Topics in Magnetic Resonance Imaging最新文献

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Magnetic Resonance Imaging of Prostate Adenocarcinoma: Detection and Staging. 前列腺癌的磁共振成像:检测和分期。
Topics in Magnetic Resonance Imaging Pub Date : 2020-02-01 DOI: 10.1097/RMR.0000000000000226
Ryan D Ward, Andrei S Purysko
{"title":"Magnetic Resonance Imaging of Prostate Adenocarcinoma: Detection and Staging.","authors":"Ryan D Ward,&nbsp;Andrei S Purysko","doi":"10.1097/RMR.0000000000000226","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000226","url":null,"abstract":"<p><p>Prostate cancer (PCa) is common among men worldwide and is a major cause of morbidity and mortality. The detection of PCa has historically followed a stepwise process of prostate-specific antigen screening followed with systematic transrectal ultrasound-guided biopsy. Magnetic resonance imaging (MRI), utilizing a set of sequences to assess morphology and function, has gained clinical acceptance to detect, characterize, and stage PCa. The Prostate Imaging - Reporting and Data System has helped facilitate the standardization of reporting across institutions and increased adoption of this method. In this review, we will (1) discuss the strengths and weaknesses of conventional diagnostic methods; (2) describe the clinical utility of prostate MRI, specifically addressing its uses in the detection and staging of PCa; and (3) list important technical parameters required for state-of-the-art prostate MRI.</p>","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"29 1","pages":"17-30"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/RMR.0000000000000226","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37606180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Prostate Benign Diseases. 前列腺良性疾病。
Topics in Magnetic Resonance Imaging Pub Date : 2020-02-01 DOI: 10.1097/RMR.0000000000000227
Cassia T S Guimaraes, Luisa J Sauer, Ricardo F T Romano, Eduardo O Pacheco, Leonardo K Bittencourt
{"title":"Prostate Benign Diseases.","authors":"Cassia T S Guimaraes,&nbsp;Luisa J Sauer,&nbsp;Ricardo F T Romano,&nbsp;Eduardo O Pacheco,&nbsp;Leonardo K Bittencourt","doi":"10.1097/RMR.0000000000000227","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000227","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) has been increasingly used in the detection, localization, and staging of prostate cancer. Because of its excellent soft tissue contrast and multiplane imaging, it can be also very useful in the evaluation of benign prostate diseases. Prostatic benign disorders have a high prevalence, vastly represented by benign prostatic hyperplasia and prostatitis. On the contrary, benign prostatic neoplasms are extremely rare, represented by multilocular cystadenoma, leiomyomas, hemangioma, and granular cell tumor, although these uncommon tumors have been most encountered due to widespread use of MRI. Congenital prostatic anomalies are associated with defects in the development of the prostate embryology, including hypoplasia, ectopia, and vascular malformations, abnormalities rarely seen on cross-sectional imaging. Prostatic cysts are the most common development abnormalities and occasionally are related to clinical symptoms, mainly due to infection and hemorrhage. As with prostate cancer, multiparametric MRI is a reliable tool for the diagnosis and management of benign prostatic diseases as well, providing additional information such morphological changes of the prostate, more accurate prostatic measurements, and functional characteristics of nonmalignant prostatic lesions. In this review, we discuss MRI findings of these benign prostatic diseases.</p>","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"29 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/RMR.0000000000000227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37606179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Functional Connectivity in Neurodegenerative Disorders: Alzheimer's Disease and Frontotemporal Dementia. 神经退行性疾病的功能连通性:阿尔茨海默病和额颞叶痴呆。
Topics in Magnetic Resonance Imaging Pub Date : 2019-12-01 DOI: 10.1097/RMR.0000000000000223
R. Jalilianhasanpour, E. Beheshtian, Ghazi Sherbaf, S. Sahraian, H. Sair
