Hipertension y Riesgo Vascular最新文献

{"title":"Assessing levels of uric acid and other cardiovascular markers in prehypertensive and hypertensive adults","authors":"","doi":"10.1016/j.hipert.2024.04.003","DOIUrl":"10.1016/j.hipert.2024.04.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Although some studies have reported the association between uric acid (UA) and hypertension, evidence on prehypertension is still lacking. Therefore, the objective of this study was to determine the levels of UA and other cardiovascular markers among prehypertensive and hypertensive patients and assess their risk for developing arterial hypertension.</p></div><div><h3>Methods</h3><p>157 individuals were recruited: 67 normotensive, 23 pre-hypertensive and 67 hypertensive. Blood samples were collected to measure biochemical parameters and anthropometric measurements and blood pressure were evaluated. We calculated the product of lipid accumulation and the visceral adiposity index to assess cardiovascular risk.</p></div><div><h3>Results</h3><p>Our data showed an increase in UA levels in normotensives (4.9<!--> <!-->±<!--> <!-->1.3<!--> <!-->mg/dL), prehypertensives (5.2<!--> <!-->±<!--> <!-->1.3<!--> <!-->mg/dL) and hypertensives (5.9<!--> <!-->±<!--> <!-->1.6<!--> <!-->mg/dL) (<em>p</em> <!-->=<!--> <!-->0.004). We found a higher frequency of hyperuricemia in the hypertensive group (34.3%) than in the normotensive group (13.4%, <em>p</em> <!-->&lt;<!--> <!-->0.05). Hypertensive volunteers had lower levels of HDL-C (<em>p</em> <!-->=<!--> <!-->0.004 and <em>p</em> <!-->=<!--> <!-->0.003) and higher body mass indexes (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.007), glucose (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.033), triglycerides (<em>p</em> <!-->=<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.005), visceral adiposity index (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.002) and lipid accumulation product (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.007) than normotensive and prehypertensive participants. We also observed that individuals with UA<!--> <!-->≥<!--> <!-->6.2<!--> <!-->mg/dL had an increased risk of hypertension of 4.77 (<em>p</em> <!-->=<!--> <!-->0.003) compared to individuals with levels<!--> <!-->≤<!--> <!-->4.3<!--> <!-->mg/dL.</p></div><div><h3>Conclusion</h3><p>Our results showed that UA is associated with increased blood pressure and unfavorable changes in anthropometric and biochemical parameters, which represent risk factors for hypertension and cardiovascular diseases.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 154-161"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic biomarkers and cardiovascular risk stratification in hypertension","authors":"D. Piskorz,&nbsp;L. Keller,&nbsp;L. Citta,&nbsp;G. Tissera,&nbsp;L. Mata,&nbsp;L. Bongarzoni","doi":"10.1016/j.hipert.2024.06.003","DOIUrl":"10.1016/j.hipert.2024.06.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Cardiovascular risk calculators (CRC) are not locally validated and calibrated. Surrogate biomarkers of insulin resistance had identified subjects at higher risk of type 2 diabetes and cardiovascular disease.</p></div><div><h3>Aim</h3><p>Establish the frequency of surrogate biomarkers of insulin resistance and their correlation with CRC in primary prevention non-diabetic hypertensive subjects.</p></div><div><h3>Methods</h3><p>This is an observational registry with a prospective consecutive outpatient's sample. The TyG index (TyGi) was calculated as logarithm (Ln) of (fasting triglycerides [mg/dl]<!--> <!-->×<!--> <!-->fasting plasma glucose [mg/dl]/2). Patients were stratified according to quartiles of TyGi. Pearson correlation coefficient between TyGi and other relevant variables was evaluated.</p></div><div><h3>Results</h3><p>Four hundred six patients were included with a mean age 55.9<!--> <!-->±<!--> <!-->13 years, 231 p (56.9%) males. The mean TyGi was 8.667<!--> <!-->±<!--> <!-->0.53. Patients in the highest quartiles of TyGi had significantly higher median difference between expected and actual ASCVD risk (<em>p</em> <!-->=<!--> <!-->0.02), higher frequency of AHA/ACC Pooled Cohort Equation &gt;7.5% (<em>p</em> <!-->&lt;<!--> <!-->0.005), and higher levels of metabolic biomarkers such as median triglyceridemia/HDL cholesterol ratio (TG/HDL) (<em>p</em> <!-->&lt;<!--> <!-->0.0005), glycaemia and A1C (<em>p</em> <!-->&lt;<!--> <!-->0.001 and <em>p</em> <!-->=<!--> <!-->0.02, respectively). The correlation between TyGi and TG/HDL was highly significant (<em>r</em> <!-->=<!--> <!-->0.7076; <em>r</em>² <!-->=<!--> <!-->0.5007; <em>p</em> <!-->&lt;<!--> <!-->0.0001), and intermediate with non-HDL cholesterol (<em>r</em> <!-->=<!--> <!-->0.4553, <em>r</em>² <!-->=<!--> <!-->0.2073; <em>p</em> <!-->&lt;<!--> <!-->0.0001).</p></div><div><h3>Conclusions</h3><p>Non-diabetic hypertensive patients with high TyGi, a surrogate biomarker of insulin resistance, had a higher 10-year cardiovascular risk by AHA/ACC Pooled Cohort Equation. TyGi is statistically and significantly correlated with other biomarkers of insulin resistance. TyGi could be a reliable biomarker in clinical practice to stratify cardiovascular risk.