Asian Journal of Medical and Biological Research最新文献

{"title":"Effects of different orthodontic appliances on Actinomyces spp.","authors":"Aybuke Asena Atasever Isler, Abdulvahit Erdem","doi":"10.3329/ajmbr.v10i1.70292","DOIUrl":"https://doi.org/10.3329/ajmbr.v10i1.70292","url":null,"abstract":"This study aims to identify the presence of Actinomyces species in the oral flora during orthodontic treatments using removable appliances and fixed wire technique, and to track changes throughout the treatment process. In this study, subgingival and supragingival plaque samples obtained from 48 patients undergoing orthodontic treatment at a dental facilities of Ataturk University, Türkiye were utilized as the primary material. The study groups comprised individuals undergoing fixed orthodontic treatment, those using removable appliances, and individuals who had not undergone any orthodontic treatment. Plaque samples were collected from the patients at the initiation of treatment and six months thereafter. After selective culturing in a specific medium, dental plaque samples were purified and subjected to microbial analysis using the VITEK 2 system (Biomerieux). The study aimed to identify and compare the microbial content of plaque samples from different orthodontic treatment groups. Actinomyces species were identified in all groups at both the initiation of treatment (T0) and six months later (T1) periods. At the beginning of treatment, Actinomyces species were found in 33 samples, while at six months, they were present in 18 samples. The curent study revealed similar microorganisms among the groups at both T0 and T1 periods. The Actinomyces species identified in this study include Actinomyces meyeri, Actinomyces naeslundii, and Actinomyces odontolyticus. It is evident that orthodontic treatments significantly impact oral health and that Actinomyces microorganisms are always likely to be present in the oral flora.\u0000Asian J. Med. Biol. Res. 2024, 10(1), 1-8","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"39 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139536673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Industrial enzyme production in Bangladesh: current landscape, scope, and challenges","authors":"Imam Hossain, Israt Jahan Mitu, Md Rakibul Hasan, Sumita Rani Saha","doi":"10.3329/ajmbr.v9i4.69395","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i4.69395","url":null,"abstract":"Enzymes are important biological catalysts that perform specialized functions within living organisms. Industrial enzymes are crucial in various sectors, including pharmaceuticals, the textile industry, the manufacturing of chemicals, biodiesel, the food and beverages industry, and consumer goods. Enzymes can be obtained from multiple sources, including microbes, animals, and plants.  Microorganisms, especially bacteria and fungi, provide more than 50% of industrial enzymes because of their advantageous growth features, low nutritional needs, and biochemical diversity.  Bangladesh's economy relies heavily on agriculture and generates biomass energy from waste such as rice husk, straw, jute sticks, and sugarcane bagasse. To reduce the environmental impact, it is vital to modify these waste materials into beneficial industrial and commercial products, like enzymes. This review article investigates the current landscape, scope, and challenges of industrial enzyme production in Bangladesh. Bangladesh has become an appealing destination for biotech firms due to variables such as yearly bio-product imports, local market consumer demand, and the availability of resources and competent people. In 2021, Bangladesh ranked as the 34th largest importer of enzymes worldwide, with an import value of $47.4 million. Bangladesh mainly imports enzymes from Turkey, Malaysia, China, Singapore, and Sri Lanka. This study identifies a critical research gap, which is the lack of a dedicated industrial enzyme production industry in Bangladesh. This gap is impeding large-scale implementation, despite ongoing research efforts. Furthermore, we suggest the establishment of a specialized industrial enzyme production sector in Bangladesh, which would benefit the environment and promote economic growth through the utilization of agro-industrial waste resources. Finally, this thorough assessment of current industrial enzyme research in Bangladesh seeks to provide researchers and stakeholders with essential information for future development. Collaboration between the government, businesses, and academics is critical to fostering growth and capitalizing on the potential of the worldwide enzyme industry.