Kobe Journal of Medical Sciences最新文献_第4页

The Association of Anti-dsDNA Antibodies with Patient-reported Outcomes of Patients with Systemic Lupus Erythematosus in a Two-consecutive Year Prospective Study. 在一项连续两年的前瞻性研究中，抗dsdna抗体与系统性红斑狼疮患者报告的预后的关系

Kobe Journal of Medical Sciences Pub Date : 2025-02-03 DOI: 10.24546/0100492949

Yuto Nakakubo, Hideaki Tsuji, Yudai Takase, Tsuneyasu Yoshida, Tomohiro Kozuki, Takeshi Iwasaki, Mirei Shirakashi, Hideo Onizawa, Ryosuke Hiwa, Koji Kitagori, Shuji Akizuki, Ran Nakashima, Akira Onishi, Hajime Yoshifuji, Masao Tanaka, Akio Morinobu

{"title":"The Association of Anti-dsDNA Antibodies with Patient-reported Outcomes of Patients with Systemic Lupus Erythematosus in a Two-consecutive Year Prospective Study.","authors":"Yuto Nakakubo, Hideaki Tsuji, Yudai Takase, Tsuneyasu Yoshida, Tomohiro Kozuki, Takeshi Iwasaki, Mirei Shirakashi, Hideo Onizawa, Ryosuke Hiwa, Koji Kitagori, Shuji Akizuki, Ran Nakashima, Akira Onishi, Hajime Yoshifuji, Masao Tanaka, Akio Morinobu","doi":"10.24546/0100492949","DOIUrl":"10.24546/0100492949","url":null,"abstract":"Objectives: To analyse the association of anti-dsDNA Ab with patient-reported outcomes (PROs) in patients with SLE under maintenance treatment, as it has not been clearly understood whether PROs are able to be reflected by anti-dsDNA, which are associated with SLE activities (SLE Disease Activity Index 2000, SLEDAI-2K).Methods: The SLE symptom checklist (SSC), LupusPRO, Medical Outcomes Study Short Form-36 (SF-36), and patient and physician visual analogue scale (Pt/Ph-VAS) at a time point were evaluated for correlation with anti-dsDNA using the Kyoto Lupus Cohort Registry (n = 310) from 2019 to 2020. Further, associations between changes in anti-dsDNA with those in Pt/Ph-VAS and SSC at two time points of short-term (3 months) or long-term (2 years) time points.Results: Cross-sectionally, anti-dsDNA slightly correlated with Ph-VAS (ρ = 0.18, p = 0.003) and SLEDAI-2K (ρ = 0.14, p = 0.03), while anti-dsDNA was not correlated with SSC, SF-36, and LupusPRO, or Pt-VAS. In short-term and long-term, anti-dsDNA demonstrated no significant correlation with alterations in SSC, Pt-VAS, or Ph-VAS. Further, they did not show associations when SLE activities (SLEDAI-2K) were worsened.Conclusion: PROs at a time point and changes were difficult to be captured by anti-dsDNA. It is desirable to explore objective laboratory measures to evaluate PROs.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 4","pages":"E113-E124"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of SARS-CoV-2 Infection in Patients with Neuromuscular Disease and Inborn Errors of Metabolism: A Cross-sectional Study for a Pediatric Outpatient Referral in Japan. 神经肌肉疾病患者中SARS-CoV-2感染和先天性代谢错误的流行病学：日本儿科门诊转诊的横断面研究

Kobe Journal of Medical Sciences Pub Date : 2025-02-03 DOI: 10.24546/0100492945

Sungwon Hong, Kiiko Iketani, Shoko Sonehara, Hiroaki Hanafusa, Yoshinori Nambu, Kandai Nozu, Hiroyuki Awano, Ryosuke Bo

