No To Hattatsu最新文献

{"title":"[The significance of active vitamin B6 in pediatric neurological disease].","authors":"Harumi Yoshinaga, Hirokazu Oguni","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"114-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical medicine and medical research].","authors":"Mitsumasa Fukuda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"78"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34458325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A 6-month-old female patient who suffered clustering of afebrile seizures].","authors":"Toshiyuki Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"79-80"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34458326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The transition to adult health care for youth with developmental disorders].","authors":"Satoshi Takada, Tatsuya Koeda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"103-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The early rehabilitation in children with Down. Paying special attention to shuffling and comorbidities of developmental disorder].","authors":"Kazuyo Saito,&nbsp;Yukie Watanabe","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>There have been many reports on the effects of early rehabilitation in children with Down syndrome, which have demon- strated that early intervention improves motor skill acquisition and prevents a shuffling gait in these children. With regard to the mental development and mental health of these children, they are known to be friendly and social but some experience difficulties with nursing. Recently there have been a few reports on comorbidities of developmental disorders in Down syndrome. In the present research we studied both the motor and mental developments in children with Down syndrome, paying special attention to the shuffling gait and the comorbidi- ties of developmental disorder.</p><p><strong>Methods: </strong>Clinical records of 121 children with Down syndrome (age, 1-11 years; mean age, 3.8 years), who visited the Yokohama rehabilitation center, were investigated.</p><p><strong>Results: </strong>Despite early intervention, we found that 14 patients (11.9%) exhib- ited a shuffling gait. Concerning the comorbidities of the psychiatric developmental disorder, 21 patients (17.4%) had autism spectrum disorder (ASD)-like characteristic. The children with a shuffling gait appeared slow with regard to motor developmental milestones. They also had ASD-like characteristics.</p><p><strong>Conclusions: </strong>Children with Down syndrome needed early rehabilitation not only for its motor skill effects but also for mental support. In spite of early intervention, those with a shuffling gait needed special care owing to the comorbidities such as ASD-like characteristics. More research is needed to establish the prognosis of Down syndrome.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"122-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Treatment for self-injurious behavior in mentally handicapped populations--a report from our practice].","authors":"Ikumi Kimura,&nbsp;Hiroya Nishida,&nbsp;Naoto Yamaguchi,&nbsp;Mika Nagase,&nbsp;Junko Ohinata,&nbsp;Naoko Ishikawa,&nbsp;Michiko Kita,&nbsp;Katsutoshi Nakatani,&nbsp;Akira Yoneyama,&nbsp;Eiji Kitazumi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Self-injurious behavior (SIB) is a common problem in individuals with intellectual disabilities, yet its clinical management remains to be established. We aimed to clarify the background factors and profiles of SIB in mentally and physically handicapped subjects and subsequently examined the efficacy of treatments attempted in our practice in order to achieve a better understanding of SIB and appro- priate interventions in these populations.</p><p><strong>Methods: </strong>We surveyed 92 mentally handicapped subjects with SIB (including 25 females and 67 males, most of whom also had physical disabilities) as outpatients or inpatients of our institution using a retrospective questionnaire com- pleted by the corresponding doctors.</p><p><strong>Results: </strong>Regarding psychobehavioral complications, impulsive mood swings (such as sudden rage) were more frequent than other behaviors. As to probable triggers of SIB, the patient's physical condition (17 cases) and noise or the temperature of the surrounding environment (38 cases) were identified. A total of 81 of 92 patients were given a prescription for SIB. Risperidone was the most commonly prescribed drug (75 cases), found to be effective in 38 (50.6%) cases, whereas phenothiazine antipsychotics were often more effective in patients with profound SIB. SSRIs (selective serotonin reuptake inhibitors) were applied in 20 cases, being effective in only five (25%) patients and discontinued in 11 (55%) patients due to the onset of several side effects, including overexcitement. As an additional agent for mood control, the antiepileptic topiramate was effective in 10 (76.9%) of 13 cases. Aside from medication, equipment for elbow extension was beneficial in some of the patients with profound SIB.</p><p><strong>Conclusions: </strong>Pharmacological intervention is sometimes beneficial, albeit only partly. Clinicians must therefore also consider triggers and factors in the surrounding environment for the development of SIB in mentally handicapped individuals.