Brazilian Journal of Oncology最新文献

{"title":"Protein carbonyl products, malondialdehyde, glutathione and vitamins C/E of breast cancer patients subjected to chemotherapy","authors":"M. L. R. Paraboni, Jaíne Kalinoski, Bianca Genovefa Braciak, Adriana Elisa Wilk, Laura Smolski dos Santos, E. G. Schmitt, V. Manfredini, I. Gonçalves","doi":"10.5935/2526-8732.20220302","DOIUrl":"https://doi.org/10.5935/2526-8732.20220302","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"02 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129438594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous nephrostomy in cervical cancer patients: a retrospective analysis","authors":"Débora de A A Lima, Carolina do Nascimento Matias Teixeira, M. Abath, Fernando Antonio Nunes Raposo, Silvia Borges Fontan","doi":"10.5935/2526-8732.20230393","DOIUrl":"https://doi.org/10.5935/2526-8732.20230393","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131404205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-sectional study of 1-to-5- year head and neck cancer survivors","authors":"P. Cruvinel, Raony Môlim de Sousa Pereira, André Luiz de Macedo Fressatti, Bianka Jurca Gonçalves da Motta, A. C. Motta, H. Oliveira, H. Ricz, L. D. Macedo, C. Tirapelli","doi":"10.5935/2526-8732.20220316","DOIUrl":"https://doi.org/10.5935/2526-8732.20220316","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132951691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe prescription of systemic antineoplastic treatment in oncology: integrative literature review","authors":"Fabiola Vasconcelos Alves, R. C. Silveira, Flávia Oliveira de Almeida Marques da Cruz, E. B. Ferreira, P. E. D. D. Reis","doi":"10.5935/2526-8732.20220300","DOIUrl":"https://doi.org/10.5935/2526-8732.20220300","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"34 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132173023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PARP inhibitors as first-line maintenance therapy in ovarian cancer: recommendations from an expert panel from Brazil","authors":"Aknar F. C. Calabrich, D. Assad, Graziela Dal-Molin, A. Melo, A. Nogueira-Rodrigues, K. Kalil, Andrea PG Guimarães, Michelle Samora Almeida, Carla Rameri de-Azevedo, Daniela de-Freitas, A. Morelle, A. C. Leite, M. Crosara, J. Nunes, Poliana A. Signorini, E. Cronemberger, R. Cossetti, Rodrigo Guindalini, E. Paulino, F. Maluf","doi":"10.5935/2526-8732.20230400","DOIUrl":"https://doi.org/10.5935/2526-8732.20230400","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114154882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on complete pathological response and estimated survival among breast cancer patients undergoing neoadjuvant chemotherapy in a private institution in the state of Rio de Janeiro","authors":"L. Sermoud, M. Gaui, T.A.V. Ferreira, L. Lerner, G. Buscacio, D. Pagnoncelli, L. Araujo","doi":"10.5935/2526-8732.20210026","DOIUrl":"https://doi.org/10.5935/2526-8732.20210026","url":null,"abstract":"Objective: Breast cancer is the most common malignancy among women, both in developed and in developing countries. Indications for neoadjuvant treatment have been expanded so that pathological responses can be evaluated. Diversified therapeutic approaches may thus be indicated in accordance with each residual disease profile. This was a real-life study, in which the aim was to analyze the complete pathological response (CPR) and estimated survival among breast cancer patients undergoing neoadjuvant chemotherapy in a private institution in the state of Rio de Janeiro. Methods: This was a prospective observational cohort study on patients diagnosed with breast cancer and treated with neoadjuvant chemotherapy, in a private institution. The primary objective of this study was to analyze CPR. As secondary endpoints, we evaluated the disease-free survival (DFS) and overall survival (OS) of these patients and correlated them with clinical-pathological variables. Results: CPR was achieved in: 12.5% of luminal A cases; 19.5% of luminal B/HER-2-negative cases; 38.5% of luminal B/ HER-2-positive cases; 65% of HER-2-enriched cases; and 37.8% of triple negative cases. There was a significant correlation between CPR and histopathological subtypes (p<0.001). At the end of 36 months, the DFS for patients with CPR was 89.1% vs. 72.4% for