Clinical NeurologyPub Date : 2025-01-01DOI: 10.5692/clinicalneurol.65_1_proceedings1
{"title":"[The Proceedings of the 250th Kanto-Koshinetsu Regional Meeting of the Japanese Society of Neurology].","authors":"","doi":"10.5692/clinicalneurol.65_1_proceedings1","DOIUrl":"https://doi.org/10.5692/clinicalneurol.65_1_proceedings1","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":"65 1","pages":"55-70"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2025-01-01DOI: 10.5692/clinicalneurol.65_1_proceedings2
{"title":"[The Proceedings of the 245th Kyushu Regional Meeting of the Japanese Society of Neurology].","authors":"","doi":"10.5692/clinicalneurol.65_1_proceedings2","DOIUrl":"https://doi.org/10.5692/clinicalneurol.65_1_proceedings2","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":"65 1","pages":"71-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Early diagnosis of a long spinal cord infarction lesion based on concurrent erector spinae muscle infarction: a case report].","authors":"Takuma Kato, Keisuke Imai, Takehiro Yamada, Masanori Cho, Toshi Sai, Tetsuya Ioku","doi":"10.5692/clinicalneurol.cn-002029","DOIUrl":"10.5692/clinicalneurol.cn-002029","url":null,"abstract":"<p><p>We present a case of a 53-year-old man who was admitted with lower back pain and bilateral lower limb weakness. Neurologically, he exhibited paralysis of both lower limbs, complete sensory loss below the 10th thoracic spinal level, and bladder and rectal dysfunction. Spinal MRI revealed intramedullary high-signal lesions extending from the 10th vertebral level to the conus medullaris on diffusion-weighted and T<sub>2</sub>-weighted images. By the 10th day, the extensive intramedullary lesion had progressed to the 2nd vertebral level. Although aortic angiography on the 3rd day showed no vascular abnormalities, concurrent infarction of the paraspinal muscles at the 2nd lumbar vertebral level was confirmed. Based on the spinal vascular anatomy, it was deduced that both the spinal cord and the paraspinal muscle lesions had the same vascular etiology. Therefore, the spinal cord lesion was diagnosed early as spinal cord infarction. In cases of acute spinal symptoms, the coexistence of paraspinal muscle infarction observed on contrast-enhanced CT can assist in diagnosing spinal cord infarction.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"890-897"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A retrospective study of mechanical thrombectomy in very elderly patients over 90 years old with cerebral infarction].","authors":"Yuki Nakamura, Rintaro Yokoyama, Seiichiro Imataka, Takehiro Saga, Koichi Haraguchi, Shin Hisahara","doi":"10.5692/clinicalneurol.cn-002017","DOIUrl":"10.5692/clinicalneurol.cn-002017","url":null,"abstract":"<p><p>We retrospectively investigated mechanical thrombectomy (MT) in nonagenarians and older with cerebral infarction. Analysis of 21 consecutive patients showed favorable outcomes (improved modified Rankin scale [mRS] 0-2 or returned prestroke mRS) in 33.3% and poor outcome (mRS 5 or 6) in 52.4%. Factors related to favorable outcomes remain unknown, but the overall results of MT were good. MT is effective for the treatment of very elderly patients and further research is required to predict prognosis.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"898-900"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2024-12-21Epub Date: 2024-11-17DOI: 10.5692/clinicalneurol.cn-002012
Syuichi Tetsuka
{"title":"[Is the frequency of head MRI lesions reduced in Wernicke's encephalopathy associated with alcoholism?]","authors":"Syuichi Tetsuka","doi":"10.5692/clinicalneurol.cn-002012","DOIUrl":"10.5692/clinicalneurol.cn-002012","url":null,"abstract":"","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"904-905"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Importance of early treatment and quantitative evaluation of enzyme replacement therapy for Pompe disease: alglucosidase alfa post-marketing surveillance additional analysis].","authors":"Yoshinori Sunaga, Tatsuro Sakashita, Tadashi Koga, Takayuki Sawada, Shiho Yamane, Mitsunobu Ikeda","doi":"10.5692/clinicalneurol.cn-001894","DOIUrl":"10.5692/clinicalneurol.cn-001894","url":null,"abstract":"<p><p>We conducted an