\u0000Asian J. Med. Biol. Res. 2023, 9 (4), 145-159","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138972509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-socio-economic analysis of ESBN fishery of Kattoli coastal area of Chattogram, Bangladesh","authors":"Md. Atiqul Islam Mondal, Anwar Hossain Choudhury, A. Siddiqui, Md Rashed-Un-Nabi, MA Kader","doi":"10.3329/ajmbr.v9i4.68610","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i4.68610","url":null,"abstract":"In consideration of the characteristics inherent to the estuarine ecosystem, the employment of the estuarine set bag net (ESBN) emerges as an effective instrument for the capture of a diverse spectrum of finfish and shellfish species. The present investigation, conducted between May and December 2015 in Kattoli, a representative locality along the Chattogram coast, was undertaken to perform a comprehensive bio-socio-economic analysis of the ESBN fishery. The analysis of the catch composition in Kattoli revealed that finfish constituted 67.67%, shrimp accounted for 24.34%, and crab made up 7.99% of the total catch. The average daily catch per boat in Kattoli was determined to be 25.8 kg. The zenith of the total daily catch per boat, reaching 70 kg, was observed in December, while the nadir occurred in August, when no fishing activities were recorded in Kattoli. The cumulative catch over the study period in Kattoli amounted to 26,664 kg, with a complete absence of fishing in August. Moreover, the average daily catch per fisherman stood at 6.19 kg in Kattoli. In terms of economic considerations, the mean monthly cost per boat in the Kattoli region was approximately 8,750 BDT, while the average monthly sales revenue exceeded 28,695 BDT in Kattoli. Notably, during July and August, a substantial proportion of fishermen were engaged in Hilsa (Tenualosa ilisha) fishing utilizing gill nets, which resulted in a diminished catch with ESBN during these months. Furthermore, the preliminary socio-economic conditions of the study area were also explored. This research offers valuable insights into the bio-socio-economic dimensions of the ESBN fishery in the Kattoli coastal area, with potential practical implications for fisheries management and the livelihoods of the local fishing community. Asian J. Med. Biol. Res. 2023, 9 (4), 114-125","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"5 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139243266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of alopecia among patients attended in dermatology clinic of Dhaka city: role of socio-demographic and clinical profiles on treatment process","authors":"M. Rahaman, Anzirun Nahar Asma, A. Siddiqua, R. U. Siddique, Sabrina Akter, Morshad Alam","doi":"10.3329/ajmbr.v9i4.66801","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i4.66801","url":null,"abstract":"The treatment of alopecia is widely available, and numerous studies have been conducted for its improvement. However, research focusing on the Bangladeshi population is extremely rare. A number of dermatology clinics in Bangladesh are providing advanced treatment; therefore, the efficacy of those treatments needs to be assessed. The aim of this study was to determine the pattern of alopecia in Bangladesh and identify the factors that are associated with poor treatment responses to administered therapies. We conducted a cross-sectional study among alopecia patients who were getting treatment at Aurora Skin and Aesthetics and completed at least six sessions under an experienced physician. Interviews run by experienced physicians collected demographic, clinical, treatment, and comorbidity-related information from patients aged between 18 and 65 years. The collected data were analyzed using STATA (version 16.0). Among our participants, male pattern baldness (stage-2) was most common (43.6%), followed by male pattern baldness (stage-3) (18.8%) and female pattern hair loss (FPHL), stage-2 (13.9%). The treatment efficacy was good for 46.5% of patients, medium for another 42.56%, and only 10.9% showed poor efficacy. The oily hair of participants showed a statistically significant negative association with treatment efficacy (P=0.018). The presence of chronic disease and stress among alopecia patients also negatively impacts the treatment process (P<0.05). Smoking among alopecia patients also hampers the treatment process and is significantly associated with poor treatment efficacy. From this study, it is clear that the ongoing treatment has overall excellent efficacy; however, attention should be given to the comorbidities and habits of patients to improve the treatment outcome. The findings of this study would help skin specialists make decisions during alopecia treatment. Asian J. Med. Biol. Res. 2023, 9 (4), 106-113","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139316724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinico-demographic and microbiological profile of acute pyelonephritis in Azadi Teaching Hospital, Duhok province, Iraqi Kurdistan","authors":"Sagvan Kareem Taha, K. H. Abd, Fatima Nawaf Abdulkareem, Z. S. M. Saleem, Safa EizAldein Almukhtar, Muayad A Merza","doi":"10.3329/ajmbr.v9i3.66388","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i3.66388","url":null,"abstract":"The aims of this study were to identify the demographic and clinical characteristics of community associated acute pyelonephritis (CA-APN) or healthcare associated APN (HCA-APN), to determine risk factors linked with APN, and to identify the microbiological profile and its susceptibility patterns to antibiotics. A cross-sectional study was conducted from September to November 2022 at the nephrology unit of Azadi Teaching Hospital, Duhok, Iraqi Kurdistan. Urine and blood samples were collected from patients diagnosed with APN. These samples were investigated to identify the microbiologic profile of the infecting organisms and determine their antibiotic susceptibility results. From a total of 97 adult and elderly APN patients, 55 (56.7%) were classified as HCA-APN, while 42 (43.3%) were classified