中华眼科杂志最新文献

{"title":"[Chinese expert consensus on the diagnosis and treatment of herpes zoster keratitis (2025)].","authors":"","doi":"10.3760/cma.j.cn112142-20240905-00383","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240905-00383","url":null,"abstract":"<p><p>Varicella zoster virus keratitis (VZK) is a common infectious disease of the cornea. It has the clinical characteristics of multiple ocular tissue involvement, diverse corneal manifestations, and significant damage to corneal endothelial cells, and is prone to be misdiagnosed or missed. At present, a uniform diagnosis and treatment protocol of VZK is lacking at home and abroad. It is necessary to form consensus and guidance for accurate diagnosis and standardized treatment. The Ocular Infection Group of Chinese Ophthalmologist Association has facilitated relevant domestic experts, including corneal experts and dermatologists, to reach this consensus on the diagnosis, treatment, and prevention of VZK, on the basis of the previous publications, latest research progress, and expert clinical recommendations.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"61 2","pages":"87-95"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of corneal and conjunctival damage caused by suture exposure after buried-suture clouble-eyelid blepharoplasty].","authors":"S M Li, X Jin, N Zhang, H Zhang","doi":"10.3760/cma.j.cn112142-20240330-00152","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240330-00152","url":null,"abstract":"<p><p>A 52-year-old female patient experienced red eyes and eye pain for more than one year due to suture exposure in the left eye after double eyelid plasty with the embedding suture method. She visited several hospitals outside and was diagnosed with keratitis and conjunctival mass in the left eye. After anti-inflammatory and anti-infection treatments, the condition relapsed. She visited our hospital, and the exposed suture was removed. After a review half a year later, the conjunctival granuloma in the left eye disappeared, and the corneal ulcer lesion transformed into corneal pannus. This case suggests that ophthalmologists should conduct detailed eye examinations for patients with a history of double eyelid plasty, discover and handle suture exposure problems in time to improve prognosis.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"61 2","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Developing effective intervention strategies for congenital cataract to facilitate visual rehabilitation].","authors":"Z H Li, Z Ye, Y H Liu","doi":"10.3760/cma.j.cn112142-20240923-00413","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240923-00413","url":null,"abstract":"<p><p>Congenital cataract is a blinding condition that presents at birth. Form-deprivation amblyopia can be developed and has become the leading cause of childhood blindness in China. For the problems and challenges in the treatment of congenital cataract, this article discusses the surgical treatment and postoperative rehabilitation strategies and emphasizes the importance of developing effective intervention strategies to improve the visual outcomes in children with congenital cataract, providing valuable guidance for clinical treatment.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"959-963"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of capsular bag necrosis syndrome].","authors":"L Y Li, Z Ye, X H Guo, Y F Huang, Z H Li, Z Y Wang","doi":"10.3760/cma.j.cn112142-20240308-00098","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240308-00098","url":null,"abstract":"<p><p>A 58-year-old male patient presented with a 2-year history of blurred vision and eye discomfort in the right eye. The patient had a history of cataract surgery and glaucoma surgery. Upon admission, the unaided visual acuity of the right eye was 0.4, and the intraocular pressure was 33.4 mmHg (1 mmHg=0.133 kPa). The intraocular lens was decentered towards the nasal inferior direction, with a transparent capsular bag, no fibrous degeneration, or opacification observed. The patient underwent vitrectomy, intraocular lens suspension, and glaucoma valve implantation. During surgery, the capsular bag was found to be transparent and soft, and pathological examination revealed thinning of the capsular bag with very few epithelial cells. Postoperatively, the patient's unaided visual acuity in the right eye recovered to 0.8, and the intraocular pressure was controlled. Capsular bag necrosis syndrome is a recently proposed concept, characterized by an average age of onset of about 65.7 years, displacement of the intraocular lens years after IOL implantation, a transparent and soft capsular bag without fibrous proliferation, thinning and splitting/layering of the capsular bag, and no abnormalities in the zonules during the initial cataract surgery. The clinical and pathological features of this case are consistent with this syndrome, suggesting that this syndrome may be a new cause of intraocular lens displacement, and further research is needed on its pathogenesis and treatment measures.