Polski Merkuriusz Lekarski最新文献_第9页

International standards for conducting biomedical research with human participation. 开展有人类参与的生物医学研究的国际标准。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202405118

Ivan Ye Peresh, Dmytro D Petsa, Vasyl V Kopcha, Tetyana M Silina

{"title":"International standards for conducting biomedical research with human participation.","authors":"Ivan Ye Peresh, Dmytro D Petsa, Vasyl V Kopcha, Tetyana M Silina","doi":"10.36740/Merkur202405118","DOIUrl":"10.36740/Merkur202405118","url":null,"abstract":"Objective: Aim: To conduct a comprehensive analysis and systematization of international standards for biomedical research involving human participants, to identify their key principles and implementation mechanisms, as well as to evaluate their effectiveness in ensuring ethical and legal norms during such research..Patients and methods: Materials and Methods: This research employs a diverse array of scientific inquiry methods, encompassing both general scientific approaches and specialized techniques.Conclusion: Conclusions: The Declaration of Helsinki is a combination of ethical principles for conducting medical research with the participation of people. Taking into account the evolution of global and practical provisions on this issue, it is quite natural that certain points of the declaration were revised, supplemented, improved and generally contain a list of ethical rules of medical practice, one of which states: \"The duty of a doctor is to improve and protect health people, including patients participating in medical research. His knowledge and conscience must be directed to the service of this duty.\"","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 5","pages":"593-597"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selected possibilities of physical medicine versus cancer diseases. 物理医学与癌症疾病的若干可能性。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202405119

Dominik Dziadek, Aleksander Sieroń

{"title":"Selected possibilities of physical medicine versus cancer diseases.","authors":"Dominik Dziadek, Aleksander Sieroń","doi":"10.36740/Merkur202405119","DOIUrl":"https://doi.org/10.36740/Merkur202405119","url":null,"abstract":"Objective: Aims: This review aims to synthesize the latest literature on physical treatments for wounds, focusing on the use of ozone therapy, topical oxygen therapy, pulsed electromagnetic field therapy, and red light therapy in oncology patients. It evaluates the indications, benefits, and contraindications of these therapies, especially concerning cancer..Patients and methods: Materials and Methods: A literature search was conducted in publicly available online databases, covering publications in English and Polish from 2010 to 2024. The inclusion criteria comprised clinical trials, systematic reviews, meta-analyses, and review articles on physical treatments for wounds in oncology patients. The selection process involved pre-selection, title and abstract review, and full-text review to ensure compliance with the inclusion criteria. Data were analyzed to identify mechanisms of action, therapeutic efficacy, and potential risks associated with these therapies in oncology patients. Ozone therapy showed potential in reducing bacterial load and tumor hypoxia, enhancing chemotherapy efficacy. Topical oxygen therapy was effective for chronic wounds, with careful application near tumor sites. Pulsed electromagnetic field therapy demonstrated promising anticancer effects, inducing apoptosis in cancer cells. Red light therapy, while beneficial for managing side effects of cancer treatments, was contraindicated in areas with active tumors due to the risk of stimulating cancer cell proliferation.Conclusion: Conclusions: Physical therapies offer benefits in wound management but require careful consideration in oncology patients. Personalized evaluation and further research are essential to establish safe and effective protocols for oncology patients, maximizing therapeutic benefits while minimizing risks.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 5","pages":"598-603"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative acute kidney injury - cloaked and hidden - know your enemy. 围手术期急性肾损伤——隐蔽的和隐藏的——知道你的敌人。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202405117

Przemysław Janusz Bolewski, Janusz Trzebicki

引用次数: 0

Effectiveness of a skill lab on nursing students' knowledge to perform peripherally inserted central catheter insertion: a quasi-experimental study.

