Asian Journal of Medical and Biological Research最新文献

{"title":"Efficacy of dry and wet carp pituitary gland (CPG) in the induced breeding of Cyprinus carpio var. specularis (Lacepède, 1803)","authors":"B. N. Sharif, Antara Ghosh, Subrata Mondal, Mohammad Hasnal Alam, Md. Ariful Islam, Md Shamsul Kabir, M. Karim","doi":"10.3329/ajmbr.v8i2.60010","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i2.60010","url":null,"abstract":"Fish hatcheries are generally regarded as the first step in the process of aquaculture development in any given nation. Fish breeding plays an important part in the process of supplying fry and fingerling to the farmers. The current study was conducted to identify the effectiveness of using dry and wet carp pituitary gland (CPG) in the induced breeding of mirror carp (Cyprinus carpio var. specularis), at Banchte Sheka fish hatchery Arabpur, Jashore from November to December 2021. The 1st dose of hormone, both for male and female brood fishes were injected with dry & wet PG at 0.8 mg PG/kg body weight. After 6 hours of the 1st dose, only female brood fishes were injected with the 2nd dose of hormone at 3 mg PG/kg body weight. After 6-7 hours of injection of 2nd dose, brood fishes became ready to spawn. The fertilized eggs were hatched after 42-48 hours. The ovulation rates were 100%. The fertilization rates were 88.3 % and 91.2% for wet and dry PG, respectively. The hatching rates were 84.2% and 87.5%, respectively. The survival rates were 79.5% and 83.3%, respectively. Therefore, dry CPG is highly recommended to hatchery owners considering the rate of fertilization, survival rate and availability. The information that has been offered here will be helpful to the owners of hatcheries when it comes to choosing the sort of pituitary gland to use in the breeding operation.\u0000Asian J. Med. Biol. Res. 2022, 8 (2), 115-122","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129493744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicinal plants used by the tribal communities of Thanchi Upazila in Bandarban Hill District, Bangladesh","authors":"M. Alam, M. Rahman, M. K. Hossain, T. K. Ray","doi":"10.3329/ajmbr.v8i2.60336","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i2.60336","url":null,"abstract":"Medicinal plants play in an important role in the primary health care system. The paper deals with the indigenous knowledge related to ethnomedicinal knowledge and plant parts application for curing various ailments by the ethnic community of Thanchi Upazila of Bandarban Hill District. Semi-structured questionnaires, interviews, group discussions, and specific plant sample collection were done from July 2019 to December 2021 to procure ethno-medicinal data from local herbalists and elderly villagers for this study and from the forest areas. A total of 129 plant species under 110 genera and 63 families have been documented, which have been traditionally used by the ethnic people for the treatment of different ailments. Traditional knowledge and information about medicinal plants such as local names, scientific names, families, habits, habitats, plant-parts used, names of ailments, modes of use, etc. were recorded, validated, and documented. Plant families namely, Asteraceae and Euphorbiaceae were represented by the highest (8) number of species, followed by Fabaceae, Verbenaceae, Apocynaceae, Araceae, Caesalpiniaceae, Lamiaceae, Rubiaceae and Zingiberaceae. The most widely used medicinal plants included Anacardium occidentale, Bombax ceiba, Calotropis gigantea, Terminalia chebula, Aegle mermelos, Ageratum conyzoides, Andrographis paniculata, Aristolochia indica, Blumea balsamifera, Bryophyllum pinnatum, Celosia cristata, Centella asiatica, Melastoma malabathricum, Mimosa pudica, Musa paradisiaca, Oroxylum indicum, Plumbago indica and Vitex negundo. Herbs (36%) were found to be the most used plant, followed by shrubs (33%), trees (17%), climbers (9%) and fern (5%). Most medicinal plants were used for the treatment of fever, skin diseases, cough problems, menstrual problems, body pain, indigestion, headaches, stomachaches, constipation, swelling problems, wounds and others. Among the plant parts, mostly leaves were used (43%), followed by roots (21%), whole plants (10%), stems (6%) along with fruit, rhizome, flower, bark, seed and latex for the treatment of diseases. The most common formulations prescribed to treat various diseases were juices. The findings will be useful for future research in the Bandarban Hill District.