{"title":"Functional Connectivity in Neurodegenerative Disorders: Alzheimer's Disease and Frontotemporal Dementia.","authors":"R. Jalilianhasanpour, E. Beheshtian, Ghazi Sherbaf, S. Sahraian, H. Sair","doi":"10.1097/RMR.0000000000000223","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000223","url":null,"abstract":"Neurodegenerative disorders are a growing cause of morbidity and mortality worldwide. Onset is typically insidious and clinical symptoms of behavioral change, memory loss, or cognitive dysfunction may not be evident early in the disease process. Efforts have been made to discover biomarkers that allow for earlier diagnosis of neurodegenerative disorders, to initiate treatment that may slow the course of clinical deterioration. Neuronal dysfunction occurs earlier than clinical symptoms manifest. Thus, assessment of neuronal function using functional brain imaging has been examined as a potential biomarker. While most early studies used task-functional magnetic resonance imaging (fMRI), with the more recent technique of resting-state fMRI, \"intrinsic\" relationships between brain regions or brain networks have been studied in greater detail in neurodegenerative disorders. In Alzheimer's disease, the most common neurodegenerative disorder, and frontotemporal dementia, another of the common dementias, specific brain networks may be particularly susceptible to dysfunction. In this review, we highlight the major findings of functional connectivity assessed by resting state fMRI in Alzheimer's disease and frontotemporal dementia.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83640566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Clinical Use of Integrated Positron Emission Tomography-Magnetic Resonance Imaging for Dementia Patients. 正电子发射断层扫描-磁共振成像在痴呆患者中的临床应用。
Topics in Magnetic Resonance Imaging Pub Date : 2019-12-01 DOI: 10.1097/RMR.0000000000000225
T. Shepherd, Gopi K. Nayak
{"title":"Clinical Use of Integrated Positron Emission Tomography-Magnetic Resonance Imaging for Dementia Patients.","authors":"T. Shepherd, Gopi K. Nayak","doi":"10.1097/RMR.0000000000000225","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000225","url":null,"abstract":"Combining magnetic resonance imaging (MRI) with 2-deoxy-2-F-fluoro-D-glucose positron emission tomography (FDG-PET) data improve the imaging accuracy for detection of Alzheimer disease and related dementias. Integrated FDG-PET-MRI is a recent technical innovation that allows both imaging modalities to be obtained simultaneously from individual patients with cognitive impairment. This report describes the practical benefits and challenges of using integrated FDG-PET-MRI to support the clinical diagnosis of various dementias. Over the past 7 years, we have performed integrated FDG-PET-MRI on >1500 patients with possible cognitive impairment or dementia. The FDG-PET and MRI protocols are the same as current conventions, but are obtained simultaneously over 25 minutes. An additional Dixon MRI sequence with superimposed bone atlas is used to calculate PET attenuation correction. A single radiologist interprets all imaging data and generates 1 report. The most common positive finding is concordant temporoparietal volume loss and FDG hypometabolism that suggests increased risk for underlying Alzheimer disease. Lobar-specific atrophy and FDG hypometabolism patterns that may be subtle, asymmetric, and focal also are more easily recognized using combined FDG-PET and MRI, thereby improving detection of other neurodegeneration conditions such as primary progressive aphasias and frontotemporal degeneration. Integrated PET-MRI has many practical benefits to individual patients, referrers, and interpreting radiologists. The integrated PET-MRI system requires several modifications to standard imaging center workflows, and requires training individual radiologists to interpret both modalities in conjunction. Reading MRI and FDG-PET together increases imaging diagnostic yield for individual patients; however, both modalities have limitations in specificity.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90393434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The Radiogenomics of Late-onset Alzheimer Disease. 迟发性阿尔茨海默病的放射基因组学。
Topics in Magnetic Resonance Imaging Pub Date : 2019-12-01 DOI: 10.1097/RMR.0000000000000222
L. Bonham, Daniel W. Sirkis, C. Hess, L. Sugrue, J. Yokoyama
{"title":"The Radiogenomics of Late-onset Alzheimer Disease.","authors":"L. Bonham, Daniel W. Sirkis, C. Hess, L. Sugrue, J. Yokoyama","doi":"10.1097/RMR.0000000000000222","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000222","url":null,"abstract":"Radiogenomics, defined as the integrated analysis of radiologic imaging and genetic data, is a well-established tool shown to augment neuroimaging in the clinical diagnosis, prognostication, and scientific study of late-onset Alzheimer disease (LOAD). Early work using candidate single nucleotide polymorphisms (SNPs) identified genetic variation in APOE, BIN1, CLU, and CR1 as key modifiers of brain structure and function using magnetic resonance imaging (MRI). More recently, polygenic risk scores used in conjunction with MRI and positron emission tomography have shown great promise as a risk-stratification tool for clinical trials and care-management decisions. In addition, recent work using multimodal MRI and positron emission tomography as proxies of LOAD progression has identified novel risk variants that are enhancing our understanding of LOAD pathophysiology and progression. Herein, we highlight key studies and trends in the radiogenomics of LOAD over the past two decades and their implications for clinical practice and scientific research.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84108534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Overview of MR Imaging Volumetric Quantification in Neurocognitive Disorders. 神经认知障碍磁共振成像体积量化综述。
