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Extensive spinal epidural CSF collection following lumbar puncture. 腰椎穿刺后广泛收集脊髓硬膜外脑脊液。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2025-01-07 DOI: 10.1136/pn-2024-004413
Arun Rajaratnam, Nimasha Ekanayaka, Chandana Peiris, Bimsara Senanayake
{"title":"Extensive spinal epidural CSF collection following lumbar puncture.","authors":"Arun Rajaratnam, Nimasha Ekanayaka, Chandana Peiris, Bimsara Senanayake","doi":"10.1136/pn-2024-004413","DOIUrl":"https://doi.org/10.1136/pn-2024-004413","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mediterranean spotted fever presenting with rash and meningism. 地中海斑疹热，表现为皮疹和脑膜炎。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2025-01-03 DOI: 10.1136/pn-2024-004438
José Manuel Alcalá Ramírez Del Puerto, Maddalena Elena Urbano, Pablo Abizanda Saro, Adela María Maruri Pérez, Vicente Gajate García
{"title":"Mediterranean spotted fever presenting with rash and meningism.","authors":"José Manuel Alcalá Ramírez Del Puerto, Maddalena Elena Urbano, Pablo Abizanda Saro, Adela María Maruri Pérez, Vicente Gajate García","doi":"10.1136/pn-2024-004438","DOIUrl":"https://doi.org/10.1136/pn-2024-004438","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infratentorial superficial siderosis due to a spinal dural tear. 由硬脊膜撕裂引起的幕下浅表性铁沉着症。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2025-01-02 DOI: 10.1136/pn-2024-004382
Sarah Katherine Morgan, Kuhilan Gounder, Constantine Phatouros, Tom Jenkins
{"title":"Infratentorial superficial siderosis due to a spinal dural tear.","authors":"Sarah Katherine Morgan, Kuhilan Gounder, Constantine Phatouros, Tom Jenkins","doi":"10.1136/pn-2024-004382","DOIUrl":"https://doi.org/10.1136/pn-2024-004382","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral posterior reversible encephalopathy syndrome after an ipsilateral carotid endarterectomy. 同侧颈动脉内膜切除术后单侧后部可逆性脑病综合征。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-31 DOI: 10.1136/pn-2024-004448
Ali Al-Salahat, Seyed Amir Ebrahimzadeh, Mittal Prajapati
{"title":"Unilateral posterior reversible encephalopathy syndrome after an ipsilateral carotid endarterectomy.","authors":"Ali Al-Salahat, Seyed Amir Ebrahimzadeh, Mittal Prajapati","doi":"10.1136/pn-2024-004448","DOIUrl":"https://doi.org/10.1136/pn-2024-004448","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral femoral neck fractures and fixation failure due to stiff-person syndrome. 僵硬人综合征导致双侧股骨颈骨折及固定失败。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-25 DOI: 10.1136/pn-2024-004391
Daniel Whittam, Anthony Helm, Harry Tucker
{"title":"Bilateral femoral neck fractures and fixation failure due to stiff-person syndrome.","authors":"Daniel Whittam, Anthony Helm, Harry Tucker","doi":"10.1136/pn-2024-004391","DOIUrl":"10.1136/pn-2024-004391","url":null,"abstract":"<p><p>We describe a woman with stiff-person syndrome (SPS), whose muscle spasms resulted in sequential bilateral femoral neck fractures. Orthopaedic fixation of the first fracture was complicated by increased muscle spasm, fracture nonunion and ultimately metalwork fracture. SPS was diagnosed following the fracture of the contralateral femoral neck, neurology assessment and detection of high-titre antibodies to glutamic acid decarboxylase. Multidisciplinary management with high-dose benzodiazepines, intravenous immunoglobulin infusions, and bilateral total hip replacements achieved a good functional outcome. Spasms associated with SPS are a rare cause of pathological fractures and may cause orthopaedic fixation to fail. Early recognition and multidisciplinary care are essential to prevent additional morbidity.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A bedside sensory phenomenon that can help explain functional sensory symptoms. 一种有助于解释功能性感觉症状的床边感觉现象。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-20 DOI: 10.1136/pn-2024-004456
Stoyan Popkirov
{"title":"A bedside sensory phenomenon that can help explain functional sensory symptoms.","authors":"Stoyan Popkirov","doi":"10.1136/pn-2024-004456","DOIUrl":"https://doi.org/10.1136/pn-2024-004456","url":null,"abstract":"<p><p>Explaining basic illness mechanisms is an important step in communicating functional neurological symptoms. Clinical signs for motor symptoms, such as the Hoover test, have proven an excellent basis for mechanistic explanations. Here, I recommend a simple technique for eliciting tingling sensations through directed bodily attention, as a helpful experiential starting point for explanations of sensory gating and somatosensory amplification in patients with functional hyperaesthesia, paraesthesia and chronic pain.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tetrodotoxin toxicity: an increasing threat. 河豚毒素中毒：威胁与日俱增。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-14 DOI: 10.1136/pn-2024-004368
