Global Academic Journal of Medical Sciences最新文献

{"title":"Assessment of Microalbuminuria and Hs-CRP for Early Detection of Diabetic Nephropathy in Type 2 Diabetes","authors":"Dr. Mahmud Javed Hasan, Dr. Nitai Chandra Ray, Dr. Muhammad Abdul Bari, Prof. Dr. Md. Aminul Islam, Dr. Sultan Ahmed","doi":"10.36348/gajms.2024.v06i04.001","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i04.001","url":null,"abstract":"Background: Diabetic nephropathy is one of the most prevalent complications of type 2 diabetes and is associated with an increased risk of end-stage renal disease in patients whose disease is not diagnosed in time. Formerly, microalbuminuria was used as the first marker, but recently, high-sensitivity c-reactive protein (hs-CRP) may be useful for early diagnosis. Aims and Objectives: This study aimed to compare microalbuminuria and hs-CRP in type 2 diabetic patients and test their efficiency in diagnosing early diabetic nephropathy. Methods: This is a cross-sectional observational study with 75 patients with type 2 DM. Demographic variables, microalbuminuria, and hs-CRP were measured and recorded. Microalbuminuria and positive or negative CRP were used to stratify patients into groups of MG, LG, and control. The t-test was used to test for differences in hs-CRP levels between the groups. Results: As for renal markers, microalbuminuria was elevated at 60% among these patients. The hs-CRP levels were higher in patients with microalbuminuria compared to patients without it (3. 1 ± 1. 2 mg/L versus 1. 5 ± 0. 8 mg/L, respectively; p = 0.001). Patients with microalbuminuria were older, their diabetes duration was longer, HDL was lower, and triglyceride levels were higher in comparison to patients without microalbuminuria. These observations were consistent with the CRP-positive group compared with the CRP-negative group. Conclusions: The research suggested a relationship between increased hs-CRP concentrations and microalbuminuria among patients with type 2 diabetes. This indicates that hs-CRP could be a potential biomarker for detecting diabetic renal disease early enough. Therefore, screening for hs-CRP in combination with screening for microalbuminuria could increase the early detection of kidney complications in type 2 diabetes. More large-cohort longitudinal follow-up studies are warranted to determine the diagnostic value of hs-CRP for predicting the development of diabetic nephropathy and to define optimal cut-off levels.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"45 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Early Age Colorectal Cancer among Patients Attending at National Institute of Cancer Research & Hospital","authors":"Mohammad Habibur Rahaman, Muhammad Rafiqul Islam, Narina Khatun, Parveen Shahida Akhtar, Md. Rashedul Islam, Md. Abul Ahsan, Sumana Das, Salman Bashar Al Ayub","doi":"10.36348/gajms.2024.v06i02.003","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i02.003","url":null,"abstract":"Background: Colorectal cancer (CRC) poses a significant public health burden worldwide, with a notable trend of increasing incidence among individuals aged 20 to 50 years. Understanding the risk factors associated with early-onset CRC is crucial for developing targeted prevention and intervention strategies, particularly in limited-resource settings. Objective: This study aimed to identify and analyze the risk factors contributing to the development of early-onset CRC in a population from a limited-resource country. Method: A comparative study was conducted among 178 CRC patients admitted to the National Institute of Cancer Research & Hospital (NICRH), Dhaka. Patients were divided into two groups: Group-A (age 20-50 years) and Group-B (age >50 years). Demographic and clinical data were collected, and statistical analyses were performed to determine associations between various risk factors and early-onset CRC. Results: The mean age of Group-A subjects was 43.6±7.1 years, significantly younger than Group-B subjects (59.2±9.3 years). Male patients constituted 69.1% of the cohort, with a statistically significant male-to-female ratio of 2.2:1. Higher BMI (≥25) was strongly associated with early-onset CRC (p<0.01). Occupations such as business and middle socioeconomic status were significantly linked to early-onset CRC. Regular exercise (>30 minutes daily) demonstrated a protective effect against CRC development. Consumption of red meat and fast food was associated with a higher risk of CRC, while regular consumption of vegetables was protective. Familial adenomatous polyposis (FAP) presence was significantly associated with early-onset CRC. Conclusions: Male sex, high BMI, specific occupations, dietary factors, and presence of FAP emerged as key risk factors for early-onset CRC. Encouraging regular exercise and promoting healthy dietary habits, particularly reducing red meat and fast-food intake, are crucial in mitigating the risk of early-onset CRC in similar populations.