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202406108

Ioannis Kouroutzis, Maria Malliarou

{"title":"Effectiveness of a skill lab on nursing students' knowledge to perform peripherally inserted central catheter insertion: a quasi-experimental study.","authors":"Ioannis Kouroutzis, Maria Malliarou","doi":"10.36740/Merkur202406108","DOIUrl":"https://doi.org/10.36740/Merkur202406108","url":null,"abstract":"Objective: Aim: To evaluate the knowledge and confidence of nursing students of a Greek university related to Peripherally Inserted Central Catheter (PICC) insertion and care..Patients and methods: Materials and Methods: A quasi-experimental study using a one-group pretest-posttest design consistent with Transparent Reporting of Evaluations with Nonrandomized Designs guidelines. The study was conducted in a university laboratory in March 2024. Participants were followed before and after the training lab. The lab involved 80 nursing students. For the comparison of evaluation score before and after the intervention Mann-Whitney, McNemar and Wilcoxon singed rank tests were used. Repeated measures analysis of variance (ANOVA) was adopted, based on scores' logarithmic transformation. Spearman correlations coefficients (rho) were used to explore the association between knowledge and evaluation scores.Results: Results: The knowledge score increased significantly after the lab in total sample and regardless of students' gender and age. The satisfaction was higher regarding the new and important knowledge that students gained and the usefulness of this knowledge in their professional activity.Conclusion: Conclusions: The findings underscore the value of incorporating specialized, hands-on training into nursing curricula to enhance students' competencies in advanced clinical procedures.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 6","pages":"668-678"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143417052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Embryological Significance of Glial cells in the Central Nervous System.

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202406118

Ewa Alicja Ogłodek, Anna Grzesińska, Barbara Paraniak-Gieszczyk, Izabela Woźny-Rasała

引用次数: 0

Unfair criminalization as a threat to epidemic safety.

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202406119

Nataliya Gutorova, Oleksii Soloviov, Yevhen Gnedik

{"title":"Unfair criminalization as a threat to epidemic safety.","authors":"Nataliya Gutorova, Oleksii Soloviov, Yevhen Gnedik","doi":"10.36740/Merkur202406119","DOIUrl":"https://doi.org/10.36740/Merkur202406119","url":null,"abstract":"Objective: Aim: This article aims to raise awareness and stimulate serious discussion of the negative impact of criminal law regulation on the prevention and treatment of infectious diseases, including HIV/AIDS, tuberculosis, and sexually transmitted diseases..Patients and methods: Materials and Methods: The study was conducted in 2024 and based on the empirical and analytical data of the Joint United Nations Programme on HIV/AIDS, the World Health Organization, the legal positions of the ECHR, legal practice and statistics of Ukraine, legal acts of the Ukraine, Germany, Estonia, Lithuania, and Poland. In total, 21 laws, drafts of laws, other documents, and 26 court decisions were analysed. Analytical, comparative, synthetic, systemic, sociological, induction, and deduction research methods were applied.Conclusion: Conclusions: Criminal law should consider the latest medical research results when determining the boundaries of criminal law regulation. It is necessary to proceed from the principle of necessity in a democratic society when deciding on the criminalization of the transmission of HIV, tuberculosis, sexually transmitted diseases, COVID-19, and other infectious diseases. Based on this principle, decriminalization is necessary: a) infection with a disease that does not pose a serious danger; b) placing a person in danger of being infected with an infectious disease if such consequences did not occur and the person did not intend to become infected with such a disease.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 6","pages":"744-748"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143417110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fast resolution of mild midvetricular takotsubo syndrome triggered by blunt chest trauma: case study. 钝性胸部外伤引发的轻度中脑塔克氏综合征的快速缓解：病例研究。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202403115

Waldemar Elikowski, Patryk Szczęśniewski, Natalia Fertała, Magdalena Zawodna-Marszałek, Alina Baszko, Marcin Żytkiewicz

