发布求助
文献互助 智能选刊 最新文献

Adverse Drug Reaction Bulletin最新文献

筛选
英文 中文
Adverse effects of activated charcoal used for the treatment of poisoning 用于治疗中毒的活性炭的副作用
Adverse Drug Reaction Bulletin Pub Date : 2011-02-01 DOI: 10.1097/FAD.0b013e328345389e
Z. Qureshi, M. Eddleston
{"title":"Adverse effects of activated charcoal used for the treatment of poisoning","authors":"Z. Qureshi, M. Eddleston","doi":"10.1097/FAD.0b013e328345389e","DOIUrl":"https://doi.org/10.1097/FAD.0b013e328345389e","url":null,"abstract":"The incidence of adverse effects of activated charcoal in poisoned patients is unclear. We performed a search of PubMed, EMBASE, and Ovid to identify large cohorts, and both randomized and pseudorandomized controlled trials, finding nine articles. The most commonly described adverse events were vomiting, aspiration, and intubation. Activated charcoal did not increase the incidence of these adverse effects. Other adverse events such as bowel obstruction, corneal abrasions, electrolyte disturbances, and seizures were rarely reported in the trials. Activated charcoal was associated with few clinically significant adverse events in the treatment of poisoned patients.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"1023–1026"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e328345389e","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Safety of ciprofloxacin in neonates with sepsis 环丙沙星治疗新生儿败血症的安全性
Adverse Drug Reaction Bulletin Pub Date : 2010-12-01 DOI: 10.1097/FAD.0b013e328342564b
M. Bonati, C. Pandolfini, F. Kaguelidou, É. Jacqz-Aigrain, M. Turner, I. Choonara
{"title":"Safety of ciprofloxacin in neonates with sepsis","authors":"M. Bonati, C. Pandolfini, F. Kaguelidou, É. Jacqz-Aigrain, M. Turner, I. Choonara","doi":"10.1097/FAD.0b013e328342564b","DOIUrl":"https://doi.org/10.1097/FAD.0b013e328342564b","url":null,"abstract":"Newborn sepsis is a major cause of child mortality across the world. Strategies for prevention and treatment have the potential to save many newborns from a sepsis-related death. Among the various parenteral antibiotic options possible, there is considerable experience with the use of penicillins, cephalosporins, and aminoglycosides. Ciprofloxacin is also increasingly accepted as safe in the neonate. However, the available evidence is not of high quality, and adequate research is required to specifically address dosage schedules, safety, and efficacy of ciprofloxacin to lead to established interventions to reduce morbidity and mortality for neonatal sepsis.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"1019–1022"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e328342564b","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Pharmacogenetics and adverse drug reactions 药物遗传学和药物不良反应
Adverse Drug Reaction Bulletin Pub Date : 2010-10-01 DOI: 10.1097/FAD.0b013e328340bc88
R. Ferner, J. Aronson
{"title":"Pharmacogenetics and adverse drug reactions","authors":"R. Ferner, J. Aronson","doi":"10.1097/FAD.0b013e328340bc88","DOIUrl":"https://doi.org/10.1097/FAD.0b013e328340bc88","url":null,"abstract":"The rapidly expanding discipline of pharmacogenetics has helped to explain the mechanisms of susceptibility to several adverse drug reactions. The molecular details of the ‘classical’ adverse reactions, including malignant hyperthermia, haemolysis in patients with glucose-6-phosphatase deficiency, and acute porphyrias, have become clearer. In addition, associations have emerged between adverse reactions and various polymorphisms that affect drug action. Examples include associations between the human leucocyte-associated antigen HLA B*5701 and hypersensitivity reactions to flucloxacillin and to the HIV protease inhibitor abacavir; between HLA B*1502 and toxic epidermal necrolysis induced in Han Chinese by antiepileptic drugs; between ion-channel mutations and drug-induced torsade de pointes; and between alterations in mitochondrial DNA and several rare adverse effects. The task of identifying individuals susceptible to adverse drug reactions should gradually become easier as more pharmacogenetic associations are described.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"1015–1018"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e328340bc88","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
ABCB1 (P-glycoprotein) and the clinical pharmacology of adverse drug reactions ABCB1 (p -糖蛋白)与药物不良反应的临床药理学研究
Adverse Drug Reaction Bulletin Pub Date : 2010-08-01 DOI: 10.1097/FAD.0b013e32833ee68a
RE Ferner
{"title":"ABCB1 (P-glycoprotein) and the clinical pharmacology of adverse drug reactions","authors":"RE Ferner","doi":"10.1097/FAD.0b013e32833ee68a","DOIUrl":"https://doi.org/10.1097/FAD.0b013e32833ee68a","url":null,"abstract":"The ABCB1 (P-glycoprotein) gene plays an important role in how drugs are metabolized, distributed and eliminated in man; these are the factors which determine whether in any particular individual a drug has an inadequate, therapeutic or toxic effect.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"1011–1014"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e32833ee68a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Monitoring of patients treated with antihypertensive therapy for adverse drug reactions 降压治疗患者药物不良反应的监测
Adverse Drug Reaction Bulletin Pub Date : 2010-04-01 DOI: 10.1097/FAD.0b013e3283396c83
S. E. McDowell