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"106 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140380601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Retinal Necrosis Complicated by Serous Retinal Detachment Associated with Varicella-Zoster Virus Infection in an Immunocompetent Young Adult","authors":"D. Batungwanayo, A. Najah, S. Nidal, B. Salaheddin, K. Majid, S. belghmaidi, I. Hajji, A. Moutaouakil","doi":"10.36348/gajms.2024.v06i02.002","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i02.002","url":null,"abstract":"Acute retinal necrosis syndrome (ARN syndrome) is a rare, rapidly progressive viral retinitis with a grim functional prognosis. We present a case of a 43-year-old immunocompetent woman who experienced unilateral acute retinal necrosis, with Varicella-Zoster Virus (VZV) infection as the etiology. A unilateral vesicular facial rash accompanied by rapidly declining visual acuity over 7 days prompted consultation. Intravenous antiviral treatment and panretinal photocoagulation laser (PPR) were initiated, followed by antiviral prophylaxis. The patient developed ophthalmic zona lesions, peripheral retinal ischemia, and unilateral macular serous retinal detachment (SRD). Treatment included valacyclovir, corticotherapy and PPR laser. Knowledge of this condition, diagnosed clinically, is crucial due to its rapid progression and severe complications. Early intervention appears to be a significant prognostic factor, emphasizing its therapeutic urgency.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":" 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140385594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status of Machine Learning and Artificial Intelligence in Cervical Cancer Screening and Diagnosis: A Systematic Review","authors":"Rushin Patel, Mrunal Patel, Zalak Patel, Darshil Patel","doi":"10.36348/gajms.2024.v06i01.008","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i01.008","url":null,"abstract":"Background: Cervical cancer poses a substantial global health challenge, predominantly affecting underprivileged countries. The limitations of current screening methods, such as cytology and visual examination, underscore the need for improved techniques. Artificial intelligence (AI) and machine learning (ML), particularly convolutional neural networks, offer promising solutions in this regard. Methodology: Fifteen studies meeting the inclusion criteria were examined. The PRISMA criteria guided the exploration of cervical cancer screening studies employing AI, ML, and deep learning on PubMed/MEDLINE and Google Scholar. The search focused on \"artificial intelligence\" and \"Pap smear.\" The investigation specifically delves into English-language studies post-2019 that pertain to the machine learning and deep learning classification of cervical cancer using mobile devices. Histology, animal research, and pre-2019 investigations are excluded. Titles and abstracts were carefully reviewed for any discrepancies and subsequently discussed. The process of data extraction involved compiling information from the selected articles. Result: The systematic review investigates the impact of AI and ML on cervical cancer detection, screening, and diagnosis. Our review reveals enhanced accuracy and efficiency in innovative technologies such as CytoBrain and computer-aided diagnostic systems employing Compact VGG and ResNet101. ML techniques like logistic regression, MLP, SVM, KNN, and naive Bayes prove beneficial for managing complex datasets, particularly when combined with class-balancing procedures. The promising aspects include the application of deep learning for automation and AI-assisted digital microscopy. These findings signify a transformative shift in cervical cancer screening, underscoring the potential of ML and AI technologies to elevate diagnostic accuracy and accessibility. Conclusion: Our study demonstrates advancements in both accuracy and responsiveness. Despite recognizing scientific and ethical considerations, the study underscores the potential of AI to enhance cervical cancer care. This systematic review advocates for policymakers and healthcare practitioners to use ongoing research for informed decision-making in this rapidly evolving field.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"203 S614","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140428287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socio-Demographic and Clinical Characteristics of Patients Attending Department of Palliative Medicine in Tertiary Care Hospital","authors":"Sabikun Naher Urmy, A.K.M. Motiur Rahman Bhuiyan, Md. Shaidur Rahman, K. S. Haque, Fahmida Sultana, S. N. Sharmin, M. N. Aktar, Rakiba Sultana, Tasnim Bi","doi":"10.36348/gajms.2024.v06i01.006","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i01.006","url":null,"abstract":"Background: Palliative care focuses on improving quality of life for patients with life-limiting illnesses and their families by addressing physical, psychological, emotional, and spiritual needs. Understanding the specific characteristics of these patients accessing this care is crucial for optimizing services and resource allocation. Therefore, studies focusing on the socio-demographic and clinical characteristics of patients attending palliative medicine departments in tertiary care hospitals are vital. These studies shed light on who accesses palliative care, what diseases they have, and the challenges they face. Method: Individuals aged 18 years and above, diagnosed with cancer, were enlisted in our study, and their sociodemographic-clinical information was gathered. A reassessment was conducted after 3 months, during which their treatments and side-effects profile were examined. Result: The predominant cases in our patient population involved oral cavity cancers, primarily affecting married men aged 40–60 residing in the National Capital Region. Those diagnosed with breast cancer were more inclined to undergo chemotherapy, experiencing associated side effects such as nausea, anorexia, and weight loss. Conclusion: Healthcare providers must be cognizant of these complications and should integrate an effective counseling mechanism before initiating treatment in such patients. Palliative care physicians play a pivotal role in palliative management, serving as trusted figures in their communities and offering both professional and psychotherapeutic support.