\u0000Asian J. Med. Biol. Res. 2022, 8 (2), 123-140","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126710550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicinal plants available in local markets contaminated with human pathogenic bacteria - Bacillus cereus and Pseudomonas gessardii","authors":"S. M. Rokon-Ud-Doula, Nazia Afrin, M. Sikder, R. Shilpi","doi":"10.3329/ajmbr.v8i2.59510","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i2.59510","url":null,"abstract":"Medicinal plants are known to be a potential source of therapeutic aids. Different uses of medicinal plants have attained a powerful role in health system throughout the world. To study the microbial risk factor associated with medicinal plants, medicinal plant and part of plant samples (10 from each location) were collected from three different local markets (Nabinagar, Amin Bazar, and Savar) of Savar area, Dhaka, Bangladesh. A total number of fifty five (55) bacterial isolates have been isolated through their growth on Nutrient Agar media. Out of 55 isolates 31 isolates (56%) were identified as Bacillus cereus and 7 isolates (13%) were identified as Pseudomonas sp. through different morphological and biochemical tests. The CFU value of different samples revealed that all the values were higher than the accepted value (recommended by WHO, 2007) of 105 CFU/g except Phyllanthus emblica. The PCR and 16S rRNA sequencing confirmed the identification similarity values among two isolates of B. cereus and Pseudomonas gessardii. Both B. cereus and Pseudomonas gessardii showed sensitivity to the antibiotics Kanamycin, Gentamycin, Tigecycline, Ciprofloxacin and Amikacin where resistance to the antibiotics Amoxycilin, Aztreonam, Penicillin-G, Cefixime, Cefotaxime, Cefepime, Ceftriaxone, Meropenem, Cotrimoxazole and Ceftazidime. Therefore, quality assessment of herbal medicines should be ensured to make them safer for human consumption.\u0000Asian J. Med. Biol. Res. 2022, 8 (2), 69-78","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126948198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of hot water leaf and bark extract of Swietenia mahagoni against the Culex quinquefasciatus and Aedes aegypti larvae","authors":"M. Hasan, T. Akter, Md Junayed, S. Ahmad","doi":"10.3329/ajmbr.v8i2.59513","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i2.59513","url":null,"abstract":"Mosquito larvae control is essential to prevent mosquito borne diseases such as dengue, Zika, filariasis and chikungunya. Plant extract has the larvicidal properties with less toxicity to other living creatures and no resistance compared to synthetic chemical pesticides. Effect of hot water leaf and bark extract of a forest tree species (Swietenia mahagoni) against the 3rd instar larvae of Culex quinquefasciatus and Aedes aegypti was studied in vitro using five different concentrations (1-5%) of hot water leaf and bark extracts of Swietenia mahagoni. It was observed that, 5% concentrated hot water leaf extract was the most toxic killing 70% larvae of Culex quiquefasciatus and 50% larvae of Aedesa egypti after 24 hours exposure. Similarly, 5% hot water bark extracts killed 65% and 55% of Culex quiquefasciatus and Aedes aegypti larvae respectively. The minimum LC50, LC90 and LC95 values of hot water leaf extract of Swietenia mahagoni against Culex quinquefasciatus Say and Aedes aegypti (L.) with 95% confidence limits were 2.662, 6.968, 8.70 and 2.128, 4.964, 6.054 respectively after 72 hours of exposure. In hot water bark extract of Swietenia mahagoni against Culex quinquefasciatus Say and Aedes aegypti (L.) with 95% confidence limits after 72 hours of exposure minimum LC50, LC90 and LC95values were 1.780, 6.540, 9.458 and 1.370, 4.570, 6.430. The present investigation revealed the possible utilization of hot water leaf and bark extract of Swietenia mahagoni to control mosquito borne disease. Further study is needed to know the active ingredients of the leaf and bark extract of the experimented plant.\u0000Asian J. Med. Biol. Res. 2022, 8 (2), 94-102","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"22 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134292382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case-control study along with an epidemiological approach to CNTNAP2 polymorphism among Bangladeshi ASD children","authors":"Hafsa Siddiqua, Y. Akter, Md Arju Mia, Mst Sharika Ahmed, M. Chowdhury, L. Marzan","doi":"10.3329/ajmbr.v8i2.59511","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i2.59511","url":null,"abstract":"ASD (Autism Spectrum Disorder) is a neuropsychiatric disorder with a hereditary component, and its prevalence in South Asia was assessed 1, out of every 93 children. Moreover, recent studies suggested that the etiology of autism is thought to be linked to anomalies in the synapse, where mutation or deletion of synaptic gene CNTNAP2 is responsible. Therefore, this research was aimed to find out specific signs and symptoms of ASD individuals as well as the distribution pattern of the CNTNAP2 allelic variant (rs7794745) as a genetic risk factor in the Bangladeshi population. A case-control study including an epidemiological survey to investigate the association and pathophysiology of CNTNAP2 (rs7794745) with ASD for the Bangladeshi population has been studied, where PCR-RFLP analysis and Sanger sequencing were used for 180 individuals (90 ASD samples and 90 healthy controls). Our retrieved data speculated a diverse clinical profile of ASD, in comparison to the control group (n=110); where 80.9% (p ≤0.001) of ASD patients (n =100) had severe social interaction difficulties, 50% (p ≤0.001) had language impairments, and 40.9% (p ≤0.001) had behavioral abnormalities. Furthermore, findings from Pearson’s chi-square test (p = 0.001) as well as logistic regression analysis of co-dominant (p = 0.0083), and recessive model (p = 0.0075) confirmed significant association between rs7794745 and in our studied sample. This research demonstrates the genetic variation of CNTNAP2 found in our studied population could open a new clue to identifying a reliable biomarker for early diagnosis of ASD though it is recommended that more study is needed with a larger group population.