the others (p=0.01). OS could not be calculated for patients who achieved CPR, because there was no event. Conclusion: We confirmed in this study that a correlation exists between CPR and overall survival. In addition, we were able to show that even in developing countries, such as Brazil, appropriate treatments can be offered in accordance with international guidelines, such that our results were consequently similar to those in the worldwide literature. ABSTRACT significativa entre a RCP e os subtipos histopatológicos (p<0,001). Ao final de 36 meses, a DFS para pacientes com RCP foi de 89,1% vs. 72,4% para os demais (p=0,01). SG não pôde ser calculado para pacientes que alcançaram RCP, porque não houve nenhum evento. Conclusão: Confirmamos neste estudo que existe uma correlação entre a RCP e a sobrevida global. Além disso, pudemos mostrar que mesmo em países em desenvolvimento, como o Brasil, tratamentos adequados podem ser oferecidos de acordo com as diretrizes internacionais, de forma que nossos resultados foram, consequentemente, semelhantes aos da literatura mundial.","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121908339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy alone in locally advanced cervical cancer: a palliative treatment? Real-world data","authors":"T. Braz, E. Paulino, A. Garces, Rachele Grazziotin Reisner, G. Guitmann, L. Thuler, A. Melo","doi":"10.5935/2526-8732.20210014","DOIUrl":"https://doi.org/10.5935/2526-8732.20210014","url":null,"abstract":"Objective: To investigate the benefit of radiotherapy alone in patients diagnosed with locally advanced cervical cancer when the addition of chemotherapy was contraindicat ed. Methods: A single-center cohort study of patients diagnosed with locally advanced cervical cancer as defined by the FIGO 2009 (stage IB2 to IVA) and contraindication for concomitant chemotherapy was retrospectively evaluated. Patients included were treated with radiotherapy in a curative intent and those patients who completed the external beam radiotherapy were considered for brachytherapy. Patient’s demographics, reasons for not receiving concomitant chemotherapy and treatment responses were analyzed. Disease-free survival (DFS) and overall survival (OS) were calculated. Results: With a median follow-up of 13.9 months (range 0.10-81.8), the median DFS was 11.6 months (95% CI: 10.2-13.1), and the median OS was 15.9 months (95% CI: 11.5-20.3). Conclusion: This real-world study provides descriptive information confirming that radiotherapy with cura tive intent should be offered to patients with locally advanced cervical cancer even when chemotherapy is not an option due to clinical or laboratory contraindications. ABSTRACT","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122315710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brazilian cohort results of the PRECONNECT study: safety and efficacy of trifluridine/tipiracil in metastatic colorectal cancer","authors":"C. Mello, F. Cruz, F. M. Vieira, A. Azambuja, L. A. Leite, Luciana Mardega, Andreia Gil, L. Vidot, A. Coutinho","doi":"10.5935/2526-8732.20220364","DOIUrl":"https://doi.org/10.5935/2526-8732.20220364","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"283 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115263451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: a rare mediastinal neuroblastoma in an adult associated with syndrome of inappropriate secretion of antidiuretic hormone (SIADH)","authors":"C. S. Souza, Carine Matos Bispo Patury, José Slaibi Filho, P. Athanazio, Lister Cedro Ramos, J. M. Nassri, Laíse Oliveira Pales Santos, Carina Manuela Souza Barreto, Michelle Oliveira Espírito-Santo, Laiane Campos Pereira, Marianna Santos Rodrigues","doi":"10.5935/2526-8732.20230405","DOIUrl":"https://doi.org/10.5935/2526-8732.20230405","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116586634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental finding of sex cord tumor with annular tubules in ovary associated with Peutz-Jeghers syndrome","authors":"N. B. Corrêa, Laura Paggiarin Skonieski, F. Lemanski, R. Baldissera","doi":"10.5935/2526-8732.20220343","DOIUrl":"https://doi.org/10.5935/2526-8732.20220343","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117212880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}