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"106 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140460043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for CAD Among the Patients with Ischemie Heart Disease- A Cross Sectional Study","authors":"Muhammed Akhtaruzzaman, Md. Amir Hossain, Md. Monir Ahamed, Laila Akter Zahan, M.A. Hossain, Arman Ibne Huq, Md. Rezaul Karim","doi":"10.36348/gajms.2024.v06i01.005","DOIUrl":"https://doi.org/10.36348/gajms.2024.v06i01.005","url":null,"abstract":"Introduction: Coronary heart disease (CHD) is an impairment of heart function due to inadequate blood flow to the heart compared to its needs, caused by obstructive changes in the coronary circulation to the heart. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Objective: To analyses the risk factors for coronary artery disease (CAD) for patients with ischemia heart disease. Methods: A cross sectional study was conducted at Department of Cardiology, Bangladesh Medical College Hospital, Dhaka, Bangladesh from January to December 2022. Total 150 with acute coronary syndrome or coronary angiographic or Electrocardiography evidence of ischemic heart disease. Risk factors studied were the conventional risk factors for coronary artery disease- hypertension, diabetes mellitus, dyslipidemia, body mass index (BMI), smoking, and family history of coronary artery disease Data are collected from the patients, old medical records, Clinical Examination and Laboratory results of the patients were analyzed for the study. Results: A total of 100 (66.6%) patients in the study gave a positive family history for CAD. Based on the blood 'pressure monitoring, the patients were classified according to JNC 7 (reviewed) classification for hypertension as normotensive 78 (78.0%), pre-hypertensive 4(4.0%), stage 1 hypertension was found in 18 patients (18.0%). There was no gender difference noted in the occurrence of hypertension. From the study, diabetes or impaired glucose tolerance (79%) and dyslipidemia (71%) are the major risk factor for Coronary artery disease as only a minority of the study population had hypertension or gives a history of cigarette smoking. 57% of the study population had a family history of coronary artery disease. Among the studied population, 55% of females are with increased BMI, whereas only 16% of males with CAD were with BMI above 30. Conclusion: Among diabetes mellitus and dyslipidemia are the major Risk factor for Coronary artery disease. So early detection of diabetes mellitus and dyslipidemia and proper treatment of both, before developing the end organ damage, play a vital role for the prevention of coronary artery disease.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Right Internal Mammary Artery and Great Saphenous Vein as Secondary Conduits in Myocardial Revascularization: Mohamed VI University Hospital Experience","authors":"Nijimbere Macédoine, Mpira Yves Marien, Thiombiano Abdoulaz, Son Moussa, Arafaou Dicko, Zalikatou Abdoulkrim, Zalle Issaka, El Mardouli Mouhcine, Zahira Zouizra, E. Rachid, Boumzebra Drissi","doi":"10.36348/gajms.2023.v05i06.005","DOIUrl":"https://doi.org/10.36348/gajms.2023.v05i06.005","url":null,"abstract":"Background: In myocardial revascularisation procedures, the underutilisation of the right internal mammary artery remains a concern. This study aimed to compare outcomes between using the right internal mammary artery (RIMA) and the great saphenous vein (GSV) as secondary conduits in Coronary Artery Bypass Grafting (CABG), focusing on early and mid-term postoperative results. Methods: A retrospective analysis of 270 patients who underwent CABG between November 2015 and January 2023 at Mohamed VI University Hospital was conducted. Patients were divided into RIMA and GSV groups for comparative analysis. Results: There were no significant differences in the preoperative characteristics of the study population. Patients in the RIMA group had lower cardiopulmonary bypass time and aortic cross-clamping time (110.70±34.08 vs 127.45±31.17: p<0.00 and 77.67±26.31 vs 82.93±23.66: p<0.00, respectively). The use of GSV was associated with more significant bleeding compared to RIMA (570.46±403.66 vs 761.40±647: p<0.00). However, there were no significant differences in the occurrence of deep sternal wound infection (3.24% vs 4.31%: p=0.8945) between the two groups. Regarding early mortality rates, there was no significant difference observed (5.19% vs 2.58%: p=0.4458). Mid-term results showed no difference in the recurrence of angina and dyspnea between the groups. Conclusion: The study indicated that RIMA used as a secondary graft in CABG wasn't linked to sternal wound infection or bleeding, suggesting its superiority as a graft choice. The findings aligned with prior research, advocating for the benefits of employing RIMA in myocardial revascularization.