\u0000Asian J. Med. Biol. Res. 2022, 8 (2), 79-93","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123442186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and radiological characteristics of adult hospitalized coronavirus disease-2019 patients of Dhaka, Bangladesh","authors":"A. Suman, Khadija Begum, K. Rahman, Saifullah Khan, Mohammad Morshad Alam","doi":"10.3329/ajmbr.v8i1.58931","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i1.58931","url":null,"abstract":"The severity of Coronavirus disease-2019 (COVID-19) varies among individuals and some influential factors leads to critical infections and death. This study aimed to assess various clinical data of hospitalized patients and identify the determinants of critical COVID-19 infection. This was a cross-sectional study among hospitalized COVID-19 patients confirmed by reverse transcription polymerase chain reaction (RT-PCR). Data was collected from a single Centre between January to April 2021 by experienced physicians of Ad-din Medical College Hospital. All of the laboratory tests were performed by technical experts and the data was analyzed by Statistical package for the social sciences software. Among the study participants 25% were Intensive care unit (ICU) patients and the mean age of them were higher (59 years) than non-ICU (55 years) patients. Our analysis has identified diabetes mellitus (AOR=2.5, 95%CI: 1.1-5.4) and ischemic heart disease (AOR=3.1, 95%CI: 1.1-8.9) as significant predictor of critical outcome (ICU admission). Anemia (AOR=3.3, 95%CI: 1.5-7.4), lymphopenia (AOR=2.9, 95%CI: 1.2-7.1), and thrombocytopenia (AOR=4.2, 95%CI: 2.7-12.9) was also associated critical outcome. Biomarkers of kidney injury (creatinine, blood urea nitrogen), liver damage (alanine transaminase, aspartate aminotransferase, fibrinogen) and electrolyte imbalance (sodium and potassium level) were also significantly associated with critical infection. A higher d-dimer level (≥2.5) was the most important predictor (AOR=11.5, 95%CI: 5.4-24.6) of critical COVID 19 infections. The study has revealed socio-demographic, comorbidity, and radiological risk factors of critical COVID-19 infections. The identified risk factors would be considered for decision making during the treatment process.\u0000Asian J. Med. Biol. Res. 2022, 8 (1), 16-23","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128717355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salmonella and Escherichia coli contamination in wild catfish and rivers at northern part of Bangladesh","authors":"M. Faridullah, Banya Rani, Md. Reazul Islam, M. Rana","doi":"10.3329/ajmbr.v8i1.58930","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i1.58930","url":null,"abstract":"A variety of fishes consumed regularly are prone to pathogenic spoilage especially by different microbes. It is important to find out microbiological quality of fish that we consume regularly to protect the public health. Current research was conducted to assess the incidence of Salmonella and Escherichia coli (E. coli) contamination in three selected catfish species namely, Ayer (Sperata seenghala), Pabda (Ompok pabda) and Magur (Clarias batrachus) of five rivers (Dhepa, Atrai, Punorvoba, Kakra, and Ghorveshori) of Dinajpur district. The study showed that Salmonella and E. coli positive isolates were 33.33% and 55.55% in Punorvoba river, 31.03% and 50.00% in Atrai river, 30.19% and 56.60% in Dhepa river, 29.63% and 59.26% in Ghorveshori river and 27.08% and 56.25% in Kakra river, respectively. Highest percentage of Salmonella and E. coli were found in Ompok pabda (39.40%) and in Clarias batrachus (63.84%), respectively. Lowest percentage of Salmonella and E. coli were found in Sperata seenghala (26.50% and 41.07%), respectively. The percentage of E. coli was greater than Salmonella for each of the experimental samples that are very alarming for consumption of wild catfish. At the same time, the microbial quality of water of Dhepa, Atrai, Punorvoba, Kakra, and Ghorveshori rivers are not satisfactory regarding fish consumption and public health.