as CA-APN. In the univariate analysis, age ≥ 65, catheterization, chronic kidney disease, hemodialysis, diabetes mellitus (DM), cardiovascular disease (CVD), neurologic disease, chronic pulmonary disease, PCT level, and ANC were identified as significant risk factors for HCA-APN compared to CA-APN. Patients with catheterization and CVD history showed independent association in the multivariate analysis. The overall mortality rate was 11.3%, which was significantly associated with HCA-APN (P = 0.002). Considering the microbiological profile, Escherichia coli uropathogen (n=61) was the predominant isolated bacteria followed by Klebsiella pneumoniae (n=17). High antibiotic resistance rates were observed in fluoroquinolones and third generation cephalosporin classes among E. coli uropathogen in both CA-APN and HCA-APN patients, with a rate of 74.5 % and 63.9%, respectively. In conclusion, there is an increase in mortality rate regarding HCA-APN. The HCA-APN characteristics should be considered when prescribing empiric antibiotics. In our local setting, carbapenems are effective empiric therapies against enterobacteraceae uropathogens, for both HCA-APN and CA-APN. In order to prevent the emergence and spread of antibiotic resistance, implementing surveillance systems, infection prevention and control measures, and antimicrobial stewardship programs within our healthcare setting is crucial. Asian J. Med. Biol. Res. 2023, 9 (3), 59-69","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139358060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An overview of climate-driven stress responses in striped catfish (Pangasianodon hypophthalmus) – prospects in aquaculture","authors":"Meftahul Zannat, Farzana Hossain, Umme Ohida Rahman, Md Fazle Rohani, Md Shahjahan","doi":"10.3329/ajmbr.v9i3.66474","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i3.66474","url":null,"abstract":"Aquaculture sector significantly contribute in terms of food and nutrition security, sustainable livelihood, poverty eradication as well as overall economic development throughout the world. However, sustainable aquaculture production is a great challenge due to the climate change issues including global warming, rainfall variation, flood, and salinity intrusion. To consider the negative effects of climate changes on aquaculture production, culture of striped catfish can be one of the effective strategies for adaptation to climate changes. The capability to tolerate several adverse environmental conditions makes it a suitable aquaculture species. Moreover, striped catfish can be cultured at high stocking densities in wide range of waterbodies such freshwater, brackish water and saltwater environment as well as culture practices including monoculture, polyculture, and cage culture. Finally, it is highly recommended that striped catfish could be the best suitable candidate for aquaculture to adapt the future climate changes. Asian J. Med. Biol. Res. 2023, 9 (3), 70-88","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139357898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The treatment efficacy of vitiligo patients attending in a dermatology clinic: an impact of clinico-epidemiological profiles and co-morbidities","authors":"M. Rahaman, Anzirun Nahar Asma, A. Siddiqua, Sabrina Akter, R. U. Siddique, Morshad Alam","doi":"10.3329/ajmbr.v9i2.65763","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i2.65763","url":null,"abstract":"There is widespread misinformation, taboos, and a lack of scientific analysis about vitiligo. In Bangladesh, there is a scarcity of research on vitiligo, though advanced treatments are widely available. This study aimed to investigate the treatment efficacy of vitiligo in a selected dermatology clinic and analyze the factors that impact the efficacy level. This was an analytical cross-sectional study among vitiligo patients who attended a dermatology clinic for treatment and were followed up for at least six months. Patients were treated by experienced physicians through a holistic treatment approach. An interviewer-administered questionnaire was used to collect information after obtaining informed consent. The data was processed by Microsoft Excel 2013 and analyzed by SPSS 25.0. The mean age of the study participants was 25.14 ± 13.32 years, where 60% were female. Acrofacial (33%), focal (27%), and acral (14%) are the most common types of vitiligo, and the face (n=73) is the most common body part. We have seen excellent treatment efficacy as proven by 94% of patients' lesion sizes decreased and 96% gained repigmentation at six months' follow-up. Our study revealed there is a negative impact of the presence of systemic disease and co-morbidities on vitiligo. The efficacy of the treatment was significantly affected by advanced age, body surface area, hypertension, diabetes, and anemia (P<0.05). Our analysis revealed a good treatment efficacy of holistic treatment for vitiligo in selected clinic. For more effective treatment, control of co-morbidities is essential. The findings of this study will help clinicians in their decision making during the treatment process of vitiligo.