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"153 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139171998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chondrolysis of the Nasal Cartilages as a Sequela of Rhinophyma Treatment: A Case Report and Literature Review","authors":"B. Nshimirimana, A. Jaifi, M. Hattab, D. Ndélafei, Z. Aziz, N. Mansouri-Hattab","doi":"10.36348/gajms.2023.v05i06.004","DOIUrl":"https://doi.org/10.36348/gajms.2023.v05i06.004","url":null,"abstract":"Chondrolysis is a rare pathology that can complicate rhinophyma surgery. The resulting defect poses more complex repair challenges. We report a case of chondrolysis of the nasal cartilages as a sequel to rhinophyma treatment. Our objective was, based on this case and literature data, to present our therapeutic approach. This concerned a 65-year-old patient, presented with a voluminous rhinophyma evolving for 15 years, causing not only aesthetic impairment but also nasal obstruction. The excision was performed in one piece with an electric scalpel, hemostasis achieved using a bipolar coagulating forceps while preserving the nasal cartilages. The excision site was left for directed healing. Postoperative outcomes for our patient were marked by transfixing apexo-alar nasal substance losses following chondrolysis of the nasal cartilages. Faced with this defect, a repair surgery was undertaken not only to fill the substance loss but also to restore an appearance as normal and aesthetic as possible, ensuring functional reconstruction.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"85 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139171522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of COVID-19 on Otitis Media with Effusion in a Tertiary Care Hospital","authors":"Md. Faysol Alam, Anwara Khatun, A. R. Mahbub, Md. Atiqur Rahman, K.M. Shakila Sultana","doi":"10.36348/gajms.2023.v05i06.003","DOIUrl":"https://doi.org/10.36348/gajms.2023.v05i06.003","url":null,"abstract":"Background: Otitis media with effusion (OME), sometimes referred to as secretory or severe otitis media, is among the most common conditions in children. An estimated 80% of all children have had at least 1 episode of OME by the age of 10 years, with a peak of prevalence in the first 2 years of life. Objectives: The aim of the study was to evaluate the effects of COVID-19 on otitis media with effusion in a tertiary care hospital. Methods: This cross-section observational study Rangpur Medical College & Hospital Rangpur, Bangladesh. The duration of the period from July 2021 to July 2022. A total of 80 children, Age <6 months or >12 years with Otomicroscopic evidence of tympanosclerosis, choesteatoma, eardrum perforation, or complete stenosis or atresia of the external auditory canal were included in the study. Severely ill children and not willing to participate were excluded. After collection, the data were checked and cleaned, followed by editing, compiling, coding and categorizing according to the objectives and variable to detect errors and to maintain consistency, relevancy and quality control. Statistical evaluation of the results used to be obtained via the use of a window-based computer software program devised with Statistical Packages for Social Sciences (SPSS- 24). Results: Before pandemic 9.52% of the respondents had <3 years of age, 23.80% were 3-7 years, 57.14% were 7-10 years and 10% had 10-12 years of age. During pandemic 11.42% of the respondents had <3 years of age, 19.04% were 3-7 years, 61.90% were 7-10 years and 7.62% had 10-12 years of age. No significant difference in mean age before and during pandemic. Before pandemic 65% of the respondents were male and 35% were female. During pandemic 40% of the respondents were male and 60% were female. Before pandemic 28.57% respondents were underweight, 57.14% were in normal range and 14.28% were overweight. During pandemic 26.67% were underweight, 55.23% were in normal range and 18% were overweight. The prevalence of OME was 40.6% before pandemic and 2.3% during pandemic. Children with chronic OME had a higher rate of disease resolution during pandemic (95%) than those examined before pandemic (5%, P .001). Conclusion: The findings of our study, in our opinion, have important clinical implications, implying that keeping children at home for as little as 2 months may allow for the resolution of most cases with severe and refractory OME. This method, while possibly advantageous for all age groups, should be given special consideration for young children, who are the most susceptible to otitis.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"354 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138983214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laubry-PEZZI Syndrome Surgical Repair in Adult: A Case Report","authors":"Nijimbere Macédoine, Mpira Marien Yves, Son Moussa, Thiombiano Abdoulaziz, Arafaou Dicko, Zalikatou Abdoulkrim, Boumzebra Drissi","doi":"10.36348/gajms.2023.v05i06.002","DOIUrl":"https://doi.org/10.36348/gajms.2023.v05i06.002","url":null,"abstract":"The presence of aortic regurgitation (AR) in the setting of the ventricular septal defect (VSD) has always been a management challenge. A 21-year-old male patient presented to the Cardiovascular surgery department with a restrictive perimembranous VSD with severe aortic regurgitation (AR). VSD was first diagnosed at 3 years of age. The surgical correction was decided when he was symptomatic of severe aortic regurgitation. Trans-aortic approach was performed to close the ventricular septal defect and correct the aortic regurgitation simultaneously. Surgical management was followed by a complete heart block.","PeriodicalId":397187,"journal":{"name":"Global Academic Journal of Medical Sciences","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139211340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}