{"title":"Epidemiology of SARS-CoV-2 Infection in Patients with Neuromuscular Disease and Inborn Errors of Metabolism: A Cross-sectional Study for a Pediatric Outpatient Referral in Japan.","authors":"Sungwon Hong, Kiiko Iketani, Shoko Sonehara, Hiroaki Hanafusa, Yoshinori Nambu, Kandai Nozu, Hiroyuki Awano, Ryosuke Bo","doi":"10.24546/0100492945","DOIUrl":"10.24546/0100492945","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic has affected people worldwide, and pediatric patients with underlying diseases are at high risk of developing severe COVID-19. However, there are limited reports on the clinical impact of COVID-19, especially in patients with underlying neuromuscular diseases (NMD) and inborn errors of metabolism (IEM). This study aimed to investigate the incidence and clinical presentation of COVID-19 in patients with NMD and IEM. This was a single-center, cross-sectional study of patients with NMD and IEM in Japan for 2 years, from April 1, 2020 to March 31, 2022. Among 255 participants with a median age of 14 (range: 0-50) years, 192 (75%) and 63 (25%) had NMD and IEM, respectively. Among 255 patients, 8 (5 NMD and 3 IEM) were positive for the anti-severe acute respiratory syndrome coronavirus 2 nucleocapsid antibody, and the incidence was considered 3%. All positive patients had mild or asymptomatic COVID-19. None of the patients exhibited moderate or severe symptoms. In conclusion, this study revealed that the incidence of COVID-19 was low, and mild or subclinical infection was common even in patients with NMD and IEM, who may be at a higher risk of severe COVID-19.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 4","pages":"E106-E112"},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Liver Fibrosis Using Shear Wave Elastography after Surgery for Congenital Biliary Dilatation. 利用剪切波弹性成像技术评估先天性胆道扩张手术后的肝纤维化情况

Kobe Journal of Medical Sciences Pub Date : 2024-11-21 DOI: 10.24546/0100492148

Yudai Tsuruno, Hiroaki Fukuzawa, Mitsumasa Okamoto, Toshifumi Tada

{"title":"Evaluation of Liver Fibrosis Using Shear Wave Elastography after Surgery for Congenital Biliary Dilatation.","authors":"Yudai Tsuruno, Hiroaki Fukuzawa, Mitsumasa Okamoto, Toshifumi Tada","doi":"10.24546/0100492148","DOIUrl":"10.24546/0100492148","url":null,"abstract":"Purpose: Liver fibrosis is not thought to occur in patients with no adverse events after surgery for congenital biliary dilatation (CBD). However, this speculation is not supported by any reports. Real-time shear wave elastography (SWE) is a noninvasive, ultrasound-based technique to evaluate liver stiffness. We aimed to clarify the presence of liver fibrosis using SWE in patients who had undergone surgery for CBD.Methods: We included patients who underwent radical surgery for CBD, who were followed up until March 2022, and have been performed with SWE at our institution from April 2021 to March 2022. Liver stiffness was evaluated using SWE, and liver fibrosis stages (F0-F4; METAVIR scoring) were determined based on the previously reported associations between liver stiffness and liver fibrosis. We assessed the general condition of each patient and performed routine blood investigations on the same day as SWE.Results: Two out of 20 patients had long-term complications (intrahepatic stones without symptoms [n = 1], recurrent cholangitis [n = 1]). The median hepatic shear wave propagation velocity was 1.26 (range, 1.12-1.60) m/s in all cases. The estimated liver fibrosis stage was ≤F1 in patients without long-term complications. In patient with recurrent cholangitis, the hepatic shear wave propagation velocity was 1.60 m/s, and the estimated liver fibrosis stage was F3.Conclusion: Liver fibrosis tended not to occur in patients with no complications after surgery for CBD. However, patients with long-term postoperative complications, such as cholangitis, should be examined using SWE so as not to overlook liver cirrhosis.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 3","pages":"E100-E105"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of a Home-visit Nursing Agency in Supporting Patients with Heart Failure on Continuous Catecholamine Infusion: A Case Series Study. 家访护理机构在支持持续输注儿茶酚胺的心力衰竭患者中的作用：病例系列研究。

Kobe Journal of Medical Sciences Pub Date : 2024-10-16 DOI: 10.24546/0100491788

Takemasa Ishikawa, Ryoko Sekiguchi, Tomoko Shimizu, Yuka Fukata, Reiko Kanaya, Kumiko Katsuma

