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[Introductory remarks]. 【引言】。
No To Hattatsu Pub Date : 2016-05-01
Shin Nabatame, Noboru Mizushima
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引用次数: 0
[The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease]. [增强蛋白质降解系统在多谷氨酰胺介导的运动神经元疾病中发挥治疗作用]。
No To Hattatsu Pub Date : 2016-05-01
Hiroaki Adachi
{"title":"[The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease].","authors":"Hiroaki Adachi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 3","pages":"188-94"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34680667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Anti-MOG + neuromyelitis optica spectrum disorders treated with plasmapheresis]. 血浆置换治疗抗mog +视神经脊髓炎谱系障碍。
No To Hattatsu Pub Date : 2016-05-01
Azusa Oshiro, Sadao Nakamura, Kunihito Tamashiro, Kazuo Fujihara
{"title":"[Anti-MOG + neuromyelitis optica spectrum disorders treated with plasmapheresis].","authors":"Azusa Oshiro,&nbsp;Sadao Nakamura,&nbsp;Kunihito Tamashiro,&nbsp;Kazuo Fujihara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 10-year-old boy developed bilateral optic neuritis and myelitis after a suspected viral infection and appendicitis. Magnetic resonance imaging (MRI) showed multiple lesions in both optic nerves, the optic chiasm, and the spinal cord. Several small lesions were also observed in the cerebellum and cerebral white matter. The serum tested negative for anti-aquaporin (AQP)-4 antibody and positive for anti-myelin oligodendrocyte glycoprotein (MOG) antibody. The diagnosis was neuromyelitis optica spectrum disorder (NMOSD). Two courses of high-dose methylprednisolone were administered; however, only a small improvement in his visual acuity was achieved. He underwent 3 courses of plasma exchange to achieve sufficient visual acuity. After the serum anti-MOG antibody titer decreased to the cut-off level, oral prednisolone and azathioprine administration were also stopped, 10 months after onset. Recently, NMO and NMOSD cases positive for anti-MOG antibodies have been reported, which showed clinical features different from those of NMO cases positive for anti-AQP4 antibody. Although most of the reported cases responded to steroid therapy, plasma exchange was required in our case. Further analysis on larger numbers of cases is needed to establish treatments for anti-MOG antibody-positive NMO and NMOSD.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 3","pages":"199-203"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34680669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A 6-month-old female patient who suffered clustering of afebrile seizures (part 2)]. [一例6个月大的女性患者出现聚集性发热性癫痫发作(第二部分)]。
No To Hattatsu Pub Date : 2016-05-01
Toshiyuki Yamamoto
{"title":"[A 6-month-old female patient who suffered clustering of afebrile seizures (part 2)].","authors":"Toshiyuki Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 3","pages":"157-8"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34680661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Deployment and problems after the "Joint recommendations on sedation during MRI examination"]. 【“MRI检查中镇静联合建议”后的部署及问题】。
No To Hattatsu Pub Date : 2016-03-01
Seigo Korematsu, Hideo Yamanouchi
{"title":"[Deployment and problems after the \"Joint recommendations on sedation during MRI examination\"].","authors":"Seigo Korematsu,&nbsp;Hideo Yamanouchi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"107-10"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Future challenges and children's situation after the Great East Japan Earthquake]. [东日本大地震后未来的挑战和儿童的处境]。
No To Hattatsu Pub Date : 2016-03-01
Soichiro Tanaka, Atsushi Kamei
{"title":"[Future challenges and children's situation after the Great East Japan Earthquake].","authors":"Soichiro Tanaka,&nbsp;Atsushi Kamei","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"111-3"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A case of prolonged paroxysmal sympathetic hyperactivity]. [长时间阵发性交感神经亢进一例]。
No To Hattatsu Pub Date : 2016-03-01
Akiko Yamamoto, Shuhei Ide, Yuji Iwasaki, Makiko Kaga, Masataka Arima
{"title":"[A case of prolonged paroxysmal sympathetic hyperactivity].","authors":"Akiko Yamamoto,&nbsp;Shuhei Ide,&nbsp;Yuji Iwasaki,&nbsp;Makiko Kaga,&nbsp;Masataka Arima","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report the case of a 4-year-old girl who presented with paroxysmal sympathetic hyperactivity (PSH), after developing severe hypoxic-ischemic-encephalopathy because of cardiopulmonary arrest. She showed dramatic paroxysmal sympathetic activity with dystonia. She was treated with wide variety of medications against PSH, which were found to be effective in previous studies. Among them, morphine, bromocriptine, propranolol, and clonidine were effective in reducing the frequency of her attacks while gabapentin, baclofen, dantrolene, and benzodiazepine were ineffective. Though the paroxysms decreased markedly after the treatment, they could not be completely controlled beyond 500 days. Following the treatment, levels of plasma catecholamines and their urinary metabolites decreased to normal during inter- paroxysms. However, once a paroxysm had recurred, these levels were again very high. This case study is considered significant for two rea- sons. One is that PSH among children have been rarely reported, and the other is that this case of prolonged PSH delineated the transition of plasma catecholamines during the treatment. The excitatory: inhibitory ratio (EIR) model proposed by Baguley was considered while dis- cussing drug sensitivity in this case. Accumulation of similar case studies will help establish more effective treatment strategies and elucidate the pathophysiology of PSH.</p>","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"127-31"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Meet the experts: therapy of myasthenia gravis in childhood]. 【认识专家:小儿重症肌无力的治疗方法】。
No To Hattatsu Pub Date : 2016-03-01
Masafumi Morimoto, Kazuhiro Haginoya
{"title":"[Meet the experts: therapy of myasthenia gravis in childhood].","authors":"Masafumi Morimoto,&nbsp;Kazuhiro Haginoya","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"98-100"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recent state of Japan obstetric compensation system and its 2015 revision]. [日本产科赔偿制度近况及其2015年修订版]。
No To Hattatsu Pub Date : 2016-03-01
Atsuo Nezu, Yasuhiro Suzuki
{"title":"[Recent state of Japan obstetric compensation system and its 2015 revision].","authors":"Atsuo Nezu,&nbsp;Yasuhiro Suzuki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"101-2"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Promote further progresses in child neurology based on a global partnership of health professionals and scientists, bring joy to all children with neurological disorders]. [在卫生专业人员和科学家的全球伙伴关系基础上促进儿童神经病学的进一步进展，为所有患有神经系统疾病的儿童带来欢乐]。
No To Hattatsu Pub Date : 2016-03-01
Toshisaburo Nagai
{"title":"[Promote further progresses in child neurology based on a global partnership of health professionals and scientists, bring joy to all children with neurological disorders].","authors":"Toshisaburo Nagai","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39367,"journal":{"name":"No To Hattatsu","volume":"48 2","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34459298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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