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Welcome to the mainland: general neurology's role in rescue from the islands of subspecialisation. 欢迎来到大陆：普通神经病学在拯救亚专业化孤岛中的作用。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004206
Steven Lewis
{"title":"Welcome to the mainland: general neurology's role in rescue from the islands of subspecialisation.","authors":"Steven Lewis","doi":"10.1136/pn-2024-004206","DOIUrl":"10.1136/pn-2024-004206","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"530-531"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crossword. 填字游戏
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004212
Phil E M Smith
{"title":"Crossword.","authors":"Phil E M Smith","doi":"10.1136/pn-2024-004212","DOIUrl":"10.1136/pn-2024-004212","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":"24 6","pages":"545-547"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurological disorders provoked by head and neck movement. 头颈部运动引发的神经系统疾病。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004160
Neil Watson
{"title":"Neurological disorders provoked by head and neck movement.","authors":"Neil Watson","doi":"10.1136/pn-2024-004160","DOIUrl":"10.1136/pn-2024-004160","url":null,"abstract":"<p><p>Neurologists encounter a range of neurological disorders triggered by head and neck movement, reflecting an array of underlying pathologies and producing diverse symptoms. This article provides a practically orientated review of 14 disorders and how to diagnose and manage them, including common disorders such as benign paroxysmal positional vertigo and uncommon entities such as arterial compression syndromes leading to stroke or syncope, mobile intraventricular masses and medication withdrawal states. The article considers atypical scenarios including unusual manifestations and important mimics and discusses controversial entities, as well as the risk of misattributing symptoms based on incidental imaging abnormalities. Guidelines are referenced where they exist, while in rarer situations, approaches taken in published cases are described, with the acknowledgement that management decisions are at the clinician's discretion.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"456-466"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal puncture through a large lumbar tattoo. 通过腰部大纹身进行脊椎穿刺。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004194
Sara García-Bellido Ruiz, Carlos Santos Martín, Alejandro Herrero San Martín, Carlos Pablo de Fuenmayor Fernández de la Hoz
{"title":"Spinal puncture through a large lumbar tattoo.","authors":"Sara García-Bellido Ruiz, Carlos Santos Martín, Alejandro Herrero San Martín, Carlos Pablo de Fuenmayor Fernández de la Hoz","doi":"10.1136/pn-2024-004194","DOIUrl":"10.1136/pn-2024-004194","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"522-523"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Shock. 震惊
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004201
Sophie Voase
{"title":"In Shock.","authors":"Sophie Voase","doi":"10.1136/pn-2024-004201","DOIUrl":"10.1136/pn-2024-004201","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"549"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140899910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary transthyretin amyloidosis presenting with prominent autonomic dysfunction. 遗传性转甲状腺素淀粉样变性，表现为突出的自主神经功能障碍。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2023-004048
Mary McCullagh, Sinead Hughes, Adam Canning, Seamus Napier, Julian Gillmore, Mark Owen McCarron
{"title":"Hereditary transthyretin amyloidosis presenting with prominent autonomic dysfunction.","authors":"Mary McCullagh, Sinead Hughes, Adam Canning, Seamus Napier, Julian Gillmore, Mark Owen McCarron","doi":"10.1136/pn-2023-004048","DOIUrl":"10.1136/pn-2023-004048","url":null,"abstract":"<p><p>A 56-year-old man reported 2 years of slowly progressive exertional fatigue, presyncope, paraesthesia, generalised weakness and nocturnal bowel frequency. He had an abnormal Valsalva ratio and significant postural hypotension. Serum N-terminal pro-B-type natriuretic peptide and troponin T were elevated. Transthoracic echocardiogram identified thickening of the biventricular walls, interatrial septum and atrioventricular valve leaflets. Global longitudinal strain was reduced with relative apical sparing, suspicious for cardiac amyloidosis. Technetium-99m and 3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy supported a diagnosis of transthyretin amyloidosis (ATTR). However, urinary Bence Jones protein (kappa) was identified despite a normal kappa/lambda light chain ratio and no serum paraprotein. Bone marrow and buccal biopsy provided histological confirmation of amyloid. The bone marrow had no evidence of plasma cell dyscrasia but positive TTR immunohistochemistry. The patient had a T60A genetic mutation for hereditary ATTR. Overlapping cardiac and autonomic symptoms prompt an amyloid workup, which then must distinguish AL amyloid from ATTR pathology.