{"title":"Monitoring of patients treated with antihypertensive therapy for adverse drug reactions","authors":"S. E. McDowell","doi":"10.1097/FAD.0b013e3283396c83","DOIUrl":"https://doi.org/10.1097/FAD.0b013e3283396c83","url":null,"abstract":"Many drugs, when licensed, list a requirement for monitoring during treatment. Frequently, the information is vague and the adherence of the prescriber and patient to the monitoring regimen is variable and often poor. There is a need for rational monitoring schemes that clinicians can adhere to and that protect patients.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"1003–1006"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e3283396c83","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Safety of psychotropic drug prescribed for attention-deficit/hyperactivity disorder in Italy 意大利治疗注意力缺陷/多动障碍的精神药物的安全性
Adverse Drug Reaction Bulletin Pub Date : 2010-02-01 DOI: 10.1097/FAD.0b013e3283383a63
P. Panei, R. Arcieri, M. Bonati, M. Bugarini, Anna Didoni, E. Germinario
{"title":"Safety of psychotropic drug prescribed for attention-deficit/hyperactivity disorder in Italy","authors":"P. Panei, R. Arcieri, M. Bonati, M. Bugarini, Anna Didoni, E. Germinario","doi":"10.1097/FAD.0b013e3283383a63","DOIUrl":"https://doi.org/10.1097/FAD.0b013e3283383a63","url":null,"abstract":"The drugs prescribed to treat attention-deficit/hyperactivity disorder, one of the most prevalent psychiatric disease affecting children and adolescents, may risk causing harm. Recently, the U.S. Food and Drug Administration (FDA) has warned about liver and cardiovascular risks, and the European Medicines Agency (EMEA) had performed an assessment of risk–benefit ratio of psychostimulants. Pharmacovigilance in an Italian population aged 6–17 years suggests that atomoxetine is more likely to be reported as causing harm than methylphenidate.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"999–1002"},"PeriodicalIF":0.0,"publicationDate":"2010-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e3283383a63","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Adverse effects of the volatile anaesthetics 挥发性麻醉剂的副作用
Adverse Drug Reaction Bulletin Pub Date : 2009-12-01 DOI: 10.1097/FAD.0b013e3283357c1a
E. Goble, A. Ruhnke
{"title":"Adverse effects of the volatile anaesthetics","authors":"E. Goble, A. Ruhnke","doi":"10.1097/FAD.0b013e3283357c1a","DOIUrl":"https://doi.org/10.1097/FAD.0b013e3283357c1a","url":null,"abstract":"The volatile anaesthetics are associated with a wide range of adverse effects. Alterations in cardiorespiratory function caused by the volatile anaesthetics can lead to undesirable effects. Specific anaesthetic agents have been associated with triggering emergence agitation in children and epileptiform activity. Concerns over nephrotoxicity due to metabolism of sevoflurane have proven unfounded. Hepatotoxicity occurs less frequently with the newer agents than with halothane but has still been reported. All modern agents can still trigger malignant hyperthermia.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"995–998"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e3283357c1a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse effects of anticoagulants 抗凝剂的不良反应
Adverse Drug Reaction Bulletin Pub Date : 2009-10-01 DOI: 10.1097/FAD.0b013e3283336628
Aravindan Veiraiah, P. A. Routledge
{"title":"Adverse effects of anticoagulants","authors":"Aravindan Veiraiah, P. A. Routledge","doi":"10.1097/FAD.0b013e3283336628","DOIUrl":"https://doi.org/10.1097/FAD.0b013e3283336628","url":null,"abstract":"All anticoagulant treatment increases the risk of bleeding. Warfarin causes foetal abnormalities – chrondrodysplasia punctata, and asplenia – and may increase foetal loss rate; skin necrosis and rarer adverse reactions. Unfractionated heparins can cause osteoporosis, thrombocytopenia with or without thrombosis, and other rare reactions. Low molecular weight heparins are less likely to do so.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"991–994"},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e3283336628","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Drug-induced constipation 药物引起的便秘
Adverse Drug Reaction Bulletin Pub Date : 2009-08-01 DOI: 10.1097/FAD.0b013e32833080d1
R. L. Branch, T. Butt
{"title":"Drug-induced constipation","authors":"R. L. Branch, T. Butt","doi":"10.1097/FAD.0b013e32833080d1","DOIUrl":"https://doi.org/10.1097/FAD.0b013e32833080d1","url":null,"abstract":"Constipation is a common and often debilitating adverse effect of many drugs. Here, we discuss drug classes associated with constipation, including opiates, calcium channel blockers, and anticholinergic agents, and aim to explain the underlying mechanisms involved.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"987–990"},"PeriodicalIF":0.0,"publicationDate":"2009-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e32833080d1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Statin-induced myopathy in the elderly: Part 2 老年人他汀类药物诱发的肌病:第2部分
Adverse Drug Reaction Bulletin Pub Date : 2009-06-01 DOI: 10.1097/FAD.0b013e32832c3d56
S. Chew
{"title":"Statin-induced myopathy in the elderly: Part 2","authors":"S. Chew","doi":"10.1097/FAD.0b013e32832c3d56","DOIUrl":"https://doi.org/10.1097/FAD.0b013e32832c3d56","url":null,"abstract":"Elderly patients who take statins are predisposed to statin-induced myopathy (Part 1). The associated pain and weakness can also have a significant impact on the quality of life and lead to increased morbidity by the loss of physical ability. This part deals with the difficult problem of the diagnosis and management of statin-induced myopathy in the elderly.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"&NA; 1","pages":"983–986"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e32832c3d56","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61684473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信