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"1013-1015"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application progress of micropulse wave transscleral laser treatment in glaucoma].","authors":"Q Y Ling, X Jia, F Nie, X C Duan","doi":"10.3760/cma.j.cn112142-20240131-00060","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240131-00060","url":null,"abstract":"<p><p>Glaucoma is the leading cause of blindness worldwide, and reducing intraocular pressure is crucial to delaying its progression. This review aims to explore the application progress of micropulse wave transscleral laser treatment (mTLT) in the treatment of glaucoma. This article introduces the evolution of ciliary body destructive surgical methods, and focuses on the mechanism of mTLT in the treatment of glaucoma, including reducing aqueous humor production, increasing the uveoscleral pathway and trabecular meshwork pathway for aqueous humor outflow. At the same time, the indications, contraindications, procedures and parameter settings of mTLT, its application effects in different types of glaucoma, possible complications, repeatability, and factors affecting the effect are discussed, and a comparison is made with the traditional TSCPC. However, the exact mechanism of mTLT in reducing intraocular pressure still needs to be further explored and clarified, and its related parameter settings still require a large number of clinical observations and studies.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"1022-1030"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress of single-cell RNA sequencing in ophthalmology].","authors":"J W Wang, J Qu, Y Li","doi":"10.3760/cma.j.cn112142-20240112-00024","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240112-00024","url":null,"abstract":"<p><p>Single-cell RNA sequencing is a cutting-edge genomic analysis technique performed at the individual cell level, offering researchers a powerful tool to investigate intercellular differences in gene expression and functional characteristics. In recent years, its application in ophthalmology has expanded rapidly, leading to numerous significant research outcomes. This review focuses on the latest advancements in single-cell RNA sequencing within the field of ophthalmology, summarizing its development, methodologies, advantages, limitations, and clinical relevance. The aim is to provide new insights into the pathogenesis of ocular diseases and the improvement of diagnostic and therapeutic strategies.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"1031-1038"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research advances on light-adjustable intraocular lens].","authors":"B Y Tu, J Yuan, Y Wang","doi":"10.3760/cma.j.cn112142-20240227-00083","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240227-00083","url":null,"abstract":"<p><p>Refractive error is a key determinant of visual acuity post-cataract surgery. Traditional methods for addressing refractive errors have been invasive, posing the risk of permanent surgical complications. Thus, the pursuit of non-invasive techniques for correcting refractive errors after cataract surgery is of significant clinical importance. Recently, a novel class of intraocular lenses (IOL), termed light-adjustable IOL, has emerged as a potential solution for refining refractive outcomes. These IOL possess the unique ability to alter their dioptric power in vitro through exposure to specific wavelengths of light, facilitating a non-invasive approach to refractive error correction. The landscape of light-adjustable IOL is diverse, encompassing ultraviolet light-adjustable IOL, novel nitinol-based thermomechanically adjustable IOL, IOL with refractive index changes induced by femtosecond lasers, and IOL utilizing two-photon effects for dioptric adjustment. This review article aims to summarize the advancements in light-adjustable lenses, providing insights and references for ongoing research and clinical practice in this field.