诊断年轻发病的痴呆症可能具有挑战性。

Practitioner Pub Date : 2016-05-01
Samrah Ahmed, Ian Baker, Christopher R Butler
{"title":"诊断年轻发病的痴呆症可能具有挑战性。","authors":"Samrah Ahmed,&nbsp;Ian Baker,&nbsp;Christopher R Butler","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Although the risk of developing dementia increases with age, onset can be as early as the third or fourth decade of life. Genetic influences play a more important role in younger than in older people with dementia, so young onset dementia may cluster in families. Diagnosing young onset dementia is challenging. The range of possible presenting features is broad, encompassing behavioural, cognitive, psychiatric and neurological domains, and symptoms are often subtle initially. Frequently the complaints are misattributed to stress or depression, and the patient is falsely reassured that they are too young to have dementia. The most common causes of young onset dementia are early onset forms of adult neurodegenerative conditions and alcohol. Vascular dementia is the second most common cause of young onset dementia after Alzheimer's disease. Conventional vascular risk factors may be absent and diagnosis relies on imaging evidence of cerebrovascular disease. Obtaining a detailed history remains the most important part of the workup and usually requires corroboration by a third party. Undertaking a basic neurological examination is also important. Those with suspected young onset dementia should be referred to a neurology-led cognitive disorders clinic where available as the differenti diagnosis is considerably broader tha in older adults and requires specialist investigation.</p>","PeriodicalId":39516,"journal":{"name":"Practitioner","volume":"260 1793","pages":"11-7, 2"},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnosing young onset dementia can be challenging.\",\"authors\":\"Samrah Ahmed,&nbsp;Ian Baker,&nbsp;Christopher R Butler\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Although the risk of developing dementia increases with age, onset can be as early as the third or fourth decade of life. Genetic influences play a more important role in younger than in older people with dementia, so young onset dementia may cluster in families. Diagnosing young onset dementia is challenging. The range of possible presenting features is broad, encompassing behavioural, cognitive, psychiatric and neurological domains, and symptoms are often subtle initially. Frequently the complaints are misattributed to stress or depression, and the patient is falsely reassured that they are too young to have dementia. The most common causes of young onset dementia are early onset forms of adult neurodegenerative conditions and alcohol. Vascular dementia is the second most common cause of young onset dementia after Alzheimer's disease. Conventional vascular risk factors may be absent and diagnosis relies on imaging evidence of cerebrovascular disease. Obtaining a detailed history remains the most important part of the workup and usually requires corroboration by a third party. Undertaking a basic neurological examination is also important. Those with suspected young onset dementia should be referred to a neurology-led cognitive disorders clinic where available as the differenti diagnosis is considerably broader tha in older adults and requires specialist investigation.</p>\",\"PeriodicalId\":39516,\"journal\":{\"name\":\"Practitioner\",\"volume\":\"260 1793\",\"pages\":\"11-7, 2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Practitioner\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Practitioner","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

虽然患痴呆症的风险随着年龄的增长而增加,但发病可能早在生命的第三或第四个十年。遗传影响在年轻人中比在老年人中发挥更重要的作用,因此年轻发病的痴呆症可能集中在家庭中。诊断年轻发病的痴呆症是一项挑战。可能的表现特征范围很广,包括行为、认知、精神和神经领域,症状最初往往很微妙。这些抱怨经常被错误地归咎于压力或抑郁,病人被错误地安慰说,他们太年轻了,不会患痴呆症。早发性痴呆的最常见原因是成人神经退行性疾病的早期发作形式和酒精。血管性痴呆是继阿尔茨海默病之后导致年轻痴呆的第二大常见原因。传统的血管危险因素可能不存在,诊断依赖于脑血管疾病的影像学证据。获得详细的病史仍然是检查中最重要的部分,通常需要第三方的证实。进行基本的神经检查也很重要。那些疑似年轻发病的痴呆症患者应转诊到神经学主导的认知障碍诊所,因为不同的诊断比老年人广泛得多,需要专家调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosing young onset dementia can be challenging.

Although the risk of developing dementia increases with age, onset can be as early as the third or fourth decade of life. Genetic influences play a more important role in younger than in older people with dementia, so young onset dementia may cluster in families. Diagnosing young onset dementia is challenging. The range of possible presenting features is broad, encompassing behavioural, cognitive, psychiatric and neurological domains, and symptoms are often subtle initially. Frequently the complaints are misattributed to stress or depression, and the patient is falsely reassured that they are too young to have dementia. The most common causes of young onset dementia are early onset forms of adult neurodegenerative conditions and alcohol. Vascular dementia is the second most common cause of young onset dementia after Alzheimer's disease. Conventional vascular risk factors may be absent and diagnosis relies on imaging evidence of cerebrovascular disease. Obtaining a detailed history remains the most important part of the workup and usually requires corroboration by a third party. Undertaking a basic neurological examination is also important. Those with suspected young onset dementia should be referred to a neurology-led cognitive disorders clinic where available as the differenti diagnosis is considerably broader tha in older adults and requires specialist investigation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Practitioner
Practitioner Medicine-Family Practice
自引率
0.00%
发文量
1
期刊介绍: The term "practitioner" of course has general application. It is used in a wide variety of professional contexts and industry and service sectors. The Practioner.Com portal is intended to support professionals in a growing number of these. Across a range of sub-sites, we offer a raft of useful information and data on the core topic(s) covered. These range from Legal Practioner (legal profession) through ITIL Practitioner (IT Infrastructure Library), Information Security Practitioner, Insolvency Practitioner (IP), General Practitioner and beyond.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信