ABCB1 (P-glycoprotein) and the clinical pharmacology of adverse drug reactions

Q4 Medicine

Adverse Drug Reaction Bulletin Pub Date : 2010-08-01 DOI:10.1097/FAD.0b013e32833ee68a

RE Ferner

引用次数: 3

Abstract

The ABCB1 (P-glycoprotein) gene plays an important role in how drugs are metabolized, distributed and eliminated in man; these are the factors which determine whether in any particular individual a drug has an inadequate, therapeutic or toxic effect.

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ABCB1 (p -糖蛋白)与药物不良反应的临床药理学研究

ABCB1 (p -糖蛋白)基因在药物在人体内的代谢、分布和消除过程中起着重要作用;这些因素决定了一种药物对任何特定个体是否有不充分的、治疗性的或毒性的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Adverse Drug Reaction Bulletin Medicine-Pharmacology (medical)

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： For over 40 years, Adverse Drug Reaction Bulletin has provided comprehensive coverage in the field of adverse drug reactions. Each issue contains an invited article on a topic of current interest, dealing with specific conditions from drug-induced lung disorders to drug-induced sexual dysfunction, or types of drugs from lipid-lowering agents to poisons antidotes. This bimonthly journal"s articles are timely, succinct and fully referenced