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"511-514"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Watch for inclusion body myositis. 注意包涵体肌炎。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004256
Martijn Thomas Wijburg, Joost Raaphorst
{"title":"Watch for inclusion body myositis.","authors":"Martijn Thomas Wijburg, Joost Raaphorst","doi":"10.1136/pn-2024-004256","DOIUrl":"10.1136/pn-2024-004256","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"524-525"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent unilateral facial nerve palsy in acute lymphocytic leukaemia. 急性淋巴细胞白血病复发性单侧面神经麻痹。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004175
Robert Kassinger, Amir Adeli
{"title":"Recurrent unilateral facial nerve palsy in acute lymphocytic leukaemia.","authors":"Robert Kassinger, Amir Adeli","doi":"10.1136/pn-2024-004175","DOIUrl":"10.1136/pn-2024-004175","url":null,"abstract":"<p><p>A man in his mid-20s developed three episodes of right facial weakness over 5 months. He had a history of B-cell acute lymphoblastic leukaemia (ALL) in remission following allogenic stem cell transplantation. MR scan of brain during the second presentation showed facial nerve enhancement; cerebrospinal fluid (CSF) cytology and flow cytometry were negative. Re-assessment at the third presentation identified CSF B-lymphoblasts, and he was subsequently treated for central nervous system relapse of leukaemia. This case highlights an infrequent presenting symptom of ALL relapse and a rare cause of recurrent facial nerve palsy.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"503-506"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebrospinal fluid HIV RNA escape syndrome. 脑脊液 HIV RNA 逸出综合征。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2024-004117
Sian Nasse, Jonathan Underwood, Tom A T Hughes
{"title":"Cerebrospinal fluid HIV RNA escape syndrome.","authors":"Sian Nasse, Jonathan Underwood, Tom A T Hughes","doi":"10.1136/pn-2024-004117","DOIUrl":"10.1136/pn-2024-004117","url":null,"abstract":"<p><p>A 54-year-old man with treated HIV developed a subacute deterioration of speech, mobility and cognition. Cerebrospinal fluid (CSF) analysis showed a raised protein and a discordant CSF HIV RNA paired with plasma HIV RNA, confirming the diagnosis of CSF HIV RNA escape syndrome. It is important to consider this diagnosis in people with treated HIV who develop new neurological symptoms.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"507-510"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frailty in stroke. 中风后体弱多病。
IF 2.4
PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI: 10.1136/pn-2023-003833
Fariha Naeem, Terry Quinn
{"title":"Frailty in stroke.","authors":"Fariha Naeem, Terry Quinn","doi":"10.1136/pn-2023-003833","DOIUrl":"10.1136/pn-2023-003833","url":null,"abstract":"<p><p>Stroke is predominantly a condition of older age. So, it seems sensible that specialists working in stroke services should understand the primary clinical syndrome of ageing-frailty. Recent studies have highlighted the prevalence of frailty in stroke and its associated poor outcomes, yet frailty does not feature prominently in stroke research, practice or policy. Frailty-informed stroke care may differ from the interventional management that dominates contemporary practice. However, this is not therapeutic nihilism. A person-centred approach ensures that every care decision is appropriate and based on a shared understanding of the person's goals and likely prognosis. We present a primer on frailty in stroke, describing definition(s), epidemiology and prognostic implications. We discuss the challenges surrounding assessment and management of frailty in stroke units and offer practical guidance suitable for the stroke clinician.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":"448-455"},"PeriodicalIF":2.4,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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