\u0000Asian J. Med. Biol. Res. 2022, 8 (1), 9-15","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126607301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of flock immunity against Newcastle disease in native chicken in a locality","authors":"S. Akther, Md. Zakir Hassan","doi":"10.3329/ajmbr.v8i1.58934","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i1.58934","url":null,"abstract":"Preventive measures to combat with Newcastle disease virus (NDV) can be achieved by vaccination programs that are practiced in many countries of the world. Even after vaccination outbreaks of NDV occurred in the flock indicate that vaccination against NDV cannot provide effective immunity that may cause disease in partially vaccinated flock. Hence, the objectives of this study was to development of flock immunity in chicken against Newcastle disease in a local community. In this study a vaccination programme for the native flock in a locality (Dhamrai, Savar, Dhaka, Bangladesh) was conducted and effectiveness of the Ranikhet disease vaccine (RDV) was identified with detection of antibody titers that may protect the native flocks against the disease but mortality or the infection was present. The study showed that after routine vaccination with BCRDV (Baby Chicks Ranikhet Disease Vaccine) and RDV (Ranikhet Disease Vaccine) vaccine the native chicken showed high antibody titre in native chicken. Overall herd immunity of native chickens can be achieved if the maximum (>80%) chicken obtains high antibody titers (log2 haemagglutination inhibition titer ≥3) after vaccinations. So, it can be concluded that successful vaccinations programme is the key point to control NDV with higher herd health immunity.\u0000Asian J. Med. Biol. Res. 2022, 8 (1), 37-41","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133891685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy diagnosis in goats (Capra hircus) using barium chloride and progesterone-based kit in Bangladesh","authors":"S. Akther, Md. Nuruzzaman Munsi, Md. Habibur Rahman, Md. Zakir Hassan","doi":"10.3329/ajmbr.v8i1.58935","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i1.58935","url":null,"abstract":"The study was conducted to develop a technique for early diagnosis of pregnancy in goats from July 2016 to June 2017. About 100 goats of different age groups were randomly selected for the trial and goats were categorized under four groups according to their gestation lengths (0.5 to 1 month, >1 to 1.5 months, >1.5 to 2 months and >2 to 2.5 months). Blood from jugular vein and morning urine samples were collected from four groups and brought to the laboratory, and serum was separated from the clotted blood. Then 1%, 1.5% and 2% barium chloride solution were prepared and test was done by using 1 ml barium chloride of each concentration mixing with 1 ml of urine sample, and allowed for 5 and 10 minutes for interpretation. Presence of precipitation was interpreted as negative for pregnancy and absence of precipitation was interpreted as positive for pregnancy. For each blood sample, 3-5 drops of serum was added in each sample insertion hole of the Bovipreg kit and 5 minutes was allowed to observe the presence of one or two red line in the kit. One red line was interpreted as negative pregnancy and two red lines were interpreted as positive pregnancy. In our study 1% barium chloride, showed 93.5% accuracy, whereas 1.5% barium chloride provided 92% accuracy for the goats having 0.5 to 1 month of gestation. In case of 2% barium chloride, the highest accuracy was 91.5% for the goats having >1 to 1.5 month of gestation. Conversely, the accuracy for progesterone-based early pregnancy diagnostic kit was 96.5%. Therefore, 1% barium chloride can be utilized for the diagnosis of pregnancy in goats.\u0000Asian J. Med. Biol. Res. 2022, 8 (1), 42-46","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124004804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular detection of foot and mouth disease virus serotype A in goats (Capra hircus)","authors":"Md. Habibur Rahman, S. Akther, Md. Zakir Hassan, Md. Zulfekar Ali, M. Giasuddin","doi":"10.3329/ajmbr.v8i1.58933","DOIUrl":"https://doi.org/10.3329/ajmbr.v8i1.58933","url":null,"abstract":"Foot and mouth disease (FMD) is a highly contagious, transboundary, and re-emerging viral disease that mostly affects cloven-hoofed animals specially cattle, goats, swine, sheep, etc. resulting in significant economic losses. Despite regular vaccination, outbreaks of the disease have become a yearly occurrence across the country. RT-PCR was used to determine the prevalence and molecular detection of serotype A of FMDV in clinically affected goats in Goat research farm, BLRI, Savar, Dhaka, Bangladesh during August 2018. A total of 9 samples were taken from 1 to 2 years old Black Bengal goats suspected to have FMD. FMDV was detected in 55.56% (5/9) of the suspected samples using RT-PCR. The serotype of positive samples was also determined using gsRT-PCR. However, FMDV serotype A was prevalent in 100% (5) positive samples. Additionally, considering the age, the prevalence of confirmed FMD outbreak was 40% (2), 40% (2), and 20% (1) at the age of 1, 1.5 and 2 years, respectively. It was found that young goats are more susceptible to FMDV than adults. However, it can be concluded that suspected goats were infected with FMDV serotype A and trivalent FMD vaccine is suggested for prevention and control of FMD outbreak.\u0000Asian J. Med. Biol. Res. 2022, 8 (1), 30-36","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122047299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}