{"title":"[Interictal burden of migraine and its evaluations: a literature review].","authors":"Tsubasa Takizawa, Ryo Takemura, Hisaka Igarashi, Yasuhiko Matsumori, Minako Sato, Kaname Ueda","doi":"10.5692/clinicalneurol.cn-002016","DOIUrl":"10.5692/clinicalneurol.cn-002016","url":null,"abstract":"<p><p>We conducted a targeted literature review on patient burden during the interictal period of migraine. The results of the literature review revealed that: (1) migraine-associated burden persists into the interictal period and is not confined to the headache episodes themselves; (2) anxiety over the possible recurrence of headache episodes is a factor that reduces daily activities and quality of life (QOL); and (3) prophylactic treatment with calcitonin gene-related peptide (CGRP) antibody drugs may reduce the burden during the interictal period. From these findings, it is considered important in migraine treatment to identify the unmet needs of patients, including the burden during the interictal period, and to select an appropriate treatment method based on the burden experienced by individual patients.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"8-15"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Rheumatoid meningitis without arthritis presenting as widespread symmetrical high-intensity lesions along cerebral sulci on diffusion-weighted MRI: a case report].","authors":"Takanobu Kita, Hiroaki Okada, Seiji Takenouchi, Yoshiyuki Nakai, Masahiro Kanai, Keiji Yamaguchi","doi":"10.5692/clinicalneurol.cn-002022","DOIUrl":"10.5692/clinicalneurol.cn-002022","url":null,"abstract":"<p><p>A 52-year-old woman presented with the subacute onset of pantalgia, fever and consciousness disturbance. MRI revealed widespread symmetrical high-intensity areas along the sulci in both cerebral hemispheres on diffusion-weighted imaging (DWI). Rheumatoid meningitis was suspected based on elevated levels of anti-cyclic citrullinated peptide antibodies (ACPA) in both serum and cerebrospinal fluid (CSF), as well as an elevated ACPA index. Brain biopsy revealed marked infiltration of inflammatory cells in the subarachnoid space, confirming the diagnosis of rheumatoid meningitis. The patient fully recovered after receiving six courses of steroid pulse therapy, followed by postremission therapy. Diagnosing cases without arthritis can be challenging, but testing for ACPA and evaluating the ACPA index can be useful for both diagnosis and assessing therapeutic efficacy in cases of suspected rheumatoid meningitis.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Case of ictal aphasia and post-ictal aphasia due to focal epilepsy associated with cerebral hemorrhage].","authors":"Arisa Yamamoto, Kosuke Yoshida, Yasuhiro Suzuki, Kenji Kuroda, Takashi Kimura, Yoko Aburakawa","doi":"10.5692/clinicalneurol.cn-001954","DOIUrl":"10.5692/clinicalneurol.cn-001954","url":null,"abstract":"<p><p>The patient was a 69-year-old right-handed woman. She had sensory aphasia, and the brain MRI revealed a subacute phase hemorrhage in the left subcortical temporal lobe. We speculated that the patient had post-ictal aphasia due to symptomatic epileptic seizures associated with cerebral hemorrhage. Seven months later, she was readmitted to the hospital with sensory aphasia; however, this time, the brain MRI FLAIR demonstrated high signal in the left medial temporal lobe and thalamic pillow. Furthermore, the electroencephalogram showed periodic discharges focused on the left temporal region. <sup>123</sup>I-IMP SPECT of cerebral blood flow indicated a cluster within the medial left temporal lobe. Aphasia associated with nonconvulsive seizures was considered. Sudden onset sensory aphasia should be differentiated from ictal and post-ictal aphasias.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"22-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2025-01-01DOI: 10.5692/clinicalneurol.65_4_proceedings2
{"title":"[The Proceedings of the 246th Kyushu Regional Meeting of the Japanese Society of Neurology].","authors":"","doi":"10.5692/clinicalneurol.65_4_proceedings2","DOIUrl":"https://doi.org/10.5692/clinicalneurol.65_4_proceedings2","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":"65 4","pages":"297-302"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2025-01-01DOI: 10.5692/clinicalneurol.65_6_proceedings4
{"title":"[The Proceedings of the 247th Kyushu Regional Meeting of the Japanese Society of Neurology].","authors":"","doi":"10.5692/clinicalneurol.65_6_proceedings4","DOIUrl":"https://doi.org/10.5692/clinicalneurol.65_6_proceedings4","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":"65 6","pages":"483-489"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2025-01-01DOI: 10.5692/clinicalneurol.65_7_proceedings1
{"title":"[The Proceedings of the 2025 Chugoku-Shikoku Regional Post Graduate Education Meeting].","authors":"","doi":"10.5692/clinicalneurol.65_7_proceedings1","DOIUrl":"https://doi.org/10.5692/clinicalneurol.65_7_proceedings1","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":"65 7","pages":"543-545"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}