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Periprocedural antithrombotic management for lumbar puncture: Association of British Neurologists 2026 guideline summary update. 腰椎穿刺围手术期抗血栓管理：英国神经学家协会2026指南总结更新。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-20 DOI: 10.1136/pn-2026-005351
Katherine C Dodd, Fayyaz Ahmed, Michael Desborough, Ruth Dobson, Hedley C A Emsley, Khaizer Rizvi, Suresh Kumar Chhetri
{"title":"Periprocedural antithrombotic management for lumbar puncture: Association of British Neurologists 2026 guideline summary update.","authors":"Katherine C Dodd, Fayyaz Ahmed, Michael Desborough, Ruth Dobson, Hedley C A Emsley, Khaizer Rizvi, Suresh Kumar Chhetri","doi":"10.1136/pn-2026-005351","DOIUrl":"10.1136/pn-2026-005351","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversible cerebral vasoconstriction syndrome complicated by bilateral intracerebral haemorrhage. 可逆性脑血管收缩综合征并发双侧脑出血。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-20 DOI: 10.1136/pn-2026-005350
Zineb Lahlou, Ramona Alice Aastrand, Trine Stavngaard, Steven Haugbøll, Mona Ameri Chalmer, Daniel Kondziella, Peter Birkeland
{"title":"Reversible cerebral vasoconstriction syndrome complicated by bilateral intracerebral haemorrhage.","authors":"Zineb Lahlou, Ramona Alice Aastrand, Trine Stavngaard, Steven Haugbøll, Mona Ameri Chalmer, Daniel Kondziella, Peter Birkeland","doi":"10.1136/pn-2026-005350","DOIUrl":"https://doi.org/10.1136/pn-2026-005350","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zosteriform herpes simplex virus type 2 presenting as Brown-Séquard syndrome in an immunocompromised man. 带状疱疹样单纯疱疹病毒2型在免疫功能低下的男性中表现为布朗-萨姆夸德综合征。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-20 DOI: 10.1136/pn-2026-005379
Jordan Rex Wagner, Roberta Potamianos, Anthony Khoo
{"title":"Zosteriform herpes simplex virus type 2 presenting as Brown-Séquard syndrome in an immunocompromised man.","authors":"Jordan Rex Wagner, Roberta Potamianos, Anthony Khoo","doi":"10.1136/pn-2026-005379","DOIUrl":"https://doi.org/10.1136/pn-2026-005379","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute intermittent porphyria: abdominal pain, weight loss and acute neuropathy. 急性间歇性卟啉症：腹痛、体重减轻、急性神经病变。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-16 DOI: 10.1136/pn-2026-005418
Dilini Chandrisiri, Benjamin Mcloughlin, Jose Mosquera, Peter Arthur-Farraj, Belén González-Herrero
{"title":"Acute intermittent porphyria: abdominal pain, weight loss and acute neuropathy.","authors":"Dilini Chandrisiri, Benjamin Mcloughlin, Jose Mosquera, Peter Arthur-Farraj, Belén González-Herrero","doi":"10.1136/pn-2026-005418","DOIUrl":"https://doi.org/10.1136/pn-2026-005418","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Homozygous PRRT2 mutation causing a spectrum of paroxysmal neurological symptoms responsive to sodium channel blockers. 纯合子PRRT2突变引起对钠通道阻滞剂反应的一系列阵发性神经症状。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-12 DOI: 10.1136/pn-2026-005269
Aaron Ben-Joseph, Amira Amsha, Lina Nashef
{"title":"Homozygous PRRT2 mutation causing a spectrum of paroxysmal neurological symptoms responsive to sodium channel blockers.","authors":"Aaron Ben-Joseph, Amira Amsha, Lina Nashef","doi":"10.1136/pn-2026-005269","DOIUrl":"https://doi.org/10.1136/pn-2026-005269","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recognising motor impersistence at the bedside. 认识到床边的运动不持久。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-08 DOI: 10.1136/pn-2026-005163
Harry Knights, Mena Farag, Michael J Murphy, Sangeerthana Rajagopal, Edward J Wild
{"title":"Recognising motor impersistence at the bedside.","authors":"Harry Knights, Mena Farag, Michael J Murphy, Sangeerthana Rajagopal, Edward J Wild","doi":"10.1136/pn-2026-005163","DOIUrl":"https://doi.org/10.1136/pn-2026-005163","url":null,"abstract":"","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Migraine: diagnosis and treatment in primary and secondary care. 偏头痛：初级和二级保健的诊断和治疗。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-07 DOI: 10.1136/pn-2026-005167
Fayyaz Ahmed, Sophie Ramana Dorsey, Callum Duncan
{"title":"Migraine: diagnosis and treatment in primary and secondary care.","authors":"Fayyaz Ahmed, Sophie Ramana Dorsey, Callum Duncan","doi":"10.1136/pn-2026-005167","DOIUrl":"https://doi.org/10.1136/pn-2026-005167","url":null,"abstract":"<p><p>Migraine is the most prevalent neurological disorder presenting to primary and secondary care. It can be severely disabling. Its effective management improves quality of life of our patients. Over the last few decades, new acute and preventive treatment options have arrived that have changed the landscape of how migraine is managed. This article provides clinical practice guidelines intended to support clinicians with acute and chronic management of migraine.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuromycoses: recognition and management in clinical practice. 神经真菌病：临床的认识与处理。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-06 DOI: 10.1136/pn-2026-005263
