 92 non-health science subjects with total mean age 30 ± 7 years. Good awareness was present between health science (96%) and non-health science (94%). Only 21% of the health science and 11% of the non-health science group had good knowledge about eye donation. Only 25% said ‘yes’ to willingness about eye donation. However, only 3% filled the pledge form. No-one from the non-health science population filled the pledge form. Health science professionals showed more willingness to donate eyes compared to the non-health science group after adjusting for qualification, age ,and gender (odds ratio 2.158, p = 0.031, 95% CI (1.073, 4.341)). Study participants shared willingness to donate eyes and responded against negative perceptions such as \"Family members object to eye donation” (odds: 3.75, p = 0.030, 95% CI (1.14, 12.39)), “Dislike of separating eye from the body” (odds:7.02, p =0.006, 95% CI (1.73, 28.42)), and “Donating an organ is against my religious belief” (odds: 8.51,p = 0.039, 95% CI (1.11, 65.09)). \u0000Conclusion: Our study showed that education qualification and the perception like ‘eye donation is against religious beliefs’ and ‘dislike to separate eye from the body’ showed significant effect on the willingness to donate eyes. More than awareness and knowledge, perception about eye donation had more impact on the willingness to donate eyes. Therefore, more campaigns emphasizing the importance of eye donation need to be conducted to change the perceptions about eye donation rather than improving awareness or knowledge.","PeriodicalId":39864,"journal":{"name":"Asian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49426583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}