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Cellular Therapy and Transplantation最新文献

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Exosomes as a promising tool for research and molecular diagnostics of myeloproliferative disorders 外泌体作为骨髓增生性疾病研究和分子诊断的一个有前途的工具
Cellular Therapy and Transplantation Pub Date : 2019-06-28 DOI: 10.18620/ctt-1866-8836-2019-8-2-74-81
Anna Parfenenkova, I. Barkhatov, A. Kremlev, Olga A. Epifanovskaya, A. Gorshkov, V. Vysochinskaya, M. Grudinin, A. A. Kornev, B. Afanasyev
{"title":"Exosomes as a promising tool for research and molecular diagnostics of myeloproliferative disorders","authors":"Anna Parfenenkova, I. Barkhatov, A. Kremlev, Olga A. Epifanovskaya, A. Gorshkov, V. Vysochinskaya, M. Grudinin, A. A. Kornev, B. Afanasyev","doi":"10.18620/ctt-1866-8836-2019-8-2-74-81","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2019-8-2-74-81","url":null,"abstract":"CTT JOURNAL | VOLUME 8 | NUMBER 2 | JUNE-JULY 2019 Anna N. Parfenenkova 1, Ildar M. Barkhatov 2, Anton A. Kremlev 2, Olga A. Epifanovskaya 2, Andrey N. Gorshkov 3, Vera V. Vysochinskaya 3, Mikhail P. Grudinin 3, Anton A. Kornev 4, Boris V. Afanasyev 2 1 St. Petersburg State University of Chemical Pharmaceutics, St. Petersburg, Russia 2 Raisa Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia 3 A. Smorodintsev Research Institute of Influenza, St. Petersburg, Russia 4 St. Petersburg National Research University, Russian Academy of Sciences, St. Petersburg, Russia Exosomes as a promising tool for research and molecular diagnostics of myeloproliferative disorders Cellular Therapy and Transplantation (CTT). Vol. 8, No. 2, 2019 doi: 10.18620/ctt-1866-8836-2019-8-2-74-81 Submitted: 20 May 2019, accepted: 26 July 2019","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77432384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Experimental urinary bladder reconstruction using allogeneic tissue engineering products 异体组织工程产品实验性膀胱重建
Cellular Therapy and Transplantation Pub Date : 2019-06-28 DOI: 10.18620/ctt-1866-8836-2019-8-2-68-73
N. V. Orlova, A. Muraviov, T. I. Vinogradova, N. M. Yudintceva, Y. Nashchekina, N. V. Zabolotnih, A. Lebedev, Magomedsadik G. Sheykhov, P. Yablonsky
{"title":"Experimental urinary bladder reconstruction using allogeneic tissue engineering products","authors":"N. V. Orlova, A. Muraviov, T. I. Vinogradova, N. M. Yudintceva, Y. Nashchekina, N. V. Zabolotnih, A. Lebedev, Magomedsadik G. Sheykhov, P. Yablonsky","doi":"10.18620/ctt-1866-8836-2019-8-2-68-73","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2019-8-2-68-73","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72700487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical significance of BAALC overexpression for predicting post-transplant relapses in acute myeloid leukemia BAALC过表达预测急性髓系白血病移植后复发的临床意义
Cellular Therapy and Transplantation Pub Date : 2019-06-28 DOI: 10.18620/ctt-1866-8836-2019-8-2-45-57
A. Shakirova, N. Mamaev, I. Barkhatov, Y. V. Gudozhnikova, T. Gindina, E. Babenko, B. Afanasyev
{"title":"Clinical significance of BAALC overexpression for predicting post-transplant relapses in acute myeloid leukemia","authors":"A. Shakirova, N. Mamaev, I. Barkhatov, Y. V. Gudozhnikova, T. Gindina, E. Babenko, B. Afanasyev","doi":"10.18620/ctt-1866-8836-2019-8-2-45-57","DOIUrl":"https://doi.org/10.18620/ctt-1866-8836-2019-8-2-45-57","url":null,"abstract":"Alena I. Shakirova, Nikolay N. Mamaev, Ildar M. Barkhatov, Yana V. Gudozhnikova, Tatiana L. Gindina, Elena V. Babenko, Boris V. Afanasyev Raisa Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia Clinical significance of BAALC overexpression for predicting post-transplant relapses in acute myeloid leukemia Cellular Therapy and Transplantation (CTT). Vol. 8, No. 2, 2019 doi: 10.18620/ctt-1866-8836-2019-8-2-45-57 Submitted: 08 May 2019, accepted: 28 June 2019","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89729304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Application of standard and novel prognostic systems in patients with myelodys- plastic syndrome undergoing allogeneic hematopoietic stem cell transplantation 标准和新型预后系统在异基因造血干细胞移植骨髓增生综合征患者中的应用
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-36-45
E. Morozova, M. Barabanshikova, Nikolai Y. Tcvetkov, Ksenia V. Melsitova, Julia V. Rudnitskaya, E. I. Darskaya, S. Bondarenko, I. Moiseev, B. Afanasyev
