Drug Discovery Today: Disease Models最新文献_第9页

Modeling approaches for hepatic spatial heterogeneity in pharmacokinetic simulations 药物动力学模拟中肝脏空间异质性的建模方法

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.09.002

Lars Ole Schwen , Lars Kuepfer , Tobias Preusser

引用次数: 5

Assessing interindividual variability by Bayesian-PBPK modeling 通过贝叶斯- pbpk模型评估个体间变异性

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.08.001

Markus Krauss, Andreas Schuppert

引用次数: 3

Reverse engineering the inflammatory “clock”: from computational modeling to rational resetting 对炎症“时钟”进行逆向工程:从计算建模到理性重置

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.03.001

Yoram Vodovotz

引用次数: 2

Computational modelling of Hedgehog signalling in liver regeneration 肝脏再生中Hedgehog信号传导的计算模型

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.06.001

Madlen Matz-Soja

引用次数: 3

Editorial to “Computational models of liver disease 2016” 《肝脏疾病计算模型2016》社论

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.11.002

Adriano M. Henney

引用次数: 1

Systems pharmacology of hepatic metabolism in zebrafish larvae 斑马鱼幼体肝脏代谢的系统药理学研究

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.04.003

Rob C. van Wijk , Elke H.J. Krekels , Thomas Hankemeier , Herman P. Spaink , Piet H. van der Graaf

引用次数: 32

Towards knowledge-driven cross-species extrapolation 向着知识驱动的跨物种外推

Drug Discovery Today: Disease Models Pub Date : 2016-12-01 DOI: 10.1016/j.ddmod.2017.02.008

Christoph Thiel , Ute Hofmann , Ahmed Ghallab , Rolf Gebhardt , Jan G. Hengstler , Lars Kuepfer

引用次数: 6

The pharmacological audit trail (PhAT): Use of tumor models to address critical issues in the preclinical development of targeted anticancer drugs 药理学审计追踪(PhAT):使用肿瘤模型来解决靶向抗癌药物临床前开发中的关键问题

Drug Discovery Today: Disease Models Pub Date : 2016-09-01 DOI: 10.1016/j.ddmod.2017.07.002

Olivia Rossanese , Suzanne Eccles , Caroline Springer , Amanda Swain , Florence I. Raynaud , Paul Workman , Vladimir Kirkin

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引用次数: 8

Preclinical models of childhood cancer for the development of targeted therapies 儿童癌症的临床前模型用于靶向治疗的发展

Drug Discovery Today: Disease Models Pub Date : 2016-09-01 DOI: 10.1016/j.ddmod.2017.02.001

Raushan T. Kurmasheva, Peter J. Houghton

引用次数: 0

Editorial DDT: Cancer models in drug development DDT:药物开发中的癌症模型

Drug Discovery Today: Disease Models Pub Date : 2016-09-01 DOI: 10.1016/j.ddmod.2017.10.001

Robert M. Mader

引用次数: 0