Topics in Magnetic Resonance Imaging Pub Date : 2019-12-01 DOI: 10.1097/RMR.0000000000000224
C. Raji, M. Ly, T. Benzinger
{"title":"Overview of MR Imaging Volumetric Quantification in Neurocognitive Disorders.","authors":"C. Raji, M. Ly, T. Benzinger","doi":"10.1097/RMR.0000000000000224","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000224","url":null,"abstract":"This review article provides a general overview on the various methodologies for quantifying brain structure on magnetic resonance images of the human brain. This overview is followed by examples of applications in Alzheimer dementia and mild cognitive impairment. Other examples will include traumatic brain injury and other neurodegenerative dementias. Finally, an overview of general principles for protocol acquisition of magnetic resonance imaging for volumetric quantification will be discussed along with the current choices of FDA cleared algorithms for use in clinical practice.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79046746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Fetal Echoplanar Imaging: Promises and Challenges. 胎儿超声平面成像:前景与挑战。
Topics in Magnetic Resonance Imaging Pub Date : 2019-10-01 DOI: 10.1097/RMR.0000000000000219
Onur Afacan, Judy A Estroff, Edward Yang, Carol E Barnewolt, Susan A Connolly, Richard B Parad, Robert V Mulkern, Simon K Warfield, Ali Gholipour
{"title":"Fetal Echoplanar Imaging: Promises and Challenges.","authors":"Onur Afacan, Judy A Estroff, Edward Yang, Carol E Barnewolt, Susan A Connolly, Richard B Parad, Robert V Mulkern, Simon K Warfield, Ali Gholipour","doi":"10.1097/RMR.0000000000000219","DOIUrl":"10.1097/RMR.0000000000000219","url":null,"abstract":"<p><p>Fetal magnetic resonance imaging (MRI) has been gaining increasing interest in both clinical radiology and research. Echoplanar imaging (EPI) offers a unique potential, as it can be used to acquire images very fast. It can be used to freeze motion, or to get multiple images with various contrast mechanisms that allow studying the microstructure and function of the fetal brain and body organs. In this article, we discuss the current clinical and research applications of fetal EPI. This includes T2*-weighted imaging to better identify blood products and vessels, using diffusion-weighted MRI to investigate connections of the developing brain and using functional MRI (fMRI) to identify the functional networks of the developing brain. EPI can also be used as an alternative structural sequence when banding or standing wave artifacts adversely affect the mainstream sequences used routinely in structural fetal MRI. We also discuss the challenges with EPI acquisitions, and potential solutions. As EPI acquisitions are inherently sensitive to susceptibility artifacts, geometric distortions limit the use of high-resolution EPI acquisitions. Also, interslice motion and transmit and receive field inhomogeneities may create significant artifacts in fetal EPI. We conclude by discussing promising research directions to overcome these challenges to improve the use of EPI in clinical and research applications.</p>","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"28 5","pages":"245-254"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788763/pdf/nihms-1534369.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41215379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental Pathoconnectomics and Advanced Fetal MRI. 发育病理连接组学和晚期胎儿MRI。
Topics in Magnetic Resonance Imaging Pub Date : 2019-10-01 DOI: 10.1097/RMR.0000000000000220
A. Jakab
{"title":"Developmental Pathoconnectomics and Advanced Fetal MRI.","authors":"A. Jakab","doi":"10.1097/RMR.0000000000000220","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000220","url":null,"abstract":"Developmental pathoconnectomics is an emerging field that aims to unravel the events leading to and outcome from disrupted brain connectivity development. Advanced magnetic resonance imaging (MRI) technology enables the portrayal of human brain connectivity before birth and has the potential to offer novel insights into normal and pathological human brain development. This review gives an overview of the currently used MRI techniques for connectomic imaging, with a particular focus on recent studies that have successfully translated these to the in utero or postmortem fetal setting. Possible mechanisms of how