{"title":"Fast resolution of mild midvetricular takotsubo syndrome triggered by blunt chest trauma: case study.","authors":"Waldemar Elikowski, Patryk Szczęśniewski, Natalia Fertała, Magdalena Zawodna-Marszałek, Alina Baszko, Marcin Żytkiewicz","doi":"10.36740/Merkur202403115","DOIUrl":"10.36740/Merkur202403115","url":null,"abstract":"Blunt chest trauma (BCT) may rarely trigger stress-induced takotsubo syndrome (TTS) which requires dif f erential diagnosis with myocardial contusion and BCT-induced myocardial infarction. So far reported cases have been presented as apical ballooning or inverted (reverse) TTS forms but not as a midventricular variant. The authors described a case of a 53-year-old female admitted to Intensive Care Unit after motor vehicle accident with BCT and airbag deployment during car roll over. For some time after the accident, she was trapped in a car with her head bent to the chest. After being pulled out from the car, she had impaired consciousness and therefore was intubated by the rescue team. Trauma computed tomography scan did not reveal any injuries. However, ECG showed ST-segment depression in II, III, aVF, V4-6, and discrete ST-segment elevation in aVR. Troponin I and NTpro-BNP increased to 2062 ng/l and 6413 pg/ml, respectively. Echocardiography revealed mild midventricular dysfunction of the left ventricle with ejection fraction (EF) and global longitudinal strain (GLS) reduced to 45% and -17.6%, respectively. On day two, the patient's general condition improved and stabilized, so she was extubated. Normalization of ECG, EF and GLS (but not regional LS) was observed on day three. She was discharged home on day fi ve. Post-hospital examinations documented that segmental longitudinal strain remained abnormal for up to 4 weeks. The authors conclude that fast ECG and echocardiographic evolution may result in underestimation of the posttraumatic TTS diagnosis, especially if it takes atypical form and its course is mild. Longitudinal strain evaluation can be helpful in cardiac monitoring of trauma patients.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 3","pages":"368-372"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamics of indicators of cadets' daily motor activity in different training years. 不同训练年份学员日常运动指标的动态变化。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202404108

Kostiantyn Prontenko, Valentyn V Bondarenko, Valerii I Plisko, Rostyslav M Radzievskyi, Inesa V Novitska, Oleksiy V Nikitenko, Ostap S Skoruy

{"title":"Dynamics of indicators of cadets' daily motor activity in different training years.","authors":"Kostiantyn Prontenko, Valentyn V Bondarenko, Valerii I Plisko, Rostyslav M Radzievskyi, Inesa V Novitska, Oleksiy V Nikitenko, Ostap S Skoruy","doi":"10.36740/Merkur202404108","DOIUrl":"https://doi.org/10.36740/Merkur202404108","url":null,"abstract":"Objective: Aim: The aim is to investigate the dynamics of indicators of daily motor activity of cadets of higher educational institutions with specific learning environment in different training years.Patients and methods: Materials and Methods: The research involved 226 cadets of the National Academy of Internal Affairs in the first (n = 62), second (n = 56), third (n = 60), and fourth (n = 48) training years. We used the Framingham method which involves the calculation of the motor activity index to determine the daily time spent on cadets' motor activity and their daily energy expenditure.Results: Results: The dynamics of motor activity indicators of cadets in different training years have been studied. The best index were found in the third-year cadets (34.12 ± 0.49 points and 2643.9 ± 36.6 kcal), and the worst - in the first (32.68 ± 0.43 points and 2537 ± 33.9 kcal) and fourth (32.85 ± 0.41 points and 2550.9 ± 31.3 kcal). At the same time, a significant difference between the indicators of motor activity per day was found only in the first- and third-year cadets (p < 0.05). In general, the level of daily motor activity of the first- and fourth-year cadets is assessed as insufficient (inadequate), and of the secondand third-year cadets - as proper.Conclusion: Conclusions: The results obtained indicate the need to increase the daily level of motor activity of cadets by involving them in sporting and mass participation events and extracurricular physical exercises and increasing the intensity of physical training sessions.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 4","pages":"433-438"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features of d-vitamin status in young children in the Kazakh population. 哈萨克斯坦人口中幼儿 d 维生素状况的特点。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202402104

Akmaral Zhumalina, Irina Kim, Balash Tusupkaliev, Mairamkul Zharlykasinova, Botagoz Zhekeyeva

