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A little praise goes a long way. 一点表扬会大有帮助。

Practitioner Pub Date : 2016-06-01

David Haslam

引用次数: 0

Erectile dysfunction heralds onset of cardiovascular disease. 勃起功能障碍预示心血管疾病的发生。

Practitioner Pub Date : 2016-06-01

Joyee Basu, Sanjay Sharma

{"title":"Erectile dysfunction heralds onset of cardiovascular disease.","authors":"Joyee Basu, Sanjay Sharma","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Erectile dysfunction (ED) was once assumed to be a psychological condition but has now been shown to share risk factors with cardiovascular disease including age, diabetes mellitus, smoking, hypertension and hypercholesterolaemia, suggesting an underlying vascular pathology. Evidence reveals that there is a potential link between ED and subsequent development of coronary artery disease. ED itself may also increase cardiovascular risk. The relative risk of developing coronary artery disease within ten years, in patients with moderate to severe ED, has been calculated as 14% in men aged 30-39 years and may be as high as 27% in those aged 60-69. The association appears greater when younger men presenting with ED are considered. The severity of ED has also been linked with the severity of coronary artery disease The proposed pathological mechanisms are based on a theory of endothelial dysfunction which eventually leads to atherosclerosis. This occurs first in more vulnerable narrow diameter vessels such as the cavernosal arteries. The artery size hypothesis may explain why ED occurs before manifestation of coronary artery disease. There is likely to be a delay between presentation with ED and clinical presentation with coronary artery disease. In one study, ED was found to present 39 months prior to coronary symptoms. This provides GPs with a valuable window of opportunity for risk assessment, subsequent primary prevention and early referral to a cardiologist.</p>","PeriodicalId":39516,"journal":{"name":"Practitioner","volume":"260 1794","pages":"21-3, 3"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34329062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BLOOD-LETTING IN 1916. 1916年的流血事件。

Practitioner Pub Date : 2016-06-01

Leonard Williams

引用次数: 0

NEURASTHENIA IN WAR. 战争中的神经衰弱。

Practitioner Pub Date : 2016-05-01

Frederick C Forster

引用次数: 0

Antidepressants and cardiovascular risk. 抗抑郁药和心血管风险。

Practitioner Pub Date : 2016-05-01

Phillip Bland

引用次数: 0

Careful assessment the key to diagnosing adolescent heel pain. 仔细评估是诊断青少年足跟痛的关键。

Practitioner Pub Date : 2016-05-01

Martin J Davison, S Kenneth David-West, Roderick Duncan

{"title":"Careful assessment the key to diagnosing adolescent heel pain.","authors":"Martin J Davison, S Kenneth David-West, Roderick Duncan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The most common cause of adolescent heel pain is calcaneal apophysitis also known as Sever's disease. The condition may occur in adolescent athletes, particularly those involved in running or jumping activities, during the pubertal growth spurt. The mean age of presentation in Sever's disease is ten, (range 7-15). It presents with posterior heel pain that is worse with activity and relieved by rest in most cases. Sever's disease, Osgood Schlatter's disease (tibial tuberosity) and Sinding-Larsen Johansson syndrome (distal patella) are all overuse syndromes brought about by repetitive submaximal loading and microtrauma. They are, however, entirely self-limiting and resolve at skeletal maturity or earlier. Careful assessment is required to differentiate them from other rare pathologies. Achilles tendinitis is rare under the age of 14. As in Sever's disease, it may occur in jumping athletes, those who suddenly increase their sporting activities and in individuals with relative gastrosoleus tightness. It may also occur in those with inflammatory arthropathies and merit rheumatological investigation if there are other suggestive signs or symptoms. Benign and malignant tumours of the adolescent calcaneus are extremely rare In a unilateral case, atypical features such as night pain or absence of a precipitating activity should raise the index of suspicion. There may be localised swelling and bony expansion.</p>","PeriodicalId":39516,"journal":{"name":"Practitioner","volume":"260 1793","pages":"30-2, 3"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34641665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing patients with hidradenitis suppurativa. 化脓性汗腺炎的处理。

Practitioner Pub Date : 2016-05-01

Stephanie L Ball, Michael J Tidman

引用次数: 0

Diagnosing young onset dementia can be challenging. 诊断年轻发病的痴呆症可能具有挑战性。

Practitioner Pub Date : 2016-05-01

Samrah Ahmed, Ian Baker, Christopher R Butler

{"title":"Diagnosing young onset dementia can be challenging.","authors":"Samrah Ahmed, Ian Baker, Christopher R Butler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although the risk of developing dementia increases with age, onset can be as early as the third or fourth decade of life. Genetic influences play a more important role in younger than in older people with dementia, so young onset dementia may cluster in families. Diagnosing young onset dementia is challenging. The range of possible presenting features is broad, encompassing behavioural, cognitive, psychiatric and neurological domains, and symptoms are often subtle initially. Frequently the complaints are misattributed to stress or depression, and the patient is falsely reassured that they are too young to have dementia. The most common causes of young onset dementia are early onset forms of adult neurodegenerative conditions and alcohol. Vascular dementia is the second most common cause of young onset dementia after Alzheimer's disease. Conventional vascular risk factors may be absent and diagnosis relies on imaging evidence of cerebrovascular disease. Obtaining a detailed history remains the most important part of the workup and usually requires corroboration by a third party. Undertaking a basic neurological examination is also important. Those with suspected young onset dementia should be referred to a neurology-led cognitive disorders clinic where available as the differenti diagnosis is considerably broader tha in older adults and requires specialist investigation.</p>","PeriodicalId":39516,"journal":{"name":"Practitioner","volume":"260 1793","pages":"11-7, 2"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34641662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Be vigilant for post-traumatic stress reactions. 警惕创伤后应激反应。

Practitioner Pub Date : 2016-05-01

Alastair M Hull, Stephen A Curran

引用次数: 0

A lesson from a patient. 一个病人的教训。

Practitioner Pub Date : 2016-05-01

David Haslam

引用次数: 0

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