Michael Trubshaw, Maeve Barlow, Camila Nagoda Niklewicz, Alvaro Sanchez Martinez, Joseph Parker, Martin Montes, Mara Waters, Rob Arts, Patricia McNamara, Neil Stone
{"title":"Neuromycoses: recognition and management in clinical practice.","authors":"Michael Trubshaw, Maeve Barlow, Camila Nagoda Niklewicz, Alvaro Sanchez Martinez, Joseph Parker, Martin Montes, Mara Waters, Rob Arts, Patricia McNamara, Neil Stone","doi":"10.1136/pn-2026-005263","DOIUrl":"https://doi.org/10.1136/pn-2026-005263","url":null,"abstract":"<p><p>Neuromycoses encompass fungal infections of the central nervous system (CNS). Their prevalence is increasing worldwide, with significant morbidity and mortality. Many carry a high mortality and so a knowledge of these conditions is important to facilitate rapid identification and treatment. There are no effective laboratory diagnostics for many neuromycoses. Negative cultures, absence of systemic inflammation and normal cerebrospinal fluid results do not exclude neuromycoses. Diagnosis can however often be deduced based on the specific constellation of exposure, travel and host factors. Management is difficult due to paucity of evidence, limited CNS penetration of antifungal agents and their significant toxicity. It is important to identify the causative organism due to highly variable susceptibility profiles. Treatment success is primarily evaluated based on symptom improvement. This review aims to arm clinicians with the broad knowledge required to diagnose and treat these rare, yet important, conditions with significant clinical consequences.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linear scleroderma 'en coup de sabre'. 线性硬皮病“刀下政变”。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-10-06 DOI: 10.1136/pn-2025-004882
Patxi Zavala Gottau, Francisco Caiza-Zambrano, Luis Ariel Miquelini, Maria Sol Pacha, Diego Tripodi, Yemina Neme, Mauricio Agustin Benetti, Andrea Dolores Ezquiaga, Mauricio Jiménez, Andrea Gomez, Félix Vigovich, Oscar Adolfo Martínez
{"title":"Linear scleroderma 'en coup de sabre'.","authors":"Patxi Zavala Gottau, Francisco Caiza-Zambrano, Luis Ariel Miquelini, Maria Sol Pacha, Diego Tripodi, Yemina Neme, Mauricio Agustin Benetti, Andrea Dolores Ezquiaga, Mauricio Jiménez, Andrea Gomez, Félix Vigovich, Oscar Adolfo Martínez","doi":"10.1136/pn-2025-004882","DOIUrl":"10.1136/pn-2025-004882","url":null,"abstract":"<p><p>Linear scleroderma 'en coup de sabre' is a rare condition characterised by inflammation and fibrosis of the skin and underlying tissues; it rarely presents in adults. The adult-onset form seldom has extracutaneous manifestations, but those that occur are usually neurological. A 43-year-old woman with epilepsy had a scar-like lesion on her forehead. The MR brain scan showed focal cortical atrophy and white matter changes on the same side as the skin lesion. Skin biopsy identified hyaline sclerosis of the reticular dermis consistent with scleroderma. Her clinical condition stabilised on mycophenolate mofetil. Although uncommon in adults, it is important to consider this rare disease in adults with scalp lesions who have epileptic seizures.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary spastic paraplegia: a practical approach. 遗传性痉挛性截瘫：一种实用方法。
IF 2.5
PRACTICAL NEUROLOGY Pub Date : 2026-09-30 DOI: 10.1136/pn-2026-005344
Maeve Bradley, Aicha Kalfat, Richard A Walsh, Tim Lynch, Conor Fearon, Henry Houlden
{"title":"Hereditary spastic paraplegia: a practical approach.","authors":"Maeve Bradley, Aicha Kalfat, Richard A Walsh, Tim Lynch, Conor Fearon, Henry Houlden","doi":"10.1136/pn-2026-005344","DOIUrl":"https://doi.org/10.1136/pn-2026-005344","url":null,"abstract":"<p><p>Hereditary spastic paraplegia (HSP) comprises a clinically and genetically diverse group of inherited neurodegenerative disorders unified by slowly progressive, usually symmetrical lower-limb spasticity secondary to corticospinal tract degeneration. For practising neurologists, the first step is recognising when a presentation is consistent with HSP and when it is not, and then carefully excluding treatable causes. We outline a pragmatic approach to assessing HSP, highlighting the broad clinical spectrum, 'red flags' that should trigger re-evaluation and the common acquired and genetic mimics. We summarise the relevant clinical and supportive investigations that can narrow the differential diagnosis. We also discuss the strengths and limitations of contemporary genetic testing. Finally, we focus on practical management: multidisciplinary care, spasticity treatments, and proactive recognition and management of additional symptoms outside of spasticity.</p>","PeriodicalId":39343,"journal":{"name":"PRACTICAL NEUROLOGY","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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