{"title":"Application of standard and novel prognostic systems in patients with myelodys- plastic syndrome undergoing allogeneic hematopoietic stem cell transplantation","authors":"E. Morozova, M. Barabanshikova, Nikolai Y. Tcvetkov, Ksenia V. Melsitova, Julia V. Rudnitskaya, E. I. Darskaya, S. Bondarenko, I. Moiseev, B. Afanasyev","doi":"10.18620/CTT-1866-8836-2019-8-1-36-45","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-36-45","url":null,"abstract":"Elena V. Morozova, Maria V. Barabanshikova, Nikolai Yu. Tcvetkov, Ksenia V. Melsitova, Julia V. Rudnitskaya, Elena I. Darskaya, Sergey N. Bondarenko, Ivan S. Moiseev, Boris V. Afanasyev R. Gorbacheva Memorial Research Institute for Pediatric Oncology, Hematology and Transplantation, The First Pavlov St. Petersburg State Medical University, St. Petersburg, Russian Federation Application of standard and novel prognostic systems in patients with myelodysplastic syndrome undergoing allogeneic hematopoietic stem cell transplantation Cellular Therapy and Transplantation (CTT). Vol. 8, No. 1, 2019 doi: 10.18620/ctt-1866-8836-2019-8-1-36-45 Submitted: 06 March 2019, accepted: 15 March 2019","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88577505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Drug repurposing in leukemia treatment and hematopoietic stem cell transplantation 白血病治疗和造血干细胞移植中的药物再利用
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-12-19
A. Chukhlovin
{"title":"Drug repurposing in leukemia treatment and hematopoietic stem cell transplantation","authors":"A. Chukhlovin","doi":"10.18620/CTT-1866-8836-2019-8-1-12-19","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-12-19","url":null,"abstract":"Over last decade, a number of studies has concerned possible implications of “old” medical drugs, as additional tools for cancer treatment. The main reasons for extension of drug indications are as follows: (1) limited efficiency or high costs of targeted oncogene protein inhibitors or specific monoclonal antibodies for therapy; (2) new molecular targets were revealed for some drugs traditionally used to other therapeutic purposes; and (3) sufficient decline of development costs for the new therapies performed by the “old” drugs. The list of such repurposed drugs now includes dozens of medications commonly used for treatment of cardiovascular diseases, diabetes mellitus, epilepsia, different inflammatory disorders. The present review deals, mainly, repurposing of anti-infectious drugs, including those used in prevention and management of infectious complications occurring in cytostatic therapy of leukemia and lymphomas, e.g., tetracyclines, erythromycin derivatives, as well as fluoroquinolones, antiviral compounds etc. The antitumor effects were of these candidates for repurposing were demonstrated upon screening of their cytostatic effects in leukemic and other cancer cell lines. Some studies were performed in experimental tumor-bearing animals. Only few clinical trials were carried out in patients with leukemias and lymphomas following hematopoietic stem cell transplantation (HSCT), which showed some positive effects of antibacterial drugs in terms of graft-versus-host disease (GvHD) prevention, or prolonged survival of the patients. Controlled clinical trials of common anti-infectious drugs are required for this repurposing.","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90202387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A clinical case of familial hemophagocytic lymphohistiocytosis 家族性噬血细胞淋巴组织细胞病1例
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-54-57
T. Bykova, V. Ovechkina, A. Osipova, A. Kozlov, A. Alyanskiy, E. Semenova, L. Zubarovskaya, B. Afanasyev
{"title":"A clinical case of familial hemophagocytic lymphohistiocytosis","authors":"T. Bykova, V. Ovechkina, A. Osipova, A. Kozlov, A. Alyanskiy, E. Semenova, L. Zubarovskaya, B. Afanasyev","doi":"10.18620/CTT-1866-8836-2019-8-1-54-57","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-54-57","url":null,"abstract":"","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90299599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternative approaches to overcome diastasis of damaged peripheral nerves. A review article 替代方法克服受损周围神经转移。一篇综述文章
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-20-25
O. Galibin, G. V. Medvedev, P. Popryadukhin, P. A. Kulagin, A. Gusev, Galina P. Kossyakova, N. Mikhailova, V. D. Novak, D. N. Solomitskiy, I. O. Shemiakin, V. Gadzhiagaev, M. K. Gurbannazarov, St. Petersburg Russia Orthopedy
{"title":"Alternative approaches to overcome diastasis of damaged peripheral nerves. A review article","authors":"O. Galibin, G. V. Medvedev, P. Popryadukhin, P. A. Kulagin, A. Gusev, Galina P. Kossyakova, N. Mikhailova, V. D. Novak, D. N. Solomitskiy, I. O. Shemiakin, V. Gadzhiagaev, M. K. Gurbannazarov, St. Petersburg Russia Orthopedy","doi":"10.18620/CTT-1866-8836-2019-8-1-20-25","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-20-25","url":null,"abstract":"CTT JOURNAL | VOLUME 8 | NUMBER 1 | MARCH-APRIL 2019 Oleg V. Galibin 1, German V. Medvedev 2, Pavel V. Popryadukhin 3, Pavel A. Kulagin 1, Alexandr A. Gusev 1, Galina P. Kossyakova 1, Natalia V. Mikhailova 1, Veronika D. Novak 1, Denis N. Solomitskiy 1, Igor O. Shemiakin 1, Vadim S. Gadzhiagaev 1, Maksat Kh. Gurbannazarov 1 1 First St. Petersburg State I. Pavlov Medical University, St. Petersburg, Russia 2 Russian R. R.Wreden Research Institute of Traumatology and Orthopedy, St. Petersburg, Russia 3 Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia Alternative approaches to overcome diastasis of damaged peripheral nerves. A review article Cellular Th erapy and Transplantation (CTT). Vol. 8, No. 1, 2019 doi: 10.18620/ctt-1866-8836-2019-8-1-20-25 Submitted: 26 November 2018, accepted: 15 March 2019","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85223998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent developments in transplant-associated thrombotic microangiopathy 移植相关血栓性微血管病的最新进展