additional analysis using the data from the post-marketing surveillance of Alglucosidase alfa for Pompe disease. We aimed to investigate the changes in the percentage of predicted forced vital capacity (%FVC) and the changes in the distance of the 6-min walk test (6MWT) by overall improvement and to investigate the %FVC change by the duration from symptom onset to survey registration (shorter/longer groups) using a linear mixed model. Thirty-seven and eighteen survey participants had %FVC and 6MWT data available, respectively; of the patients whose overall improvement was rated as \"relatively improved,\" %FVC and 6MWT worsened in 71.4% and 66.7%, respectively. The %FVC at the survey registration estimated using a linear mixed model was significantly higher in the shorter group than in the longer group (P = 0.0413). The estimated slope of %FVC was significantly lower in the shorter group than in the longer group (P = 0.0051). These results suggest the importance of early treatment initiation and quantitative evaluation of each symptom.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"866-877"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Initiatives for supporting the health care transition in various regions: activities of transitional care support centers].","authors":"Yoko Mochizuki, Katsuhisa Ogata, Satoko Kumada, Tomihiro Imai, Chikako Akahoshi, Akiyo Hineno, Rie Kitahara, Ichiro Yabe, Hideki Mochizuki","doi":"10.5692/clinicalneurol.cn-002033","DOIUrl":"10.5692/clinicalneurol.cn-002033","url":null,"abstract":"<p><p>The Japanese Society of Neurology's Special Committee on Measures for Transition from Pediatric to Adult Health Care held a workshop to discuss the activities of the transitional care support centers (TCSCs). The following points were addressed: (1) from Kanagawa Prefecture, the activities of the TCSC, which is set up alongside the Intractable Disease Consultation Support Center and the Intractable Disease Information Coordination Center, separated from medical institutions, and the efforts addressing cases of difficult transitions and consultations where patients cannot transition from specific pediatric chronic diseases to designated intractable diseases; (2) from Nagano Prefecture, the supporting the health care transition undertaken by the neurologist as intractable disease medical coordinator, and (3) the efforts of the transitional health care support coordinator at the TCSC established at the university hospital in collaboration with the Nagano Children's Hospital and the government. For the creation of a seamless support system, we hope that the pioneering activities reported at this time will spread nationwide.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"861-865"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical NeurologyPub Date : 2024-12-21Epub Date: 2024-11-16DOI: 10.5692/clinicalneurol.cn-001969
Yukito Ueda, Ko Matsuo, Kana Matsuda, Ryo Momosaki, Akihiro Shindo, Hidekazu Tomimoto
{"title":"[Behavioral variant of frontotemporal dementia with stereotypic speech: a case report].","authors":"Yukito Ueda, Ko Matsuo, Kana Matsuda, Ryo Momosaki, Akihiro Shindo, Hidekazu Tomimoto","doi":"10.5692/clinicalneurol.cn-001969","DOIUrl":"10.5692/clinicalneurol.cn-001969","url":null,"abstract":"<p><p>A patient with behavioral variant frontotemporal dementia presented with stereotypic speech. The 85-year-old right-handed man had progressive language disorder over 2 years, with changes in eating behavior. His verbal output consisted mainly of the stereotypic speech; his articulation was mildly distorted, but his speech was intelligible. Spontaneous speech was rare, but there was no evidence of difficulty in initiating speech or effort. MRI of the head showed atrophy of the left frontal lobe, mainly in the superior, middle, and inferior frontal gyrus. Cerebral blood flow SPECT showed decreased cerebral blood flow in the same areas and in the left basal ganglia. We diagnosed behavioral variant frontotemporal dementia based on the symptoms, progression, and lesions. The stereotypic speech was judged to be non-meaningful recurrent utterance.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"878-883"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}