Incidence, diagnosis and treatment of sinusitis in children and adolescents after hematopoietic stem cell transplantation

Abstract

of the causative bacterial agents in sinusitis was more likely in adolescent patients, in comparison to the younger children group. Th e severity of changes in paranasal sinuses, as registered with computed tomography aft er 100 days aft er allo-HSCT, was more pronounced (p=0.014) than at earlier terms, thus being discordant with less common clinical signs of sinusitis (p=0.008), and milder clinical course of sinusitis assessed by a visual analogue scale (p=0.032) during this period. Punctures of maxillary sinuses combined with antimicrobial therapy proved to shorten the duration of sinusitis treatment in these patients (p=0.024)