{"title":"Role of a Home-visit Nursing Agency in Supporting Patients with Heart Failure on Continuous Catecholamine Infusion: A Case Series Study.","authors":"Takemasa Ishikawa, Ryoko Sekiguchi, Tomoko Shimizu, Yuka Fukata, Reiko Kanaya, Kumiko Katsuma","doi":"10.24546/0100491788","DOIUrl":"10.24546/0100491788","url":null,"abstract":"Aim: This study aimed to discuss the role of home-visit nurses in managing continuous catecholamine infusion in patients with heart failure by investigating the outcome of patients and the home-visit nursing intervention.Methods: We conducted a retrospective, case series study of eight patients with heart failure who underwent home-based continuous catecholamine infusion between April 2016 and March 2024. Data including the patients' demographics, the duration of continuous catecholamine infusion, the frequency of nursing and emergency nursing visits, and patients' endpoints were collected.Results: The median age of the patients was 68.5 (interquartile range: 51.8-80.0) years and 75% were men. The most common diagnosis requiring home-based catecholamine infusion was dilated cardiomyopathy. The median duration of continuous catecholamine infusion in the patients was 58.0 days. The median frequency of nursing visits was 8.4 times each week. Forty-five emergency nursing visits occurred, and the most common reason for these visits was managing infusion device malfunctions. Among the patients, six died at home, one was hospitalized owing to fatal arrhythmia, and one withdrew from continuous catecholamine infusion.Conclusion: This study shows the complexities of providing home-based care for patients with heart failure requiring continuous catecholamine infusion. Most patients with heart failure were able to spend the rest of their lives at home, despite the challenges of managing such a treatment outside the hospital. Our findings indicate the need for early intervention, multidisciplinary collaboration, and the development of home care protocols to optimize treatment efficacy and the quality of life of these patients.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 3","pages":"E93-E99"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Japanese Case of Food Protein-induced Enterocolitis Syndrome Caused by Multiple Seafoods. 日本一例由多种海产品引起的食物蛋白诱发小肠结肠炎综合征病例

Kobe Journal of Medical Sciences Pub Date : 2024-08-05 DOI: 10.24546/0100490906

Taiki Satou, Saeko Yamamura, Akari Takahashi, Seiichi Tawaza, Kyoko Ozawa, Yoshiko Tanaka, Hiroshi Asada

引用次数: 0

Comparison over Time of Adverse Drug Reactions in Diabetes Patients Treated with Sodium-Glucose Cotransporter 2 Inhibitors. 使用钠-葡萄糖共转运体 2 抑制剂治疗糖尿病患者的药物不良反应随时间变化的比较。

Kobe Journal of Medical Sciences Pub Date : 2024-07-25 DOI: 10.24546/0100490464

Mai Ueda, Masako Zenibayashi, Tomoko Yamada, Shun-Ichiro Asahara, Wataru Ogawa

{"title":"Comparison over Time of Adverse Drug Reactions in Diabetes Patients Treated with Sodium-Glucose Cotransporter 2 Inhibitors.","authors":"Mai Ueda, Masako Zenibayashi, Tomoko Yamada, Shun-Ichiro Asahara, Wataru Ogawa","doi":"10.24546/0100490464","DOIUrl":"10.24546/0100490464","url":null,"abstract":"Backgrounds: The prescription of sodium-glucose cotransporter-2 (SGLT2) inhibitors have been increasing due to their additional benefits, including weight loss, cardioprotection and renoprotection. Accordingly, there are concerns about the potential rise in severe adverse drug reactions (ADRs), such as urinary tract infections, diabetic ketoacidosis, volume depletion, and hypoglycemia. The Society has announced recommendations on the proper use of SGLT2 inhibitors. We aimed to elucidate the recent occurrence of severe ADRs which need discontinuation of SGLT2 inhibitors or hospitalization.Methods: In this retrospective cohort study, we identified 391 diabetic patients who were prescribed SGLT2 inhibitors upon admission to our hospital between April 2017 and March 2023. Of these, 68 patients who discontinued SGLT2 inhibitors for reasons other than ADRs were excluded. Patients were classified into the 2017 group and the 2020 group based on the treatment period of SGLT2 inhibitors, and the occurrence of ADRs and patient backgrounds were compared between the two groups.Results: A total of 323 eligible patients were identified. Discontinuations of SGLT2 inhibitors decreased in the 2020 group (p < 0.05). However, discontinuations due to frailty increased (p < 0.05). Hospitalization due to ADRs, specifically those due to urinary tract infections, diabetic ketoacidosis, or volume depletion, did not specifically decrease (p = 0.273).Conclusions: This study indicated that there has been some improvement in the awareness of the proper use of SGLT2 inhibitors and there is still a need to continue enlightenment activities.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 3","pages":"E81-E88"},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Difficulty in Removing a Ureteral Stent post Childbirth due to Encrustation: A Case Report. 分娩后因包壳而难以取出输尿管支架：病例报告。