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-8-11
R. Ruutu
{"title":"Recent developments in transplant-associated thrombotic microangiopathy","authors":"R. Ruutu","doi":"10.18620/CTT-1866-8836-2019-8-1-8-11","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-8-11","url":null,"abstract":"microangiopathy (TA-TMA) is a relatively common complication of hematopoietic stem cell transplantation. Th e pathophysiology is complex, the central feature is endothelial injury. Th e role of complement activation in the pathophysiology has been increasingly recognized. Th e diagnostic procedures and interpretations vary considerably between centers, and aims at standardizing the criteria of this complication are important especially for study purposes. Th e therapy is improving, particularly due to the introduction of complement inhibitors. Howev-er, the indications and policy of administration of these drugs are not well established and need further study.","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81787678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Incidence, diagnosis and treatment of sinusitis in children and adolescents after hematopoietic stem cell transplantation 儿童和青少年造血干细胞移植后鼻窦炎的发病率、诊断和治疗
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-46-53
E. Utimisheva, O. Dolgov, O. Paina, K. Ekushov, A. Vitrischak, B. Smirnov, L. Zubarovskaya, S. Karpischenko, B. Afanasyev
{"title":"Incidence, diagnosis and treatment of sinusitis in children and adolescents after hematopoietic stem cell transplantation","authors":"E. Utimisheva, O. Dolgov, O. Paina, K. Ekushov, A. Vitrischak, B. Smirnov, L. Zubarovskaya, S. Karpischenko, B. Afanasyev","doi":"10.18620/CTT-1866-8836-2019-8-1-46-53","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-46-53","url":null,"abstract":"of the causative bacterial agents in sinusitis was more likely in adolescent patients, in comparison to the younger children group. Th e severity of changes in paranasal sinuses, as registered with computed tomography aft er 100 days aft er allo-HSCT, was more pronounced (p=0.014) than at earlier terms, thus being discordant with less common clinical signs of sinusitis (p=0.008), and milder clinical course of sinusitis assessed by a visual analogue scale (p=0.032) during this period. Punctures of maxillary sinuses combined with antimicrobial therapy proved to shorten the duration of sinusitis treatment in these patients (p=0.024)","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79482945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitotic activity of thoracic duct cells in rabbits correlates with age and total lymphocyte numbers 家兔胸导管细胞有丝分裂活性与年龄和淋巴细胞总数有关
Cellular Therapy and Transplantation Pub Date : 2019-03-30 DOI: 10.18620/CTT-1866-8836-2019-8-1-58-65
A. V. Kuznetsov, Ildar Fakhradiyev, Y. Almabayev, A. Almabayeva
{"title":"Mitotic activity of thoracic duct cells in rabbits correlates with age and total lymphocyte numbers","authors":"A. V. Kuznetsov, Ildar Fakhradiyev, Y. Almabayev, A. Almabayeva","doi":"10.18620/CTT-1866-8836-2019-8-1-58-65","DOIUrl":"https://doi.org/10.18620/CTT-1866-8836-2019-8-1-58-65","url":null,"abstract":"CTT JOURNAL | VOLUME 8 | NUMBER 1 | MARCH-APRIL 2019 Alexander V. Kuznetsov 1, Ildar R. Fakhradiyev 2, Ydyrys A. Almabayev 3, Aigul Y. Almabayeva 4 1 Department of Human Anatomy, Novosibirsk State Medical University, Russia 2 Laboratory of Experimental Medicine, Kazakh National Medical University, Republic of Kazakhstan 3 Department of Clinical Anatomy, Kazakh National Medical University, Republic of Kazakhstan 4 Department of Human Anatomy with O.S. Medical University Astana, Republic of Kazakhstan Mitotic activity of thoracic duct cells in rabbits correlates with age and total lymphocyte numbers Cellular Th erapy and Transplantation (CTT). Vol. 8, No. 1, 2019 doi: 10.18620/ctt-1866-8836-2019-8-1-58-65 Submitted: 20 March 2019, accepted: 15 April 2019","PeriodicalId":39111,"journal":{"name":"Cellular Therapy and Transplantation","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84652173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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