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"1017-1021"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between type 2 diabetes mellitus and the risk of developing cataracts: based on the research of two-sample Mendelian randomization].","authors":"X H Jiang, B Zhang, W F Chen, Y E Zhao","doi":"10.3760/cma.j.cn112142-20240107-00005","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240107-00005","url":null,"abstract":"<p><p><b>Objective:</b> To determine the causal relationship between cataracts and type 2 diabetes mellitus (T2D) by the Mendelian randomization (MR) analysis using the genome-wide association study (GWAS) data. <b>Methods:</b> Data on T2D and cataracts in the European population were obtained from the OpenGWAS database. The single nucleotide polymorphisms (SNPs) that met the genome-wide significance criteria (<i>P</i><5×10⁻⁸) of T2D (48 286 cases, 250 671 controls) and cataracts (5 045 cases, 356 096 controls) were selected. The main method was random effects inverse variance weighting (IVW), and four other two-sample MR methods were also used, including MR Egger, Simple median, Weighted median, and Weighted mode, to assess the causal relationship using odds ratios (<i>OR</i>). Sensitivity analyses were conducted using the leave-one-out approach to evaluate the robustness of the results. <b>Results:</b> The MR Egger analysis showed a significant risk association between T2D and cataracts (<i>OR=</i>1.003, 95%<i>CI</i>=1.001-1.006; <i>P</i>=0.013). Using the methods of Weighted median (<i>OR</i>=1.002, 95%<i>CI</i>=1.000-1.004; <i>P</i>=0.029) and Weighted mode (<i>OR</i>=1.002, 95%<i>CI</i>=1.000-1.005; <i>P</i>=0.046), similar results were obtained. However, the IVW test failed to confirm the causality (<i>P</i>=0.149). The sensitivity analyses using the MR Egger and IVW tests did not show significant heterogeneity between T2D and cataracts (all <i>P</i>>0.05). With the leave-one-out analysis, the SNPs with significant effects were not identified, indicating the robustness of the MR results in this study. The MR Egger interception of the SNPs showed significant directional pleiotropy (<i>P</i>=0.038), suggesting a directional pleiotropy between T2D and cataracts. <b>Conclusions:</b> The results of the MR analysis suggest there is a causal relationship between T2D and cataracts, and T2D increases the risk of cataracts.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"991-997"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Correction of low to moderate corneal astigmatism by steep-axis incision in image-guided cataract surgery].","authors":"M Y Wang, C Liu, Y Zhang, Y Chen, Q Wu","doi":"10.3760/cma.j.cn112142-20240508-00211","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240508-00211","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To explore the corrective effect of cataract extraction surgery combined with a 2.8 mm steep-axis corneal incision under ophthalmic surgical navigation on low-to-moderate corneal astigmatism and different types of corneal astigmatism. &lt;b&gt;Methods:&lt;/b&gt; A prospective cohort study was conducted. Patients with age-related cataract who underwent cataract extraction combined with single-focus intraocular lens implantation in the Department of Ophthalmology at the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from June to October 2023 and had a total corneal regular astigmatism degree of ≥0.50 D and &lt;1.50 D were continuously collected. Patients were divided into a low-degree group (&lt;1.00 D) and a moderate-degree group (≥1.00 D) according to corneal astigmatism degree. Simultaneously, they were classified into with-the-rule (WTR), against-the-rule (ATR), and oblique astigmatism based on preoperative corneal astigmatism axis position. Subjective refraction and anterior segment biometer examination were performed before and 3 months after surgery, respectively. Vector analysis of corneal astigmatism was conducted using the Alpins vector analysis method. The main observational indicators included target induced astigmatism, surgically induced astigmatism, and the correction index. &lt;b&gt;Results:&lt;/b&gt; A total of 95 patients (110 eyes) were collected in this study. Thirteen patients (18 eyes) were lost to follow-up, and finally 82 patients (92 eyes) were included. In the low-degree group, there were 14 males (16 eyes) and 26 females (23 eyes), with an age of (69.62±12.22) years. In the moderate-degree group, there were 13 males (15 eyes) and 33 females (35 eyes), with an age of (72.98±8.28) years. The target astigmatism correction amount, surgically induced astigmatism, and deviation vector in the low-degree group were all smaller than those in