某地土鸡新城疫群体免疫的建立

S. Akther, Md. Zakir Hassan
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摘要

对抗新城疫病毒(NDV)的预防措施可以通过世界上许多国家实行的疫苗接种计划来实现。即使在接种疫苗后,在鸡群中也发生了新城疫暴发,这表明针对新城疫的疫苗接种不能提供有效的免疫,可能会在部分接种疫苗的鸡群中引起疾病。因此,本研究的目的是在当地社区发展鸡对新城疫的群体免疫。在这项研究中,对一个地方(孟加拉国达卡的Dhamrai、Savar、Dhamrai)的本地鸡群进行了疫苗接种规划,并通过检测抗体滴度确定了Ranikhet病疫苗(RDV)的有效性,该疫苗可能保护本地鸡群免受疾病的侵害,但存在死亡或感染。研究表明,在常规接种雏鸡拉涅赫特病疫苗(BCRDV)和拉涅赫特病疫苗(RDV)后,本地鸡在本地鸡中显示出较高的抗体滴度。如果接种后最大(bbb80 %)鸡获得高抗体滴度(log2血凝抑制滴度≥3),则可实现地方鸡的整体群体免疫。因此,成功的疫苗接种规划是控制新城疫的关键,具有较高的群体健康免疫力。亚洲医学杂志。Res. 2022, 8 (1), 37-41
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Development of flock immunity against Newcastle disease in native chicken in a locality
Preventive measures to combat with Newcastle disease virus (NDV) can be achieved by vaccination programs that are practiced in many countries of the world. Even after vaccination outbreaks of NDV occurred in the flock indicate that vaccination against NDV cannot provide effective immunity that may cause disease in partially vaccinated flock. Hence, the objectives of this study was to development of flock immunity in chicken against Newcastle disease in a local community. In this study a vaccination programme for the native flock in a locality (Dhamrai, Savar, Dhaka, Bangladesh) was conducted and effectiveness of the Ranikhet disease vaccine (RDV) was identified with detection of antibody titers that may protect the native flocks against the disease but mortality or the infection was present. The study showed that after routine vaccination with BCRDV (Baby Chicks Ranikhet Disease Vaccine) and RDV (Ranikhet Disease Vaccine) vaccine the native chicken showed high antibody titre in native chicken. Overall herd immunity of native chickens can be achieved if the maximum (>80%) chicken obtains high antibody titers (log2 haemagglutination inhibition titer ≥3) after vaccinations. So, it can be concluded that successful vaccinations programme is the key point to control NDV with higher herd health immunity. Asian J. Med. Biol. Res. 2022, 8 (1), 37-41
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