Emily Burton, Alastair Ward, Lachlan Tamlin, Shaddy El-Masri, Rudy Goh, Roula Ghaoui, Stephen Bacchi
{"title":"Tetrodotoxin toxicity: an increasing threat.","authors":"Emily Burton, Alastair Ward, Lachlan Tamlin, Shaddy El-Masri, Rudy Goh, Roula Ghaoui, Stephen Bacchi","doi":"10.1136/pn-2024-004368","DOIUrl":"10.1136/pn-2024-004368","url":null,"abstract":"<p><p>A man aged in his sixties presented to the emergency department with vomiting, dizziness and generalised weakness preceded by perioral and peripheral paraesthesias for several hours. He did not speak English and was visiting from overseas. Examination revealed multidirectional nystagmus, subtle bilateral ptosis, marked bilateral upper limb dysmetria and heel-shin ataxia, with mild proximal limb weakness. Brain imaging was unremarkable. Further history revealed the man had gone fishing and eaten a fish he had caught earlier that day. He was subsequently diagnosed with tetrodotoxin toxicity from pufferfish ingestion. He was managed supportively and made a complete recovery. Tetrodotoxicity has been hitherto considered rare outside of Southeast Asia, but rising water temperatures and human interventions have facilitated the migration of marine species containing tetrodotoxin to a wider geographical range.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurogenic disease with high CK: think muscle. 神经源性疾病与高CK：认为肌肉。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-05 DOI: 10.1136/pn-2024-004401
Andrea Barp, Paola Tonin, Salvatore Stano, Gaetano Nicola Vattemi, Marta Cheli, Giulia Marchetto, Matteo De Iorio, Riccardo Zuccarino
{"title":"Neurogenic disease with high CK: think muscle.","authors":"Andrea Barp, Paola Tonin, Salvatore Stano, Gaetano Nicola Vattemi, Marta Cheli, Giulia Marchetto, Matteo De Iorio, Riccardo Zuccarino","doi":"10.1136/pn-2024-004401","DOIUrl":"10.1136/pn-2024-004401","url":null,"abstract":"<p><p>HyperCKaemia is common in several myopathies but can accompany other disorders, including neuropathies. However, distinguishing neurogenic from myopathic hyperCKaemia is not always straightforward. A 58-year-old man had experienced muscle cramps and fatiguability since aged 3 years, with persistently high serum creatine kinase (CK). A positive family history prompted genetic testing for Charcot-Marie-Tooth disease type 1A, which was positive. However, his serum CK remained persistently high and neurological examination 17 years later identified diffuse muscle atrophy and weakness. Genetic testing for dystrophinopathy identified a novel missense variant on the <i>DMD</i> gene. Patients whose serum CK is in 'myopathic range', even those with definite neurogenic disease, should be investigated for additional myopathy, since this may require additional monitoring for pulmonary and cardiac complications.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sniffed levamisole-adulterated cocaine mimicking acute demyelinating encephalomyelitis. 嗅吸左旋咪唑掺假可卡因模拟急性脱髓鞘性脑脊髓炎。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-04 DOI: 10.1136/pn-2024-004343
Joshua Yap, Kayla Ward, Simon Broadley
{"title":"Sniffed levamisole-adulterated cocaine mimicking acute demyelinating encephalomyelitis.","authors":"Joshua Yap, Kayla Ward, Simon Broadley","doi":"10.1136/pn-2024-004343","DOIUrl":"10.1136/pn-2024-004343","url":null,"abstract":"<p><p>A 38-year-old man developed headache, dysarthria and dysphasia after insufflation of cocaine. Brain imaging showed multiple white matter lesions, suggesting acute disseminated encephalomyelitis (ADEM), but the clinical features were atypical for demyelination. These lesions may represent a levamisole-associated vascular endotheliopathy, with a mechanism similar to posterior reversible encephalopathy syndrome. Levamisole is a no longer used chemotherapeutic agent but is a legally acquirable veterinary antihelminthic and is often used to adulterate cocaine. Given the rise in cocaine-related hospitalisations, this case raises awareness of an important ADEM mimic.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive tetraparesis and bulbar symptoms. 进行性四肢麻痹和球症状。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-12-04 DOI: 10.1136/pn-2024-004394
Carolina Cunha, Henrique Coimbra de Lemos Queirós, Marco Almeida, Daniela Pereira, João Parente Freixo, Patrícia Marques, Fernando Matias, João Durães
{"title":"Progressive tetraparesis and bulbar symptoms.","authors":"Carolina Cunha, Henrique Coimbra de Lemos Queirós, Marco Almeida, Daniela Pereira, João Parente Freixo, Patrícia Marques, Fernando Matias, João Durães","doi":"10.1136/pn-2024-004394","DOIUrl":"10.1136/pn-2024-004394","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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