{"title":"Features of d-vitamin status in young children in the Kazakh population.","authors":"Akmaral Zhumalina, Irina Kim, Balash Tusupkaliev, Mairamkul Zharlykasinova, Botagoz Zhekeyeva","doi":"10.36740/Merkur202402104","DOIUrl":"https://doi.org/10.36740/Merkur202402104","url":null,"abstract":"Objective: Aim: The purpose of the article is to form the parameters of vitamin D status in young children in the ethnic group of Kazakh nationality with the factor of highlighting the necessary recommendations for the prevention of hypovitaminosis D.Patients and methods: Materials and Methods: Methods for the study of the highlighted problem are the diagnosis of young children in the parameter of clinical and anamnestic research, which includes the collection of anamnestic data of children of Kazakh nationality within the framework of the identified data based on a questionnaire of parents, an evaluation component in the child's health factor at the level of his initial state, and laboratory analysis to determine 25(OH)D to identify the content of vitamin D using the method of electrochemiluminescent immunoassay.Results: Results: Analysis of vitamin D levels revealed significant differences among age groups. In the 0-28-day group, average vitamin D was 13.35 ng/ml, with 92.8% deficient. In the 1-6-month group, it was 21.47 ng/ml, with 84% deficient. In the over 6-month group, it was 33.58 ng/ml, with 40% sufficient. Formula-fed children had the lowest levels (average 15.21 ng/ml), while breastfed children had insufficiency (average 23.91 ng/ml). Children with vitamin D supplementation averaged 25.9 ng/ml, compared to 19.01 ng/ml without supplementation.Conclusion: Conclusions: The results point to a widespread deficiency of vitamin D and offer practical recommendations for its prevention, such as creating a unified system of timely diagnosis, implementing preventive measures in pregnant women and young children, including a balanced diet enriched with vitamin D, staying outdoors in the bright hours of the day.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 2","pages":"161-170"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gender and age-related features of anxiety and depressive symptoms in patients in the acute phase of COVID-19. COVID-19 急性期患者焦虑和抑郁症状的性别和年龄相关特征。

Polski Merkuriusz Lekarski Pub Date : 2024-01-01 DOI: 10.36740/Merkur202402107

Iryna Mudrenko, Vitalii Mudrenko, Oksana Kolenko, Anastasia Kotkova, Ludmyla Kiptenko

{"title":"Gender and age-related features of anxiety and depressive symptoms in patients in the acute phase of COVID-19.","authors":"Iryna Mudrenko, Vitalii Mudrenko, Oksana Kolenko, Anastasia Kotkova, Ludmyla Kiptenko","doi":"10.36740/Merkur202402107","DOIUrl":"https://doi.org/10.36740/Merkur202402107","url":null,"abstract":"Objective: Aim: To investigate the gender and age characteristics of psychopathological symptoms in patients in the acute phase of respiratory infection SARS-CoV-2.Patients and methods: Materials and Methods: A total of 66 patients aged 8 to 92 years, sick with COVID-19 during inpatient treatment with lung damage from 30 to 70%, confirmed radiologically, in the period up to 20 days from the onset of the disease, were examined. To assess the mental status of patients with COVID-19, we used a clinical, clinical-psychopathological, psychometric method, which included the following questionnaires as part of psychiatric screening for studying psychopathological symptoms upon admission to the hospital. The Patient Health Questionnaire - PHQ-9, The Generalised Anxiety Disorder - GAD-7, Hamilton Test were used. The research data collection period is from 2020 to 2022.Results: Results: Acute respiratory infection СОVID-19 affects the psycho-emotional state. During inpatient treatment, 60.6% of patients have symptoms of depression, 66.1% have anxiety symptoms. Most women with COVID-19 are characterized by moderate depression according to PHQ-9, mild anxiety according to GAD-7, and moderate anxiety according to Hamilton. Mild depression characterizes most men according to PHQ-9, absence of anxiety according to GAD-7, and mild anxiety according to Hamilton. Anxiety symptoms were less pronounced among men with COVID-19, with insomnia and respiratory symptoms being the most significant. Among women, anxiety (p≤0.001), tension, depression (p≤0.001), somatic muscle (p≤0.001) and respiratory symptoms (p≤0.001) predominate in the structure of anxiety during the active phase of COVID-19.Conclusion: Conclusions: The data obtained will be useful in the development of psychoprophylactic measures in patients with COVID-19.","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 2","pages":"189-196"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0