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 162-169"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/j.hipert.2024.05.002","DOIUrl":"10.1016/j.hipert.2024.05.002","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 205-206"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141950435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of blood pressure monitoring in the acute phase of stroke. An update","authors":"","doi":"10.1016/j.hipert.2024.01.002","DOIUrl":"10.1016/j.hipert.2024.01.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The evaluation of blood pressure (BP) is essential in the acute phase of stroke. Although ambulatory blood pressure monitoring (ABPM) is a validated method for BP control, there are few studies assessing the usefulness of ABPM in the acute phase of stroke.</p></div><div><h3>Development</h3><p>A systematic review was carried out according to the PRISMA criteria in the PubMed/Medline and Scopus databases. Those articles that analysed the use of ABPM in the first days after suffering a stroke from 1992 to 2022 were selected. Those articles focused on the post-acute or sequelae phase of the stroke, with a sample size of less than 20 and those where the primary objective was different from the defined one. A total of 28 articles were included.</p></div><div><h3>Conclusions</h3><p>The use of ABPM in patients with recent stroke demonstrates that the normal circadian profile of BP is altered in more than two-thirds of patients and that this will be fundamentally conditioned by the haemodynamic changes that occur on autoregulation of cerebral blood flow, the type of stroke or the response to treatment. Furthermore, these changes in BP have prognostic implications and are correlated with functional status, stroke recurrence and mortality, among others. However, although they continue to be a growing area of research, new studies are needed to clarify the real role of this technique in patients with acute stroke.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 179-185"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HT and uric acid, uric acid and HT: Is hyperuricemia a new vascular risk factor to consider?","authors":"Mencia Benitez Camps","doi":"10.1016/j.hipert.2024.06.001","DOIUrl":"10.1016/j.hipert.2024.06.001","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 143-144"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"10.1016/j.hipert.2024.05.001","DOIUrl":"10.1016/j.hipert.2024.05.001","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 3","pages":"Pages 203-204"},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141950434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihipertensivos, presión positiva continua en la vía aérea y apnea obstructiva del sueño","authors":"","doi":"10.1016/j.hipert.2024.02.005","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.02.005","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 2","pages":"Pages 139-140"},"PeriodicalIF":0.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140540629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is proteinuria an important fact concerning the nephroprotective effect of renin-angiotensin system inhibitors?","authors":"J.M. Galceran","doi":"10.1016/j.hipert.2024.02.007","DOIUrl":"10.1016/j.hipert.2024.02.007","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 2","pages":"Pages 75-77"},"PeriodicalIF":0.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergencia hipertensiva como debut de síndrome de Cushing paraneoplásico","authors":"E. Rubio González,&nbsp;M. de Valdenebro Recio,&nbsp;M.I. Galán Fernández","doi":"10.1016/j.hipert.2023.10.003","DOIUrl":"10.1016/j.hipert.2023.10.003","url":null,"abstract":"<div><p>We present the case of a patient with a history of renal-vascular hypertension treated with stent one year previously, who attended the emergency room due to hypertensive emergency and dyspnea. Once the first suspicion of renal artery restenosis was ruled out with CT angiography, the study was completed, confirming the diagnosis of lung cancer through imaging and pathological anatomy. In the hormonal study, elevation of ACTH, hypercortisolism and analytical data of hyperaldosteronism were detected. With the final diagnosis of Cushing's syndrome secondary to ectopic production of ACTH, medical treatment was started, without being able to receive anything else due to the death of the patient after a few days.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 2","pages":"Pages 135-138"},"PeriodicalIF":0.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title Page","authors":"","doi":"10.1016/S1889-1837(24)00073-4","DOIUrl":"https://doi.org/10.1016/S1889-1837(24)00073-4","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"41 ","pages":"Page i"},"PeriodicalIF":0.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140880254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}