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"117-21"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Introductory remarks].","authors":"Shin Nabatame, N. Mizushima","doi":"10.1163/ej.9780792312239.195-369.2","DOIUrl":"https://doi.org/10.1163/ej.9780792312239.195-369.2","url":null,"abstract":"Since the foundation of the Competition Programme, OECD-KPC in Feb. 24, 2004, we held 34 seminars with competition authorities in the Asia Pacific region. I have no doubt that competition authorities in Asia have strengthened professional capacity in the compeitition law and policy fields through learning and exchanging advanced theories and sharing experiences between participating countries. So far, 715 competition experts have participated from 36 countries.","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 3 1","pages":"174-6"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1163/ej.9780792312239.195-369.2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64583032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of quality of life in attention-deficit hyperactivity disorder children without comorbidity].","authors":"Fumikazu Sano,&nbsp;Hideaki Kanemura,&nbsp;Kakuro Aoyagi,&nbsp;Tomoko Tando,&nbsp;Kanji Sugita,&nbsp;Masao Aihara","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Object: </strong>Improving quality of life (QOL) is one of the most important therapeutic goals for children with attention-deficit hyperactiv- ity disorder (AD/HD). The aim of this study was to measure QOL in AD/HD children without comorbidity and to examine associations between QOL and clinical symptoms of AD/HD for targeting early intervention.</p><p><strong>Methods: </strong>Twenty-two enrolled patients and their parents completed the Questionnaire for Measuring Health-Related Quality of Life in Children (KINDL-R). Patients and teachers completed AD/HD rating scale-IV. Associations between QOL and clinical symptoms were assessed using t tests and correlations.</p><p><strong>Results: </strong>Mean total score of the self-reported KINDL-R was 70.8. No difference in total QOL score was seen between AD/HD children and controls; however, the self-esteem subscale rated by AD/HD children was significantly higher than that of controls (p < 0.001). Total KINDL-R score correlated negatively with AD/HD rating scale-IV rated by teachers (p < 0.05). A difference was observed between AD/HD children in a lower QOL group and their parents in a subscale regarding QOL at school.</p><p><strong>Conclusions: </strong>These findings suggest that evaluation of QOL in AD/HD children without comorbidity is useful for identifying AD/HD children who might benefit from early intervention.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"47 5","pages":"349-53"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34186217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Scintigraphic imaging in the diagnosis of failed intrathecal baclofen therapy: a case report of a 7-year-old boy with ventriculoperitoneal shunt].","authors":"Akiko Shibata,&nbsp;Mariko Yamamoto,&nbsp;Yu Watanabe,&nbsp;Hiroshi Terashima,&nbsp;Hirofumi Kashii,&nbsp;Masaya Kubota,&nbsp;Nobuhito Morota","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intrathecal baclofen (ITB) therapy is popular for the management of intractable spasticity. In 2007, the indications of ITB therapy expanded to include spasticity of children in Japan. In this report, we assessed the utility of radioisotopic scintigraphy in the diagnosis of failed ITB therapy. A 7-year-old boy with schizencephaly, hydrocephalus, and spastic quadriplegia had an ITB pump implanted. In his infancy, he had undergone ventriculoperitoneal shunt implantation. One month after the ITB operation, the ITB therapeutic effect diminished. Several examinations confirmed that the pump function was normal and catheter failure had not occurred. However, radioisotopic scintigraphy revealed that the baclofen had been washed out to blood circulation more rapidly than is typically observed. We considered two possible causes for this; obstruction of the cerebrospinal space due to kyphosis and excessive washout of celebrospinal fluid through the ventriculoperitoneal shunt. The catheter was moved to a more caudal site surgically, and his spasticity improved. The use of radioisotopic scintigraphy to identify the distribution of baclofen is an effective technique for investigation of baclofen pump system malfunction.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"47 5","pages":"367-71"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34186221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Relation between psychological development and respiratory management in patients with congenital central hypoventilation syndrome in Japan].","authors":"Kaori Irahara,&nbsp;Tomomi Ogata,&nbsp;Hiroshi Ozawa,&nbsp;Ushio Otaki,&nbsp;Keiichi Yamamoto,&nbsp;Takehiro Ishizuka,&nbsp;Kiyoshi Arimoto,&nbsp;Satoshi Kimiya,&nbsp;Koichi Arakawa,&nbsp;Kazuhiro Muramatsu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the psychological development of patients with congenital central hypoventilation syndrome (CCHS).</p><p><strong>Methods: </strong>We performed a questionnaire-based survey of 17 patients with CCHS aged over 7 years and assessed their clinical course, respiratory management, and psychological development.</p><p><strong>Results: </strong>CCHS was present at birth in 15 patients, of which eight presented with respiratory failure with a low Apgar score. Twelve patients required mechanical ventilation with intubation, and five received mask ventilation. All patients with intubation underwent tracheostomy between 1 and 12 months of age (median 5.5 months), and most of them had associated conditions such as Hirschsprung disease. Four of 12 patients with intubation were eventually switched to mask ventilation and one to diaphragm pacing and mask ventilation. The patients undergoing mask ventilation had relatively milder disease severity and had fewer complications than did the patients with intubation. The psychological development of patients who received tracheostomy ranged from normal to severe retardation. Retardation was more likely to be severe in patients who received tracheostomy in late infancy. All patients who received mask ventilation experienced borderline to moderate psychological retardation. This effect could be attributed to poor compliance with mask fitting.</p><p><strong>Conclusion: </strong>Our findings suggest that the psychological development of CCHS patients was influenced by hypoxia; tracheostomy and strict respiratory management since the neonatal period were needed for neurological protection.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"47 5","pages":"343-7"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34186216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}