Assessment of parathyroid hormone, vitamin D3, calcium, phosphate, and RFT in patients with chronic renal failure: A three-year follow-up study.

Q3 Medicine

Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI:10.36740/Merkur202501106

Hamid K Al-Tameemi, Noor Ibrahim, Dina A A Abdullah, Noor Nayyef Oddah

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引用次数: 0

Abstract

Objective: Aim: This study aimed to evaluate the serum levels of key biomarkers, including parathyroid hormone (PTH), vitamin D3, calcium, phosphate, and renal function tests (RFTS), in patients with chronic renal failure over three years..

Patients and methods: Materials and Methods: A cohort of 83 patients with chronic renal failure and 70 healthy controls were followed, with data collected at one, two, and three years.

Results: Results: Significant differences were observed in the levels of creatinine, urea, phosphate, calcium, vitamin D, and parathyroid hormone between patients and controls. the study found a progressive increase in phosphate and parathyroid hormone levels, alongside a decrease in calcium and vitamin D levels in patients over time. strong correlations were observed between these biomarkers, highlighting the complex interplay between mineral metabolism and renal function in chronic renal failure.

Conclusion: Conclusions: These findings confirm the need for integrated management strategies to address these biochemical disturbances and improve the life quality of patients with chronic renal failure.

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研究目的目的：本研究旨在评估慢性肾功能衰竭患者三年内血清中主要生物标志物的水平，包括甲状旁腺激素（PTH）、维生素D3、钙、磷酸盐和肾功能检测（RFTS）：材料与方法：对 83 名慢性肾功能衰竭患者和 70 名健康对照者进行了队列随访，并收集了 1 年、2 年和 3 年的数据：结果研究发现，随着时间的推移，患者体内的磷酸盐和甲状旁腺激素水平逐渐升高，而钙和维生素 D 水平则逐渐降低。这些生物标志物之间存在很强的相关性，凸显了慢性肾衰竭患者体内矿物质代谢和肾功能之间复杂的相互作用：结论这些研究结果证实，需要采取综合管理策略来解决这些生化紊乱问题，并改善慢性肾衰竭患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polski Merkuriusz Lekarski Medicine-Medicine (all)

CiteScore

1.90

自引率

0.00%

发文量