\u0000Asian J. Med. Biol. Res. 2023, 9 (2), 51-58","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"215 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133937330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of campylobacteriosis in Bangladesh: challenges and opportunities","authors":"S. S. Islam, N. Hoque, A. Akhter, D. Castellan, S. Samosornsuk, W. Samosornsuk, S. Kabir","doi":"10.3329/ajmbr.v9i2.66775","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i2.66775","url":null,"abstract":"Campylobacter is a prevalent zoonotic bacterial pathogen found in various food animals such as cattle, sheep, goats, and poultry. The increasing production of crossbred cattle in Bangladesh is aimed at meeting the demand for animal protein. However, this trend also poses public health risks associated with emergence of cattle-specific Campylobacter. It is probable that there is an increased probability of transmission of pathogenic Campylobacter among humans and animals, as well as within the farm environment. Nevertheless, it has been established that Campylobacter is also a significant contributor to childhood diarrhea in Bangladesh.  The objective of this study is to examine Campylobacter in animals and humans, including the risk factors that contribute to its occurrence, patterns of antimicrobial resistance, and measures that can be taken to prevent and control its spread. The study has established predominant maintenance zoonotic Campylobacter in source animals and their burden in humans is enormous. Our research is primarily focused on promoting public health by improving cleaning and sanitation practices in animal farms, which can help reduce the amount of Campylobacter present in the environment. The data and insights provided in this article can be valuable for policy planners and public health experts who are working to create effective and sustainable strategies aimed at reducing the risks associated with Campylobacter infection over the long term.\u0000Asian J. Med. Biol. Res. 2023, 9 (2), 38-50","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125517723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Productive and reproductive performance of indigenous buffaloes in four selected upazillas under Mymensingh district of Bangladesh","authors":"M. R. Karim, R. Habib, Mohammad Imam Hossain, A. Wadud","doi":"10.3329/ajmbr.v9i2.65519","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i2.65519","url":null,"abstract":"The present study aimed to examine the productive and reproductive performance of Indigenous buffaloes in the Mymensingh district of Bangladesh. Buffalo husbandry plays a crucial role in the livelihoods of numerous farmers across various upazilas in Mymensingh. A total of 100 indigenous buffaloes were selected for the study, representing four upazilas: Trishal, Haluaghat, Muktagachha, and Sadar upazilla in Mymensingh district. The findings of this study revealed that the average lactation length of indigenous buffaloes was 273.04±4.75 days. Furthermore, the average milk yield of indigenous buffaloes was measured at 2.33±0.77 litres. The average birth weight, gestation period, age at first calving, calving interval, and post-partum heat period for indigenous buffaloes were observed to be 19.44±3.24 kg, 313.04±6.40 days, 52.53±3.10 months, 558.43±60.05 days, and 142.33±29.32 days, respectively. Based on the results obtained from all the parameters studied, it can be concluded that the productive and reproductive performance of Indigenous buffaloes in the Trishal upazilla surpassed that of the other three upazilas.\u0000Asian J. Med. Biol. Res. 2023, 9 (2), 30-37","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132907433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacts of food and habitat on blood profile of rohu Labeo rohita (Hamilton, 1822)","authors":"Saad Abu Wakkas, Md Iqramul Haque, Mohammad Ashaf-Ud-Doulah, Muhammed Shahjahan","doi":"10.3329/ajmbr.v9i2.65041","DOIUrl":"https://doi.org/10.3329/ajmbr.v9i2.65041","url":null,"abstract":"Food and habitat are important environmental factors, which are play significant role in the physiology of fish. The present experiment was conducted to ascertain the effects of food and habitat on hematological parameters in rohu Labeo rohita reared from first feeding in pond with natural foods and in aquarium using formulated feed for three months (90 days). Fish were sacrificed after the rearing period and hemato-biochemical parameters (hemoglobin - Hb, red blood cell - RBC, white blood cell - WBC and glucose) were measured. Hb (%) of the fish in ponds was slightly higher than in the fish of aquarium. RBC (×106/mm3) in the fish reared in aquaria showed a significant decline in comparison to the pond reared fish, whereas WBC (×103/mm3) showed opposite scenario. Blood glucose was slightly higher in the fish of aquarium than in the fish of pond. The water quality parameters showed no significant difference between the two habitats. The data reported in this study contributes towards the knowledge of hematological evaluation in Labeo rohita and showed that fish food and habitat were crucial in establishing the physiological range supporting the accurate interpretation of hematological parameters for use in examining the health status of this species.\u0000Asian J. Med. Biol. Res. 2023, 9 (2), 23-29","PeriodicalId":391187,"journal":{"name":"Asian Journal of Medical and Biological Research","volume":"68 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130877998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}