Kobe Journal of Medical Sciences Pub Date : 2024-07-01 DOI: 10.24546/0100490328

Masato Yanagi, Hiroyoshi Kono, Hiroyuki Muramatsu, Akifumi Katsu, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

引用次数: 0

X-ray Pelvimetry Has No Impact on the Outcomes of Trial of Labor after Cesarean Delivery: A Retrospective Single-center Study. X 射线骨盆测量对剖宫产后试产的结果没有影响：一项回顾性单中心研究

Kobe Journal of Medical Sciences Pub Date : 2024-06-19 DOI: 10.24546/0100490211

Maya Komatsu, Yoshitsugu Chigusa, Ryusuke Murakami, Masahito Takakura, Masaki Mandai, Haruta Mogami

{"title":"X-ray Pelvimetry Has No Impact on the Outcomes of Trial of Labor after Cesarean Delivery: A Retrospective Single-center Study.","authors":"Maya Komatsu, Yoshitsugu Chigusa, Ryusuke Murakami, Masahito Takakura, Masaki Mandai, Haruta Mogami","doi":"10.24546/0100490211","DOIUrl":"10.24546/0100490211","url":null,"abstract":"Few studies have examined the relationship between pelvic size and the success or failure of trial of labor after cesarean delivery (TOLAC). Here we aimed to determine whether pelvic size and morphological data obtained from radiography contribute to the first successful TOLAC. This retrospective single-center observational study enrolled pregnant women who underwent TOLAC between 2010 and 2021. The results of X-ray pelvimetry data, including obstetric conjugate (OC), transverse diameter of the pelvic inlet (TD), anteroposterior diameter of the pelvic inlet (APD), shape of the pelvic inlet, and other obstetrical clinical data, were compared between the success and failure groups. Seventy-five patients in successful group after excluding 35 patients with previous successful TOLAC, and 21 patients in failure group were eligible. The failure group had a higher rate of previous cesarean sections due to failed labor trials (p = 0.042) and heavier newborns (p = 0.014). OC, TD, and APD on X-ray pelvimetry did not differ significantly between the two groups nor did the shape of the pelvic inlet affect the success rate for TOLAC. The generalized linear model identified a history of failed trials of labor as a significant predictor of failed TOLAC (odds ratio, 0.26; 95% confidence interval 0.071-0.923; p = 0.037), whereas no pelvimetric parameters were found. Pelvic size and morphological findings have no discernible impact on the outcomes of TOLAC. The universal application of X-ray pelvimetry in all women attempting TOLAC may not have significant clinical relevance.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 2","pages":"E70-E76"},"PeriodicalIF":0.0,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of an Extremely Preterm Infant with Intussusception Triggered by Acquired Cytomegalovirus Infection. 一例获得性巨细胞病毒感染引发肠套叠的极早产儿。

Kobe Journal of Medical Sciences Pub Date : 2024-06-12 DOI: 10.24546/0100489974

Sanae Naito, Sachiyo Fukushima, Tomoaki Ioroi, Chie Sakata, Daisuke Kurokawa, Tsuyoshi Egawa, Yudai Tsuruno, Mitsumasa Okamoto, Hiroaki Fukuzawa, Masaaki Kugo