the moderate-degree group (all &lt;i&gt;P&lt;/i&gt;&lt;0.05). Postoperative corneal astigmatism in both groups was undercorrected. The correction index in the low-degree group (0.88±0.44) was greater than that in the moderate-degree group (0.59±0.34) (&lt;i&gt;P&lt;/i&gt;=0.001), and the undercorrection proportion in the moderate-degree group (90.00%, 45/50) was much higher than that in the low-degree group (57.14%, 24/42). In the low-degree group, the correction index from high to low was WTR (1.07±0.41), oblique (0.90±0.58), and ATR astigmatism eyes (0.69±0.37). After multiple comparison analysis, the correction index of WTR astigmatism eyes was significantly higher than that of ATR astigmatism eyes (&lt;i&gt;P&lt;&lt;/i&gt;0.05). The success index from high to low was oblique (0.82±0.57), ATR (0.74±0.39), and WTR astigmatism eyes (0.68±0.43). In the moderate-degree group, the order of the correction index from high to low was the same as that in the low-degree group, also WTR (0.79±0.33), oblique (0.71±0.50), and ATR astigmatism eyes (0.53±0.30), but there was no statistical significance among the ","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"977-984"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Observation on the efficacy of cataract surgery combined with ICL implantation in the contralateral eye for patients with high myopia complicated with monocular cataract].","authors":"J Zhou, J Ye","doi":"10.3760/cma.j.cn112142-20240313-00111","DOIUrl":"https://doi.org/10.3760/cma.j.cn112142-20240313-00111","url":null,"abstract":"<p><p><b>Objective:</b> To assess the surgical outcomes of cataract surgery combined with phakic posterior chamber intraocular lens (ICL) implantation in the contralateral eye for patients with high myopia and monocular cataract. <b>Methods:</b> This is a retrospective case series study. Clinical data were collected from 10 patients (20 eyes) with high myopia and monocular cataract who underwent phacoemulsification cataract extraction and intraocular lens implantation in the cataract eye (cataract surgery eye), and implantable Collamer lens (ICL) implantation in the contralateral eye (ICL implantation eye) at the Ophthalmology Department of the Army Characteristic Medical Center from June 2021 to December 2023. Among them, there were 4 males and 6 females, with an average age of (35.60±7.62) years. Uncorrected visual acuity was measured using the international standard visual acuity chart, and spherical equivalent (SE) and best corrected visual acuity (BCVA) were obtained through comprehensive optometry. Visual acuity was recorded in the form of logarithm of the minimum angle of resolution (logMAR). Objective visual quality parameters were obtained using a visual quality analysis system, and subjective visual quality was obtained through questionnaire surveys. Postoperative accommodative function and defocus curve were also examined. Various indicators before and 5 months after surgery were compared between the two eyes. <b>Results:</b> The BCVA in the cataract surgery eye significantly improved postoperatively (<i>P</i><0.05), while no significant change was observed in the ICL implantation eye (<i>P</i>>0.05). Postoperative UCVA for the cataract surgery eye was 0.12±0.12 for distance, 0.18±0.18 for intermediate, and 0.28±0.20 for near vision. For the ICL implantation eye, these values were 0.10±0.11, 0.00 (0.00, 0.03), and 0.01 (0.00, 0.06), respectively. Objective scatter indices postoperatively were 2.20±1.82 for the cataract surgery eye and 0.90 (0.48, 1.90) for the ICL implantation eye. All patients became spectacle-independent postoperatively, with 6 experiencing halo phenomena that did not affect their daily life. The average patient satisfaction score was 9.5. The ICL implantation eye showed better accommodative amplitude and facility than the cataract surgery eye, with statistically significant differences (both <i>P</i><0.05). The defocus curve indicated good binocular visual acuity, and no severe intraoperative or postoperative complications were reported. <b>Conclusions:</b> For patients with high myopia and monocular cataract, the combination of cataract surgery and ICL implantation in the contralateral eye effectively enhances postoperative visual acuity and quality, preserves natural accommodation, establishes binocular vision balance, and facilitates spectacle independence. The procedure is safe, reliable, and improves the quality of life and work.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"60 12","pages":"985-990"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}