pathologies, maternal, or environmental factors may interfere with the emergence of the connectome are considered. The review highlights the importance of advanced image post processing and the need for reproducibility studies for connectomic imaging. Further work and novel data-sharing efforts would be required to validate or disprove recent observations from in utero connectomic studies, which are typically limited by low case numbers and high data drop out. Novel knowledge with regard to the ontogenesis, architecture, and temporal dynamics of the human brain connectome would lead to the more precise understanding of the etiological background of neurodevelopmental and mental disorders. To achieve this goal, this review considers the growing evidence from advanced fetal connectomic imaging for the increased vulnerability of the human brain during late gestation for pathologies that might lead to impaired connectome development and subsequently interfere with the development of neural substrates serving higher cognition.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79105041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Challenges and Opportunities in Connectome Construction and Quantification in the Developing Human Fetal Brain. 发育中的人类胎儿大脑连接体构建与量化的挑战与机遇。
Topics in Magnetic Resonance Imaging Pub Date : 2019-10-01 DOI: 10.1097/RMR.0000000000000212
D. Hunt, M. Dighe, Chris Gatenby, C. Studholme
{"title":"Challenges and Opportunities in Connectome Construction and Quantification in the Developing Human Fetal Brain.","authors":"D. Hunt, M. Dighe, Chris Gatenby, C. Studholme","doi":"10.1097/RMR.0000000000000212","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000212","url":null,"abstract":"The white matter structure of the human brain undergoes critical developmental milestones in utero, which we can observe noninvasively using diffusion-weighted magnetic resonance imaging. In order to understand this fascinating developmental process, we must establish the variability inherent in such a challenging imaging environment and how measurable quantities can be transformed into meaningful connectomes. We review techniques for reconstructing and studying the brain connectome and explore promising opportunities for in utero studies that could lead to more accurate measurement of structural properties and allow for more refined and insightful analyses of the fetal brain. Opportunities for more sophisticated analyses of the properties of the brain and its dynamic changes have emerged in recent years, based on the development of iterative techniques to reconstruct motion-corrupted diffusion-weighted data. Although reconstruction quality is greatly improved, the treatment of fundamental quantities like edge strength requires careful treatment because of the specific challenges of imaging in utero. There are intriguing challenges to overcome, from those in analysis due to both imaging limitations and the significant changes in structural connectivity, to further image processing to address the specific properties of the target anatomy and quantification into a developmental connectome.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"252 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83727347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Fetal Cardiac MRI 胎儿心脏MRI
Topics in Magnetic Resonance Imaging Pub Date : 2019-10-01 DOI: 10.1097/RMR.0000000000000218
Christopher W Roy, Joshua F P van Amerom, David A. Marini, Mike Seed, Christopher K Macgowan
{"title":"Fetal Cardiac MRI","authors":"Christopher W Roy, Joshua F P van Amerom, David A. Marini, Mike Seed, Christopher K Macgowan","doi":"10.1097/RMR.0000000000000218","DOIUrl":"https://doi.org/10.1097/RMR.0000000000000218","url":null,"abstract":"Abstract Magnetic resonance imaging (MRI) is an appealing technology for fetal cardiovascular assessment. It can be used to visualize fetal cardiac and vascular anatomy, to quantify fetal blood flow, and to quantify fetal blood oxygen saturation and hematocrit. However, there are practical limitations to the use of conventional MRI for fetal cardiovascular assessment, including the small size and high heart rate of the human fetus, the lack of conventional cardiac gating methods to synchronize data acquisition, and the potential corruption of MRI data due to maternal respiration and unpredictable fetal movements. In this review, we discuss recent technical advances in accelerated imaging, image reconstruction, cardiac gating, and motion compensation that have enabled dynamic MRI of the fetal heart.","PeriodicalId":39381,"journal":{"name":"Topics in Magnetic Resonance Imaging","volume":"26 1","pages":"235 - 244"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88210268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
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