{"title":"A Case of an Extremely Preterm Infant with Intussusception Triggered by Acquired Cytomegalovirus Infection.","authors":"Sanae Naito, Sachiyo Fukushima, Tomoaki Ioroi, Chie Sakata, Daisuke Kurokawa, Tsuyoshi Egawa, Yudai Tsuruno, Mitsumasa Okamoto, Hiroaki Fukuzawa, Masaaki Kugo","doi":"10.24546/0100489974","DOIUrl":"10.24546/0100489974","url":null,"abstract":"Intussusception is a common cause of intestinal obstruction in infants aged 6-18 months. However, intussusception in preterm neonates (IPN) is an exceedingly rare disorder. The etiology of IPN remains unclear, but common prenatal injuries, such as those causing intestinal hypoxia/hypoperfusion, dysmotility, and strictures, have been proposed as possible contributing factors. Diagnosis is often delayed because the symptoms closely resemble those of necrotizing enterocolitis (NEC). Given the divergent treatments for IPN and NEC, establishing an early and accurate diagnosis is crucial. IPN is predominantly located in the small intestine (91.6%), and ultrasonography proves useful in its diagnosis. We present a case of a very preterm infant who developed intussusception triggered by acquired cytomegalovirus (aCMV) infection, necessitating surgical treatment. The cause of intussusception in this case was diagnosed as aCMV enteritis because no organic lesions were observed in the advanced part of the intussusception. The presence of CMV was confirmed by CMV-DNA-PCR examination of the resected intestinal tract. Intestinal edema and decreased intestinal peristalsis due to aCMV enteritis are likely the primary causes of the intussusception.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 2","pages":"E66-E69"},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxygenation and Carbon Dioxide Rebreathing of a Well-fitting Non-rebreathing EcoLite™ Mask with a Reservoir: A Single-center Prospective Observational Study in Healthy Volunteers. 带储气罐的舒适型非呼吸式 EcoLite™ 面罩的吸氧和二氧化碳再呼吸：健康志愿者的单中心前瞻性观察研究。

Kobe Journal of Medical Sciences Pub Date : 2024-06-03 DOI: 10.24546/0100489920

Yusuke Miyazaki, Joji Kotani

{"title":"Oxygenation and Carbon Dioxide Rebreathing of a Well-fitting Non-rebreathing EcoLite™ Mask with a Reservoir: A Single-center Prospective Observational Study in Healthy Volunteers.","authors":"Yusuke Miyazaki, Joji Kotani","doi":"10.24546/0100489920","DOIUrl":"10.24546/0100489920","url":null,"abstract":"Background: The fitting of oxygen mask affects the performance of it such as oxygenation or CO₂ elimination. The intersurgical EcoLite™ adult high-concentration oxygen mask (EcoLite with a reservoir, Intersurgical, UK) was developed to give well-fitting. The purpose of this study is to evaluate the performance of EcoLite with a reservoir compared to the conventional mask.Methods: Ten healthy volunteers were included in this study. EcoLite with a reservoir and conventional mask were given to patients at different oxygen flow rates (5, 8, 10, 12, and 15 L/min). Fraction of inspiratory O₂ (FIO₂) and partial pressure of inspiratory CO₂ (PICO₂) were measured by a sampling tube at the middle pharynx inserted via nose.Results: The EcoLite with a reservoir had a significantly higher FIO₂ than the control reservoir mask. However, the PICO₂ was significantly higher in the EcoLite with a reservoir than in the control reservoir mask, especially when the oxygen flow rate was low.Conclusion: The EcoLite with a reservoir provided improved oxygenation and a better fit than the conventional reservoir masks in healthy volunteers. However, the EcoLite with a reservoir might cause higher CO₂ rebreathing at low oxygen flow rates.","PeriodicalId":39560,"journal":{"name":"Kobe Journal of Medical Sciences","volume":"70 2","pages":"E61-E65"},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0